Mlst8 (MTOR associated protein MLST8) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Mlst8 (MTOR associated protein MLST8) Rattus norvegicus
Analyze
Symbol: Mlst8
Name: MTOR associated protein MLST8 (Ensembl:MTOR associated protein, LST8 homolog)
RGD ID: 69242
Description: Predicted to enable protein serine/threonine kinase activator activity and protein-macromolecule adaptor activity. Predicted to be involved in TOR signaling; positive regulation of TOR signaling; and regulation of actin cytoskeleton organization. Predicted to act upstream of or within phosphatidylinositol 3-kinase/protein kinase B signal transduction; positive regulation of actin filament polymerization; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in cytoplasm. Orthologous to human MLST8 (MTOR associated protein, LST8 homolog); PARTICIPATES IN mTOR signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: G beta-like protein; G protein beta subunit-like; Gbl; mammalian lethal with SEC13 protein 8; MGC114322; MTOR associated protein, LST8 homolog; MTOR associated protein, LST8 homolog (S. cerevisiae); protein GbetaL; target of rapamycin complex subunit LST8; TORC subunit LST8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,002,927 - 14,008,678 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1014,002,938 - 14,008,678 (-)EnsemblGRCr8
mRatBN7.21013,498,377 - 13,504,128 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,498,388 - 13,504,128 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1018,244,945 - 18,250,695 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,733,790 - 17,739,540 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,232,975 - 13,238,725 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,839,250 - 13,845,001 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,839,250 - 13,845,001 (-)Ensemblrn6Rnor6.0
Rnor_5.01013,656,236 - 13,661,987 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41013,725,510 - 13,731,261 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1013,178,857 - 13,184,608 (-)NCBICelera
RGSC_v3.11013,725,520 - 13,731,261 (-)NCBI
Cytogenetic Map10q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA,IEA)
lysosomal membrane  (IEA)
TORC1 complex  (IBA,IEA,ISO)
TORC2 complex  (IBA,IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Kim DH, etal., Mol Cell. 2003 Apr;11(4):895-904.
3. mTOR signaling in growth control and disease. Laplante M and Sabatini DM, Cell. 2012 Apr 13;149(2):274-93. doi: 10.1016/j.cell.2012.03.017.
4. Molecular mechanisms of mTOR-mediated translational control. Ma XM and Blenis J, Nat Rev Mol Cell Biol. 2009 May;10(5):307-18. Epub 2009 Apr 2.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Insulin regulation of a novel WD-40 repeat protein in adipocytes. Rodgers BD, etal., J Endocrinol 2001 Feb;168(2):325-32.
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:12477932   PMID:15467718   PMID:21779001   PMID:24036451  


Genomics

Comparative Map Data
Mlst8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,002,927 - 14,008,678 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1014,002,938 - 14,008,678 (-)EnsemblGRCr8
mRatBN7.21013,498,377 - 13,504,128 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,498,388 - 13,504,128 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1018,244,945 - 18,250,695 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,733,790 - 17,739,540 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,232,975 - 13,238,725 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,839,250 - 13,845,001 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,839,250 - 13,845,001 (-)Ensemblrn6Rnor6.0
Rnor_5.01013,656,236 - 13,661,987 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41013,725,510 - 13,731,261 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1013,178,857 - 13,184,608 (-)NCBICelera
RGSC_v3.11013,725,520 - 13,731,261 (-)NCBI
Cytogenetic Map10q12NCBI
MLST8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,205,454 - 2,209,453 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,204,248 - 2,209,453 (+)Ensemblhg38GRCh38
GRCh37162,255,455 - 2,259,454 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,195,451 - 2,199,419 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34162,195,495 - 2,199,414NCBI
Celera162,469,868 - 2,473,835 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,181,357 - 2,185,596 (+)NCBIHuRef
CHM1_1162,255,106 - 2,259,344 (+)NCBICHM1_1
T2T-CHM13v2.0162,227,913 - 2,231,910 (+)NCBIT2T-CHM13v2.0
Mlst8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,692,524 - 24,698,722 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,692,525 - 24,698,052 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381724,473,550 - 24,479,114 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,473,551 - 24,479,078 (-)Ensemblmm10GRCm38
MGSCv371724,610,496 - 24,616,023 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361724,201,153 - 24,206,678 (-)NCBIMGSCv36mm8
Celera1724,989,327 - 24,994,854 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.39NCBI
Mlst8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,056,363 - 15,060,300 (-)Ensembl
ChiLan1.0NW_00495544215,056,363 - 15,060,300 (-)NCBIChiLan1.0ChiLan1.0
MLST8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,707,554 - 2,712,302 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,488,454 - 6,493,202 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,063,534 - 1,067,706 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,306,451 - 2,310,828 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,306,451 - 2,310,828 (+)EnsemblpanPan2panpan1.1
MLST8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,759,713 - 38,765,556 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,762,103 - 38,765,488 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha639,999,004 - 40,004,847 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0639,068,199 - 39,074,042 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,068,201 - 39,073,985 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,753,209 - 38,759,052 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,725,535 - 38,731,378 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,204,256 - 39,210,099 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mlst8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,859,878 - 104,872,523 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,834,701 - 1,842,719 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,839,135 - 1,849,307 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MLST8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,778,754 - 39,788,285 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1339,778,746 - 39,786,206 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,394,842 - 42,398,552 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MLST8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,101,044 - 2,105,272 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,101,891 - 2,105,739 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606828,956,518 - 28,960,758 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mlst8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462491347,962 - 55,048 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462491350,622 - 54,643 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mlst8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v191,758,322 - 1,764,046 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mlst8
10 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:775
Count of miRNA genes:290
Interacting mature miRNAs:376
Transcripts:ENSRNOT00000014269
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat

Markers in Region
AA957863  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,498,417 - 13,498,606 (+)MAPPERmRatBN7.2
Rnor_6.01013,839,291 - 13,839,479NCBIRnor6.0
Rnor_5.01013,656,277 - 13,656,465UniSTSRnor5.0
RGSC_v3.41013,725,551 - 13,725,739UniSTSRGSC3.4
Celera1013,178,898 - 13,179,086UniSTS
RH 3.4 Map10174.1UniSTS
Cytogenetic Map10q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000014269   ⟹   ENSRNOP00000014269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,498,399 - 13,503,256 (-)Ensembl
Rnor_6.0 Ensembl1013,839,250 - 13,845,001 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101517   ⟹   ENSRNOP00000078598
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1014,002,938 - 14,008,678 (-)Ensembl
mRatBN7.2 Ensembl1013,498,388 - 13,504,128 (-)Ensembl
RefSeq Acc Id: NM_022404   ⟹   NP_071799
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,002,927 - 14,008,678 (-)NCBI
mRatBN7.21013,498,377 - 13,504,128 (-)NCBI
Rnor_6.01013,839,250 - 13,845,001 (-)NCBI
Rnor_5.01013,656,236 - 13,661,987 (-)NCBI
RGSC_v3.41013,725,510 - 13,731,261 (-)RGD
Celera1013,178,857 - 13,184,608 (-)RGD
Sequence:
RefSeq Acc Id: XM_017597522   ⟹   XP_017453011
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,002,939 - 14,008,373 (-)NCBI
mRatBN7.21013,498,383 - 13,503,822 (-)NCBI
Rnor_6.01013,839,250 - 13,844,644 (-)NCBI
Sequence:
RefSeq Acc Id: NP_071799   ⟸   NM_022404
- UniProtKB: Q4QRA0 (UniProtKB/Swiss-Prot),   Q9Z2K5 (UniProtKB/Swiss-Prot),   A0A8I5ZL90 (UniProtKB/TrEMBL),   A6HCT2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453011   ⟸   XM_017597522
- Peptide Label: isoform X1
- UniProtKB: Q9Z2K5 (UniProtKB/Swiss-Prot),   Q4QRA0 (UniProtKB/Swiss-Prot),   A0A8I5ZL90 (UniProtKB/TrEMBL),   A6HCT2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014269   ⟸   ENSRNOT00000014269
Ensembl Acc Id: ENSRNOP00000078598   ⟸   ENSRNOT00000101517

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z2K5-F1-model_v2 AlphaFold Q9Z2K5 1-326 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697012
Promoter ID:EPDNEW_R7537
Type:initiation region
Name:Mlst8_1
Description:MTOR associated protein, LST8 homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01013,844,687 - 13,844,747EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69242 AgrOrtholog
BioCyc Gene G2FUF-25856 BioCyc
Ensembl Genes ENSRNOG00000009667 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000101517 ENTREZGENE
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7455095 IMAGE-MGC_LOAD
InterPro G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot
  MLST8 UniProtKB/Swiss-Prot
  Quinoprotein_ADH-like_supfam UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_CS UniProtKB/Swiss-Prot
KEGG Report rno:64226 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114322 IMAGE-MGC_LOAD
NCBI Gene 64226 ENTREZGENE
PANTHER PTHR19842 UniProtKB/Swiss-Prot
  TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 UniProtKB/Swiss-Prot
Pfam WD40 UniProtKB/Swiss-Prot
PhenoGen Mlst8 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009667 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50998 UniProtKB/Swiss-Prot
TIGR TC206565
UniProt A0A8I5ZL90 ENTREZGENE, UniProtKB/TrEMBL
  A6HCT2 ENTREZGENE, UniProtKB/TrEMBL
  LST8_RAT UniProtKB/Swiss-Prot
  Q4QRA0 ENTREZGENE
  Q9Z2K5 ENTREZGENE
UniProt Secondary Q4QRA0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Mlst8  MTOR associated protein MLST8  Mlst8  MTOR associated protein, LST8 homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-01 Mlst8  MTOR associated protein, LST8 homolog  Mlst8  MTOR associated protein, LST8 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-12 Mlst8  MTOR associated protein, LST8 homolog (S. cerevisiae)  Gbl  G protein beta subunit-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Gbl  G protein beta subunit-like      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains G-protein beta subunits with seven WD-40 repeats 68781
gene_expression mRNA highly expressed in the brain and testis 68781
gene_process mediates some actions of insulin 68781