Cacna1b Rat Gene (calcium channel, voltage-dependent, N type, alpha 1B subunit)

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Keyword

Gene:
Cacna1b ( Rattus norvegicus )
calcium channel, voltage-dependent, N type, alpha 1B subunit
Description: voltage gated calcium channel subunit; involved in controlling calcium-dependent neurotransmitter release throughout the nervous system
ArrayIDs: 6498245; 5803586; 6680539; 6476900; 6326611; 6047224; 6073667; 5699327; 5856789; 6716140; 1370444_at; 6146157; 5705366; 6370147; 6554600; 5845214; 6680638; 5681197; 5693289; AF055477_at; 6393218; 5998194; 6547963; 5719705; 6337671; 5953563; 6442572; 6552597; 1371175_a_at; 5895445; 5652403; 6567583; 6071161; 5971321; 5628855; 5978791; 5653883; 6634697; 5709783; 6504476; 5784178; 6195943; 5690407; 6098253; 6378756; 6330424; 6700864; 6452785; 6515344; M92905_s_at; 5805807; 5693682; 5919376; 6230828; 6624579; 6724135; 5685144; 6648581;  (details...)
Gene Type: protein-coding

Additional Data

Homologs
Homo sapiens: CACNA1B     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Cacna1b     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Cacna1b Rat Celera Assembly 3 2215807 - 2379081
RGSC genome assembly v3.4 3 2852771 - 3039756
Cytogenetic 3 p13
genome assembly 3.1 3 2873390 - 3039747
Mus musculus Cacna1b Mouse genome assembly build 36.1 2 24461895 - 24618672
Cytogenetic 2 2 A2
Homo sapiens CACNA1B human genome assembly 9 138048077 - 138292468
Human genome assembly build 36.2 9 139892062 - 140136449
Cytogenetic 9 q34

View comparative maps:      NCBI MapViewer

Genome
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Annotation
Molecular Function

Gene Ontology

voltage-gated calcium channel activity,  protein binding,  nucleotide binding ... (details...)
Biological Process

Gene Ontology

regulation of blood pressure,  locomotory behavior,  positive regulation of neurotransmitter secretion ... (details...)
Cellular Component

Gene Ontology

dendritic shaft,  integral to membrane,  plasma membrane ... (details...)
Disease

Ontology

Multiple Sclerosis,  Hyperalgesia,  Encephalomyelitis, Experimental Autoimmune ... (details...)
Phenotype

Ontology

abnormal axon morphology,  demyelination (details...)

External Links
Databases
DATABASE ID SOURCE
PROSITE: EF_HAND_2 IPI
UNIPARC: UPI0001B7B1FA IPI
UNIPARC: UPI0001B7B1FD IPI
UNIPARC: UPI00000E7010 IPI
UNIPARC: UPI0001B7B1FC IPI
UNIPARC: UPI000022FACE IPI
UNIPARC: UPI0001B7B1FE IPI
UNIPARC: UPI0000127269 IPI
KEGG Report: rno:257648 ENTREZGENE
HomoloGene Group ID: 20184 ENTREZGENE
Germonline: 628852
Pfam: Ion_trans IPI
KEGG Pathway: 04930 ENTREZGENE
KEGG Pathway: 04742 ENTREZGENE
KEGG Pathway: 04010 ENTREZGENE
KEGG Pathway: 04020 ENTREZGENE
InterPro: EF_HAND_2. IPI
InterPro: Ion_trans. IPI
InterPro: VDCC_N_a1su. IPI
InterPro: VDCCAlpha1. IPI
IPI: IPI00948114 IPI
IPI: IPI00326569 IPI
IPI: IPI00204129 IPI
IPI: IPI00565585 IPI
IPI: IPI00454370 IPI
IPI: IPI00476965 IPI
IPI: IPI00200639 IPI
Ensembl Protein: ENSRNOP00000041710 IPI
Ensembl Protein: ENSRNOP00000006162 IPI
Ensembl Protein: ENSRNOP00000063686 IPI
Ensembl Protein: ENSRNOP00000044223 IPI
Ensembl Protein: ENSRNOP00000045615 IPI
Ensembl Protein: ENSRNOP00000046546 IPI
Entrez Gene: Cacna1b ENTREZGENE
UniProt: Q9JIK0_RAT IPI
UniProt: Q9JIJ9_RAT IPI
UniProt: Q923W2_RAT IPI
UniProt: O89089_RAT IPI
UniProt: Q6XS92_RAT IPI
UniProt: Q9R1B6_RAT IPI
UniProt: Q9R1B5_RAT IPI
UniProt: Q6XS93_RAT IPI
UniProt: CAC1B_RAT IPI
Ensembl Genes: ENSRNOG00000004560 IPI
PANTHER: NVDCCAlpha1 IPI
BIND: 130592
BIND: 128230
PRINTS: CACHANNEL. IPI
PRINTS: NVDCCALPHA1. IPI
Sequences
Nucleotide: M92905 Get FASTA Search GEO Profiles
Nucleotide: FJ431206 Get FASTA Search GEO Profiles
Nucleotide: AY211500 Get FASTA Search GEO Profiles
Nucleotide: AF389419 Get FASTA Search GEO Profiles
Nucleotide: AF222337 Get FASTA Search GEO Profiles
Nucleotide: AF055477 Get FASTA Search GEO Profiles
Nucleotide: CS184990 Get FASTA Search GEO Profiles
Nucleotide: AY211499 Get FASTA Search GEO Profiles
Nucleotide: AF222338 Get FASTA Search GEO Profiles
Nucleotide: AF146633 Get FASTA Search GEO Profiles
Nucleotide: AF146632 Get FASTA Search GEO Profiles
Nucleotide: NM_147141 Get FASTA Search GEO Profiles
(View all 12 Nucleotide Accessions)
Protein: Q9R1B6 Get FASTA
Protein: Q9R1B5 Get FASTA
Protein: Q9JIK0 Get FASTA
Protein: Q9JIJ9 Get FASTA
Protein: Q923W2 Get FASTA
Protein: Q6XS93 Get FASTA
Protein: Q6XS92 Get FASTA
Protein: Q02294 Get FASTA
Protein: O89089 Get FASTA
Protein: AAA42014 Get FASTA
Protein: ACJ61258 Get FASTA
Protein: AAO53230 Get FASTA
Protein: AAK71643 Get FASTA
Protein: AAF70136 Get FASTA
Protein: AAC29043 Get FASTA
Protein: CAJ41867 Get FASTA
Protein: AAO53229 Get FASTA
Protein: AAO53228 Get FASTA
Protein: AAF70137 Get FASTA
Protein: AAD31923 Get FASTA
Protein: AAD31922 Get FASTA
Protein: NP_671482 Get FASTA
(View all 22 Protein Accessions)
Clusters
UniGene: 85880

References
Curated References
15 references in RGD related to Cacna1b

Other References
31 other references at PubMed related to Cacna1b

Database Information
RGD ID 628852
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

14-DEC-04: Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit APPROVED Symbol and Name status set to approved 1299863

27-FEB-03: Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit PROVISIONAL Symbol and Name status set to provisional 70820