Il13ra1 (interleukin 13 receptor subunit alpha 1) - Rat Genome Database

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Gene: Il13ra1 (interleukin 13 receptor subunit alpha 1) Rattus norvegicus
Analyze
Symbol: Il13ra1 (Ensembl: Il13ra1-ps1)
Name: interleukin 13 receptor subunit alpha 1 (Ensembl:interleukin 13 receptor subunit alpha 1, pseudogene 1)
RGD ID: 628741
Description: Enables interleukin-13 receptor activity. Involved in positive regulation of B cell proliferation and positive regulation of immunoglobulin production. Human ortholog(s) of this gene implicated in asthma and chronic obstructive pulmonary disease. Orthologous to human IL13RA1 (interleukin 13 receptor subunit alpha 1); PARTICIPATES IN interleukin-4 signaling pathway; cytokine mediated signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2-amino-2-deoxy-D-glucopyranose.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: interleukin 13 receptor, alpha 1; interleukin-13 receptor subunit alpha-1; MGC105309
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Il13ra1-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X120,213,670 - 120,294,777 (+)NCBIGRCr8
mRatBN7.2X115,348,822 - 115,408,682 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1171,254,928 - 71,258,678 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 EnsemblX115,348,860 - 115,408,681 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX117,450,135 - 117,510,865 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X121,019,209 - 121,079,947 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X118,565,417 - 118,626,152 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X122,724,081 - 122,783,801 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX122,724,129 - 122,781,479 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X122,873,725 - 122,933,124 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X8,758,662 - 8,820,545 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X8,764,214 - 8,826,101 (-)NCBI
CeleraX114,585,012 - 114,644,379 (+)NCBICelera
Cytogenetic MapXq34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
benzene  (EXP)
benzo[a]pyrene  (ISO)
beta-D-glucosamine  (EXP)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
Brevianamide A  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
Calcimycin  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
fipronil  (EXP)
fluoranthene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
Fulvic acid  (ISO)
furan  (EXP)
heptachlor  (EXP)
imiquimod  (ISO)
irinotecan  (EXP)
isotretinoin  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury(1+)  (EXP)
microcystin-LR  (ISO)
mycotoxin  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP,ISO)
protein kinase inhibitor  (ISO)
raloxifene  (ISO)
SB 431542  (ISO)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
Soman  (EXP)
succimer  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
tibolone  (ISO)
titanium dioxide  (ISO)
TMC-120A  (ISO)
toluene  (EXP)
topotecan  (EXP)
torcetrapib  (ISO)
trans-ferulic acid  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Novel polymorphism in the coding region of the IL-13 receptor alpha' gene: association study with atopic asthma in the Japanese population. Ahmed S, etal., Exp Clin Immunogenet. 2000;17(1):18-22.
2. Polymorphisms in IL13 pathway genes in asthma and chronic obstructive pulmonary disease. Beghe B, etal., Allergy. 2010 Apr;65(4):474-81. Epub 2009 Oct 1.
3. IL-13 fusion cytotoxin ameliorates chronic fungal-induced allergic airway disease in mice. Blease K, etal., J Immunol. 2001 Dec 1;167(11):6583-92.
4. Polymorphisms in the interleukin 4, interleukin 13, and corresponding receptor genes are not associated with systemic sclerosis and do not influence gene expression. Broen JC, etal., J Rheumatol. 2012 Jan;39(1):112-8. doi: 10.3899/jrheum.110235. Epub 2011 Nov 1.
5. Upregulation of interleukin-13 receptor chains in bronchial smooth muscle tissues of mouse experimental asthma. Chiba Y, etal., J Smooth Muscle Res. 2010;46(1):49-55.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling. Graham BB, etal., Am J Pathol. 2010 Sep;177(3):1549-61. Epub 2010 Jul 29.
9. IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome. Keane MP, etal., J Immunol. 2007 Jan 1;178(1):511-9.
10. Gene-gene interaction between IL-13 and IL-13Ralpha1 is associated with total IgE in Korean children with atopic asthma. Kim HB, etal., J Hum Genet. 2006;51(12):1055-62. Epub 2006 Sep 28.
11. Genetic association studies of interleukin-13 receptor alpha1 subunit gene polymorphisms in asthma and atopy. Konstantinidis AK, etal., Eur Respir J. 2007 Jul;30(1):40-7. Epub 2007 Mar 28.
12. Analysis of polymorphisms in olive pollen allergy: IL13, IL4RA, IL5 and ADRB2 genes. Llanes E, etal., Int Arch Allergy Immunol. 2009;148(3):228-38. doi: 10.1159/000161583. Epub 2008 Oct 10.
13. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
14. Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis. Munitz A, etal., Proc Natl Acad Sci U S A. 2008 May 20;105(20):7240-5. Epub 2008 May 14.
15. Limited systemic sclerosis patients with pulmonary arterial hypertension show biomarkers of inflammation and vascular injury. Pendergrass SA, etal., PLoS One. 2010 Aug 17;5(8):e12106.
16. Expression of a functional IL-13Ralpha1 by rat B cells. Pierrot C, etal., Biochem Biophys Res Commun 2001 Oct 5;287(4):969-76.
17. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
18. GOA pipeline RGD automated data pipeline
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. Comprehensive gene review and curation RGD comprehensive gene curation
21. Up-regulation of interleukin-13 receptor alpha1 on human keratinocytes in the skin of psoriasis and atopic dermatitis. Wongpiyabovorn J, etal., J Dermatol Sci. 2003 Oct;33(1):31-40.
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Il13ra1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X120,213,670 - 120,294,777 (+)NCBIGRCr8
mRatBN7.2X115,348,822 - 115,408,682 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1171,254,928 - 71,258,678 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 EnsemblX115,348,860 - 115,408,681 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX117,450,135 - 117,510,865 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X121,019,209 - 121,079,947 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X118,565,417 - 118,626,152 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X122,724,081 - 122,783,801 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX122,724,129 - 122,781,479 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X122,873,725 - 122,933,124 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X8,758,662 - 8,820,545 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X8,764,214 - 8,826,101 (-)NCBI
CeleraX114,585,012 - 114,644,379 (+)NCBICelera
Cytogenetic MapXq34NCBI
IL13RA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X118,727,606 - 118,805,228 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX118,727,133 - 118,794,535 (+)EnsemblGRCh38hg38GRCh38
GRCh37X117,861,569 - 117,928,496 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X117,745,587 - 117,812,524 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X117,643,440 - 117,710,378NCBI
CeleraX118,316,317 - 118,383,340 (+)NCBICelera
Cytogenetic MapXq24NCBI
HuRefX107,355,737 - 107,421,582 (+)NCBIHuRef
CHM1_1X117,772,468 - 117,839,397 (+)NCBICHM1_1
T2T-CHM13v2.0X117,105,336 - 117,182,975 (+)NCBIT2T-CHM13v2.0
Il13ra1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X35,375,761 - 35,434,915 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX35,375,763 - 35,434,912 (+)EnsemblGRCm39 Ensembl
GRCm38X36,112,108 - 36,171,262 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX36,112,110 - 36,171,259 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X33,652,134 - 33,711,257 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X32,543,584 - 32,602,707 (+)NCBIMGSCv36mm8
CeleraX22,841,197 - 22,900,025 (+)NCBICelera
Cytogenetic MapXA3.3NCBI
cM MapX20.49NCBI
Il13ra1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555341,160,340 - 1,204,911 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555341,157,758 - 1,205,158 (-)NCBIChiLan1.0ChiLan1.0
IL13RA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X118,085,884 - 118,164,235 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X118,089,492 - 118,167,836 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X107,735,233 - 107,813,282 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X118,195,828 - 118,269,449 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX118,202,285 - 118,266,770 (+)Ensemblpanpan1.1panPan2
IL13RA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X90,925,497 - 90,981,855 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX90,924,801 - 90,979,963 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX77,001,059 - 77,055,772 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X92,665,536 - 92,720,247 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX92,665,506 - 92,720,247 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X90,118,717 - 90,173,430 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X91,877,457 - 91,932,160 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X91,605,785 - 91,660,491 (+)NCBIUU_Cfam_GSD_1.0
Il13ra1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X89,878,479 - 89,937,244 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647911,050,249 - 11,108,909 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647911,052,077 - 11,108,915 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL13RA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX97,300,466 - 97,356,133 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X97,300,960 - 97,353,754 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X114,333,596 - 114,386,429 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL13RA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606531,471,060 - 31,545,965 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il13ra1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248952,706,043 - 2,763,798 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248952,706,225 - 2,763,489 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Il13ra1
109 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:825
Count of miRNA genes:309
Interacting mature miRNAs:421
Transcripts:ENSRNOT00000017746
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX112934952138400867Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
5685004Bss104Bone structure and strength QTL 1043.9tibia area (VT:1000281)tibia area measurement (CMO:0001382)X113805422126975220Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
12 12 54 56 48 24 12 24 12 95 48 30 11 31 24

Sequence


RefSeq Acc Id: NM_145789   ⟹   NP_665732
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X120,214,605 - 120,274,461 (+)NCBI
mRatBN7.2X115,348,822 - 115,408,682 (+)NCBI
Rnor_6.0X122,724,081 - 122,783,801 (+)NCBI
Rnor_5.0X122,873,725 - 122,933,124 (+)NCBI
RGSC_v3.4X8,758,662 - 8,820,545 (-)RGD
CeleraX114,585,012 - 114,644,379 (+)RGD
Sequence:
RefSeq Acc Id: XM_063279821   ⟹   XP_063135891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X120,213,670 - 120,294,777 (+)NCBI
Protein Sequences
Protein RefSeqs NP_665732 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135891 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH93615 (Get FASTA)   NCBI Sequence Viewer  
  EDM10800 (Get FASTA)   NCBI Sequence Viewer  
  EDM10801 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017746.5
  ENSRNOP00000070979.1
  ENSRNOP00000087106.1
RefSeq Acc Id: NP_665732   ⟸   NM_145789
- Peptide Label: precursor
- UniProtKB: Q561K3 (UniProtKB/TrEMBL),   A0A0G2JZB2 (UniProtKB/TrEMBL),   Q8VHC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_063135891   ⟸   XM_063279821
- Peptide Label: isoform X1
Protein Domains
Interleukin-13 receptor subunit alpha-1 Ig-like   Type I cytokine receptor cytokine-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q561K3-F1-model_v2 AlphaFold Q561K3 1-426 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701978
Promoter ID:EPDNEW_R12501
Type:initiation region
Name:Il13ra1_1
Description:interleukin 13 receptor subunit alpha 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X122,724,066 - 122,724,126EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628741 AgrOrtholog
BioCyc Gene G2FUF-1324 BioCyc
Ensembl Genes ENSRNOG00000001713 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000013170 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002330.6 UniProtKB/TrEMBL
  ENSRNOT00000017746.7 UniProtKB/TrEMBL
  ENSRNOT00000112175.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7310384 IMAGE-MGC_LOAD
InterPro FN3_sf UniProtKB/TrEMBL
  FN_III UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Il13Ra_Ig UniProtKB/TrEMBL
  IL6_recept_bd UniProtKB/TrEMBL
  Short_hematopoietin_rcpt_2_CS UniProtKB/TrEMBL
KEGG Report rno:252963 UniProtKB/TrEMBL
MGC_CLONE MGC:105309 IMAGE-MGC_LOAD
NCBI Gene 252963 ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  ERYTHROPOIETIN RECEPTOR UniProtKB/TrEMBL
  PTHR23037:SF35 UniProtKB/TrEMBL
Pfam Il13Ra_Ig UniProtKB/TrEMBL
  IL6Ra-bind UniProtKB/TrEMBL
PhenoGen Il13ra1 PhenoGen
PROSITE HEMATOPO_REC_S_F2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001713 RatGTEx
  ENSRNOG00000013170 RatGTEx
Superfamily-SCOP FN_III-like UniProtKB/TrEMBL
UniProt A0A0G2JZB2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A7D4_RAT UniProtKB/TrEMBL
  A6JMD9_RAT UniProtKB/TrEMBL
  Q561K3 ENTREZGENE, UniProtKB/TrEMBL
  Q8VHC2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-16 Il13ra1  interleukin 13 receptor subunit alpha 1  Il13ra1  interleukin 13 receptor, alpha 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Il13ra1  interleukin 13 receptor, alpha 1      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Il13ra1  interleukin 13 receptor, alpha 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains short intracellular domain with a proline rich motif and two conserved tyrosine residues 633067
gene_expression mRNA and protein is expressed in rat B cells 633067
gene_homology cDNA is 86.8% similar to mouse and 72.4% similar to the human gene 633067