Cngb1 (cyclic nucleotide gated channel subunit beta 1) - Rat Genome Database

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Gene: Cngb1 (cyclic nucleotide gated channel subunit beta 1) Rattus norvegicus
Analyze
Symbol: Cngb1
Name: cyclic nucleotide gated channel subunit beta 1
RGD ID: 621809
Description: Enables cyclic nucleotide binding activity and intracellularly cyclic nucleotide-activated monoatomic cation channel activity. Involved in metal ion transport and regulation of cytosolic calcium ion concentration. Located in non-motile cilium membrane and terminal bouton. Part of intracellular cyclic nucleotide activated cation channel complex. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 45. Orthologous to human CNGB1 (cyclic nucleotide gated channel subunit beta 1); PARTICIPATES IN altered visual phototransduction pathway; calcium/calcium-mediated signaling pathway; retinitis pigmentosa pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CNG channel 4; CNG-4; CNG4; cyclic nucleotide gated channel beta 1; cyclic nucleotide-gated cation channel 4; cyclic nucleotide-gated cation channel beta-1; cyclic nucleotide-gated channel beta subunit 1; cyclic nucleotide-gated channel beta-1; gene model 1959, (NCBI); Gm1959; LOC360297
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8199,732,646 - 9,798,864 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl199,732,646 - 9,797,224 (+)EnsemblGRCr8
mRatBN7.2199,726,595 - 9,791,111 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,726,595 - 9,791,173 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx199,691,498 - 9,755,704 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01910,458,328 - 10,522,528 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0199,744,658 - 9,808,868 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01910,142,440 - 10,206,618 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1910,142,496 - 10,206,681 (+)Ensemblrn6Rnor6.0
Rnor_5.01910,126,285 - 10,190,852 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41910,186,416 - 10,257,296 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera199,619,420 - 9,683,573 (+)NCBICelera
RGSC_v3.11910,191,241 - 10,262,122NCBI
Cytogenetic Map19p13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Segregation of a mutation in CNGB1 encoding the beta-subunit of the rod cGMP-gated channel in a family with autosomal recessive retinitis pigmentosa. Bareil C, etal., Hum Genet 2001 Apr;108(4):328-34.
2. Calcium signalling remodelling and disease. Berridge MJ Biochem Soc Trans. 2012 Apr;40(2):297-309. doi: 10.1042/BST20110766.
3. The native rat olfactory cyclic nucleotide-gated channel is composed of three distinct subunits. Bonigk W, etal., J Neurosci 1999 Jul 1;19(13):5332-47.
4. Genes and mutations causing retinitis pigmentosa. Daiger SP, etal., Clin Genet. 2013 Aug;84(2):132-41. doi: 10.1111/cge.12203. Epub 2013 Jun 19.
5. Ca2+ permeation in cyclic nucleotide-gated channels. Dzeja C, etal., EMBO J. 1999 Jan 4;18(1):131-44. doi: 10.1093/emboj/18.1.131.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Cyclic nucleotide-gated ion channels. Kaupp UB and Seifert R, Physiol Rev. 2002 Jul;82(3):769-824.
8. Functional cGMP-gated channels in cerebellar granule cells. Lopez-Jimenez ME, etal., J Cell Physiol. 2012 May;227(5):2252-63. doi: 10.1002/jcp.22964.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Deciphering the function of the CNGB1b subunit in olfactory CNG channels. Nache V, etal., Sci Rep. 2016 Jul 11;6:29378. doi: 10.1038/srep29378.
11. Differential regulation by cyclic nucleotides of the CNGA4 and CNGB1b subunits in olfactory cyclic nucleotide-gated channels. Nache V, etal., Sci Signal. 2012 Jul 10;5(232):ra48. doi: 10.1126/scisignal.2003110.
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
15. GOA pipeline RGD automated data pipeline
16. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. Comprehensive gene review and curation RGD comprehensive gene curation
19. An isoform of the rod photoreceptor cyclic nucleotide-gated channel beta subunit expressed in olfactory neurons. Sautter A, etal., Proc Natl Acad Sci U S A 1998 Apr 14;95(8):4696-701.
20. Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait. Wright AF, etal., Nat Rev Genet. 2010 Apr;11(4):273-84. doi: 10.1038/nrg2717.
21. Stoichiometry and assembly of olfactory cyclic nucleotide-gated channels. Zheng J and Zagotta WN, Neuron. 2004 May 13;42(3):411-21. doi: 10.1016/s0896-6273(04)00253-3.
Additional References at PubMed
PMID:9379842   PMID:15557452   PMID:15634774   PMID:16980309   PMID:22183407   PMID:23178122   PMID:24164424  


Genomics

Comparative Map Data
Cngb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8199,732,646 - 9,798,864 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl199,732,646 - 9,797,224 (+)EnsemblGRCr8
mRatBN7.2199,726,595 - 9,791,111 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,726,595 - 9,791,173 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx199,691,498 - 9,755,704 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01910,458,328 - 10,522,528 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0199,744,658 - 9,808,868 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01910,142,440 - 10,206,618 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1910,142,496 - 10,206,681 (+)Ensemblrn6Rnor6.0
Rnor_5.01910,126,285 - 10,190,852 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41910,186,416 - 10,257,296 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera199,619,420 - 9,683,573 (+)NCBICelera
RGSC_v3.11910,191,241 - 10,262,122NCBI
Cytogenetic Map19p13NCBI
CNGB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381657,882,340 - 57,971,128 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1657,882,340 - 57,971,128 (-)Ensemblhg38GRCh38
GRCh371657,916,244 - 58,005,032 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361656,475,206 - 56,562,513 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341656,475,003 - 56,562,497NCBI
Celera1642,413,576 - 42,502,338 (-)NCBICelera
Cytogenetic Map16q21NCBI
HuRef1643,783,333 - 43,871,939 (-)NCBIHuRef
CHM1_11659,323,315 - 59,412,065 (-)NCBICHM1_1
T2T-CHM13v2.01663,677,581 - 63,766,382 (-)NCBIT2T-CHM13v2.0
Cngb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39895,965,671 - 96,033,213 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl895,965,673 - 96,033,213 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38895,239,043 - 95,306,585 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl895,239,045 - 95,306,585 (-)Ensemblmm10GRCm38
MGSCv37897,814,493 - 97,830,485 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera899,610,443 - 99,627,497 (-)NCBICelera
Cytogenetic Map8C5NCBI
cM Map847.12NCBI
Cngb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,468,211 - 15,546,304 (-)Ensembl
ChiLan1.0NW_00495543315,467,042 - 15,556,471 (-)NCBIChiLan1.0ChiLan1.0
CNGB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21867,350,552 - 67,447,462 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11673,271,449 - 73,368,404 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01638,160,056 - 38,249,474 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11657,290,276 - 57,379,282 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1657,292,093 - 57,375,460 (-)EnsemblpanPan2panpan1.1
CNGB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,574,552 - 58,641,631 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,574,552 - 58,640,812 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha255,204,187 - 55,268,847 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0259,113,127 - 59,180,268 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl259,113,127 - 59,180,264 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1255,944,477 - 56,009,276 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0256,951,994 - 57,016,919 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0257,845,272 - 57,909,956 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cngb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934949,681,069 - 49,746,175 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364759,844,438 - 9,908,009 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNGB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1619,752,734 - 19,865,830 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2617,783,799 - 17,840,139 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNGB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1543,814,500 - 43,903,323 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604732,300,772 - 32,364,172 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cngb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474628,198,324 - 28,268,280 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cngb1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1172,105,576 - 2,166,481 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cngb1
444 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:79
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000060351
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131969901Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124694445Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127361636Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
PMC26527P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2199,758,010 - 9,758,216 (+)MAPPERmRatBN7.2
Rnor_6.01910,173,739 - 10,173,944NCBIRnor6.0
Rnor_6.01910,958,680 - 10,958,885NCBIRnor6.0
Rnor_5.01910,942,666 - 10,942,871UniSTSRnor5.0
Rnor_5.01910,157,245 - 10,157,450UniSTSRnor5.0
RGSC_v3.41910,223,978 - 10,224,183UniSTSRGSC3.4
Celera199,650,538 - 9,650,743UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map19p13UniSTS
RH138953  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2199,758,568 - 9,758,699 (+)MAPPERmRatBN7.2
Rnor_6.01910,959,238 - 10,959,368NCBIRnor6.0
Rnor_6.01910,174,297 - 10,174,427NCBIRnor6.0
Rnor_5.01910,157,803 - 10,157,933UniSTSRnor5.0
Rnor_5.01910,943,224 - 10,943,354UniSTSRnor5.0
RGSC_v3.41910,224,536 - 10,224,666UniSTSRGSC3.4
Celera199,651,096 - 9,651,226UniSTS
RH 3.4 Map1994.41UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map19p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
13 6 58 151 58 57 28 62 28 6 268 153 11 127 72 87 29 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000060351   ⟹   ENSRNOP00000063522
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,726,595 - 9,791,111 (+)Ensembl
Rnor_6.0 Ensembl1910,142,496 - 10,206,618 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000085440   ⟹   ENSRNOP00000073715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl199,754,956 - 9,797,224 (+)Ensembl
mRatBN7.2 Ensembl199,752,037 - 9,791,173 (+)Ensembl
Rnor_6.0 Ensembl1910,167,797 - 10,206,681 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088645   ⟹   ENSRNOP00000070248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,726,595 - 9,743,747 (+)Ensembl
Rnor_6.0 Ensembl1910,142,496 - 10,159,487 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109711   ⟹   ENSRNOP00000079558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl199,732,646 - 9,797,161 (+)Ensembl
mRatBN7.2 Ensembl199,726,595 - 9,791,111 (+)Ensembl
RefSeq Acc Id: NM_001389260   ⟹   NP_001376189
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,732,646 - 9,749,798 (+)NCBI
mRatBN7.2199,726,595 - 9,743,747 (+)NCBI
RefSeq Acc Id: NM_031809   ⟹   NP_113997
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,732,646 - 9,797,161 (+)NCBI
mRatBN7.2199,726,595 - 9,791,111 (+)NCBI
Rnor_6.01910,142,496 - 10,206,618 (+)NCBI
Rnor_5.01910,126,285 - 10,190,852 (+)NCBI
RGSC_v3.41910,186,416 - 10,257,296 (+)RGD
Celera199,619,420 - 9,683,573 (+)RGD
Sequence:
RefSeq Acc Id: XM_063278317   ⟹   XP_063134387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,762,063 - 9,798,864 (+)NCBI
RefSeq Acc Id: NP_113997   ⟸   NM_031809
- Peptide Label: isoform 1
- UniProtKB: O35788 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073715   ⟸   ENSRNOT00000085440
Ensembl Acc Id: ENSRNOP00000063522   ⟸   ENSRNOT00000060351
Ensembl Acc Id: ENSRNOP00000070248   ⟸   ENSRNOT00000088645
RefSeq Acc Id: NP_001376189   ⟸   NM_001389260
- Peptide Label: isoform 2
- UniProtKB: O55150 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079558   ⟸   ENSRNOT00000109711
RefSeq Acc Id: XP_063134387   ⟸   XM_063278317
- Peptide Label: isoform X1
- UniProtKB: A6JY21 (UniProtKB/TrEMBL)
Protein Domains
Cyclic nucleotide-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LQB8-F1-model_v2 AlphaFold F1LQB8 1-1338 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621809 AgrOrtholog
BioCyc Gene G2FUF-6527 BioCyc
Ensembl Genes ENSRNOG00000031773 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000060351.4 UniProtKB/Swiss-Prot
  ENSRNOT00000085440 ENTREZGENE
  ENSRNOT00000085440.2 UniProtKB/Swiss-Prot
  ENSRNOT00000088645.2 UniProtKB/Swiss-Prot
  ENSRNOT00000109711 ENTREZGENE
  ENSRNOT00000109711.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot
  Helix hairpin bin UniProtKB/Swiss-Prot
  Jelly Rolls UniProtKB/Swiss-Prot
InterPro CNG_Cation_Channel UniProtKB/Swiss-Prot
  cNMP-bd_CS UniProtKB/Swiss-Prot
  cNMP-bd_dom UniProtKB/Swiss-Prot
  cNMP-bd_dom_sf UniProtKB/Swiss-Prot
  RmlC-like_jellyroll UniProtKB/Swiss-Prot
NCBI Gene 83686 ENTREZGENE
PANTHER CYCLIC NUCLEOTIDE-GATED CATION CHANNEL BETA-1 UniProtKB/Swiss-Prot
  CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A UniProtKB/Swiss-Prot
Pfam cNMP_binding UniProtKB/Swiss-Prot
PhenoGen Cngb1 PhenoGen
PROSITE CNMP_BINDING_1 UniProtKB/Swiss-Prot
  CNMP_BINDING_2 UniProtKB/Swiss-Prot
  CNMP_BINDING_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000031773 RatGTEx
SMART cNMP UniProtKB/Swiss-Prot
Superfamily-SCOP cAMP-binding domain-like UniProtKB/Swiss-Prot
  Voltage-gated potassium channels UniProtKB/Swiss-Prot
UniProt A0A8I5ZN27 ENTREZGENE
  A6JY21 ENTREZGENE, UniProtKB/TrEMBL
  CNGB1_RAT UniProtKB/Swiss-Prot
  O35788 ENTREZGENE, UniProtKB/TrEMBL
  O55150 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A0G2JXF2 UniProtKB/Swiss-Prot
  A0A0G2K685 UniProtKB/Swiss-Prot
  F1LQB8 UniProtKB/Swiss-Prot
  O55157 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-02 Cngb1  cyclic nucleotide gated channel subunit beta 1  Cngb1  cyclic nucleotide gated channel beta 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-02-23 Cngb1  cyclic nucleotide gated channel beta 1  Gm1959_predicted  gene model 1959, (NCBI) (predicted)  Data merged from RGD:1307574 737654 APPROVED
2005-01-20 Cngb1  cyclic nucleotide gated channel beta 1    cyclic nucleotide-gated channel beta subunit 1  Name updated 1299863 APPROVED
2005-01-12 Gm1959_predicted  gene model 1959, (NCBI) (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 Cngb1  cyclic nucleotide-gated channel beta subunit 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_transcript has two alternative splicing forms, beta1a and beta1b 632392