Eloc (elongin C) - Rat Genome Database

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Gene: Eloc (elongin C) Rattus norvegicus
Analyze
Symbol: Eloc (Ensembl: LOC134482331)
Name: elongin C (Ensembl:elongin-C-like)
RGD ID: 620658
Description: Predicted to enable protein-macromolecule adaptor activity and transcription corepressor binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Involved in positive regulation of transcription elongation by RNA polymerase II. Part of VCB complex. Orthologous to human ELOC (elongin C); PARTICIPATES IN hypoxia inducible factor pathway; renal cell carcinoma pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; aconitine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: elongation factor SIII p15 subunit; elongin 15 kDa subunit; elongin-C; MGC72822; RNA polymerase II transcription factor SIII subunit C; SIII p15; stromal membrane-associated protein SMAP1B homolog; Tceb1; transcription elongation factor B (SIII), polypeptide 1; transcription elongation factor B polypeptide 1; transcription elongation factor B subunit 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Eloc-ps4  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr857,444,769 - 7,461,187 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2025,752,857 - 25,753,279 (+)EnsemblGRCr8
mRatBN7.252,661,527 - 2,677,893 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2025,754,169 - 25,754,577 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl52,661,724 - 2,677,890 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx54,780,099 - 4,796,466 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.056,418,969 - 6,435,336 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.056,117,553 - 6,133,943 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.052,042,991 - 2,059,357 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl52,042,991 - 2,059,351 (+)Ensemblrn6Rnor6.0
Rnor_5.052,044,009 - 2,060,375 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.451,961,106 - 1,966,991 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera52,283,738 - 2,300,104 (+)NCBICelera
RGSC_v3.151,960,610 - 1,975,903 (-)NCBI
Cytogenetic Map5q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
aconitine  (EXP)
acrolein  (ISO)
actinomycin D  (ISO)
alpha-pinene  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
dibutyl phthalate  (EXP,ISO)
dinophysistoxin 1  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
eugenol  (EXP)
finasteride  (EXP)
flutamide  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methidathion  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
Nutlin-3  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulindac  (EXP)
T-2 toxin  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
tolcapone  (EXP)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. RNA polymerase II transcription factor SIII. I. Identification, purification, and properties. Bradsher JN, etal., J Biol Chem 1993 Dec 5;268(34):25587-93.
2. Molecular cloning of an essential subunit of RNA polymerase II elongation factor SIII. Garrett KP, etal., Proc Natl Acad Sci U S A 1994 Jun 7;91(12):5237-41.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Kamura T, etal., Science. 1999 Apr 23;284(5414):657-61.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Regulation of oxygen homeostasis by hypoxia-inducible factor 1. Semenza GL Physiology (Bethesda). 2009 Apr;24:97-106.
Additional References at PubMed
PMID:8889548   PMID:9341197   PMID:10224134   PMID:11384984   PMID:12477932   PMID:15489334   PMID:16498413   PMID:17110338   PMID:19037258  


Genomics

Comparative Map Data
Eloc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr857,444,769 - 7,461,187 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2025,752,857 - 25,753,279 (+)EnsemblGRCr8
mRatBN7.252,661,527 - 2,677,893 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2025,754,169 - 25,754,577 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl52,661,724 - 2,677,890 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx54,780,099 - 4,796,466 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.056,418,969 - 6,435,336 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.056,117,553 - 6,133,943 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.052,042,991 - 2,059,357 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl52,042,991 - 2,059,351 (+)Ensemblrn6Rnor6.0
Rnor_5.052,044,009 - 2,060,375 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.451,961,106 - 1,966,991 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera52,283,738 - 2,300,104 (+)NCBICelera
RGSC_v3.151,960,610 - 1,975,903 (-)NCBI
Cytogenetic Map5q11NCBI
ELOC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38873,945,119 - 73,972,287 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl873,939,169 - 73,972,307 (-)Ensemblhg38GRCh38
GRCh37874,857,354 - 74,884,522 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36875,021,188 - 75,046,900 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34875,021,187 - 75,046,900NCBI
Celera870,856,322 - 70,882,037 (-)NCBICelera
Cytogenetic Map8q21.11NCBI
HuRef870,348,271 - 70,375,431 (-)NCBIHuRef
CHM1_1874,909,297 - 74,936,449 (-)NCBICHM1_1
T2T-CHM13v2.0874,374,361 - 74,401,537 (-)NCBIT2T-CHM13v2.0
Eloc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39116,711,949 - 16,727,652 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl116,711,949 - 16,727,266 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38116,641,725 - 16,657,428 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl116,641,725 - 16,657,042 (-)Ensemblmm10GRCm38
MGSCv37116,632,846 - 16,646,946 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36116,627,050 - 16,642,079 (-)NCBIMGSCv36mm8
Celera116,573,213 - 16,588,707 (-)NCBICelera
Cytogenetic Map1A3NCBI
cM Map15.1NCBI
Eloc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554446,400,832 - 6,415,881 (+)Ensembl
ChiLan1.0NW_0049554446,400,721 - 6,415,881 (+)NCBIChiLan1.0ChiLan1.0
ELOC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2789,688,699 - 89,715,685 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1865,316,706 - 65,343,144 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0870,479,805 - 70,506,142 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1872,125,388 - 72,151,118 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl872,121,035 - 72,151,085 (-)EnsemblpanPan2panpan1.1
ELOC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12922,452,254 - 22,476,523 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2922,453,544 - 22,476,429 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2922,717,298 - 22,741,493 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02922,562,889 - 22,587,095 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2922,560,200 - 22,587,014 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12922,621,622 - 22,646,088 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02922,657,010 - 22,681,258 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02922,940,162 - 22,964,613 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Eloc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530356,818,579 - 56,842,488 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366482,604,283 - 2,630,035 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366482,606,075 - 2,629,997 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELOC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl461,971,426 - 61,990,151 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1461,971,103 - 61,989,392 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2467,676,834 - 67,695,098 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ELOC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1869,546,943 - 69,572,694 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl869,545,965 - 69,560,268 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603971,799,030 - 71,824,504 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eloc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474417,270,476 - 17,299,029 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474417,270,861 - 17,299,541 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Eloc
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11136,157,707 - 136,174,245 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Eloc
126 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:55
Count of miRNA genes:51
Interacting mature miRNAs:53
Transcripts:ENSRNOT00000050236
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312562Pur18Proteinuria QTL 182.60.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)5692228237468560Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
61462Niddm10Non-insulin dependent diabetes mellitus QTL 103.90.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)519895442Rat
631551Vetf1Vascular elastic tissue fragility QTL 150.0001aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)5706553510687501Rat

Markers in Region
RH135267  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.252,677,654 - 2,677,865 (+)MAPPERmRatBN7.2
Rnor_6.052,059,119 - 2,059,329NCBIRnor6.0
Rnor_5.052,060,137 - 2,060,347UniSTSRnor5.0
RGSC_v3.451,959,594 - 1,959,804UniSTSRGSC3.4
Celera52,299,866 - 2,300,076UniSTS
Cytogenetic Map5q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001270561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001430040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001430041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001430042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_022593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI555412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK355540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM093546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM101371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM110992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L29259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000050236   ⟹   ENSRNOP00000067410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl52,669,795 - 2,677,890 (+)Ensembl
Rnor_6.0 Ensembl52,042,991 - 2,059,351 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082813   ⟹   ENSRNOP00000071456
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl52,043,583 - 2,059,351 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090313   ⟹   ENSRNOP00000069739
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl52,661,724 - 2,677,890 (+)Ensembl
Rnor_6.0 Ensembl52,043,155 - 2,059,351 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000140131   ⟹   ENSRNOP00000101569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl57,445,018 - 7,464,128 (+)Ensembl
RefSeq Acc Id: NM_001270561   ⟹   NP_001257490
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr857,445,413 - 7,461,187 (+)NCBI
mRatBN7.252,662,119 - 2,677,893 (+)NCBI
Rnor_6.052,043,583 - 2,059,357 (+)NCBI
Rnor_5.052,044,009 - 2,060,375 (+)NCBI
Celera52,284,330 - 2,300,104 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270562   ⟹   NP_001257491
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr857,444,985 - 7,461,187 (+)NCBI
mRatBN7.252,661,691 - 2,677,893 (+)NCBI
Rnor_6.052,043,155 - 2,059,357 (+)NCBI
Rnor_5.052,044,009 - 2,060,375 (+)NCBI
Celera52,283,902 - 2,300,104 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270563   ⟹   NP_001257492
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr857,444,985 - 7,461,187 (+)NCBI
mRatBN7.252,661,691 - 2,677,893 (+)NCBI
Rnor_6.052,043,155 - 2,059,357 (+)NCBI
Rnor_5.052,044,009 - 2,060,375 (+)NCBI
Celera52,283,902 - 2,300,104 (+)NCBI
Sequence:
RefSeq Acc Id: NM_022593   ⟹   NP_072115
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr857,444,821 - 7,461,187 (+)NCBI
mRatBN7.252,661,527 - 2,677,893 (+)NCBI
Rnor_6.052,042,991 - 2,059,357 (+)NCBI
Rnor_5.052,044,009 - 2,060,375 (+)NCBI
RGSC_v3.451,961,106 - 1,966,991 (-)RGD
Celera52,283,738 - 2,300,104 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006237724   ⟹   XP_006237786
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr857,444,769 - 7,459,665 (+)NCBI
mRatBN7.252,661,563 - 2,676,857 (+)NCBI
Rnor_6.052,043,069 - 2,058,321 (+)NCBI
Rnor_5.052,044,009 - 2,060,375 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039110711   ⟹   XP_038966639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr857,445,068 - 7,459,665 (+)NCBI
mRatBN7.252,662,494 - 2,676,857 (+)NCBI
RefSeq Acc Id: NP_072115   ⟸   NM_022593
- UniProtKB: P83941 (UniProtKB/Swiss-Prot),   A6JFA3 (UniProtKB/TrEMBL),   A0A096MIY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257491   ⟸   NM_001270562
- UniProtKB: P83941 (UniProtKB/Swiss-Prot),   A6JFA3 (UniProtKB/TrEMBL),   A0A096MIY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257492   ⟸   NM_001270563
- UniProtKB: P83941 (UniProtKB/Swiss-Prot),   A6JFA3 (UniProtKB/TrEMBL),   A0A096MIY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257490   ⟸   NM_001270561
- UniProtKB: P83941 (UniProtKB/Swiss-Prot),   A6JFA3 (UniProtKB/TrEMBL),   A0A096MIY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237786   ⟸   XM_006237724
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000071456   ⟸   ENSRNOT00000082813
Ensembl Acc Id: ENSRNOP00000069739   ⟸   ENSRNOT00000090313
Ensembl Acc Id: ENSRNOP00000067410   ⟸   ENSRNOT00000050236
RefSeq Acc Id: XP_038966639   ⟸   XM_039110711
- Peptide Label: isoform X1
- UniProtKB: P83941 (UniProtKB/Swiss-Prot),   A6JFA3 (UniProtKB/TrEMBL),   A0A096MIY6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101569   ⟸   ENSRNOT00000140131
Protein Domains
SKP1 component POZ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P83941-F1-model_v2 AlphaFold P83941 1-112 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693523
Promoter ID:EPDNEW_R4047
Type:multiple initiation site
Name:Eloc_1
Description:elongin C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4048  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.052,043,020 - 2,043,080EPDNEW
RGD ID:13693524
Promoter ID:EPDNEW_R4048
Type:initiation region
Name:Eloc_2
Description:elongin C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4047  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.052,043,182 - 2,043,242EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620658 AgrOrtholog
BioCyc Gene G2FUF-42312 BioCyc
Ensembl Genes ENSRNOG00000031730 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000051063 Ensembl
  ENSRNOG00000076409 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000090313.2 UniProtKB/Swiss-Prot
  ENSRNOT00000140131 ENTREZGENE
Gene3D-CATH Potassium Channel Kv1.1, Chain A UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6918038 IMAGE-MGC_LOAD
InterPro ELC1 UniProtKB/Swiss-Prot
  SKP1-like UniProtKB/Swiss-Prot
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot
  Skp1_comp_POZ UniProtKB/Swiss-Prot
KEGG Report rno:64525 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72822 IMAGE-MGC_LOAD
NCBI Gene 64525 ENTREZGENE
PANTHER PTHR20648 UniProtKB/Swiss-Prot
Pfam Skp1_POZ UniProtKB/Swiss-Prot
PhenoGen Eloc PhenoGen
RatGTEx ENSRNOG00000031730 RatGTEx
  ENSRNOG00000051063 RatGTEx
  ENSRNOG00000076409 RatGTEx
SMART Skp1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54695 UniProtKB/Swiss-Prot
UniProt A0A096MIY6 ENTREZGENE, UniProtKB/TrEMBL
  A6JFA3 ENTREZGENE, UniProtKB/TrEMBL
  ELOC_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q63182 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-11-09 Eloc  elongin C  Tceb1  transcription elongation factor B subunit 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-16 Tceb1  transcription elongation factor B subunit 1  Tceb1  transcription elongation factor B (SIII), polypeptide 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Tceb1  transcription elongation factor B (SIII), polypeptide 1    elongation factor SIII p15 subunit  Name updated 1299863 APPROVED
2002-08-07 Tceb1  elongation factor SIII p15 subunit      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction combines with 110 kDa and 18 kDa subunit to form the transcription factor B (SIII) complex 730012
gene_process important for trancriptional regulation with RNA polymerase II 730008
gene_protein predicted protein has 112 aa residues and masses 12.4 kDa 730008