Cyth3 (cytohesin 3) - Rat Genome Database

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Gene: Cyth3 (cytohesin 3) Rattus norvegicus
Analyze
Symbol: Cyth3
Name: cytohesin 3
RGD ID: 620399
Description: Predicted to enable guanyl-nucleotide exchange factor activity and phosphatidylinositol-3,4,5-trisphosphate binding activity. Predicted to be involved in Golgi vesicle transport. Predicted to act upstream of or within establishment of epithelial cell polarity and positive regulation of cell adhesion. Predicted to be located in several cellular components, including adherens junction; bicellular tight junction; and ruffle. Orthologous to human CYTH3 (cytohesin 3); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cytohesin-3; MGC124579; PH, SEC7 and coiled-coil domain-containing protein 3; pleckstrin homology, Sec7 and coiled-coil domains 3; pleckstrin homology, Sec7 and coiled/coil domains 3; Pscd3; rSec7-3; Sec7; SEC7 homolog C; Sec7C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,953,781 - 16,076,584 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1215,953,791 - 16,047,506 (-)EnsemblGRCr8
mRatBN7.21210,840,137 - 10,933,792 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,840,157 - 10,933,812 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1211,647,392 - 11,740,819 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01212,270,686 - 12,364,108 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,294,673 - 11,388,443 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01212,877,559 - 12,907,771 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1212,877,559 - 12,945,192 (-)Ensemblrn6Rnor6.0
Rnor_5.01214,921,905 - 14,953,442 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41211,169,420 - 11,198,144 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1212,636,946 - 12,730,083 (-)NCBICelera
RGSC_v3.11211,201,327 - 11,228,073 (-)NCBI
Cytogenetic Map12p11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Rat homologues of yeast sec7p. Telemenakis I, etal., Eur J Cell Biol. 1997 Oct;74(2):143-9.
Additional References at PubMed
PMID:9072969   PMID:9707577   PMID:9742223   PMID:10605025   PMID:11001876   PMID:11445584   PMID:12477932   PMID:17398095   PMID:20080746   PMID:23940353  


Genomics

Comparative Map Data
Cyth3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,953,781 - 16,076,584 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1215,953,791 - 16,047,506 (-)EnsemblGRCr8
mRatBN7.21210,840,137 - 10,933,792 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,840,157 - 10,933,812 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1211,647,392 - 11,740,819 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01212,270,686 - 12,364,108 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,294,673 - 11,388,443 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01212,877,559 - 12,907,771 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1212,877,559 - 12,945,192 (-)Ensemblrn6Rnor6.0
Rnor_5.01214,921,905 - 14,953,442 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41211,169,420 - 11,198,144 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1212,636,946 - 12,730,083 (-)NCBICelera
RGSC_v3.11211,201,327 - 11,228,073 (-)NCBI
Cytogenetic Map12p11NCBI
CYTH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3876,161,779 - 6,272,624 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl76,161,776 - 6,272,650 (-)Ensemblhg38GRCh38
GRCh3776,201,410 - 6,312,255 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3676,167,935 - 6,278,767 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3475,974,652 - 6,085,482NCBI
Celera76,422,869 - 6,533,702 (+)NCBICelera
Cytogenetic Map7p22.1NCBI
HuRef76,073,515 - 6,102,268 (-)NCBIHuRef
CHM1_176,201,010 - 6,311,828 (-)NCBICHM1_1
T2T-CHM13v2.076,281,155 - 6,392,015 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v276,247,766 - 6,358,597 (-)NCBI
Cyth3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395143,608,202 - 143,696,005 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5143,608,202 - 143,696,005 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385143,622,447 - 143,710,250 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5143,622,447 - 143,710,250 (+)Ensemblmm10GRCm38
MGSCv375144,383,316 - 144,471,119 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365143,878,153 - 143,965,865 (+)NCBIMGSCv36mm8
Celera5140,664,821 - 140,752,813 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map582.36NCBI
Cyth3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546013,462,505 - 13,492,767 (+)Ensembl
ChiLan1.0NW_00495546013,439,634 - 13,492,767 (+)NCBIChiLan1.0ChiLan1.0
CYTH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2611,398,092 - 11,511,949 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1759,722,808 - 59,836,661 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v077,170,064 - 7,283,000 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.176,357,978 - 6,386,725 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl76,357,978 - 6,386,756 (-)EnsemblpanPan2panpan1.1
CYTH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1611,554,922 - 11,653,201 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl611,556,511 - 11,645,086 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha613,180,741 - 13,285,865 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0611,555,477 - 11,660,618 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl611,555,477 - 11,645,797 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1611,431,973 - 11,537,027 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0611,411,206 - 11,516,184 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0611,637,860 - 11,743,271 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cyth3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344139,636,669 - 139,727,627 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936750283,583 - 308,604 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936750283,994 - 308,591 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYTH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl34,900,570 - 5,002,194 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.134,900,575 - 5,002,201 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CYTH3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12815,366,238 - 15,479,781 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2815,369,402 - 15,479,540 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666102604,064 - 717,566 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cyth3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474031,071,193 - 31,191,264 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474031,071,169 - 31,191,318 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cyth3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1169,410,814 - 9,502,253 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cyth3
1037 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:244
Count of miRNA genes:164
Interacting mature miRNAs:197
Transcripts:ENSRNOT00000001412
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12592191825247790Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
1357337Gluco3Glucose level QTL 30.0004adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)12116966671Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)121186960016966542Rat
61334Gluco17Glucose level QTL 176.3adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)12116966671Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)121223300030490641Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12124849755Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat

Markers in Region
D12Got20  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21210,912,410 - 10,912,644 (+)MAPPERmRatBN7.2
Rnor_6.01212,952,147 - 12,952,380NCBIRnor6.0
Rnor_5.01214,997,656 - 14,997,889UniSTSRnor5.0
RGSC_v3.41211,243,844 - 11,244,078RGDRGSC3.4
RGSC_v3.41211,243,845 - 11,244,078UniSTSRGSC3.4
Celera1212,708,694 - 12,708,923UniSTS
RGSC_v3.11211,273,773 - 11,274,006RGD
RH 3.4 Map12145.92UniSTS
RH 3.4 Map12145.92RGD
RH 2.0 Map12129.6RGD
Cytogenetic Map12p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000001412   ⟹   ENSRNOP00000001412
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1215,953,791 - 16,047,428 (-)Ensembl
mRatBN7.2 Ensembl1210,840,157 - 10,933,812 (-)Ensembl
Rnor_6.0 Ensembl1212,877,559 - 12,907,771 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082529   ⟹   ENSRNOP00000075144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1212,879,668 - 12,945,192 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000128862   ⟹   ENSRNOP00000103429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1215,953,791 - 16,018,501 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000129902   ⟹   ENSRNOP00000109621
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1215,953,791 - 16,047,506 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000132895   ⟹   ENSRNOP00000112358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1215,953,791 - 15,979,518 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000167846   ⟹   ENSRNOP00000100089
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1215,953,791 - 15,979,465 (-)Ensembl
RefSeq Acc Id: NM_053912   ⟹   NP_446364
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,953,781 - 16,047,428 (-)NCBI
mRatBN7.21210,840,137 - 10,933,792 (-)NCBI
Rnor_6.01212,877,559 - 12,907,771 (-)NCBI
Rnor_5.01214,921,905 - 14,953,442 (-)NCBI
RGSC_v3.41211,169,420 - 11,198,144 (-)RGD
Celera1212,636,946 - 12,730,083 (-)RGD
Sequence:
RefSeq Acc Id: XM_039089024   ⟹   XP_038944952
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,953,781 - 16,033,195 (-)NCBI
mRatBN7.21210,840,137 - 10,905,299 (-)NCBI
RefSeq Acc Id: XM_039089028   ⟹   XP_038944956
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,953,781 - 16,034,957 (-)NCBI
mRatBN7.21210,840,137 - 10,921,269 (-)NCBI
RefSeq Acc Id: XM_063271012   ⟹   XP_063127082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,953,781 - 16,047,493 (-)NCBI
RefSeq Acc Id: XM_063271013   ⟹   XP_063127083
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81215,953,781 - 16,076,584 (-)NCBI
RefSeq Acc Id: NP_446364   ⟸   NM_053912
- UniProtKB: P97696 (UniProtKB/Swiss-Prot),   Q3T1J6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075144   ⟸   ENSRNOT00000082529
Ensembl Acc Id: ENSRNOP00000001412   ⟸   ENSRNOT00000001412
RefSeq Acc Id: XP_038944956   ⟸   XM_039089028
- Peptide Label: isoform X3
- UniProtKB: P97696 (UniProtKB/Swiss-Prot),   A6K1K3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944952   ⟸   XM_039089024
- Peptide Label: isoform X1
- UniProtKB: P97696 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063127083   ⟸   XM_063271013
- Peptide Label: isoform X3
- UniProtKB: P97696 (UniProtKB/Swiss-Prot),   A6K1K3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127082   ⟸   XM_063271012
- Peptide Label: isoform X2
- UniProtKB: P97696 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000109621   ⟸   ENSRNOT00000129902
Ensembl Acc Id: ENSRNOP00000100089   ⟸   ENSRNOT00000167846
Ensembl Acc Id: ENSRNOP00000103429   ⟸   ENSRNOT00000128862
Ensembl Acc Id: ENSRNOP00000112358   ⟸   ENSRNOT00000132895
Protein Domains
PH   SEC7

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97696-F1-model_v2 AlphaFold P97696 1-400 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620399 AgrOrtholog
BioCyc Gene G2FUF-20010 BioCyc
Ensembl Genes ENSRNOG00000001065 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000001412 ENTREZGENE
  ENSRNOT00000128862 ENTREZGENE
  ENSRNOT00000129902 ENTREZGENE
  ENSRNOT00000132895 ENTREZGENE
Gene3D-CATH 1.10.1000.11 UniProtKB/Swiss-Prot
  1.10.220.20 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7929513 IMAGE-MGC_LOAD
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot
  PH_domain UniProtKB/Swiss-Prot
  Sec7_C_sf UniProtKB/Swiss-Prot
  Sec7_dom UniProtKB/Swiss-Prot
  Sec7_dom_sf UniProtKB/Swiss-Prot
MGC_CLONE MGC:124579 IMAGE-MGC_LOAD
NCBI Gene 116693 ENTREZGENE
PANTHER CYTOHESIN-3 UniProtKB/Swiss-Prot
  GUANYL-NUCLEOTIDE EXCHANGE FACTOR UniProtKB/Swiss-Prot
Pfam PF00169 UniProtKB/Swiss-Prot
  Sec7 UniProtKB/Swiss-Prot
PhenoGen Cyth3 PhenoGen
PROSITE PH_DOMAIN UniProtKB/Swiss-Prot
  SEC7 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001065 RatGTEx
SMART Sec7 UniProtKB/Swiss-Prot
  SM00233 UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF48425 UniProtKB/Swiss-Prot
UniProt A0ABK0L621_RAT UniProtKB/TrEMBL
  A0ABK0LMY0_RAT UniProtKB/TrEMBL
  A0ABK0LQI0_RAT UniProtKB/TrEMBL
  A0ABK0M3L1_RAT UniProtKB/TrEMBL
  A6K1K3 ENTREZGENE, UniProtKB/TrEMBL
  CYH3_RAT UniProtKB/Swiss-Prot
  F1LQP0_RAT UniProtKB/TrEMBL
  P97696 ENTREZGENE
  Q3T1J6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-04 Cyth3  cytohesin 3  Pscd3  pleckstrin homology, Sec7 and coiled-coil domains 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Pscd3  pleckstrin homology, Sec7 and coiled-coil domains 3  Pscd3  pleckstrin homology, Sec7 and coiled/coil domains 3  Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_homology has homology to S. cerevisiae sec7p 729512