CYTH3 (cytohesin 3) - Rat Genome Database

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Keyword

Gene: CYTH3 (cytohesin 3) Homo sapiens

Symbol:

CYTH3

Name:

cytohesin 3

Description:

This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

ARF nucleotide-binding site opener 3; ARNO3; cytohesin-3; general receptor of phosphoinositides 1; GRP1; OTTHUMP00000115876; PH, SEC7 and coiled-coil domain-containing protein 3; pleckstrin homology, Sec7 and coiled-coil domains 3; pleckstrin homology, Sec7 and coiled/coil domains 3; PSCD3

Orthologs:

Mus musculus : Cyth3 (cytohesin 3) MGI
Rattus norvegicus : Cyth3 (cytohesin 3)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	7	6,173,460 - 6,284,548	-	NCBI
Human Alternate Assembly CRA_TCAGchr7v2	7	6,247,766 - 6,358,597	-	NCBI
Human Genome Assembly HuRef	7	6,073,515 - 6,102,268	-	NCBI
Human Genome Assembly GRCh37	7	6,201,410 - 6,312,242	-	NCBI
Human Genome Assembly Build 36	7	6,167,935 - 6,278,767	-	NCBI
Human Cytogenetic Map	7	p22.1		NCBI
Human Genome Assembly	7	5,974,652 - 6,085,482		NCBI