Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rbbp7 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Rbbp7 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RBBP7 mRNA | CTD | PMID:22206623 | Rbbp7 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Rbbp7 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RBBP7 mRNA | CTD | PMID:17942748 | Rbbp7 | Rat | 17beta-estradiol | increases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Estradiol results in increased expression of RBBP7 mRNA | CTD | PMID:16514628 | Rbbp7 | Rat | 17beta-estradiol | multiple interactions | ISO | RBBP7 (Homo sapiens) | 6480464 | Estradiol promotes the reaction [RBBP7 protein binds to ESR1 protein] | CTD | PMID:27156127 | Rbbp7 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Rbbp7 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RBBP7 mRNA | CTD | PMID:17949056 | Rbbp7 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RBBP7 mRNA | CTD | PMID:32109520 and PMID:34747641 | Rbbp7 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rbbp7 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RBBP7 mRNA | CTD | PMID:21570461 | Rbbp7 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Rbbp7 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RBBP7 mRNA | CTD | PMID:17942748 | Rbbp7 | Rat | 2,4,6-tribromophenol | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Rbbp7 | Rat | 2-amino-14,16-dimethyloctadecan-3-ol | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | 2-amino-14 and 16-dimethyloctadecan-3-ol results in decreased expression of RBBP7 protein | CTD | PMID:32044396 | Rbbp7 | Rat | 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine | decreases expression | ISO | Rbbp7 (Mus musculus) | 6480464 | Puromycin Aminonucleoside results in decreased expression of RBBP7 protein | CTD | PMID:15798086 | Rbbp7 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of RBBP7 protein | CTD | PMID:31675489 | Rbbp7 | Rat | 3-methylcholanthrene | multiple interactions | ISO | RBBP7 (Homo sapiens) | 6480464 | Methylcholanthrene promotes the reaction [AHR protein binds to RBBP7 promoter] | CTD | PMID:20348232 | Rbbp7 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Rbbp7 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of RBBP7 mRNA | CTD | PMID:18648102 | Rbbp7 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of RBBP7 mRNA | CTD | PMID:36041667 | Rbbp7 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of RBBP7 protein | CTD | PMID:34186270 | Rbbp7 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Rbbp7 (Mus musculus) | 6480464 | Fenretinide results in increased expression of RBBP7 mRNA | CTD | PMID:28973697 | Rbbp7 | Rat | afimoxifene | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | afimoxifene results in decreased expression of RBBP7 mRNA | CTD | PMID:16514628 | Rbbp7 | Rat | all-trans-retinoic acid | decreases expression | ISO | Rbbp7 (Mus musculus) | 6480464 | Tretinoin results in decreased expression of RBBP7 mRNA | CTD | PMID:16604517 | Rbbp7 | Rat | antirheumatic drug | increases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of RBBP7 mRNA | CTD | PMID:24449571 | Rbbp7 | Rat | aristolochic acid A | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of RBBP7 mRNA | CTD | PMID:33212167 | Rbbp7 | Rat | Aroclor 1254 | decreases expression | ISO | Rbbp7 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of RBBP7 mRNA | CTD | PMID:23650126 | Rbbp7 | Rat | benzo[a]pyrene | affects expression | ISO | Rbbp7 (Mus musculus) | 6480464 | Benzo(a)pyrene affects the expression of RBBP7 mRNA | CTD | PMID:22342234 | Rbbp7 | Rat | benzo[a]pyrene | increases methylation | ISO | RBBP7 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of RBBP7 promoter | CTD | PMID:27901495 | Rbbp7 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RBBP7 mRNA | CTD | PMID:25181051 | Rbbp7 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of RBBP7 mRNA | CTD | PMID:36041667 | Rbbp7 | Rat | bisphenol A | increases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of RBBP7 protein | CTD | PMID:34186270 | Rbbp7 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of RBBP7 mRNA | CTD | PMID:34947998 | Rbbp7 | Rat | bisphenol A | affects expression | ISO | RBBP7 (Homo sapiens) | 6480464 | bisphenol A affects the expression of RBBP7 mRNA | CTD | PMID:30903817 | Rbbp7 | Rat | bisphenol A | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of RBBP7 mRNA | CTD | PMID:29275510 | Rbbp7 | Rat | bisphenol A | decreases methylation | ISO | Rbbp7 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of RBBP7 promoter | CTD | PMID:27312807 | Rbbp7 | Rat | bisphenol F | increases expression | ISO | Rbbp7 (Mus musculus) | 6480464 | bisphenol F results in increased expression of RBBP7 mRNA | CTD | PMID:38685157 | Rbbp7 | Rat | bisphenol F | increases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of RBBP7 protein | CTD | PMID:34186270 | Rbbp7 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of RBBP7 mRNA | CTD | PMID:36041667 | Rbbp7 | Rat | cadmium atom | multiple interactions | ISO | Rbbp7 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RBBP7 mRNA | CTD | PMID:37325564 | Rbbp7 | Rat | cadmium dichloride | multiple interactions | ISO | Rbbp7 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RBBP7 mRNA | CTD | PMID:37325564 | Rbbp7 | Rat | caffeine | increases phosphorylation | ISO | RBBP7 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of RBBP7 protein | CTD | PMID:35688186 | Rbbp7 | Rat | carbamazepine | affects expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of RBBP7 mRNA | CTD | PMID:25979313 | Rbbp7 | Rat | cisplatin | increases phosphorylation | ISO | Rbbp7 (Mus musculus) | 6480464 | Cisplatin results in increased phosphorylation of RBBP7 protein | CTD | PMID:22006019 | Rbbp7 | Rat | cobalt dichloride | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of RBBP7 mRNA | CTD | PMID:19320972 and PMID:19376846 | Rbbp7 | Rat | copper atom | multiple interactions | ISO | RBBP7 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of RBBP7 mRNA | CTD | PMID:20971185 | Rbbp7 | Rat | copper(0) | multiple interactions | ISO | RBBP7 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of RBBP7 mRNA | CTD | PMID:20971185 | Rbbp7 | Rat | copper(II) sulfate | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of RBBP7 mRNA | CTD | PMID:19549813 | Rbbp7 | Rat | cortisol | affects response to substance | ISO | RBBP7 (Homo sapiens) | 6480464 | RBBP7 protein affects the susceptibility to Hydrocortisone | CTD | PMID:12767060 | Rbbp7 | Rat | cyclosporin A | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of RBBP7 mRNA | CTD | PMID:25562108 | Rbbp7 | Rat | decabromodiphenyl ether | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of RBBP7 protein | CTD | PMID:31675489 | Rbbp7 | Rat | dibenzofurans | decreases expression | ISO | Rbbp7 (Mus musculus) | 6480464 | Dibenzofurans results in decreased expression of RBBP7 mRNA | CTD | PMID:34254344 | Rbbp7 | Rat | dicrotophos | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of RBBP7 mRNA | CTD | PMID:28302478 | Rbbp7 | Rat | enzyme inhibitor | multiple interactions | ISO | RBBP7 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of RBBP7 protein | CTD | PMID:23301498 | Rbbp7 | Rat | ethanol | affects splicing | ISO | Rbbp7 (Mus musculus) | 6480464 | Ethanol affects the splicing of RBBP7 mRNA | CTD | PMID:30319688 | Rbbp7 | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of RBBP7 mRNA | CTD | PMID:24136188 | Rbbp7 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of RBBP7 mRNA | CTD | PMID:24136188 | Rbbp7 | Rat | folic acid | multiple interactions | ISO | Rbbp7 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RBBP7 mRNA | CTD | PMID:22206623 | Rbbp7 | Rat | FR900359 | affects phosphorylation | ISO | RBBP7 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of RBBP7 protein | CTD | PMID:37730182 | Rbbp7 | Rat | fulvestrant | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | fulvestrant results in decreased expression of RBBP7 mRNA | CTD | PMID:16514628 | Rbbp7 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of RBBP7 mRNA | CTD | PMID:25539665 | Rbbp7 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of RBBP7 mRNA | CTD | PMID:22061828 | Rbbp7 | Rat | ivermectin | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of RBBP7 protein | CTD | PMID:32959892 | Rbbp7 | Rat | leflunomide | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of RBBP7 mRNA | CTD | PMID:28988120 | Rbbp7 | Rat | methoxyacetic acid | multiple interactions | ISO | RBBP7 (Homo sapiens) | 6480464 | methoxyacetic acid promotes the reaction [Promegestone results in increased expression of RBBP7 mRNA] | CTD | PMID:15103026 | Rbbp7 | Rat | mitomycin C | increases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Mitomycin results in increased expression of RBBP7 mRNA | CTD | PMID:12760830 | Rbbp7 | Rat | mono(2-ethylhexyl) phthalate | affects expression | ISO | Rbbp7 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate affects the expression of RBBP7 mRNA | CTD | PMID:21195148 | Rbbp7 | Rat | Monobutylphthalate | affects expression | ISO | Rbbp7 (Mus musculus) | 6480464 | monobutyl phthalate affects the expression of RBBP7 mRNA | CTD | PMID:21195148 | Rbbp7 | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of RBBP7 mRNA | CTD | PMID:24136188 | Rbbp7 | Rat | nickel subsulfide | increases expression | EXP | | 6480464 | nickel subsulfide results in increased expression of RBBP7 mRNA | CTD | PMID:21086188 | Rbbp7 | Rat | ozone | increases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Ozone results in increased expression of RBBP7 mRNA | CTD | PMID:23033980 | Rbbp7 | Rat | ozone | multiple interactions | ISO | Rbbp7 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of RBBP7 mRNA | CTD | PMID:34911549 | Rbbp7 | Rat | paracetamol | affects expression | ISO | Rbbp7 (Mus musculus) | 6480464 | Acetaminophen affects the expression of RBBP7 mRNA | CTD | PMID:17562736 | Rbbp7 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of RBBP7 mRNA | CTD | PMID:33387578 | Rbbp7 | Rat | paracetamol | increases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of RBBP7 mRNA | CTD | PMID:22230336 | Rbbp7 | Rat | paracetamol | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of RBBP7 mRNA | CTD | PMID:21420995 | Rbbp7 | Rat | perfluorooctanoic acid | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of RBBP7 protein | CTD | PMID:26879310 | Rbbp7 | Rat | phenobarbital | affects expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of RBBP7 mRNA | CTD | PMID:19159669 | Rbbp7 | Rat | pirinixic acid | increases expression | ISO | Rbbp7 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of RBBP7 mRNA | CTD | PMID:23811191 | Rbbp7 | Rat | promegestone | increases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Promegestone results in increased expression of RBBP7 mRNA | CTD | PMID:15103026 | Rbbp7 | Rat | promegestone | multiple interactions | ISO | RBBP7 (Homo sapiens) | 6480464 | methoxyacetic acid promotes the reaction [Promegestone results in increased expression of RBBP7 mRNA] | CTD | PMID:15103026 | Rbbp7 | Rat | raloxifene | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Raloxifene Hydrochloride results in decreased expression of RBBP7 mRNA | CTD | PMID:16514628 | Rbbp7 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of RBBP7 protein | CTD | PMID:35544339 | Rbbp7 | Rat | SB 431542 | multiple interactions | ISO | RBBP7 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of RBBP7 protein | CTD | PMID:37664457 | Rbbp7 | Rat | sodium arsenite | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of RBBP7 mRNA | CTD | PMID:38568856 | Rbbp7 | Rat | sodium dichromate | increases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | sodium bichromate results in increased expression of RBBP7 mRNA | CTD | PMID:12760830 | Rbbp7 | Rat | sulindac | increases expression | EXP | | 6480464 | Sulindac results in increased expression of RBBP7 mRNA | CTD | PMID:24136188 | Rbbp7 | Rat | temozolomide | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of RBBP7 mRNA | CTD | PMID:31758290 | Rbbp7 | Rat | testosterone | increases expression | ISO | Rbbp7 (Mus musculus) | 6480464 | Testosterone results in increased expression of RBBP7 mRNA | CTD | PMID:19693291 | Rbbp7 | Rat | tetrachloromethane | increases expression | ISO | Rbbp7 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of RBBP7 mRNA | CTD | PMID:31919559 | Rbbp7 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of RBBP7 mRNA | CTD | PMID:23411599 | Rbbp7 | Rat | thiram | decreases expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Thiram results in decreased expression of RBBP7 mRNA | CTD | PMID:38568856 | Rbbp7 | Rat | titanium dioxide | increases methylation | ISO | Rbbp7 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of RBBP7 gene and titanium dioxide results in increased methylation of RBBP7 promoter | CTD | PMID:35295148 | Rbbp7 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of RBBP7 mRNA | CTD | PMID:33387578 | Rbbp7 | Rat | triptonide | increases expression | ISO | Rbbp7 (Mus musculus) | 6480464 | triptonide results in increased expression of RBBP7 mRNA | CTD | PMID:33045310 | Rbbp7 | Rat | uranium atom | affects expression | ISO | RBBP7 (Homo sapiens) | 6480464 | Uranium affects the expression of RBBP7 mRNA | CTD | PMID:15672453 | |