Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Arid4b | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Arid4b (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of ARID4B mRNA | CTD | PMID:22206623 | Arid4b | Rat | 17beta-estradiol | affects expression | ISO | ARID4B (Homo sapiens) | 6480464 | Estradiol affects the expression of ARID4B mRNA | CTD | PMID:22574217 | Arid4b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Arid4b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ARID4B promoter] | CTD | PMID:19654925 | Arid4b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Arid4b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARID4B mRNA | CTD | PMID:21570461 | Arid4b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ARID4B mRNA | CTD | PMID:21215274|PMID:33387578 | Arid4b | Rat | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | EXP | | 6480464 | 2,3,7,8-tetrachlorodibenzofuran results in increased expression of ARID4B mRNA | CTD | PMID:32109520 | Arid4b | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ARID4B mRNA | CTD | PMID:30851411 | Arid4b | Rat | 2-methylcholine | affects expression | ISO | ARID4B (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of ARID4B mRNA | CTD | PMID:21179406 | Arid4b | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Arid4b (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of ARID4B mRNA | CTD | PMID:26251327 | Arid4b | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | ARID4B (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of ARID4B gene | CTD | PMID:31601247 | Arid4b | Rat | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | multiple interactions | ISO | ARID4B (Homo sapiens) | 6480464 | [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of ARID4B mRNA | CTD | PMID:20146248 | Arid4b | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ARID4B mRNA | CTD | PMID:30047161 | Arid4b | Rat | acrolein | multiple interactions | ISO | ARID4B (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... | CTD | PMID:32699268|PMID:32845096 | Arid4b | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of ARID4B mRNA | CTD | PMID:28959563 | Arid4b | Rat | acrylamide | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Acrylamide results in increased expression of ARID4B mRNA | CTD | PMID:32763439 | Arid4b | Rat | aflatoxin B1 | increases expression | ISO | Arid4b (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of ARID4B mRNA | CTD | PMID:19770486 | Arid4b | Rat | all-trans-retinoic acid | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ARID4B mRNA | CTD | PMID:33167477 | Arid4b | Rat | alpha-pinene | multiple interactions | ISO | ARID4B (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... | CTD | PMID:32699268 | Arid4b | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of ARID4B mRNA | CTD | PMID:30047161 | Arid4b | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of ARID4B mRNA | CTD | PMID:16483693 | Arid4b | Rat | arsenous acid | increases response to substance | ISO | ARID4B (Homo sapiens) | 6480464 | ARID4B protein results in increased susceptibility to Arsenic Trioxide | CTD | PMID:20707922 | Arid4b | Rat | benzo[a]pyrene | multiple interactions | ISO | ARID4B (Homo sapiens) | 6480464 | [Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of ARID4B mRNA | CTD | PMID:20146248 | Arid4b | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ARID4B (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ARID4B mRNA | CTD | PMID:19150397|PMID:20018196 | Arid4b | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Arid4b (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of ARID4B mRNA | CTD | PMID:33754040 | Arid4b | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ARID4B mRNA | CTD | PMID:25181051 | Arid4b | Rat | bisphenol A | affects methylation | ISO | ARID4B (Homo sapiens) | 6480464 | bisphenol A affects the methylation of ARID4B gene | CTD | PMID:31601247 | Arid4b | Rat | bisphenol A | multiple interactions | ISO | ARID4B (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ARID4B gene | CTD | PMID:31601247 | Arid4b | Rat | bisphenol A | increases expression | ISO | Arid4b (Mus musculus) | 6480464 | bisphenol A results in increased expression of ARID4B mRNA | CTD | PMID:33221593 | Arid4b | Rat | caffeine | decreases phosphorylation | ISO | ARID4B (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of ARID4B protein | CTD | PMID:35688186 | Arid4b | Rat | captan | decreases expression | ISO | Arid4b (Mus musculus) | 6480464 | Captan results in decreased expression of ARID4B mRNA | CTD | PMID:31558096 | Arid4b | Rat | carbon nanotube | decreases expression | ISO | Arid4b (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of ARID4B mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681|PMID:31978390 | Arid4b | Rat | CGP 52608 | multiple interactions | ISO | ARID4B (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ARID4B gene] | CTD | PMID:28238834 | Arid4b | Rat | cobalt dichloride | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of ARID4B mRNA | CTD | PMID:19376846 | Arid4b | Rat | copper(II) sulfate | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of ARID4B mRNA | CTD | PMID:19549813 | Arid4b | Rat | coumarin | decreases phosphorylation | ISO | ARID4B (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of ARID4B protein | CTD | PMID:35688186 | Arid4b | Rat | coumestrol | decreases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of ARID4B mRNA | CTD | PMID:19167446 | Arid4b | Rat | cyclosporin A | decreases expression | ISO | Arid4b (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of ARID4B mRNA | CTD | PMID:19770486 | Arid4b | Rat | cyclosporin A | decreases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ARID4B mRNA | CTD | PMID:25562108 | Arid4b | Rat | diarsenic trioxide | increases response to substance | ISO | ARID4B (Homo sapiens) | 6480464 | ARID4B protein results in increased susceptibility to Arsenic Trioxide | CTD | PMID:20707922 | Arid4b | Rat | Dibutyl phosphate | affects expression | ISO | ARID4B (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of ARID4B mRNA | CTD | PMID:37042841 | Arid4b | Rat | folpet | increases expression | ISO | Arid4b (Mus musculus) | 6480464 | folpet results in increased expression of ARID4B mRNA | CTD | PMID:31558096 | Arid4b | Rat | formaldehyde | decreases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of ARID4B mRNA | CTD | PMID:20655997 | Arid4b | Rat | FR900359 | affects phosphorylation | ISO | ARID4B (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of ARID4B protein | CTD | PMID:37730182 | Arid4b | Rat | fulvestrant | multiple interactions | ISO | ARID4B (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ARID4B gene | CTD | PMID:31601247 | Arid4b | Rat | glyphosate | increases expression | EXP | | 6480464 | Glyphosate results in increased expression of ARID4B mRNA | CTD | PMID:26302742 | Arid4b | Rat | hydrogen peroxide | affects expression | ISO | ARID4B (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of ARID4B mRNA | CTD | PMID:21179406 | Arid4b | Rat | isoprenaline | increases expression | ISO | Arid4b (Mus musculus) | 6480464 | Isoproterenol results in increased expression of ARID4B mRNA | CTD | PMID:20003209 | Arid4b | Rat | leflunomide | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | leflunomide results in increased expression of ARID4B mRNA | CTD | PMID:28988120 | Arid4b | Rat | leflunomide | decreases expression | ISO | Arid4b (Mus musculus) | 6480464 | leflunomide results in decreased expression of ARID4B mRNA | CTD | PMID:19751817 | Arid4b | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of ARID4B mRNA | CTD | PMID:30047161 | Arid4b | Rat | methyl methanesulfonate | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of ARID4B mRNA | CTD | PMID:23649840 | Arid4b | Rat | N-methyl-4-phenylpyridinium | decreases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of ARID4B mRNA | CTD | PMID:28801915 | Arid4b | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ARID4B mRNA | CTD | PMID:25729387 | Arid4b | Rat | ozone | multiple interactions | ISO | ARID4B (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ... | CTD | PMID:32699268|PMID:32845096 | Arid4b | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ARID4B mRNA | CTD | PMID:33387578 | Arid4b | Rat | phenobarbital | decreases expression | ISO | Arid4b (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of ARID4B mRNA | CTD | PMID:23091169 | Arid4b | Rat | propiconazole | decreases expression | EXP | | 6480464 | propiconazole results in decreased expression of ARID4B mRNA | CTD | PMID:30047161 | Arid4b | Rat | rac-lactic acid | decreases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ARID4B mRNA | CTD | PMID:30851411 | Arid4b | Rat | silver atom | affects expression | ISO | Arid4b (Mus musculus) | 6480464 | Silver affects the expression of ARID4B mRNA | CTD | PMID:27131904 | Arid4b | Rat | silver atom | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Silver results in increased expression of ARID4B mRNA | CTD | PMID:26014281 | Arid4b | Rat | silver(0) | affects expression | ISO | Arid4b (Mus musculus) | 6480464 | Silver affects the expression of ARID4B mRNA | CTD | PMID:27131904 | Arid4b | Rat | silver(0) | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Silver results in increased expression of ARID4B mRNA | CTD | PMID:26014281 | Arid4b | Rat | sodium arsenate | increases expression | ISO | Arid4b (Mus musculus) | 6480464 | sodium arsenate results in increased expression of ARID4B mRNA | CTD | PMID:21795629 | Arid4b | Rat | sodium arsenite | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ARID4B mRNA | CTD | PMID:17879257|PMID:38568856 | Arid4b | Rat | sodium arsenite | decreases expression | ISO | Arid4b (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of ARID4B mRNA | CTD | PMID:36209798 | Arid4b | Rat | thapsigargin | increases expression | ISO | Arid4b (Mus musculus) | 6480464 | Thapsigargin results in increased expression of ARID4B protein | CTD | PMID:24648495 | Arid4b | Rat | thiram | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Thiram results in increased expression of ARID4B mRNA | CTD | PMID:38568856 | Arid4b | Rat | titanium dioxide | decreases methylation | ISO | Arid4b (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of ARID4B gene | CTD | PMID:35295148 | Arid4b | Rat | titanium dioxide | increases methylation | ISO | Arid4b (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of ARID4B gene | CTD | PMID:35295148 | Arid4b | Rat | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of ARID4B mRNA | CTD | PMID:25729387 | Arid4b | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ARID4B mRNA | CTD | PMID:25729387 | Arid4b | Rat | torcetrapib | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | torcetrapib results in increased expression of ARID4B mRNA | CTD | PMID:23228038 | Arid4b | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of ARID4B mRNA | CTD | PMID:33387578 | Arid4b | Rat | triptonide | increases expression | ISO | Arid4b (Mus musculus) | 6480464 | triptonide results in increased expression of ARID4B mRNA | CTD | PMID:33045310 | Arid4b | Rat | triticonazole | decreases expression | EXP | | 6480464 | triticonazole results in decreased expression of ARID4B mRNA | CTD | PMID:36084822 | Arid4b | Rat | tungsten | decreases expression | ISO | Arid4b (Mus musculus) | 6480464 | Tungsten results in decreased expression of ARID4B mRNA | CTD | PMID:30912803 | Arid4b | Rat | urethane | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Urethane results in increased expression of ARID4B mRNA | CTD | PMID:28818685 | Arid4b | Rat | valproic acid | decreases methylation | ISO | ARID4B (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of ARID4B gene | CTD | PMID:29154799 | Arid4b | Rat | valproic acid | affects expression | ISO | ARID4B (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ARID4B mRNA | CTD | PMID:25979313 | Arid4b | Rat | valproic acid | decreases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ARID4B mRNA | CTD | PMID:23179753|PMID:28001369 | Arid4b | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of ARID4B mRNA | CTD | PMID:19015723 | Arid4b | Rat | vincristine | increases expression | ISO | ARID4B (Homo sapiens) | 6480464 | Vincristine results in increased expression of ARID4B mRNA | CTD | PMID:23649840 | Arid4b | Rat | vorinostat | decreases expression | ISO | ARID4B (Homo sapiens) | 6480464 | vorinostat results in decreased expression of ARID4B mRNA | CTD | PMID:27188386 | Arid4b | Rat | zinc atom | multiple interactions | ISO | ARID4B (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of ARID4B mRNA | CTD | PMID:18593933 | Arid4b | Rat | zinc(0) | multiple interactions | ISO | ARID4B (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of ARID4B mRNA | CTD | PMID:18593933 | | 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