Rps2 (ribosomal protein S2) - Rat Genome Database

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Gene: Rps2 (ribosomal protein S2) Rattus norvegicus
Analyze
Symbol: Rps2
Name: ribosomal protein S2
RGD ID: 619887
Description: A structural constituent of ribosome. Involved in formation of translation preinitiation complex; response to ethanol; and ribosomal small subunit assembly. Part of cytosolic small ribosomal subunit. Orthologous to human RPS2 (ribosomal protein S2); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 40S ribosomal protein S2; Rps2r1; small ribosomal subunit protein uS5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rps2-ps1   Rps2-ps10   Rps2-ps15   Rps2-ps2   Rps2-ps3   Rps2-ps37   Rps2-ps4   Rps2-ps44   Rps2-ps6   Rps2-ps7  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,251,841 - 14,253,697 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1014,251,380 - 14,253,695 (+)EnsemblGRCr8
mRatBN7.21013,747,316 - 13,749,165 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,747,301 - 13,749,163 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1018,494,095 - 18,495,957 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,982,955 - 17,984,817 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,482,151 - 13,484,013 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,088,171 - 14,090,020 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,088,319 - 14,089,979 (+)Ensemblrn6Rnor6.0
Rnor_5.01013,903,899 - 13,905,748 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41013,975,350 - 13,977,199 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1013,427,034 - 13,428,883 (+)NCBICelera
RGSC_v3.11013,975,494 - 13,977,163 (+)NCBI
Cytogenetic Map10q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-trinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acrolein  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenic trichloride  (ISO)
arsenite(3-)  (ISO)
astaxanthin  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
caffeine  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
clofibric acid  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
CU-O LINKAGE  (ISO)
D-glucose  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
diisononyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
fenpyroximate  (ISO)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (EXP)
furfural  (ISO)
gentamycin  (EXP)
glucose  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lead nitrate  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
Mesaconitine  (EXP)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
Nutlin-3  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
PhIP  (EXP)
pyrimidifen  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium fluoride  (ISO)
Soman  (EXP)
tamibarotene  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
tungsten  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2. The isolation of eukaryotic ribosomal proteins. The purification and characterization of the 40 S ribosomal subunit proteins S2, S3, S4, S5, S6, S7, S8, S9, S13, S23/S24, S27, and S28. Collatz E, etal., J Biol Chem. 1976 Aug 10;251(15):4666-72.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Effect of ethanol on hepatic ribosomal proteins and mRNA. Haviryaji KS, etal., Mol Cell Biochem. 1992 Oct 7;115(2):143-7.
6. Immunoelectron microscopic studies on the location of ribosomal proteins on the surface of the 40S ribosomal subunit from rat liver. Lutsch G, etal., Eur J Cell Biol. 1990 Feb;51(1):140-50.
7. Ribosomal proteins S2, S6, S10, S14, S15 and S25 are localized on the surface of mammalian 40 S subunits and stabilize their conformation. A study with immobilized trypsin. Marion MJ and Marion C, FEBS Lett. 1988 May 23;232(2):281-5.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Localization of rat liver ribosomal protein S2 and its involvement in initiation factor eIF-2 binding to the 40 S ribosomal subunit. Noll F, etal., FEBS Lett. 1978 Mar 1;87(1):129-31.
10. Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits. O'Donohue MF, etal., J Cell Biol. 2010 Sep 6;190(5):853-66. doi: 10.1083/jcb.201005117.
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Physical mapping and structural analysis of new gene families RT1.S and Rps2r in the grc region of the rat major histocompatibility complex. Salgar SK, etal., Immunogenetics 1997;45(6):353-64.
14. Primary structure of rat ribosomal protein S2. A ribosomal protein with arginine-glycine tandem repeats and RGGF motifs that are associated with nucleolar localization and binding to ribonucleic acids. Suzuki K, etal., J Biol Chem 1991 Oct 25;266(30):20007-10.
Additional References at PubMed
PMID:8706699   PMID:8889548   PMID:9798653   PMID:12477932   PMID:15883184   PMID:16061210   PMID:16263090   PMID:16452087   PMID:16854843   PMID:18464793   PMID:18573314   PMID:19946888  
PMID:20458337   PMID:21423176   PMID:21584310   PMID:21630459   PMID:21700703   PMID:22658674   PMID:22681889   PMID:22871113   PMID:23376485   PMID:25468996   PMID:35352799  


Genomics

Comparative Map Data
Rps2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,251,841 - 14,253,697 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1014,251,380 - 14,253,695 (+)EnsemblGRCr8
mRatBN7.21013,747,316 - 13,749,165 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,747,301 - 13,749,163 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1018,494,095 - 18,495,957 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,982,955 - 17,984,817 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,482,151 - 13,484,013 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,088,171 - 14,090,020 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,088,319 - 14,089,979 (+)Ensemblrn6Rnor6.0
Rnor_5.01013,903,899 - 13,905,748 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41013,975,350 - 13,977,199 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1013,427,034 - 13,428,883 (+)NCBICelera
RGSC_v3.11013,975,494 - 13,977,163 (+)NCBI
Cytogenetic Map10q12NCBI
RPS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38161,962,058 - 1,964,826 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl161,962,050 - 1,965,510 (-)Ensemblhg38GRCh38
GRCh37162,012,059 - 2,014,827 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,952,063 - 1,954,828 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34161,952,062 - 1,954,630NCBI
Celera162,224,244 - 2,227,009 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef161,936,189 - 1,938,954 (-)NCBIHuRef
CHM1_1162,012,008 - 2,014,773 (-)NCBICHM1_1
T2T-CHM13v2.0161,982,017 - 1,984,785 (-)NCBIT2T-CHM13v2.0
Rps2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,939,037 - 24,940,901 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,937,090 - 24,940,903 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381724,718,121 - 24,721,927 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,718,116 - 24,721,929 (+)Ensemblmm10GRCm38
MGSCv371724,857,008 - 24,858,872 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361724,447,709 - 24,449,522 (+)NCBIMGSCv36mm8
Celera1725,243,190 - 25,245,054 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.51NCBI
Rps2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,304,548 - 15,306,551 (+)Ensembl
ChiLan1.0NW_00495544215,304,306 - 15,306,599 (+)NCBIChiLan1.0ChiLan1.0
RPS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,382,477 - 2,385,374 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,164,618 - 6,167,276 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016739,562 - 742,323 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,051,083 - 2,053,825 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,051,128 - 2,054,086 (-)EnsemblpanPan2panpan1.1
RPS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,966,830 - 38,968,743 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,206,543 - 40,208,435 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0639,283,871 - 39,285,763 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,283,855 - 39,285,508 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,960,646 - 38,962,538 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,932,954 - 38,934,846 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,411,841 - 39,413,733 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rps2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,636,052 - 104,637,992 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366942,070,509 - 2,073,408 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366942,071,295 - 2,073,409 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,001,326 - 40,003,107 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1339,996,179 - 40,003,110 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RPS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.151,859,411 - 1,862,322 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl51,859,454 - 1,862,305 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606829,205,593 - 29,217,053 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rps2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624913295,563 - 300,676 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624913295,554 - 297,588 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rps2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v192,006,441 - 2,008,186 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rps2
3 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:94
Count of miRNA genes:85
Interacting mature miRNAs:89
Transcripts:ENSRNOT00000019508
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat

Markers in Region
fb10e01.x1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2873,322,429 - 73,322,582 (+)MAPPERmRatBN7.2
mRatBN7.23110,790,675 - 110,790,836 (+)MAPPERmRatBN7.2
Rnor_6.03115,745,958 - 115,746,118NCBIRnor6.0
Rnor_6.0879,263,183 - 79,263,335NCBIRnor6.0
Rnor_5.0873,824,519 - 73,824,671UniSTSRnor5.0
Rnor_5.03122,283,995 - 122,284,155UniSTSRnor5.0
RGSC_v3.43110,651,043 - 110,651,203UniSTSRGSC3.4
RGSC_v3.4877,190,390 - 77,190,542UniSTSRGSC3.4
Celera868,427,361 - 68,427,513UniSTS
Celera3109,671,423 - 109,671,583UniSTS
Cytogenetic Map10q12UniSTS
Cytogenetic Map8q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC093937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC115181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI713815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB324420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD372915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U92696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U92697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U92698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U92699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U92700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000019508   ⟹   ENSRNOP00000019508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1014,251,803 - 14,253,695 (+)Ensembl
mRatBN7.2 Ensembl1013,747,301 - 13,749,163 (+)Ensembl
Rnor_6.0 Ensembl1014,088,319 - 14,089,979 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000162258   ⟹   ENSRNOP00000102464
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1014,251,380 - 14,253,695 (+)Ensembl
RefSeq Acc Id: NM_031838   ⟹   NP_114026
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,251,848 - 14,253,697 (+)NCBI
mRatBN7.21013,747,316 - 13,749,165 (+)NCBI
Rnor_6.01014,088,171 - 14,090,020 (+)NCBI
Rnor_5.01013,903,899 - 13,905,748 (+)NCBI
RGSC_v3.41013,975,350 - 13,977,199 (+)RGD
Celera1013,427,034 - 13,428,883 (+)RGD
Sequence:
RefSeq Acc Id: XM_063269975   ⟹   XP_063126045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,251,841 - 14,253,697 (+)NCBI
RefSeq Acc Id: NP_114026   ⟸   NM_031838
- UniProtKB: Q4G062 (UniProtKB/Swiss-Prot),   P27952 (UniProtKB/Swiss-Prot),   E9PU05 (UniProtKB/TrEMBL),   O55215 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019508   ⟸   ENSRNOT00000019508
RefSeq Acc Id: XP_063126045   ⟸   XM_063269975
- Peptide Label: isoform X1
- UniProtKB: Q4G062 (UniProtKB/Swiss-Prot),   P27952 (UniProtKB/Swiss-Prot),   E9PU05 (UniProtKB/TrEMBL),   O55215 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000102464   ⟸   ENSRNOT00000162258
Protein Domains
S5 DRBM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P27952-F1-model_v2 AlphaFold P27952 1-293 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619887 AgrOrtholog
BioCyc Gene G2FUF-25829 BioCyc
Ensembl Genes ENSRNOG00000014179 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000019508.7 UniProtKB/Swiss-Prot
  ENSRNOT00000162258 ENTREZGENE
Gene3D-CATH 3.30.160.20 UniProtKB/Swiss-Prot
  3.30.230.10 UniProtKB/Swiss-Prot
InterPro Ribosomal_S5 UniProtKB/Swiss-Prot
  Ribosomal_S5_C UniProtKB/Swiss-Prot
  Ribosomal_S5_D2-typ_fold UniProtKB/Swiss-Prot
  Ribosomal_S5_D2-typ_fold_subgr UniProtKB/Swiss-Prot
  Ribosomal_S5_euk/arc UniProtKB/Swiss-Prot
  Ribosomal_S5_N UniProtKB/Swiss-Prot
  Ribosomal_S5_N_CS UniProtKB/Swiss-Prot
KEGG Report rno:83789 UniProtKB/Swiss-Prot
NCBI Gene 83789 ENTREZGENE
PANTHER PTHR13718 UniProtKB/Swiss-Prot
  SMALL RIBOSOMAL SUBUNIT PROTEIN US5 UniProtKB/Swiss-Prot
Pfam Ribosomal_S5 UniProtKB/Swiss-Prot
  Ribosomal_S5_C UniProtKB/Swiss-Prot
PhenoGen Rps2 PhenoGen
PROSITE RIBOSOMAL_S5 UniProtKB/Swiss-Prot
  S5_DSRBD UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014179 RatGTEx
Superfamily-SCOP dsRNA-binding domain-like UniProtKB/Swiss-Prot
  SSF54211 UniProtKB/Swiss-Prot
UniProt E9PU05 ENTREZGENE
  O55215 ENTREZGENE, UniProtKB/TrEMBL
  P27952 ENTREZGENE
  Q4G062 ENTREZGENE
  RS2_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q4G062 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-02-24 Rps2  ribosomal protein S2  Rps2r1  Ribosomal protein S2  Data merged from RGD:3597 737654 APPROVED
2005-01-20 Rps2  ribosomal protein S2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Rps2  ribosomal protein S2      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Rps2r1  Ribosomal protein S2      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA detected in testis and thymus, but not in liver or spleen 1334504
gene_mapping Salgar et al map this and two pseudogenes to the growth and reproduction complex region of chromosome 20 1334504
gene_other genome contains 23-28 copies 634045
gene_process may be involved in binding of aminoacyl-tRNA to ribosomes and maintaining fidelity of translation 634045
gene_protein 293 amino acids and a molecular weight of 31,211 634045