UBLCP1 (ubiquitin like domain containing CTD phosphatase 1)

Gene: UBLCP1 (ubiquitin like domain containing CTD phosphatase 1) Homo sapiens

Analyze

Symbol:

UBLCP1

Name:

ubiquitin like domain containing CTD phosphatase 1

RGD ID:

1605293

HGNC Page

HGNC:28110

Description:

Enables proteasome regulatory particle binding activity and protein serine/threonine phosphatase activity. Involved in regulation of proteasome assembly. Located in nucleolus and nucleoplasm.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CPUB1; CTD phosphatase-like with ubiquitin domain 1; CTD-like phosphatase domain-containing protein; FLJ25267; MGC10067; nuclear proteasome inhibitor UBLCP1; ubiquitin-like domain containing CTD phosphatase 1; ubiquitin-like domain-containing CTD phosphatase 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	159,263,290 - 159,286,036 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	159,263,290 - 159,286,036 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	158,690,298 - 158,713,044 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	158,622,876 - 158,645,617 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	154,720,940 - 154,743,899 (+)	NCBI		Celera
Cytogenetic Map	5	q33.3	NCBI
HuRef	5	153,784,215 - 153,807,159 (+)	NCBI		HuRef
CHM1_1	5	158,122,533 - 158,145,488 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	159,791,779 - 159,814,534 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Breast Neoplasms (EXP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (ISO)

2,6-dinitrotoluene (ISO)

2-hydroxypropanoic acid (EXP)

3-chloropropane-1,2-diol (ISO)

aflatoxin M1 (EXP)

aristolochic acid A (EXP)

arsane (EXP)

arsenic atom (EXP)

atrazine (EXP)

benzo[a]pyrene (EXP,ISO)

benzo[a]pyrene diol epoxide I (EXP)

bisphenol A (ISO)

Bisphenol B (EXP)

bisphenol F (EXP)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (EXP)

clorgyline (EXP)

cobalt dichloride (EXP)

copper(II) sulfate (EXP)

dicrotophos (EXP)

doxorubicin (EXP)

enzyme inhibitor (EXP)

ethanol (ISO)

fenthion (ISO)

flutamide (ISO)

folic acid (ISO)

indometacin (EXP)

ivermectin (EXP)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (EXP,ISO)

pirinixic acid (ISO)

rac-lactic acid (EXP)

resveratrol (EXP)

SB 431542 (EXP)

sunitinib (EXP)

tungsten (ISO)

valproic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

regulation of proteasome assembly (IMP)

Cellular Component

nucleolus (IDA)

nucleoplasm (IDA)

nucleus (IBA,IDA,IEA)

Molecular Function

metal ion binding (IEA)

myosin phosphatase activity (IEA)

phosphoprotein phosphatase activity (IEA)

proteasome regulatory particle binding (IPI)

protein binding (IPI)

protein serine/threonine phosphatase activity (IBA,IDA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:12477932	PMID:14702039	PMID:15489334	PMID:15883030	PMID:16189514	PMID:16344560	PMID:18029348	PMID:21873635	PMID:21949367	PMID:22939629	PMID:23667555
PMID:24811749	PMID:25416956	PMID:26186194	PMID:26344197	PMID:27034005	PMID:27114451	PMID:27880917	PMID:28292943	PMID:28514442	PMID:28539385	PMID:28581483	PMID:28611215
PMID:30021884	PMID:31659016	PMID:31843888	PMID:32296183	PMID:32416067	PMID:32628020	PMID:32687490	PMID:32723828	PMID:33545068	PMID:33961781	PMID:34761751	PMID:35256949
PMID:35439318	PMID:35509820	PMID:35831314	PMID:35944360	PMID:36215168	PMID:36724073	PMID:37827155	PMID:38113892	PMID:38129378

Genomics

Comparative Map Data

UBLCP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	159,263,290 - 159,286,036 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	159,263,290 - 159,286,036 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	158,690,298 - 158,713,044 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	158,622,876 - 158,645,617 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	154,720,940 - 154,743,899 (+)	NCBI		Celera
Cytogenetic Map	5	q33.3	NCBI
HuRef	5	153,784,215 - 153,807,159 (+)	NCBI		HuRef
CHM1_1	5	158,122,533 - 158,145,488 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	159,791,779 - 159,814,534 (+)	NCBI		T2T-CHM13v2.0

Ublcp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	44,345,398 - 44,361,540 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	44,345,398 - 44,361,325 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	44,454,571 - 44,470,713 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	44,454,571 - 44,470,498 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	44,268,073 - 44,284,050 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	44,297,996 - 44,313,868 (-)	NCBI		MGSCv36	mm8
Celera	11	17,009,149 - 17,013,836 (-)	NCBI		Celera
Cytogenetic Map	11	B1.1	NCBI
cM Map	11	25.94	NCBI

Ublcp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	29,447,081 - 29,462,446 (-)	NCBI		GRCr8
mRatBN7.2	10	28,945,690 - 28,961,103 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	28,945,698 - 28,960,996 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	33,690,046 - 33,705,356 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	2,228,449 - 2,243,759 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	28,660,657 - 28,675,967 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	30,103,607 - 30,118,945 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	30,103,613 - 30,118,873 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	29,936,811 - 29,952,143 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	29,612,055 - 29,627,325 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	29,613,103 - 29,628,374 (-)	NCBI
Celera	10	28,424,577 - 28,439,847 (-)	NCBI		Celera
Cytogenetic Map	10	q21	NCBI

Ublcp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	13,259,328 - 13,279,574 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955408	13,259,328 - 13,279,509 (+)	NCBI	ChiLan1.0	ChiLan1.0

UBLCP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	154,449,198 - 154,472,275 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	152,588,746 - 152,611,827 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	154,655,018 - 154,677,794 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	161,271,839 - 161,294,639 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	161,271,844 - 161,294,643 (+)	Ensembl	panpan1.1		panPan2

UBLCP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	51,218,471 - 51,237,661 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	51,218,928 - 51,234,198 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	51,111,527 - 51,130,760 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	51,653,336 - 51,672,559 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	51,653,332 - 51,672,583 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	51,482,378 - 51,501,638 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	51,587,989 - 51,607,229 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	52,104,659 - 52,123,934 (-)	NCBI		UU_Cfam_GSD_1.0

Ublcp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	105,643,923 - 105,662,457 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936515	4,096,146 - 4,112,234 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936515	4,093,255 - 4,111,616 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UBLCP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	64,178,941 - 64,205,675 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	64,182,918 - 64,205,684 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	70,006,436 - 70,029,004 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UBLCP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	61,664,467 - 61,686,874 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	61,664,677 - 61,687,433 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	15,933,584 - 15,955,836 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ublcp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	30,179,102 - 30,201,768 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624733	30,166,045 - 30,202,081 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in UBLCP1
3 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 5q32-35.3(chr5:149714592-181272151)x3	copy number gain	See cases [RCV000051863]	Chr5:149714592..181272151 [GRCh38] Chr5:149094155..180699152 [GRCh37] Chr5:149074348..180631758 [NCBI36] Chr5:5q32-35.3	pathogenic
GRCh38/hg38 5q33.1-34(chr5:152761187-167248053)x1	copy number loss	See cases [RCV000052144]	Chr5:152761187..167248053 [GRCh38] Chr5:152140747..166675058 [GRCh37] Chr5:152120940..166607636 [NCBI36] Chr5:5q33.1-34	pathogenic
GRCh38/hg38 5q33.1-34(chr5:153195314-164014005)x1	copy number loss	See cases [RCV000052145]	Chr5:153195314..164014005 [GRCh38] Chr5:152574874..163441011 [GRCh37] Chr5:152555067..163373589 [NCBI36] Chr5:5q33.1-34	pathogenic
GRCh38/hg38 5q33.3-35.3(chr5:156825512-181269805)x3	copy number gain	See cases [RCV000133847]	Chr5:156825512..181269805 [GRCh38] Chr5:156252523..180696806 [GRCh37] Chr5:156185101..180629412 [NCBI36] Chr5:5q33.3-35.3	pathogenic
GRCh38/hg38 5q33.3-34(chr5:158941354-164386760)x1	copy number loss	See cases [RCV000138895]	Chr5:158941354..164386760 [GRCh38] Chr5:158368362..163813766 [GRCh37] Chr5:158300940..163746344 [NCBI36] Chr5:5q33.3-34	pathogenic
GRCh38/hg38 5q33.1-34(chr5:152443869-166104392)x1	copy number loss	See cases [RCV000138282]	Chr5:152443869..166104392 [GRCh38] Chr5:151823430..165531397 [GRCh37] Chr5:151803623..165463975 [NCBI36] Chr5:5q33.1-34	pathogenic
GRCh37/hg19 5q33.2-35.1(chr5:154886174-169757448)x1	copy number loss	See cases [RCV000240059]	Chr5:154886174..169757448 [GRCh37] Chr5:5q33.2-35.1	pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3	copy number gain	See cases [RCV000448245]	Chr5:106716357..180687338 [GRCh37] Chr5:5q21.3-35.3	pathogenic
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3	copy number gain	not provided [RCV000487658]	Chr5:94844077..178830410 [GRCh37] Chr5:5q15-35.3	likely benign
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)	copy number gain	See cases [RCV000510723]	Chr5:113577..180719789 [GRCh37] Chr5:5p15.33-q35.3	pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1	copy number loss	See cases [RCV000511978]	Chr5:17628741..176575720 [GRCh37] Chr5:5p15.1-q35.2	pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3	copy number gain	See cases [RCV000512039]	Chr5:113577..180719789 [GRCh37] Chr5:5p15.33-q35.3	pathogenic
GRCh37/hg19 5q33.2-35.3(chr5:155344802-180693344)x3	copy number gain	not provided [RCV000745284]	Chr5:155344802..180693344 [GRCh37] Chr5:5q33.2-35.3	pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3	copy number gain	not provided [RCV000744323]	Chr5:25328..180693344 [GRCh37] Chr5:5p15.33-q35.3	pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3	copy number gain	not provided [RCV000744317]	Chr5:13648..180905029 [GRCh37] Chr5:5p15.33-q35.3	pathogenic
GRCh37/hg19 5q33.3(chr5:158423338-159076314)x3	copy number gain	not provided [RCV000848661]	Chr5:158423338..159076314 [GRCh37] Chr5:5q33.3	uncertain significance
GRCh37/hg19 5q33.3-35.1(chr5:156597181-171166353)x3	copy number gain	not provided [RCV000845588]	Chr5:156597181..171166353 [GRCh37] Chr5:5q33.3-35.1	pathogenic
GRCh37/hg19 5q33.3-34(chr5:157801321-162780186)x1	copy number loss	not provided [RCV001005747]	Chr5:157801321..162780186 [GRCh37] Chr5:5q33.3-34	pathogenic
GRCh37/hg19 5q33.3-35.1(chr5:156347980-169959880)x1	copy number loss	not provided [RCV001005746]	Chr5:156347980..169959880 [GRCh37] Chr5:5q33.3-35.1	pathogenic
GRCh37/hg19 5q33.3-34(chr5:155970607-162450579)x1	copy number loss	not provided [RCV001825167]	Chr5:155970607..162450579 [GRCh37] Chr5:5q33.3-34	not provided
GRCh37/hg19 5q32-35.3(chr5:149010383-180719789)	copy number gain	Hunter-McAlpine craniosynostosis [RCV002280612]	Chr5:149010383..180719789 [GRCh37] Chr5:5q32-35.3	pathogenic
Single allele	duplication	not specified [RCV002286367]	Chr5:158887731..164722046 [GRCh38] Chr5:5q33.3-34	uncertain significance
GRCh37/hg19 5q33.1-35.2(chr5:150535183-172906793)x3	copy number gain	not provided [RCV002474507]	Chr5:150535183..172906793 [GRCh37] Chr5:5q33.1-35.2	pathogenic
GRCh37/hg19 5q33.3-34(chr5:156786013-162945369)x1	copy number loss	not provided [RCV002512289]	Chr5:156786013..162945369 [GRCh37] Chr5:5q33.3-34	likely pathogenic
NM_145049.5(UBLCP1):c.518C>T (p.Ala173Val)	single nucleotide variant	not specified [RCV004128036]	Chr5:159272092 [GRCh38] Chr5:158699100 [GRCh37] Chr5:5q33.3	uncertain significance
NM_145049.5(UBLCP1):c.913C>T (p.His305Tyr)	single nucleotide variant	not specified [RCV004180774]	Chr5:159283323 [GRCh38] Chr5:158710331 [GRCh37] Chr5:5q33.3	uncertain significance
NM_145049.5(UBLCP1):c.703A>G (p.Ile235Val)	single nucleotide variant	not specified [RCV004325229]	Chr5:159278256 [GRCh38] Chr5:158705264 [GRCh37] Chr5:5q33.3	uncertain significance
NM_145049.5(UBLCP1):c.142C>T (p.Leu48Phe)	single nucleotide variant	not specified [RCV004477000]	Chr5:159269057 [GRCh38] Chr5:158696065 [GRCh37] Chr5:5q33.3	uncertain significance
NM_145049.5(UBLCP1):c.233G>A (p.Arg78His)	single nucleotide variant	not specified [RCV004477001]	Chr5:159269986 [GRCh38] Chr5:158696994 [GRCh37] Chr5:5q33.3	uncertain significance
NM_145049.5(UBLCP1):c.401G>T (p.Arg134Met)	single nucleotide variant	not specified [RCV004477002]	Chr5:159270596 [GRCh38] Chr5:158697604 [GRCh37] Chr5:5q33.3	uncertain significance
NM_145049.5(UBLCP1):c.402G>T (p.Arg134Ser)	single nucleotide variant	not specified [RCV004477004]	Chr5:159270597 [GRCh38] Chr5:158697605 [GRCh37] Chr5:5q33.3	uncertain significance
NM_145049.5(UBLCP1):c.608C>A (p.Ala203Glu)	single nucleotide variant	not specified [RCV004477005]	Chr5:159275170 [GRCh38] Chr5:158702178 [GRCh37] Chr5:5q33.3	uncertain significance
NM_145049.5(UBLCP1):c.950G>T (p.Gly317Val)	single nucleotide variant	not specified [RCV004477006]	Chr5:159284924 [GRCh38] Chr5:158711932 [GRCh37] Chr5:5q33.3	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	498
Count of miRNA genes:	390
Interacting mature miRNAs:	427
Transcripts:	ENST00000296786, ENST00000519276, ENST00000521738
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

RH41101

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	7	83,840,084 - 83,840,315	UniSTS	GRCh37
GRCh37	5	158,712,786 - 158,713,017	UniSTS	GRCh37
Build 36	5	158,645,364 - 158,645,595	RGD	NCBI36
Celera	5	154,743,637 - 154,743,868	RGD
Celera	7	78,541,155 - 78,541,386	UniSTS
Cytogenetic Map	5	q33.3	UniSTS
HuRef	7	78,448,928 - 78,449,159	UniSTS
HuRef	5	153,806,897 - 153,807,128	UniSTS
CRA_TCAGchr7v2	7	83,171,845 - 83,172,076	UniSTS

RH93697

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	7	83,840,194 - 83,840,320	UniSTS	GRCh37
GRCh37	5	158,712,781 - 158,712,907	UniSTS	GRCh37
Build 36	5	158,645,359 - 158,645,485	RGD	NCBI36
Celera	5	154,743,632 - 154,743,758	RGD
Celera	7	78,541,265 - 78,541,391	UniSTS
Cytogenetic Map	5	q33.3	UniSTS
HuRef	7	78,449,038 - 78,449,164	UniSTS
HuRef	5	153,806,892 - 153,807,018	UniSTS
CRA_TCAGchr7v2	7	83,171,955 - 83,172,081	UniSTS
GeneMap99-GB4 RH Map	5	591.55	UniSTS

MGC10067__7655

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	5	158,712,320 - 158,713,205	UniSTS	GRCh37
Build 36	5	158,644,898 - 158,645,783	RGD	NCBI36
Celera	5	154,743,171 - 154,744,056	RGD
HuRef	5	153,806,431 - 153,807,316	UniSTS

RH36361

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	5	158,712,277 - 158,712,376	UniSTS	GRCh37
Build 36	5	158,644,855 - 158,644,954	RGD	NCBI36
Celera	5	154,743,128 - 154,743,227	RGD
Cytogenetic Map	5	q33.3	UniSTS
HuRef	5	153,806,388 - 153,806,487	UniSTS
GeneMap99-GB4 RH Map	5	591.55	UniSTS
NCBI RH Map	5	884.1	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

visual system

adipose tissue

appendage

entire extraembryonic component

pharyngeal arch

High

Medium

2339

2180

1478

386

1671

234

3897

1424

3289

352

1439

1598

168

1200

2351

Low

100

811

248

238

280

231

460

773

445

437

Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_145049	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC011418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK057996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY444562	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BM676716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BM677370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA930581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000296786 ⟹ ENSP00000296786

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	5	159,263,290 - 159,286,036 (+)	Ensembl

RefSeq Acc Id:

ENST00000519276

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	5	159,274,542 - 159,286,036 (+)	Ensembl

RefSeq Acc Id:

ENST00000521738

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	5	159,274,388 - 159,275,333 (+)	Ensembl

RefSeq Acc Id:

NM_145049 ⟹ NP_659486

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	5	159,263,290 - 159,286,036 (+)	NCBI
GRCh37	5	158,690,089 - 158,713,048 (+)	RGD
Build 36	5	158,622,876 - 158,645,617 (+)	NCBI Archive
Celera	5	154,720,940 - 154,743,899 (+)	RGD
HuRef	5	153,784,215 - 153,807,159 (+)	ENTREZGENE
CHM1_1	5	158,122,533 - 158,145,488 (+)	NCBI
T2T-CHM13v2.0	5	159,791,779 - 159,814,534 (+)	NCBI

Sequence:

show sequence

ACTTCCGGTCGCTTTCGGTCTCTCAGCGGCCGGTTTCTGCGTCCGCTGCCGCAGGTTCCACCGC
GCTCCAGGTATTTTTTTTTCTGAAGGAAAGCTGCTTCCTCATATGTTTCAAGAATGGCTCTCCC
TATCATTGTAAAATGGGGTGGACAGGAGTATTCAGTGACCACACTTTCAGAAGATGATACTGTG
CTCGATCTCAAACAGTTTCTCAAGACCCTTACAGGAGTTCTTCCAGAACGCCAAAAGTTACTTG
GACTCAAAGTTAAAGGCAAACCTGCAGAAAATGATGTTAAGCTTGGAGCTCTCAAACTGAAACC
AAATACTAAAATCATGATGATGGGAACTCGTGAGGAGAGCTTGGAAGATGTCTTAGGTCCACCC
CCTGACAATGATGATGTTGTTAATGACTTTGATATTGAAGATGAAGTAGTTGAAGTAGAAAATA
GGGAAGAAAACCTACTGAAAATTTCTCGCAGAGTGAAAGAGTACAAAGTGGAAATTTTGAATCC
TCCCAGGGAAGGGAAAAAGCTTTTGGTGCTAGATGTTGATTATACATTATTTGACCACAGGTCT
TGTGCAGAGACTGGGGTAGAATTAATGCGGCCATATCTTCATGAATTTCTAACATCTGCCTATG
AAGATTATGACATTGTTATTTGGTCTGCAACAAATATGAAGTGGATTGAAGCTAAAATGAAAGA
GCTGGGAGTGAGCACAAATGCAAATTATAAGATTACTTTCATGTTGGATAGTGCTGCTATGATA
ACAGTACATACTCCAAGGAGAGGATTAATAGACGTAAAGCCTCTTGGTGTTATATGGGGAAAGT
TTTCGGAGTTTTACAGCAAGAAAAACACCATTATGTTTGATGACATAGGGAGAAATTTTCTAAT
GAACCCACAGAATGGACTAAAGATAAGGCCTTTTATGAAAGCGCACCTAAATCGTGATAAAGAC
AAAGAACTTTTAAAATTAACTCAGTACCTCAAGGAGATAGCAAAATTAGATGACTTTTTGGATC
TAAATCACAAATATTGGGAAAGATATCTCTCAAAGAAGCAAGGACAGTAGTTACAAGTTATACT
GGCAGTTATTGAAGATACTTAAGATCCAAGAACTTCTTGCTTTTATGCTAGAAATCATTATGAT
AGTGCTGGACACTGAAGCAAATACCATACTGCTTATACTTGGTCTTCCAGTTTTTTGTAAATTT
AATTTTATATTTTTTGAAGATGATAGCAATATGCTAAAAAATGCTTGTCCCCTATATGAATATT
CTGTTACGCTTGAAAAATATTTTCTCCAGCGTTGGTTACTGACCACCCCACCCTCCCACCACAC
ACACACACACACACACACACACACACACACACACACACACACAAAGTGGAGAAAAATGTATACT
CAACAATGTCATTTTGTGACTTTGGAAACAAGTTATGTTTTGTGTTTTTGTCTCATTGTGTTAT
TGTCTGACTAAATCTAAAACCAAACCCATGTTGAAACTAGTACTTTTCCCTTTAAAAACAAACC
AAAAAAAAAAACAAAAAAAAACTTTTTAATTAAAGAACCTAGTTTGCTATGCTTAAAATTACCA
AGAATTTTTTATTTCTTTGTCATAGACACAATTTCTCTTCTGTATGCCACTAGTTACATTTCTA
AATTCTGAGCGGTCTCAGTTAGGCCTGTATGTGTGTACATGTCCAAGTAAAGCTGGAAAATGTC
AGTCTTGACACAGCTGTGTCTTAGTATGAGAAACAGAAGACTGAAGAATAAAAACTAAGGAACA
AGAATGAGTCTCTTTTTGGTGGCTAAGTAGAATCTTCCTAAAACCATTGTCATAAAAGCAGTTA
AAGGCAATAAATTTTTAAAAGGGACATATCACTGATTCATTCCTAAAAAGCATGAACAAAAAGT
TTTTGTTCTGTTCCAGCTATATCTTGTCTAAGTGCTAACACTGTTTCAGTGAAAATATCTAGCC
ATAAGATTAAAAAAATATATTATTTGCAATGCTTAAGCCTGCAGATACGTAATGTGACCACTGT
TTTGTGTTGACAATATTGCTTTATACAGTTCTTGTATTTGAAAGGAATTGATCCTTTTAAAGAA
ACATGGTGTATATTGTTCTTACAGGACTAATTTCAGTGGTGTAAATAATAAATATCTTTTCTTA
AAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_659486	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAS68538	(Get FASTA)	NCBI Sequence Viewer
	BAB71628	(Get FASTA)	NCBI Sequence Viewer
	EAW61577	(Get FASTA)	NCBI Sequence Viewer
	EAW61578	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000296786
	ENSP00000296786.6
GenBank Protein	Q8WVY7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_659486 ⟸ NM_145049

- UniProtKB:

D3DQJ7 (UniProtKB/Swiss-Prot), Q96DK5 (UniProtKB/Swiss-Prot), Q8WVY7 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGAL
KLKPNTKIMMMGTREESLEDVLGPPPDNDDVVNDFDIEDEVVEVENREENLLKISRRVKEYKVE
ILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEA
KMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGR
NFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAKLDDFLDLNHKYWERYLSKKQGQ

hide sequence

RefSeq Acc Id:

ENSP00000296786 ⟸ ENST00000296786

Protein Domains

FCP1 homology Ubiquitin-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8WVY7-F1-model_v2	AlphaFold	Q8WVY7	1-318	view protein structure

Promoters

RGD ID:

6803629

Promoter ID:

HG_KWN:51667

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, CD4+TCell_2Hour, HeLa_S3, Jurkat, K562, Lymphoblastoid, NB4

Transcripts:

NM_145049

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	5	158,622,486 - 158,622,986 (+)	MPROMDB

RGD ID:

6871432

Promoter ID:

EPDNEW_H8881

Type:

initiation region

Name:

UBLCP1_1

Description:

ubiquitin like domain containing CTD phosphatase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H8880

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	5	159,263,290 - 159,263,350	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:28110	AgrOrtholog
COSMIC	UBLCP1	COSMIC
Ensembl Genes	ENSG00000164332	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000296786	ENTREZGENE
	ENST00000296786.8	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.1000	UniProtKB/Swiss-Prot
GTEx	ENSG00000164332	GTEx
HGNC ID	HGNC:28110	ENTREZGENE
Human Proteome Map	UBLCP1	Human Proteome Map
InterPro	FCP1_dom	UniProtKB/Swiss-Prot
	HAD-like_sf	UniProtKB/Swiss-Prot
	HAD-SF_hydro_IIID	UniProtKB/Swiss-Prot
	HAD_sf	UniProtKB/Swiss-Prot
	Ubiquitin-like_domsf	UniProtKB/Swiss-Prot
	Ubiquitin_dom	UniProtKB/Swiss-Prot
KEGG Report	hsa:134510	UniProtKB/Swiss-Prot
NCBI Gene	134510	ENTREZGENE
OMIM	609867	OMIM
PANTHER	UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1	UniProtKB/Swiss-Prot
	UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1	UniProtKB/Swiss-Prot
Pfam	NIF	UniProtKB/Swiss-Prot
	ubiquitin	UniProtKB/Swiss-Prot
PharmGKB	PA142670646	PharmGKB
PROSITE	FCP1	UniProtKB/Swiss-Prot
	UBIQUITIN_2	UniProtKB/Swiss-Prot
SMART	CPDc	UniProtKB/Swiss-Prot
	UBQ	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF54236	UniProtKB/Swiss-Prot
	SSF56784	UniProtKB/Swiss-Prot
UniProt	D3DQJ7	ENTREZGENE
	Q8WVY7	ENTREZGENE
	Q96DK5	ENTREZGENE
	UBCP1_HUMAN	UniProtKB/Swiss-Prot
UniProt Secondary	D3DQJ7	UniProtKB/Swiss-Prot
	Q96DK5	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-08	UBLCP1	ubiquitin like domain containing CTD phosphatase 1		ubiquitin-like domain containing CTD phosphatase 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD