Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of PDIA4 mRNA | CTD | PMID:28189721 and PMID:28960355 | 1,2-dimethylhydrazine | multiple interactions | ISO | Pdia4 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PDIA4 mRNA] | CTD | PMID:22206623 | 1,2-dimethylhydrazine | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of PDIA4 mRNA | CTD | PMID:22206623 | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | PDIA4 (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to PDIA4 protein | CTD | PMID:32991956 | 17alpha-ethynylestradiol | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of PDIA4 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | affects expression | ISO | Pdia4 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of PDIA4 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | ISO | Pdia4 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PDIA4 mRNA | CTD | PMID:17942748 | 17beta-estradiol | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Estradiol results in increased expression of PDIA4 mRNA | CTD | PMID:19484750 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of PDIA4 protein | CTD | PMID:32145629 | 17beta-estradiol | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of PDIA4 mRNA | CTD | PMID:30165855 | 17beta-hydroxy-5alpha-androstan-3-one | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Dihydrotestosterone results in decreased expression of PDIA4 mRNA | CTD | PMID:17023530 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of PDIA4 mRNA | CTD | PMID:29581250 | 1H-pyrazole | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | pyrazole results in increased expression of PDIA4 mRNA | CTD | PMID:17945193 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Pdia4 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PDIA4 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PDIA4 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PDIA4 mRNA | CTD | PMID:26290441 and PMID:33956508 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PDIA4 mRNA and Tetrachlorodibenzodioxin results in decreased expression of PDIA4 protein | CTD | PMID:16548065 and PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PDIA4 mRNA | CTD | PMID:17942748 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:18550172 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of PDIA4 mRNA | CTD | PMID:21346803 | 2-amino-2-deoxy-D-glucopyranose | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Glucosamine results in decreased expression of PDIA4 mRNA | CTD | PMID:17178593 | 2-hydroxypropanoic acid | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PDIA4 mRNA | CTD | PMID:30851411 | 2-palmitoylglycerol | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of PDIA4 mRNA | CTD | PMID:37199045 | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin analog results in decreased expression of PDIA4 protein and alpha-Chlorohydrin results in decreased expression of PDIA4 protein | CTD | PMID:26597043 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PDIA4 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of PDIA4 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of PDIA4 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of PDIA4 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of PDIA4 mRNA | CTD | PMID:36041667 | 4,4'-sulfonyldiphenol | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of PDIA4 protein | CTD | PMID:34186270 | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of PDIA4 mRNA | CTD | PMID:21346803 | 4-tert-Octylphenol | increases expression | EXP | | 6480464 | 4-tert-octylphenol results in increased expression of PDIA4 mRNA | CTD | PMID:17011747 | 5-fluorouracil | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Fluorouracil results in decreased expression of PDIA4 mRNA | CTD | PMID:16709241 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of PDIA4 mRNA | CTD | PMID:31881176 | aflatoxin B1 | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of PDIA4 mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of PDIA4 mRNA | CTD | PMID:33354967 | aflatoxin B1 | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of PDIA4 mRNA | CTD | PMID:27153756 | aldehydo-D-glucosamine | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Glucosamine results in decreased expression of PDIA4 mRNA | CTD | PMID:17178593 | aldehydo-D-glucose | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Glucose results in decreased expression of PDIA4 mRNA | CTD | PMID:17178593 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PDIA4 mRNA | CTD | PMID:16483693 | antimony(0) | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Antimony results in decreased expression of PDIA4 mRNA | CTD | PMID:17547211 | aristolochic acid A | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of PDIA4 mRNA | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of PDIA4 mRNA | CTD | PMID:23650126 | arsenite(3-) | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to PDIA4 protein] | CTD | PMID:32406909 | avobenzone | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | avobenzone results in increased expression of PDIA4 mRNA | CTD | PMID:31016361 | beauvericin | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | beauvericin results in decreased expression of PDIA4 mRNA | CTD | PMID:29203277 | benzo[a]pyrene | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PDIA4 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of PDIA4 protein | CTD | PMID:33278487 | beta-D-glucosamine | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Glucosamine results in decreased expression of PDIA4 mRNA | CTD | PMID:17178593 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PDIA4 mRNA and bisphenol A results in increased expression of PDIA4 protein | CTD | PMID:25181051 and PMID:32145629 | bisphenol A | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PDIA4 mRNA | CTD | PMID:37611474 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of PDIA4 mRNA | CTD | PMID:36041667 | bisphenol A | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PDIA4 protein | CTD | PMID:34186270 | bisphenol A | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | bisphenol A results in increased expression of PDIA4 protein | CTD | PMID:28279065 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PDIA4 mRNA | CTD | PMID:30816183 | Bisphenol B | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of PDIA4 protein | CTD | PMID:34186270 | bisphenol F | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PDIA4 mRNA | CTD | PMID:28628672 | bisphenol F | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of PDIA4 protein | CTD | PMID:34186270 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of PDIA4 mRNA | CTD | PMID:36041667 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of PDIA4 mRNA | CTD | PMID:21297351 | cadmium dichloride | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of PDIA4 mRNA | CTD | PMID:30796460 | caffeine | increases phosphorylation | ISO | PDIA4 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of PDIA4 protein | CTD | PMID:35688186 | carbon nanotube | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | carboplatin | decreases expression | EXP | | 6480464 | Carboplatin results in decreased expression of PDIA4 mRNA | CTD | PMID:18172885 | cefaloridine | increases expression | EXP | | 6480464 | Cephaloridine results in increased expression of PDIA4 mRNA | CTD | PMID:18172885 | ceruletide | increases expression | EXP | | 6480464 | Ceruletide results in increased expression of PDIA4 protein | CTD | PMID:18024178 | CGP 52608 | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PDIA4 gene] | CTD | PMID:28238834 | chromium atom | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Chromium results in decreased expression of PDIA4 mRNA | CTD | PMID:17547211 | cisplatin | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of PDIA4 mRNA | CTD | PMID:11099651 and PMID:27594783 | cisplatin | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of PDIA4 mRNA | CTD | PMID:27392435 | clobetasol | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Clobetasol results in increased expression of PDIA4 mRNA | CTD | PMID:27462272 | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of PDIA4 mRNA | CTD | PMID:15033592 | clotrimazole | increases expression | EXP | | 6480464 | Clotrimazole results in increased expression of PDIA4 mRNA | CTD | PMID:30047161 | clozapine | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Clozapine] results in decreased expression of PDIA4 protein | CTD | PMID:34122009 | cobalt dichloride | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of PDIA4 mRNA | CTD | PMID:19320972 | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of PDIA4 mRNA | CTD | PMID:20187946 | copper atom | multiple interactions | ISO | Pdia4 (Mus musculus) | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of PDIA4 mRNA | CTD | PMID:15467011 | copper(0) | multiple interactions | ISO | Pdia4 (Mus musculus) | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of PDIA4 mRNA | CTD | PMID:15467011 | copper(II) sulfate | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of PDIA4 mRNA | CTD | PMID:19549813 | coumarin | increases expression | EXP | | 6480464 | coumarin results in increased expression of PDIA4 mRNA | CTD | PMID:18480146 | CU-O LINKAGE | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | cupric oxide results in decreased expression of PDIA4 protein | CTD | PMID:25470785 | Cuprizon | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Clozapine] results in decreased expression of PDIA4 protein | CTD | PMID:34122009 | cyclophosphamide | increases expression | EXP | | 6480464 | Cyclophosphamide results in increased expression of PDIA4 mRNA | CTD | PMID:11599041 | cyclosporin A | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of PDIA4 mRNA and Cyclosporine results in increased expression of PDIA4 protein | CTD | PMID:23308384 and PMID:25047351 | cyclosporin A | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PDIA4 mRNA | CTD | PMID:20106945 more ... | D-glucose | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Glucose results in decreased expression of PDIA4 mRNA | CTD | PMID:17178593 | dexamethasone | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PDIA4 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of PDIA4 mRNA | CTD | PMID:28628672 | diamminedichloroplatinum | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | transplatin results in decreased expression of PDIA4 mRNA | CTD | PMID:11099651 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in decreased expression of PDIA4 mRNA | CTD | PMID:18636392 | dichlorine | increases expression | EXP | | 6480464 | Chlorine results in increased expression of PDIA4 mRNA | CTD | PMID:18636392 | dichloroacetic acid | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Dichloroacetic Acid results in decreased expression of PDIA4 mRNA | CTD | PMID:28962523 | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of PDIA4 mRNA | CTD | PMID:17011747 | diethylstilbestrol | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Diethylstilbestrol results in increased expression of PDIA4 mRNA | CTD | PMID:36621641 | dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Antimony Potassium Tartrate results in decreased expression of PDIA4 mRNA | CTD | PMID:17547211 | doxorubicin | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PDIA4 mRNA | CTD | PMID:29803840 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of PDIA4 mRNA | CTD | PMID:29391264 | ethanol | affects expression | ISO | Pdia4 (Mus musculus) | 6480464 | Ethanol affects the expression of PDIA4 mRNA | CTD | PMID:30319688 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of PDIA4 mRNA | CTD | PMID:24793618 | folic acid | multiple interactions | ISO | Pdia4 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PDIA4 mRNA] | CTD | PMID:22206623 | folic acid | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PDIA4 mRNA | CTD | PMID:25629700 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PDIA4 mRNA | CTD | PMID:18172885 and PMID:33387578 | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of PDIA4 mRNA | CTD | PMID:24136188 | glucose | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Glucose results in decreased expression of PDIA4 mRNA | CTD | PMID:17178593 | indometacin | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PDIA4 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of PDIA4 mRNA | CTD | PMID:28628672 | isobutanol | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of PDIA4 mRNA | CTD | PMID:29432896 | isoprenaline | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of PDIA4 mRNA | CTD | PMID:21335049 and PMID:21823215 | ivermectin | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PDIA4 protein | CTD | PMID:32959892 | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of PDIA4 mRNA | CTD | PMID:20080153 | lipopolysaccharide | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of PDIA4 mRNA | CTD | PMID:35877022 | lovastatin | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Lovastatin results in decreased expression of PDIA4 mRNA | CTD | PMID:20493250 | mercury atom | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Mercury results in decreased expression of PDIA4 mRNA | CTD | PMID:17547211 | mercury(0) | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Mercury results in decreased expression of PDIA4 mRNA | CTD | PMID:17547211 | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of PDIA4 mRNA | CTD | PMID:19564919 | methamphetamine | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Methamphetamine results in increased expression of PDIA4 mRNA | CTD | PMID:36914120 | methamphetamine | multiple interactions | EXP | | 6480464 | SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PDIA4 mRNA] | CTD | PMID:19564919 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of PDIA4 mRNA | CTD | PMID:30467583 | methylparaben | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | methylparaben results in increased expression of PDIA4 mRNA | CTD | PMID:31745603 | microcystin-LR | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | cyanoginosin LR results in decreased expression of PDIA4 mRNA | CTD | PMID:17383702 | monosodium L-glutamate | multiple interactions | ISO | Pdia4 (Mus musculus) | 6480464 | [Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of PDIA4 mRNA and [Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of PDIA4 mRNA | CTD | PMID:20111022 and PMID:22078008 | monosodium L-glutamate | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Sodium Glutamate results in decreased expression of PDIA4 mRNA | CTD | PMID:22078008 | N-nitrosodimethylamine | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Dimethylnitrosamine results in decreased expression of PDIA4 mRNA | CTD | PMID:17547211 | N-nitrosomorpholine | decreases expression | EXP | | 6480464 | N-nitrosomorpholine results in decreased expression of PDIA4 protein | CTD | PMID:19716841 | nickel atom | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Nickel results in increased expression of PDIA4 mRNA | CTD | PMID:25583101 | nickel dichloride | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | nickel chloride results in decreased expression of PDIA4 mRNA | CTD | PMID:17547211 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of PDIA4 mRNA | CTD | PMID:24136188 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in decreased expression of PDIA4 mRNA | CTD | PMID:18636392 | p-tert-Amylphenol | increases expression | EXP | | 6480464 | 4-tert-octylphenol results in increased expression of PDIA4 mRNA | CTD | PMID:17011747 | paracetamol | affects expression | ISO | Pdia4 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PDIA4 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PDIA4 mRNA | CTD | PMID:33387578 | paracetamol | increases oxidation | ISO | Pdia4 (Mus musculus) | 6480464 | Acetaminophen results in increased oxidation of PDIA4 protein | CTD | PMID:19931551 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of PDIA4 mRNA | CTD | PMID:17935786 | perfluorononanoic acid | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of PDIA4 mRNA | CTD | PMID:32588087 | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of PDIA4 mRNA | CTD | PMID:19162173 | perfluorooctanoic acid | affects expression | ISO | Pdia4 (Mus musculus) | 6480464 | perfluorooctanoic acid affects the expression of PDIA4 mRNA | CTD | PMID:32578922 | phenobarbital | affects expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of PDIA4 mRNA | CTD | PMID:19159669 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of PDIA4 mRNA | CTD | PMID:30047161 | PhIP | increases expression | EXP | | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of PDIA4 mRNA | CTD | PMID:15215175 | potassium dichromate | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Potassium Dichromate results in decreased expression of PDIA4 mRNA | CTD | PMID:17547211 | procymidone | decreases expression | EXP | | 6480464 | procymidone results in decreased expression of PDIA4 mRNA | CTD | PMID:15686871 | progesterone | affects expression | ISO | Pdia4 (Mus musculus) | 6480464 | Progesterone affects the expression of PDIA4 mRNA | CTD | PMID:17251523 | propiconazole | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | propiconazole results in increased expression of PDIA4 mRNA | CTD | PMID:21278054 | prostaglandin F2alpha | decreases expression | EXP | | 6480464 | Dinoprost results in decreased expression of PDIA4 mRNA | CTD | PMID:11517196 | rac-lactic acid | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PDIA4 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | Pdia4 (Mus musculus) | 6480464 | Resveratrol inhibits the reaction [titanium dioxide results in increased expression of PDIA4 mRNA] | CTD | PMID:31298478 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of PDIA4 mRNA | CTD | PMID:28374803 | SB 431542 | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of PDIA4 protein | CTD | PMID:37664457 | SCH 23390 | multiple interactions | EXP | | 6480464 | SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PDIA4 mRNA] | CTD | PMID:19564919 | sodium arsenate | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of PDIA4 mRNA | CTD | PMID:21795629 | sodium arsenite | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PDIA4 mRNA | CTD | PMID:20371982 more ... | sodium arsenite | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of PDIA4 mRNA | CTD | PMID:37682722 | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of PDIA4 mRNA | CTD | PMID:12325037 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of PDIA4 mRNA | CTD | PMID:30047161 | T-2 toxin | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | T-2 Toxin results in decreased expression of PDIA4 mRNA | CTD | PMID:31863870 | tacrolimus hydrate | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Tacrolimus results in increased expression of PDIA4 mRNA | CTD | PMID:25270620 | tamoxifen | affects expression | ISO | Pdia4 (Mus musculus) | 6480464 | Tamoxifen affects the expression of PDIA4 mRNA | CTD | PMID:17555576 | tanespimycin | multiple interactions | ISO | PDIA4 (Homo sapiens) | 6480464 | [tanespimycin co-treated with VER 155008] results in increased expression of PDIA4 protein | CTD | PMID:31370342 | tert-butyl hydroperoxide | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | tert-Butylhydroperoxide results in decreased expression of PDIA4 mRNA | CTD | PMID:15003993 | tetrachloromethane | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of PDIA4 mRNA | CTD | PMID:31919559 | thapsigargin | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of PDIA4 mRNA and Thapsigargin results in increased expression of PDIA4 protein | CTD | PMID:22378314 and PMID:29453283 | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of PDIA4 protein | CTD | PMID:35544339 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of PDIA4 mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of PDIA4 mRNA | CTD | PMID:23557971 and PMID:31298478 | titanium dioxide | multiple interactions | ISO | Pdia4 (Mus musculus) | 6480464 | Resveratrol inhibits the reaction [titanium dioxide results in increased expression of PDIA4 mRNA] | CTD | PMID:31298478 | transplatin | decreases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | transplatin results in decreased expression of PDIA4 mRNA | CTD | PMID:11099651 | triadimefon | increases expression | EXP | | 6480464 | triadimefon results in increased expression of PDIA4 mRNA | CTD | PMID:30047161 | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of PDIA4 protein | CTD | PMID:21315101 | tungsten | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Tungsten results in decreased expression of PDIA4 mRNA | CTD | PMID:30912803 | tunicamycin | increases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Tunicamycin results in increased expression of PDIA4 mRNA | CTD | PMID:17127020 | tunicamycin | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of PDIA4 mRNA and Tunicamycin results in increased expression of PDIA4 protein | CTD | PMID:22378314 and PMID:29453283 | valproic acid | affects expression | ISO | Pdia4 (Mus musculus) | 6480464 | Valproic Acid affects the expression of PDIA4 mRNA | CTD | PMID:17292431 | valproic acid | affects expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PDIA4 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PDIA4 mRNA | CTD | PMID:23179753 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of PDIA4 mRNA | CTD | PMID:15686871 and PMID:23034163 | warfarin | decreases expression | ISO | Pdia4 (Mus musculus) | 6480464 | Warfarin results in decreased expression of PDIA4 mRNA | CTD | PMID:20493250 | zinc atom | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Zinc deficiency results in increased expression of PDIA4 mRNA | CTD | PMID:22171008 | zinc(0) | increases expression | ISO | PDIA4 (Homo sapiens) | 6480464 | Zinc deficiency results in increased expression of PDIA4 mRNA | CTD | PMID:22171008 | |