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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619835
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdia4
Name: protein disulfide isomerase family A, member 4
Acc ID: CHEBI:6809
Term: methamphetamine
Definition: A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
Chemical ID: MESH:D008694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdia4increases expressionEXP 6480464CTDMethamphetamine results in increased expression of PDIA4 mRNAPMID:19564919
Pdia4multiple interactionsEXP 6480464CTDSCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PDIA4 mRNA]PMID:19564919
Pdia4increases expressionISOPdia4 (Mus musculus)6480464CTDMethamphetamine results in increased expression of PDIA4 mRNAPMID:36914120
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