Pou3f2 (POU class 3 homeobox 2) - Rat Genome Database

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Pathways
Gene: Pou3f2 (POU class 3 homeobox 2) Rattus norvegicus
Analyze
Symbol: Pou3f2
Name: POU class 3 homeobox 2
RGD ID: 61946
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and sequence-specific DNA binding activity. Involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Orthologous to human POU3F2 (POU class 3 homeobox 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: brain-2; brain-specific homeobox/POU domain protein 2; Brn-2; nervous system-specific octamer-binding transcription factor N-Oct-3; oct-7; octamer-binding protein 7; octamer-binding transcription factor 7; OTF-7; POU domain, class 3, transcription factor 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8540,874,631 - 40,880,539 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl540,874,601 - 40,881,010 (-)EnsemblGRCr8
mRatBN7.2536,077,930 - 36,083,838 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl536,077,930 - 36,083,838 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx538,207,622 - 38,213,515 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0539,800,219 - 39,806,116 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0539,739,886 - 39,745,785 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0536,677,452 - 36,683,356 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl536,681,528 - 36,683,356 (-)Ensemblrn6Rnor6.0
Rnor_5.0541,323,568 - 41,325,396 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4537,281,880 - 37,283,708 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera535,088,092 - 35,093,981 (-)NCBICelera
RGSC_v3.1537,282,058 - 37,283,887 (-)NCBI
Cytogenetic Map5q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO)
transcription regulator complex  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Sp1- and octamer-consensus sequence binding proteins during lens fibre differentiation. Brunekreef GA, etal., Exp Eye Res. 1997 Mar;64(3):295-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Tst-1, a member of the POU domain gene family, binds the promoter of the gene encoding the cell surface adhesion molecule P0. He X, etal., Mol Cell Biol 1991 Mar;11(3):1739-44.
5. RHS2, a POU domain-containing gene, and its expression in developing and adult rat. Le Moine C and Young WS 3rd, Proc Natl Acad Sci U S A 1992 Apr 15;89(8):3285-9.
6. Spacing and orientation of bipartite DNA-binding motifs as potential functional determinants for POU domain factors. Li P, etal., Genes Dev 1993 Dec;7(12B):2483-96.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Expression and activity of the POU transcription factor SCIP. Monuki ES, etal., Science 1990 Sep 14;249(4974):1300-3.
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Redundancy of class III POU proteins in the oligodendrocyte lineage. Schreiber J, etal., J Biol Chem 1997 Dec 19;272(51):32286-93.
13. Identification of novel domains within Sox-2 and Sox-11 involved in autoinhibition of DNA binding and partnership specificity. Wiebe MS, etal., J Biol Chem. 2003 May 16;278(20):17901-11. Epub 2003 Mar 10.
Additional References at PubMed
PMID:8543156   PMID:8593698   PMID:9105675   PMID:11029584   PMID:12130536   PMID:12782656   PMID:15024079   PMID:15465489   PMID:17141158   PMID:18403418   PMID:18505825   PMID:18794345  
PMID:23069940   PMID:24243019  


Genomics

Comparative Map Data
Pou3f2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8540,874,631 - 40,880,539 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl540,874,601 - 40,881,010 (-)EnsemblGRCr8
mRatBN7.2536,077,930 - 36,083,838 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl536,077,930 - 36,083,838 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx538,207,622 - 38,213,515 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0539,800,219 - 39,806,116 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0539,739,886 - 39,745,785 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0536,677,452 - 36,683,356 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl536,681,528 - 36,683,356 (-)Ensemblrn6Rnor6.0
Rnor_5.0541,323,568 - 41,325,396 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4537,281,880 - 37,283,708 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera535,088,092 - 35,093,981 (-)NCBICelera
RGSC_v3.1537,282,058 - 37,283,887 (-)NCBI
Cytogenetic Map5q21NCBI
POU3F2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38698,834,574 - 98,839,458 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl698,834,574 - 98,839,458 (+)Ensemblhg38GRCh38
GRCh37699,282,450 - 99,287,334 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36699,389,301 - 99,393,387 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34699,389,300 - 99,393,386NCBI
Celera699,926,767 - 99,930,852 (+)NCBICelera
Cytogenetic Map6q16.1NCBI
HuRef696,721,681 - 96,725,451 (+)NCBIHuRef
CHM1_1699,545,501 - 99,549,586 (+)NCBICHM1_1
T2T-CHM13v2.06100,008,944 - 100,013,827 (+)NCBIT2T-CHM13v2.0
Pou3f2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39422,482,095 - 22,488,366 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl422,482,780 - 22,488,366 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38422,482,095 - 22,488,366 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl422,482,780 - 22,488,366 (-)Ensemblmm10GRCm38
MGSCv37422,413,941 - 22,415,278 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36422,577,629 - 22,578,966 (-)NCBIMGSCv36mm8
Celera422,241,121 - 22,242,061 (-)NCBICelera
Cytogenetic Map4A3NCBI
cM Map49.73NCBI
Pou3f2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541124,715,088 - 24,716,695 (+)Ensembl
ChiLan1.0NW_00495541124,714,899 - 24,722,048 (+)NCBIChiLan1.0ChiLan1.0
POU3F2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25118,883,277 - 118,887,764 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16116,764,439 - 116,768,944 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0696,677,651 - 96,682,145 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16100,558,883 - 100,564,670 (+)NCBIPanPan1.1PanPan1.1panPan2
POU3F2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11257,103,712 - 57,108,522 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1256,862,028 - 56,869,251 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01257,925,134 - 57,932,364 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1257,925,422 - 57,926,753 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11257,285,124 - 57,292,343 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01257,128,337 - 57,135,538 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01257,373,160 - 57,380,387 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pou3f2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494692,038,759 - 92,044,841 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936651493,467 - 494,832 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936651494,182 - 497,109 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POU3F2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl165,835,995 - 65,837,323 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1165,835,375 - 65,842,872 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2174,386,105 - 74,390,348 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POU3F2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11375,027,360 - 75,032,222 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1375,030,677 - 75,032,008 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604047,357,232 - 47,362,553 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pou3f2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248106,286,066 - 6,287,397 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248106,283,443 - 6,287,594 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Pou3f2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11120,849,091 - 120,850,789 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pou3f2
35 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:59
Interacting mature miRNAs:66
Transcripts:ENSRNOT00000009043
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)51373115343590997Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5862723052665523Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1578774Tcas8Tongue tumor susceptibility QTL 83.47tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)51570745160707451Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1549901Neudeg2Neurodegradation QTL 240nervous system integrity trait (VT:0010566)mononuclear cell count (CMO:0002119)53113042148841739Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5862723053627230Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51460607859606078Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat

Markers in Region
PMC196070P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2536,083,588 - 36,083,812 (+)MAPPERmRatBN7.2
Rnor_6.0536,683,107 - 36,683,330NCBIRnor6.0
Rnor_5.0541,325,147 - 41,325,370UniSTSRnor5.0
RGSC_v3.4537,283,459 - 37,283,682UniSTSRGSC3.4
Celera535,093,732 - 35,093,955UniSTS
Cytogenetic Map5q21UniSTS
PMC317216P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2536,082,170 - 36,082,940 (+)MAPPERmRatBN7.2
Rnor_6.0536,681,689 - 36,682,458NCBIRnor6.0
Rnor_5.0541,323,729 - 41,324,498UniSTSRnor5.0
RGSC_v3.4537,282,041 - 37,282,810UniSTSRGSC3.4
Celera535,092,315 - 35,093,083UniSTS
Cytogenetic Map5q21UniSTS
Pou3f2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2536,083,276 - 36,083,464 (+)MAPPERmRatBN7.2
Rnor_6.0536,682,795 - 36,682,982NCBIRnor6.0
Rnor_5.0541,324,835 - 41,325,022UniSTSRnor5.0
RGSC_v3.4537,283,147 - 37,283,334UniSTSRGSC3.4
Celera535,093,420 - 35,093,607UniSTS
Cytogenetic Map5q21UniSTS
UniSTS:492577  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2536,082,376 - 36,083,824 (+)MAPPERmRatBN7.2
Rnor_6.0536,681,895 - 36,683,342NCBIRnor6.0
Rnor_5.0541,323,935 - 41,325,382UniSTSRnor5.0
RGSC_v3.4537,282,247 - 37,283,694UniSTSRGSC3.4
Celera535,092,520 - 35,093,967UniSTS
Cytogenetic Map5q21UniSTS
Pou3f2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2536,082,723 - 36,083,453 (+)MAPPERmRatBN7.2
Rnor_6.0536,682,242 - 36,682,971NCBIRnor6.0
Rnor_5.0541,324,282 - 41,325,011UniSTSRnor5.0
Celera535,092,867 - 35,093,596UniSTS
Cytogenetic Map5q21UniSTS
Pou3f2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2536,083,198 - 36,083,729 (+)MAPPERmRatBN7.2
Rnor_6.0536,682,717 - 36,683,247NCBIRnor6.0
Rnor_5.0541,324,757 - 41,325,287UniSTSRnor5.0
Celera535,093,342 - 35,093,872UniSTS
Cytogenetic Map5q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 10 22 143 63 62 31 30 31 6 152 76 2 129 27 66 31 13 13

Sequence


Ensembl Acc Id: ENSRNOT00000009043   ⟹   ENSRNOP00000009043
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl536,681,528 - 36,683,356 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120257   ⟹   ENSRNOP00000078344
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl540,874,601 - 40,881,010 (-)Ensembl
mRatBN7.2 Ensembl536,077,930 - 36,083,838 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000129093   ⟹   ENSRNOP00000111314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl540,878,131 - 40,880,668 (-)Ensembl
RefSeq Acc Id: NM_172085   ⟹   NP_742082
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,874,631 - 40,880,539 (-)NCBI
mRatBN7.2536,077,930 - 36,083,838 (-)NCBI
Rnor_6.0536,677,452 - 36,683,356 (-)NCBI
Rnor_5.0541,323,568 - 41,325,396 (-)NCBI
RGSC_v3.4537,281,880 - 37,283,708 (-)RGD
Celera535,088,092 - 35,093,981 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_742082 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL98532 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000078344
GenBank Protein P56222 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_742082   ⟸   NM_172085
- UniProtKB: P56222 (UniProtKB/Swiss-Prot),   G3V6U5 (UniProtKB/TrEMBL),   A6IIG2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009043   ⟸   ENSRNOT00000009043
Ensembl Acc Id: ENSRNOP00000078344   ⟸   ENSRNOT00000120257
Ensembl Acc Id: ENSRNOP00000111314   ⟸   ENSRNOT00000129093
Protein Domains
Homeobox   POU-specific

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P56222-F1-model_v2 AlphaFold P56222 1-445 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61946 AgrOrtholog
BioCyc Gene G2FUF-41801 BioCyc
Ensembl Genes ENSRNOG00000006908 Ensembl
  ENSRNOG00000063836 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000120257 ENTREZGENE
Gene3D-CATH 1.10.260.40 UniProtKB/Swiss-Prot
  Homeodomain-like UniProtKB/Swiss-Prot
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot
  Homeobox_CS UniProtKB/Swiss-Prot
  Homeobox_dom UniProtKB/Swiss-Prot
  Lambda_DNA-bd_dom_sf UniProtKB/Swiss-Prot
  POU UniProtKB/Swiss-Prot
  POU_dom UniProtKB/Swiss-Prot
  POU_domain_TF UniProtKB/Swiss-Prot
  TF_POU_3 UniProtKB/Swiss-Prot
NCBI Gene 29588 ENTREZGENE
PANTHER POU DOMAIN UniProtKB/Swiss-Prot
  POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 2 UniProtKB/Swiss-Prot
Pfam Homeodomain UniProtKB/Swiss-Prot
  Pou UniProtKB/Swiss-Prot
PhenoGen Pou3f2 PhenoGen
PIRSF Transcription_factor_POU UniProtKB/Swiss-Prot
PRINTS POUDOMAIN UniProtKB/Swiss-Prot
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot
  HOMEOBOX_2 UniProtKB/Swiss-Prot
  POU_1 UniProtKB/Swiss-Prot
  POU_2 UniProtKB/Swiss-Prot
  POU_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000006908 RatGTEx
  ENSRNOG00000063836 RatGTEx
SMART HOX UniProtKB/Swiss-Prot
  POU UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot
  SSF47413 UniProtKB/Swiss-Prot
UniProt A0ABK0LY29_RAT UniProtKB/TrEMBL
  A6IIG2 ENTREZGENE, UniProtKB/TrEMBL
  G3V6U5 ENTREZGENE, UniProtKB/TrEMBL
  P56222 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-24 Pou3f2  POU class 3 homeobox 2  Pou3f2  POU domain, class 3, transcription factor 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Pou3f2  POU domain, class 3, transcription factor 2      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference