Tgm1 (transglutaminase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Tgm1 (transglutaminase 1) Rattus norvegicus
Analyze
Symbol: Tgm1
Name: transglutaminase 1
RGD ID: 61838
Description: Predicted to enable identical protein binding activity and protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in keratinocyte differentiation; positive regulation of cell cycle; and positive regulation of keratinocyte proliferation. Predicted to act upstream of or within animal organ morphogenesis. Predicted to be located in adherens junction and membrane. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1. Orthologous to human TGM1 (transglutaminase 1); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: epidermal TGase; glutamine gamma-glutamyltransferase K; protein-glutamine gamma-glutamyltransferase K; TG(K); TGase K; TGase-1; TGK; transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase); transglutaminase 1 K polypeptide; transglutaminase 1, K polypeptide; transglutaminase K; transglutaminase-1
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81533,160,985 - 33,175,632 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1533,160,987 - 33,174,463 (-)EnsemblGRCr8
mRatBN7.21529,191,039 - 29,206,000 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,191,041 - 29,204,523 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1531,036,752 - 31,049,999 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01532,183,977 - 32,197,224 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,426,310 - 30,439,558 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,378,136 - 34,393,150 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,378,148 - 34,392,066 (-)Ensemblrn6Rnor6.0
Rnor_5.01538,268,112 - 38,282,132 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41533,846,367 - 33,859,615 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1528,767,463 - 28,780,710 (-)NCBICelera
RGSC_v3.11533,862,066 - 33,875,315 (-)NCBI
Cytogenetic Map15p13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,8-cineole  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-Hydroxybenzophenone  (ISO)
9-cis-retinoic acid  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (EXP)
alpha-Zearalanol  (EXP)
amitriptyline  (EXP)
ammonium chloride  (EXP)
antimonite  (ISO)
aristolochic acid A  (ISO)
arotinoid acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (ISO)
cortisol  (ISO)
cyclosporin A  (EXP,ISO)
cyhalothrin  (EXP)
cypermethrin  (EXP)
dibenz[a,h]anthracene  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
endosulfan  (EXP)
fenvalerate  (EXP)
flavonoids  (EXP)
furan  (ISO)
furfural  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glycidol  (EXP)
indole-3-methanol  (EXP)
isotretinoin  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (EXP)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP)
naphthalene  (ISO)
nickel atom  (ISO)
nitrobenzenes  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
parathion-methyl  (EXP)
pentane-2,3-dione  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
pyrethrins  (EXP)
rac-lactic acid  (ISO)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (EXP)
sulforaphane  (ISO)
tacrolimus hydrate  (EXP)
tamoxifen  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
undecane  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
adherens junction  (ISO)
cytosol  (IEA,ISO,ISS)
membrane  (IEA,ISO)
plasma membrane  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Mutations of keratinocyte transglutaminase in lamellar ichthyosis. Huber M, etal., Science. 1995 Jan 27;267(5197):525-8.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Primary structure of keratinocyte transglutaminase. Phillips MA, etal., Proc Natl Acad Sci U S A 1990 Dec;87(23):9333-7.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:7961731   PMID:8824274   PMID:9722562   PMID:10567386   PMID:12477932   PMID:16604191   PMID:16997488   PMID:18003782   PMID:19182904   PMID:19199708   PMID:21282207   PMID:22573678  
PMID:25599570   PMID:25931508   PMID:26220141   PMID:29476059  


Genomics

Comparative Map Data
Tgm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81533,160,985 - 33,175,632 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1533,160,987 - 33,174,463 (-)EnsemblGRCr8
mRatBN7.21529,191,039 - 29,206,000 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,191,041 - 29,204,523 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1531,036,752 - 31,049,999 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01532,183,977 - 32,197,224 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,426,310 - 30,439,558 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,378,136 - 34,393,150 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,378,148 - 34,392,066 (-)Ensemblrn6Rnor6.0
Rnor_5.01538,268,112 - 38,282,132 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41533,846,367 - 33,859,615 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1528,767,463 - 28,780,710 (-)NCBICelera
RGSC_v3.11533,862,066 - 33,875,315 (-)NCBI
Cytogenetic Map15p13NCBI
TGM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,249,114 - 24,263,177 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,249,114 - 24,264,432 (-)Ensemblhg38GRCh38
GRCh371424,718,320 - 24,732,383 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,788,160 - 23,802,256 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341423,788,161 - 23,802,212NCBI
Celera144,582,959 - 4,597,032 (-)NCBICelera
Cytogenetic Map14q12NCBI
HuRef144,833,089 - 4,847,573 (-)NCBIHuRef
CHM1_11424,716,943 - 24,731,017 (-)NCBICHM1_1
T2T-CHM13v2.01418,447,487 - 18,461,522 (-)NCBIT2T-CHM13v2.0
Tgm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,937,466 - 55,951,378 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,937,466 - 55,951,383 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381455,700,009 - 55,713,921 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,700,009 - 55,713,926 (-)Ensemblmm10GRCm38
MGSCv371456,318,846 - 56,332,329 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361454,654,090 - 54,667,159 (-)NCBIMGSCv36mm8
Celera1453,505,022 - 53,518,505 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
TGM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,604,115 - 25,618,834 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,820,632 - 24,836,103 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,025,345 - 5,041,557 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11423,148,905 - 23,163,249 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1423,148,905 - 23,162,477 (-)EnsemblpanPan2panpan1.1
TGM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,229,410 - 4,244,768 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,229,614 - 4,241,644 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha84,151,291 - 4,163,321 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.084,340,192 - 4,355,545 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,340,391 - 4,352,420 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.184,030,778 - 4,042,799 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.084,092,571 - 4,104,607 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,354,922 - 4,366,945 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tgm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864036,082,429 - 36,096,863 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722292,143 - 306,572 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936722292,999 - 306,540 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TGM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,029,923 - 75,047,300 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1775,030,123 - 75,045,157 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,298,974 - 80,316,080 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TGM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,231,827 - 1,248,018 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,232,004 - 1,245,462 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603612,916,544 - 12,930,178 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tgm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,239,904 - 8,252,541 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248208,239,087 - 8,252,716 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tgm1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11269,296,218 - 69,309,517 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tgm1
60 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:145
Count of miRNA genes:110
Interacting mature miRNAs:124
Transcripts:ENSRNOT00000027315
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 9 67 161 91 90 59 92 59 6 350 192 11 140 78 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001431338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006252014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC116083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC097305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM669278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M57263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000027315   ⟹   ENSRNOP00000027315
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1533,160,987 - 33,174,463 (-)Ensembl
mRatBN7.2 Ensembl1529,191,041 - 29,204,523 (-)Ensembl
Rnor_6.0 Ensembl1534,378,148 - 34,392,066 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119383   ⟹   ENSRNOP00000084357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1533,160,987 - 33,173,800 (-)Ensembl
mRatBN7.2 Ensembl1529,191,041 - 29,204,146 (-)Ensembl
RefSeq Acc Id: NM_031659   ⟹   NP_113847
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,161,019 - 33,174,267 (-)NCBI
mRatBN7.21529,191,073 - 29,204,327 (-)NCBI
Rnor_6.01534,378,170 - 34,391,418 (-)NCBI
Rnor_5.01538,268,112 - 38,282,132 (-)NCBI
RGSC_v3.41533,846,367 - 33,859,615 (-)RGD
Celera1528,767,463 - 28,780,710 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252014   ⟹   XP_006252076
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,160,985 - 33,175,632 (-)NCBI
mRatBN7.21529,191,039 - 29,206,000 (-)NCBI
Rnor_6.01534,378,136 - 34,393,150 (-)NCBI
Rnor_5.01538,268,112 - 38,282,132 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770691   ⟹   XP_008768913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,160,985 - 33,175,632 (-)NCBI
mRatBN7.21529,191,039 - 29,206,000 (-)NCBI
Rnor_6.01534,378,136 - 34,393,150 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093624   ⟹   XP_038949552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,160,985 - 33,175,632 (-)NCBI
mRatBN7.21529,191,039 - 29,206,000 (-)NCBI
RefSeq Acc Id: XM_063274599   ⟹   XP_063130669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81533,160,985 - 33,175,632 (-)NCBI
RefSeq Acc Id: NP_113847   ⟸   NM_031659
- UniProtKB: Q4QRA6 (UniProtKB/Swiss-Prot),   P23606 (UniProtKB/Swiss-Prot),   A6KH40 (UniProtKB/TrEMBL),   A0A8I5ZX14 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252076   ⟸   XM_006252014
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008768913   ⟸   XM_008770691
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000027315   ⟸   ENSRNOT00000027315
RefSeq Acc Id: XP_038949552   ⟸   XM_039093624
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000084357   ⟸   ENSRNOT00000119383
RefSeq Acc Id: XP_063130669   ⟸   XM_063274599
- Peptide Label: isoform X2
Protein Domains
Transglutaminase-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P23606-F1-model_v2 AlphaFold P23606 1-824 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699685
Promoter ID:EPDNEW_R10208
Type:single initiation site
Name:Tgm1_1
Description:transglutaminase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01534,391,616 - 34,391,676EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61838 AgrOrtholog
BioCyc Gene G2FUF-13696 BioCyc
Ensembl Genes ENSRNOG00000020136 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000027315 ENTREZGENE
  ENSRNOT00000027315.6 UniProtKB/Swiss-Prot
  ENSRNOT00000119383 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
  3.90.260.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7462186 IMAGE-MGC_LOAD
InterPro Ig-like_fold UniProtKB/Swiss-Prot
  Ig_E-set UniProtKB/Swiss-Prot
  Papain-like_cys_pep_sf UniProtKB/Swiss-Prot
  Transglutaminase UniProtKB/Swiss-Prot
  Transglutaminase-like UniProtKB/Swiss-Prot
  Transglutaminase-like_sf UniProtKB/Swiss-Prot
  Transglutaminase_animal UniProtKB/Swiss-Prot
  Transglutaminase_AS UniProtKB/Swiss-Prot
  Transglutaminase_C UniProtKB/Swiss-Prot
  Transglutaminase_C_sf UniProtKB/Swiss-Prot
  Transglutaminase_N UniProtKB/Swiss-Prot
KEGG Report rno:60335 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114300 IMAGE-MGC_LOAD
NCBI Gene 60335 ENTREZGENE
PANTHER PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE UniProtKB/Swiss-Prot
  PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE K UniProtKB/Swiss-Prot
Pfam Transglut_C UniProtKB/Swiss-Prot
  Transglut_core UniProtKB/Swiss-Prot
  Transglut_N UniProtKB/Swiss-Prot
PhenoGen Tgm1 PhenoGen
PIRSF TGM_EBP42 UniProtKB/Swiss-Prot
PROSITE TRANSGLUTAMINASES UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020136 RatGTEx
SMART TGc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49309 UniProtKB/Swiss-Prot
  SSF54001 UniProtKB/Swiss-Prot
  SSF81296 UniProtKB/Swiss-Prot
TIGR TC206700
UniProt A0A0B5AG38_RAT UniProtKB/TrEMBL
  A0A8I5ZX14 ENTREZGENE, UniProtKB/TrEMBL
  A6KH40 ENTREZGENE, UniProtKB/TrEMBL
  P23606 ENTREZGENE
  Q4QRA6 ENTREZGENE
  TGM1_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q4QRA6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-06-04 Tgm1  transglutaminase 1  Tgm1  transglutaminase 1, K polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-29 Tgm1  transglutaminase 1, K polypeptide  Tgm1  transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-02-02 Tgm1  transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)  Tgm1  transglutaminase 1, K polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Tgm1  transglutaminase 1, K polypeptide  Tgm1  transglutaminase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Tgm1  transglutaminase 1      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_protein putative protein has molecular weight of 90 kDa 61767