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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61838
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgm1
Name: transglutaminase 1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgm1decreases expressionISOTGM1 (Homo sapiens)6480464CTDTretinoin analog results in decreased expression of TGM1 mRNA; Tretinoin metabolite results in decreased expression of TGM1 mRNA; Tretinoin results in decreased expression of TGM1 mRNA; Tretinoin results in decreased expression of TGM1 proteinPMID:10953040 PMID:1318502 PMID:15982314 PMID:16985168 PMID:17147502 PMID:23830798 PMID:7505756
Tgm1increases expressionISOTGM1 (Homo sapiens)6480464CTDTretinoin results in increased expression of TGM1 proteinPMID:8396608
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