Vldlr (very low density lipoprotein receptor) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Vldlr (very low density lipoprotein receptor) Rattus norvegicus
Analyze
Symbol: Vldlr
Name: very low density lipoprotein receptor
RGD ID: 3963
Description: Predicted to enable several functions, including reelin receptor activity; very-low-density lipoprotein particle binding activity; and very-low-density lipoprotein particle receptor activity. Involved in several processes, including cellular response to glucose starvation; cellular response to insulin stimulus; and cellular response to lipopolysaccharide. Located in apical part of cell; cell surface; and perinuclear region of cytoplasm. Biomarker of focal segmental glomerulosclerosis and nephrotic syndrome. Human ortholog(s) of this gene implicated in Alzheimer's disease; cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 1; and dementia. Orthologous to human VLDLR (very low density lipoprotein receptor); PARTICIPATES IN altered Reelin signaling pathway; Reelin signaling pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: very low-density lipoprotein receptor; VLDL receptor; VLDL-R
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81234,239,769 - 234,272,150 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1234,240,121 - 234,272,154 (+)EnsemblGRCr8
mRatBN7.21224,813,539 - 224,850,400 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1224,814,377 - 224,845,920 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1233,244,716 - 233,276,159 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01240,174,828 - 240,206,271 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01232,995,566 - 233,027,009 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01245,236,819 - 245,273,688 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1245,237,736 - 245,269,205 (+)Ensemblrn6Rnor6.0
Rnor_5.01252,485,275 - 252,523,202 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41230,666,736 - 230,697,748 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1222,002,111 - 222,033,270 (+)NCBICelera
RGSC_v3.11230,830,758 - 230,861,771 (+)NCBI
RH 3.4 Map11610.4RGD
Cytogenetic Map1q52NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (EXP,ISO)
AM-251  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
ampicillin  (ISO)
androgen antagonist  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (EXP,ISO)
Butylparaben  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
casticin  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cycloheximide  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
enzacamene  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
fluoxetine  (EXP,ISO)
flutamide  (ISO)
folic acid  (ISO)
fonofos  (ISO)
formaldehyde  (ISO)
fructose  (ISO)
fulvestrant  (EXP)
furan  (EXP)
gamma-hexachlorocyclohexane  (ISO)
geldanamycin  (EXP)
gemcitabine  (ISO)
genistein  (EXP,ISO)
geraniol  (ISO)
haloperidol  (EXP)
herbimycin  (EXP)
hexaconazole  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
imidacloprid  (EXP)
indometacin  (EXP)
irinotecan  (EXP)
ketoconazole  (EXP)
L-methionine  (ISO)
lead diacetate  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (ISO)
methapyrilene  (EXP)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
mifepristone  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
ochratoxin A  (ISO)
olanzapine  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
prednisolone  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
prothioconazole  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
radicicol  (EXP)
rimonabant  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
streptozocin  (ISO)
succimer  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
Tesaglitazar  (EXP)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (EXP)
Tungsten carbide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vorinostat  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolae. Boucher P, etal., J Biol Chem 2002 May 3;277(18):15507-13. Epub 2002 Feb 19.
2. Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor. Chen SJ, etal., Mol Ther. 2000 Sep;2(3):256-61.
3. Role of the macrophage very-low-density lipoprotein receptor in atherosclerotic lesion development. Eck MV, etal., Atherosclerosis. 2005 Dec;183(2):230-7. Epub 2005 Jun 24.
4. Reelin signaling is impaired in autism. Fatemi SH, etal., Biol Psychiatry. 2005 Apr 1;57(7):777-87.
5. Chronic psychotropic drug treatment causes differential expression of Reelin signaling system in frontal cortex of rats. Fatemi SH, etal., Schizophr Res. 2009 Jun;111(1-3):138-52. Epub 2009 Apr 9.
6. Rat small intestine expresses the reelin-Disabled-1 signalling pathway. Garcia-Miranda P, etal., Exp Physiol. 2010 Apr;95(4):498-507. Epub 2009 Nov 27.
7. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
9. Protection from obesity in mice lacking the VLDL receptor. Goudriaan JR, etal., Arterioscler Thromb Vasc Biol. 2001 Sep;21(9):1488-93.
10. Dietary single cell protein reduces fatty liver in obese Zucker rats. Gudbrandsen OA, etal., Br J Nutr. 2008 Oct;100(4):776-85. Epub 2008 Mar 18.
11. VLDL receptor polymorphism, cognitive impairment, and dementia. Helbecque N, etal., Neurology 2001 May 8;56(9):1183-8.
12. Deficiency of the very low-density lipoprotein (VLDL) receptors in streptozotocin-induced diabetic rats: insulin dependency of the VLDL receptor. Iwasaki T, etal., Endocrinology. 2005 Aug;146(8):3286-94. Epub 2005 May 5.
13. Changes in cardiac lipid metabolism during sepsis: the essential role of very low-density lipoprotein receptors. Jia L, etal., Cardiovasc Res. 2006 Feb 1;69(2):545-55. Epub 2005 Dec 22.
14. Regulation of the very low density lipoprotein receptor by thyroid hormone in rat skeletal muscle. Jokinen EV, etal., J Biol Chem. 1994 Oct 21;269(42):26411-8.
15. The reelin signaling pathway: some recent developments. Jossin Y, etal., Cereb Cortex 2003 Jun;13(6):627-33.
16. Remnant lipoprotein particles are taken up into myocardium through VLDL receptor--a possible mechanism for cardiac fatty acid metabolism. Kamataki A, etal., Biochem Biophys Res Commun 2002 May 10;293(3):1007-13.
17. Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor. Kobayashi K, etal., J Biol Chem. 1996 Mar 22;271(12):6852-60.
18. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
19. Acquired VLDL receptor deficiency in experimental nephrosis. Liang K and Vaziri ND, Kidney Int. 1997 Jun;51(6):1761-5.
20. Role of secondary hyperparathyroidism in the genesis of hypertriglyceridemia and VLDL receptor deficiency in chronic renal failure. Liang K, etal., Kidney Int. 1998 Mar;53(3):626-30.
21. Genomic response of hypoxic Muller cells involves the very low density lipoprotein receptor as part of an angiogenic network. Loewen N, etal., Exp Eye Res. 2009 May;88(5):928-37. Epub 2009 Jan 8.
22. Localization of ApoER2, VLDLR and Dab1 in radial glia: groundwork for a new model of reelin action during cortical development. Luque JM, etal., Brain Res Dev Brain Res 2003 Feb 16;140(2):195-203.
23. Regulation of very-low-density lipoprotein receptor in hypertrophic rat heart. Masuzaki H, etal., Circ Res. 1996 Jan;78(1):8-14.
24. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
25. A variant very low density lipoprotein receptor lacking 84 base pairs of O-linked sugar domain in the human brain myelin. Nakamura Y, etal., Brain Res 1998 May 18;793(1-2):47-53.
26. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
27. Genetic association of the very low density lipoprotein (VLDL) receptor gene with sporadic Alzheimer's disease. Okuizumi K, etal., Nat Genet 1995 Oct;11(2):207-9.
28. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
29. Diabetic and dyslipidaemic morbidly obese exhibit more liver alterations compared with healthy morbidly obese. Pardina E, etal., BBA Clin. 2016 Jan 8;5:54-65. doi: 10.1016/j.bbacli.2015.12.002. eCollection 2016 Jun.
30. Maternal Thyroid Hormone before the Onset of Fetal Thyroid Function Regulates Reelin and Downstream Signaling Cascade Affecting Neocortical Neuronal Migration. Pathak A, etal., Cereb Cortex. 2010 Apr 5.
31. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
32. GOA pipeline RGD automated data pipeline
33. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
34. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
35. Effect of diet on adipose tissue and skeletal muscle VLDL receptor and LPL: implications for obesity and hyperlipidemia. Roberts CK, etal., Atherosclerosis. 2002 Mar;161(1):133-41.
36. Down-regulation of lipoprotein lipase and VLDL receptor in rats with focal glomerulosclerosis. Sato T, etal., Kidney Int. 2002 Jan;61(1):157-62.
37. Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus. Shakib K, etal., Proteomics. 2005 Jul;5(11):2819-38.
38. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
39. Rat neurological disease creeping is caused by a mutation in the reelin gene. Yokoi N, etal., Brain Res Mol Brain Res 2003 Apr 10;112(1-2):1-7.
40. Glucose deprivation accelerates VLDL receptor-mediated TG-rich lipoprotein uptake by AMPK activation in skeletal muscle cells. Zenimaru Y, etal., Biochem Biophys Res Commun. 2008 Apr 11;368(3):716-22. Epub 2008 Feb 8.
Additional References at PubMed
PMID:8083232   PMID:10571240   PMID:12526740   PMID:15082773   PMID:15950758   PMID:18778775   PMID:20711475   PMID:22429478   PMID:23382219   PMID:23990472   PMID:25644714   PMID:26751967  


Genomics

Comparative Map Data
Vldlr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81234,239,769 - 234,272,150 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1234,240,121 - 234,272,154 (+)EnsemblGRCr8
mRatBN7.21224,813,539 - 224,850,400 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1224,814,377 - 224,845,920 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1233,244,716 - 233,276,159 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01240,174,828 - 240,206,271 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01232,995,566 - 233,027,009 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01245,236,819 - 245,273,688 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1245,237,736 - 245,269,205 (+)Ensemblrn6Rnor6.0
Rnor_5.01252,485,275 - 252,523,202 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41230,666,736 - 230,697,748 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1222,002,111 - 222,033,270 (+)NCBICelera
RGSC_v3.11230,830,758 - 230,861,771 (+)NCBI
RH 3.4 Map11610.4RGD
Cytogenetic Map1q52NCBI
VLDLR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3892,621,787 - 2,660,056 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl92,621,182 - 2,660,056 (+)Ensemblhg38GRCh38
GRCh3792,621,787 - 2,660,056 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3692,611,793 - 2,644,485 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3492,611,802 - 2,644,478NCBI
Celera92,540,058 - 2,572,749 (+)NCBICelera
Cytogenetic Map9p24.2NCBI
HuRef92,576,882 - 2,609,583 (+)NCBIHuRef
CHM1_192,622,136 - 2,654,832 (+)NCBICHM1_1
T2T-CHM13v2.092,624,554 - 2,662,816 (+)NCBIT2T-CHM13v2.0
Vldlr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391927,190,070 - 27,231,631 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1927,193,884 - 27,231,631 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381927,216,480 - 27,254,231 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1927,216,484 - 27,254,231 (+)Ensemblmm10GRCm38
MGSCv371927,291,510 - 27,328,721 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361927,284,529 - 27,316,717 (+)NCBIMGSCv36mm8
Celera1928,001,119 - 28,038,314 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1921.77NCBI
Vldlr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554347,013,092 - 7,050,103 (+)Ensembl
ChiLan1.0NW_0049554347,013,092 - 7,050,103 (+)NCBIChiLan1.0ChiLan1.0
VLDLR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211121,929,854 - 121,963,106 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19121,935,797 - 121,969,049 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v092,428,639 - 2,463,796 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.192,621,325 - 2,653,980 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl92,621,199 - 2,653,980 (+)EnsemblpanPan2panpan1.1
VLDLR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1191,242,010 - 91,277,030 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl191,241,509 - 91,272,495 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha191,709,985 - 91,740,404 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0191,786,552 - 91,821,587 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl191,786,012 - 91,818,969 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1191,433,922 - 91,464,358 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0191,145,967 - 91,176,393 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0191,920,678 - 91,951,114 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Vldlr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947138,732,746 - 138,766,426 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365032,405,689 - 2,440,502 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365032,407,040 - 2,440,366 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VLDLR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1219,173,507 - 219,210,343 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11219,178,501 - 219,210,332 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21245,001,226 - 245,032,858 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VLDLR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11276,900,551 - 76,933,601 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1276,899,189 - 76,933,584 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603865,238,161 - 65,273,396 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vldlr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247367,280,490 - 7,316,946 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247367,280,478 - 7,316,897 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Vldlr
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1227,230,627 - 27,262,383 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Vldlr
214 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:106
Count of miRNA genes:66
Interacting mature miRNAs:85
Transcripts:ENSRNOT00000035814
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8693637Alc29Alcohol consumption QTL 292.70.258drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367243666627Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1207243873252243873Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1210980612255980612Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1223964326248681945Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1226175591270518180Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1205233991267096252Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1218829748263829748Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1193964073238964073Rat
8693661Alc34Alcohol consumption QTL 342.20.611drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367238041033Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1210980612255980612Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1194575422239575422Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1193400541238400541Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1233480549270108840Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1200449456256003563Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1233480549270108840Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1207163993269633915Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1210980612255980612Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1223134011262090599Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1210980612255980612Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1207243873252243873Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1209203273254203273Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1202543537247543537Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1225108840270108840Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1228180370266453608Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1205674651250674651Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1207243873252243873Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1208479811269633915Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1224633915269633915Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1232312773270518180Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1212738576257738576Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1188241285250779312Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1208798288253798288Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1228180243255849249Rat
1331790Bp201Blood pressure QTL 2013.127arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1221820316234540296Rat
1300168Bp170Blood pressure QTL 1702.76arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1192995199237995199Rat
61403Niddm4Non-insulin dependent diabetes mellitus QTL 4blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1201464383246464383Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1203675682248675682Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1205674651250674651Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1210980612255980612Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1210980612255980612Rat
7387289Uae45Urinary albumin excretion QTL 452.860.0021urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1233204160270518180Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1193400541238400541Rat
634340Hcar5Hepatocarcinoma resistance QTL 58liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1223964326236074012Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1207099883252099883Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1210980612255980612Rat
8693618Alc25Alcohol consumption QTL 2530.28drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1217412367238041033Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1191260175236260175Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1226175591270518180Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233349180270518180Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1210980612255980612Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1228174566270518180Rat

Markers in Region
WI-18746  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21224,845,372 - 224,845,521 (+)MAPPERmRatBN7.2
Rnor_6.01245,268,658 - 245,268,806NCBIRnor6.0
Rnor_5.01252,518,172 - 252,518,320UniSTSRnor5.0
RGSC_v3.41230,697,669 - 230,697,817UniSTSRGSC3.4
Celera1222,032,723 - 222,032,871UniSTS
Cytogenetic Map1q51UniSTS
09.MMHAP31FLC3.seq  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21224,842,817 - 224,842,968 (+)MAPPERmRatBN7.2
Rnor_6.01245,266,103 - 245,266,253NCBIRnor6.0
Rnor_5.01252,515,617 - 252,515,767UniSTSRnor5.0
RGSC_v3.41230,695,114 - 230,695,264UniSTSRGSC3.4
Celera1222,030,168 - 222,030,318UniSTS
Cytogenetic Map1q51UniSTS
RH94526  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81234,271,540 - 234,271,646 (+)Marker Load Pipeline
mRatBN7.21224,845,310 - 224,845,416 (+)MAPPERmRatBN7.2
Rnor_6.01245,268,596 - 245,268,701NCBIRnor6.0
Rnor_5.01252,518,110 - 252,518,215UniSTSRnor5.0
RGSC_v3.41230,697,607 - 230,697,712UniSTSRGSC3.4
Celera1222,032,661 - 222,032,766UniSTS
RH 3.4 Map11610.4UniSTS
Cytogenetic Map1q51UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 84 59 6 348 184 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000035814   ⟹   ENSRNOP00000036229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1234,240,121 - 234,272,147 (+)Ensembl
mRatBN7.2 Ensembl1224,814,377 - 224,845,914 (+)Ensembl
Rnor_6.0 Ensembl1245,237,736 - 245,269,205 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106818   ⟹   ENSRNOP00000091849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1234,240,239 - 234,272,154 (+)Ensembl
mRatBN7.2 Ensembl1224,814,571 - 224,845,920 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000149801   ⟹   ENSRNOP00000105813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1234,240,239 - 234,272,154 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000167761   ⟹   ENSRNOP00000107234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1234,240,121 - 234,272,147 (+)Ensembl
RefSeq Acc Id: NM_013155   ⟹   NP_037287
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81234,240,686 - 234,272,150 (+)NCBI
mRatBN7.21224,814,456 - 224,845,920 (+)NCBI
Rnor_6.01245,237,736 - 245,269,205 (+)NCBI
Rnor_5.01252,485,275 - 252,523,202 (+)NCBI
RGSC_v3.41230,666,736 - 230,697,748 (+)RGD
Celera1222,002,111 - 222,033,270 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231197   ⟹   XP_006231259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81234,239,769 - 234,272,150 (+)NCBI
mRatBN7.21224,813,539 - 224,850,400 (+)NCBI
Rnor_6.01245,236,819 - 245,273,688 (+)NCBI
Rnor_5.01252,485,275 - 252,523,202 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231198   ⟹   XP_006231260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81234,240,251 - 234,272,150 (+)NCBI
mRatBN7.21224,814,022 - 224,850,400 (+)NCBI
Rnor_6.01245,237,281 - 245,273,688 (+)NCBI
Rnor_5.01252,485,275 - 252,523,202 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017588829   ⟹   XP_017444318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81234,240,529 - 234,272,150 (+)NCBI
mRatBN7.21224,814,298 - 224,850,400 (+)NCBI
Rnor_6.01245,237,823 - 245,273,688 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017588830   ⟹   XP_017444319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81234,240,531 - 234,272,150 (+)NCBI
mRatBN7.21224,814,300 - 224,850,400 (+)NCBI
Rnor_6.01245,237,823 - 245,273,688 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039102103   ⟹   XP_038958031
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81234,240,167 - 234,272,150 (+)NCBI
mRatBN7.21224,813,940 - 224,850,400 (+)NCBI
RefSeq Acc Id: XM_063282122   ⟹   XP_063138192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81234,240,227 - 234,272,150 (+)NCBI
RefSeq Acc Id: XM_063282143   ⟹   XP_063138213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81234,239,769 - 234,272,150 (+)NCBI
RefSeq Acc Id: XM_063282154   ⟹   XP_063138224
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81234,240,238 - 234,272,150 (+)NCBI
RefSeq Acc Id: NP_037287   ⟸   NM_013155
- Peptide Label: precursor
- UniProtKB: P98166 (UniProtKB/Swiss-Prot),   F1LPV2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231259   ⟸   XM_006231197
- Peptide Label: isoform X1
- UniProtKB: P98166 (UniProtKB/Swiss-Prot),   F1LPV2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231260   ⟸   XM_006231198
- Peptide Label: isoform X1
- UniProtKB: P98166 (UniProtKB/Swiss-Prot),   F1LPV2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444318   ⟸   XM_017588829
- Peptide Label: isoform X3
- UniProtKB: P98166 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017444319   ⟸   XM_017588830
- Peptide Label: isoform X4
- UniProtKB: P98166 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000036229   ⟸   ENSRNOT00000035814
RefSeq Acc Id: XP_038958031   ⟸   XM_039102103
- Peptide Label: isoform X1
- UniProtKB: P98166 (UniProtKB/Swiss-Prot),   F1LPV2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000091849   ⟸   ENSRNOT00000106818
RefSeq Acc Id: XP_063138213   ⟸   XM_063282143
- Peptide Label: isoform X2
- UniProtKB: P98166 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063138192   ⟸   XM_063282122
- Peptide Label: isoform X1
- UniProtKB: P98166 (UniProtKB/Swiss-Prot),   F1LPV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138224   ⟸   XM_063282154
- Peptide Label: isoform X2
- UniProtKB: P98166 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000105813   ⟸   ENSRNOT00000149801
Ensembl Acc Id: ENSRNOP00000107234   ⟸   ENSRNOT00000167761
Protein Domains
EGF-like   LDL-receptor class A

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P98166-F1-model_v2 AlphaFold P98166 1-873 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690836
Promoter ID:EPDNEW_R1361
Type:initiation region
Name:Vldlr_2
Description:very low density lipoprotein receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R1362  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01245,237,719 - 245,237,779EPDNEW
RGD ID:13690838
Promoter ID:EPDNEW_R1362
Type:initiation region
Name:Vldlr_1
Description:very low density lipoprotein receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R1361  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01245,237,862 - 245,237,922EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3963 AgrOrtholog
BioCyc Gene G2FUF-56030 BioCyc
Ensembl Genes ENSRNOG00000027491 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000035814 ENTREZGENE
  ENSRNOT00000149801 ENTREZGENE
  ENSRNOT00000167761 ENTREZGENE
Gene3D-CATH 2.120.10.30 UniProtKB/Swiss-Prot
  4.10.400.10 UniProtKB/Swiss-Prot
  Laminin UniProtKB/Swiss-Prot
InterPro 6-blade_b-propeller_TolB-like UniProtKB/Swiss-Prot
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot
  EGF-like_dom UniProtKB/Swiss-Prot
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/Swiss-Prot
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot
  Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot
  LDL_receptor-like_sf UniProtKB/Swiss-Prot
  LDLR-related UniProtKB/Swiss-Prot
  LDLR_class-A_CS UniProtKB/Swiss-Prot
  LDLR_classB_rpt UniProtKB/Swiss-Prot
  LDrepeatLR_classA_rpt UniProtKB/Swiss-Prot
  NOTCH1_EGF-like UniProtKB/Swiss-Prot
NCBI Gene 25696 ENTREZGENE
PANTHER LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED UniProtKB/Swiss-Prot
  LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED UniProtKB/Swiss-Prot
Pfam EGF_CA UniProtKB/Swiss-Prot
  FXa_inhibition UniProtKB/Swiss-Prot
  Ldl_recept_a UniProtKB/Swiss-Prot
  Ldl_recept_b UniProtKB/Swiss-Prot
PhenoGen Vldlr PhenoGen
PRINTS LDLRECEPTOR UniProtKB/Swiss-Prot
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
  LDLRA_1 UniProtKB/Swiss-Prot
  LDLRA_2 UniProtKB/Swiss-Prot
  LDLRB UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000027491 RatGTEx
SMART EGF UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
  LDLa UniProtKB/Swiss-Prot
  SM00135 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57184 UniProtKB/Swiss-Prot
  SSF57424 UniProtKB/Swiss-Prot
  YWTD domain UniProtKB/Swiss-Prot
TIGR TC230870
UniProt A0A8I6ACI8_RAT UniProtKB/TrEMBL
  A0ABK0L6Z1_RAT UniProtKB/TrEMBL
  A0ABK0LR98_RAT UniProtKB/TrEMBL
  A6I0T1_RAT UniProtKB/TrEMBL
  F1LPV2 ENTREZGENE, UniProtKB/TrEMBL
  P98166 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Vldlr  Very low density lipoprotein receptor      Symbol and Name status set to approved 70586 APPROVED