VLDLR (very low density lipoprotein receptor)

Gene: VLDLR (very low density lipoprotein receptor) Canis lupus familiaris

Analyze

Symbol:

VLDLR

Name:

very low density lipoprotein receptor

RGD ID:

12386022

Description:

ENCODES a protein that exhibits apolipoprotein binding (inferred); calcium ion binding (inferred); calcium-dependent protein binding (inferred); INVOLVED IN cellular response to glucose starvation (ortholog); cellular response to hypoxia (ortholog); cellular response to insulin stimulus (ortholog); PARTICIPATES IN altered Reelin signaling pathway; Reelin signaling pathway; ASSOCIATED WITH cerebellar ataxia, mental retardation and dysequlibrium syndrome; age related macular degeneration 1 (ortholog); Alzheimer's disease (ortholog); FOUND IN apical part of cell (ortholog); cell surface (ortholog); glutamatergic synapse (ortholog)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

very low-density lipoprotein receptor

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	91,242,010 - 91,277,030 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	91,241,509 - 91,272,495 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	91,709,985 - 91,740,404 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	91,786,552 - 91,821,587 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	91,786,012 - 91,818,969 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	91,433,922 - 91,464,358 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	91,145,967 - 91,176,393 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	91,920,678 - 91,951,114 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

amenorrhea (ISO)

arteriosclerosis (ISO)

autistic disorder (ISO)

Cardiomegaly (ISO)

cerebellar ataxia, mental retardation and dysequlibrium syndrome (IAGP,ISO)

Cerebellar Ataxia, Mental Retardation, and Dysequilibrium Syndrome 1 (ISO)

cerebellar hypoplasia (ISO)

chromosome 9p deletion syndrome (ISO)

dementia (ISO)

Experimental Diabetes Mellitus (ISO)

familial hyperlipidemia (ISO)

focal segmental glomerulosclerosis (ISO)

genetic disease (ISO)

Hypercholesterolemia (ISO)

Hypertriglyceridemia (ISO)

intellectual disability (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

microcephaly (ISO)

nephrotic syndrome (ISO)

Nervous System Malformations (ISO)

obesity (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Cellular Component

apical part of cell (ISO)

cell surface (ISO)

extracellular space (IEA)

glutamatergic synapse (ISO)

membrane (IEA)

perinuclear region of cytoplasm (ISO)

plasma membrane (IEA)

receptor complex (IEA)

synapse (ISO)

Molecular Function

apolipoprotein binding (IEA)

calcium ion binding (IEA)

calcium-dependent protein binding (IEA)

cargo receptor activity (IEA)

protein binding (ISO)

reelin receptor activity (IEA)

very-low-density lipoprotein particle binding (IEA)

very-low-density lipoprotein particle receptor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

altered Reelin signaling pathway (ISO)

Reelin signaling pathway (ISO)

References

Additional References at PubMed

PMID:15233990	PMID:22301074	PMID:25668033

Genomics

Comparative Map Data

VLDLR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	91,242,010 - 91,277,030 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	91,241,509 - 91,272,495 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	91,709,985 - 91,740,404 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	91,786,552 - 91,821,587 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	91,786,012 - 91,818,969 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	91,433,922 - 91,464,358 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	91,145,967 - 91,176,393 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	91,920,678 - 91,951,114 (+)	NCBI		UU_Cfam_GSD_1.0

VLDLR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	2,621,787 - 2,660,056 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	2,621,182 - 2,660,056 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	2,621,787 - 2,660,056 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	2,611,793 - 2,644,485 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	2,611,802 - 2,644,478	NCBI
Celera	9	2,540,058 - 2,572,749 (+)	NCBI		Celera
Cytogenetic Map	9	p24.2	NCBI
HuRef	9	2,576,882 - 2,609,583 (+)	NCBI		HuRef
CHM1_1	9	2,622,136 - 2,654,832 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	2,624,554 - 2,662,816 (+)	NCBI		T2T-CHM13v2.0

Vldlr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	27,190,070 - 27,231,631 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	27,193,884 - 27,231,631 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	27,216,480 - 27,254,231 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	27,216,484 - 27,254,231 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	27,291,510 - 27,328,721 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	27,284,529 - 27,316,717 (+)	NCBI		MGSCv36	mm8
Celera	19	28,001,119 - 28,038,314 (+)	NCBI		Celera
Cytogenetic Map	19	C1	NCBI
cM Map	19	21.77	NCBI

Vldlr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	234,239,769 - 234,272,150 (+)	NCBI		GRCr8
mRatBN7.2	1	224,813,539 - 224,850,400 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	224,814,377 - 224,845,920 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	233,244,716 - 233,276,159 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	240,174,828 - 240,206,271 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	232,995,566 - 233,027,009 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	245,236,819 - 245,273,688 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	245,237,736 - 245,269,205 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	252,485,275 - 252,523,202 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	230,666,736 - 230,697,748 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	230,830,758 - 230,861,771 (+)	NCBI
Celera	1	222,002,111 - 222,033,270 (+)	NCBI		Celera
RH 3.4 Map	1	1610.4	RGD
Cytogenetic Map	1	q52	NCBI

Vldlr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955434	7,013,092 - 7,050,103 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955434	7,013,092 - 7,050,103 (+)	NCBI	ChiLan1.0	ChiLan1.0

VLDLR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	121,929,854 - 121,963,106 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	121,935,797 - 121,969,049 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	2,428,639 - 2,463,796 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	2,621,325 - 2,653,980 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	2,621,199 - 2,653,980 (+)	Ensembl	panpan1.1		panPan2

Vldlr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	138,732,746 - 138,766,426 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936503	2,405,689 - 2,440,502 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936503	2,407,040 - 2,440,366 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VLDLR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	219,173,507 - 219,210,343 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	219,178,501 - 219,210,332 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	245,001,226 - 245,032,858 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

VLDLR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	76,900,551 - 76,933,601 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	76,899,189 - 76,933,584 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	65,238,161 - 65,273,396 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Vldlr
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	7,280,490 - 7,316,946 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624736	7,280,478 - 7,316,897 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in VLDLR
461 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	2	5	10		3			3	8		5
Low	3		12	6	3	6	6	3	4	1	5	6
Below cutoff										7

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001286978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003432618	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005615907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022419275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038653490	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038653491	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038653492	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY514784	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000037573 ⟹ ENSCAFP00000033110

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	1	91,241,509 - 91,272,495 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000037581 ⟹ ENSCAFP00000033118

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	1	91,241,509 - 91,272,495 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000064967 ⟹ ENSCAFP00000044376

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	1	91,241,509 - 91,272,495 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845004150 ⟹ ENSCAFP00845003320

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	1	91,786,012 - 91,817,056 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845004185 ⟹ ENSCAFP00845003345

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	1	91,786,012 - 91,817,056 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845004212 ⟹ ENSCAFP00845003367

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	1	91,786,536 - 91,818,969 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845004233 ⟹ ENSCAFP00845003381

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	1	91,786,536 - 91,818,969 (+)	Ensembl

RefSeq Acc Id:

NM_001286978 ⟹ NP_001273907

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	1	91,242,066 - 91,272,495 (+)	NCBI
Dog10K_Boxer_Tasha	1	91,709,985 - 91,740,404 (+)	NCBI
ROS_Cfam_1.0	1	91,786,608 - 91,817,052 (+)	NCBI
UMICH_Zoey_3.1	1	91,433,922 - 91,464,358 (+)	NCBI
UNSW_CanFamBas_1.0	1	91,145,967 - 91,176,393 (+)	NCBI
UU_Cfam_GSD_1.0	1	91,920,678 - 91,951,114 (+)	NCBI

Sequence:

show sequence

GCGGGCACCATGGGCACGTCCGCGCGCTGGGCGCTCTGGCTGCTGCTCGCGCTGTGCTGGGCGC
CCCGGGAGAGCCGCGCCACCGGAGCGGGAAGAAAAGCCAAATGTGAACCCTCCCAATTCCAGTG
CACAAATGGCCGCTGTATTACATTGCTGTGGAAATGCGACGGGGATGAAGACTGCGCTGATGGC
AGTGACGAAAAGAACTGTGTAAAGAAGACGTGTGCAGAGTCTGACTTTGTGTGCAACAATGGCC
AGTGCGTCCCCAACCGGTGGCAGTGTGACGGGGATCCTGACTGTGAAGATGGTTCTGATGAAAA
CCCAGAACAGTGCCATATGAGAACATGCCGCATAAATGAAATCAGCTGTGGCGCCCGTTCTACT
CAGTGTATCCCAGTGTCCTGGAGGTGTGATGGTGAAAATGATTGTGACAGTGGAGAAGATGAAG
AAAACTGTGGCAACATCACATGCAGCCCGGACGAGTTCACCTGCTCCAGCGGCCGTTGCATCTC
CAGGAACTTCGTCTGCAATGGCCAGGACGACTGCAGTGACGGCAGCGACGAGCTGGACTGCGCG
CCCCCCACGTGCGGCGAGCATGAGTTCCAGTGCAGCACCTCTTCCTGCATCCCCCTGAGCTGGG
TATGCGACGATGACGCCGACTGCTCCGACCAGTCAGATGAGTCCCTGGAGCAGTGTGGCCGCCA
GCCCGTGATGCACACCAAGTGCCCAGCCAGCGAGACCCAGTGCGGCTCAGGCGAGTGCATCCAC
AAGAAGTGGCGCTGCGATGGGGACCCCGACTGCAAAGACGGCAGCGACGAGGTCAACTGTCCTT
CGAGAACCTGCCGGCCTGACCAGTTTGAGTGTGAGGACGGGAGCTGCATCCATGGCAGCAGGCA
GTGCAACGGTATCAGGGACTGTGTGGACGGCTCGGATGAAGTCAACTGCAAGAACGTCAATCAG
TGCTTGGGCCCTGGAAAGTTCAAGTGCAGAAGTGGGGAGTGCATAGATATCGGTAAAGTATGTA
ACCAGGAGCAGGACTGCAGGGACTGGAGTGACGAACCCCTGAAAGAATGTCACGTAAATGAATG
CTTGGTTAATAATGGTGGCTGTTCGCACATCTGCAAAGACCTAGTTATAGGCTATGAATGTGAC
TGCGCAGCTGGGTTTGAACTGATAGATAAGAAAATTTGTGGAGATATTGACGAATGCCAAAATC
CAGGAATCTGCAGCCAAATTTGTATCAACTTAAAAGGCGGTTACAAGTGTGAATGTAGTCGGGG
CTATCAGATGGATCTTGCCACCGGCGTGTGCAAGGCAGTAGGCAAAGAGCCAAGTCTGATCTTC
ACAAATCGAAGAGACATCCGGAAGATTGGCTTGGAGAGGAAAGAATATATTCAACTAGTTGAAC
AGCTAAGAAACACTGTAGCTCTTGATGCAGACATTGCAGCTCAGAAACTGTTCTGGGCTGATCT
GAGCCAAAAGGCCATCTTCAGTGCCTCAATTGATGACAAGGTTGGTAGACATGTTAAAATGATC
GACAATGTCTATAATCCTGCAGCCATTGCTGTTGATTGGGTGTACAAGACCATCTACTGGACTG
ATGTGGCTTCTAAGACTATTTCAGTAGCTACCCTAGATGGGACCAGAAGGAAGTTCCTGTTTAA
CTCTGACTTGCGGGAGCCTGCCTCCATAGCTGTGGATCCACTCTCTGGGTTTGTGTACTGGTCA
GACTGGGGAGAACCAGCTAAAATAGAAAAAGCAGGAATGAATGGATTTGATAGGCGGCCACTTG
TGACAGTGGACATCCAATGGCCTAATGGAATTACACTTGACCTTATAAAGAGTCGCCTCTACTG
GCTTGACTCCAAGTTGCACATGTTGTCCAGCGTGGACTTAAATGGCCAAGACCGTAGGATTGTC
CTTAAATCTCTGGAGTTCCTAGCTCATCCTCTGGCGCTAACCATATTTGAGGATCGTGTCTACT
GGATAGATGGGGAAAATGAAGCAGTCTACGGTGCCAATAAATTCACTGGATCAGAGCTGGCCAC
GCTAGTAAACAACCTTAATGATGCCCAAGACATCATTGTCTATCACGAACTCGTCCAGCCGTCA
GGTAAAAACTGGTGTGAAGAGGACATGCAGAATGGAGGCTGTGAATATCTGTGCCTGCCAGCAC
CACAAATCAACGATCACTCTCCAAAATACACGTGTTCCTGTCCCAATGGGTACACTCTAGAGGC
AAACGGCCGGGAGTGCCACAGTACTGCAACTACTCTGACTTACAGTGAGACAAAAGATATCCAC
ACAACAGAAATTCCTCCAACTAGTGGACTAGTTCCCAGAGGGATCAATGTGACCACAGCAGTAT
CGGAGGCCACTGTTCCCCCAAAAGGCACTTCTGCTGCCTGGGCCATCCTTCCTCTCTTGCTCTT
AGCAATGGCAGCGGTAGGTGGCTACTTGATGTGGCGGAATTGGCAGCACAAGAACATGAAAAGC
ATGAACTTTGACAATCCTGTGTACTTGAAGACTACTGAAGAGGACCTGTCCATAGACATTGGTA
GACACAGTGCTTCTGTTGGACACACGTACCCCGCAATATCAGTTGTAAGCACAGATGATGACCT
AGCTTGACTTCAGAGACAAGCCTTGACCTTTGAGGTCTAAACCAATAACCCTCCACTTCGAAAT
GGTAACCGAGCCAGCGCCTGAAGTCTTTCTTCCTTCAGTCTGGAAGAACATCAAGATATCTTTA
CTTGGATCAAGCTTGTATACTTGATCATTTTTATATTACTTTTGTAAATATTCCTATCCACATT
CTACTTCAGCTTTGGATGTGGTTACCAAGTATCTAATCCTTGAGTTTCTAGACAGTATTGCCAC
ATCTGGCCAAATATGCACTTTCCCTAGAAAGCCATATTCCAGCAATGAAACTTGTGCTATAGTG
TATACCACCTGTACATACATTGTATAGGCCATCTGTAAATATCCCAGAGAACAATCACTATTCT
TAAGCACTTTGAAAATATTTCTATGTAAATTATTGTAAACTTTTTCAATGGTTGGGACAATGGC
AATAGGATAAAACGGGTTACTAAGATGAAATTGCCAAAAAAATTTGTAAACTAATTTTGTACGT
ATGAATGAAATCTTTGACCTCAGTGGAGGTTTGCAAAGACTGAGTATTCAAACTACTGTACATT
TTTTTTTCAAGTGCTAAAACAATTAAACCAAGCAGCTTAA

hide sequence

RefSeq Acc Id:

XM_038653490 ⟹ XP_038509418

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	91,786,552 - 91,821,587 (+)	NCBI

RefSeq Acc Id:

XM_038653491 ⟹ XP_038509419

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	91,786,552 - 91,821,587 (+)	NCBI

RefSeq Acc Id:

XM_038653492 ⟹ XP_038509420

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	91,786,552 - 91,821,587 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001273907	(Get FASTA)	NCBI Sequence Viewer
	XP_038509418	(Get FASTA)	NCBI Sequence Viewer
	XP_038509419	(Get FASTA)	NCBI Sequence Viewer
	XP_038509420	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAT47480	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000033110.4
	ENSCAFP00000033118.4
	ENSCAFP00000044376.2
	ENSCAFP00000071288.1
	ENSCAFP00000074484.1
	ENSCAFP00030019671.1
	ENSCAFP00030019788.1
	ENSCAFP00030019898.1
	ENSCAFP00030020018.1
	ENSCAFP00040005269.1
	ENSCAFP00040005312.1
	ENSCAFP00040005345.1
	ENSCAFP00040005394.1
	ENSCAFP00040005537.1
	ENSCAFP00040005633.1
	ENSCAFP00845003320
	ENSCAFP00845003320.1
	ENSCAFP00845003345.1
	ENSCAFP00845003367
	ENSCAFP00845003367.1
	ENSCAFP00845003381
	ENSCAFP00845003381.1

RefSeq Acc Id:	NP_001273907 ⟸ NM_001286978
- Peptide Label:	precursor
- UniProtKB:	A0A8C0N5Z3 (UniProtKB/TrEMBL), A0A8I3RQN7 (UniProtKB/TrEMBL), A0A8P0TU47 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGTSARWALWLLLALCWAPRESRATGAGRKAKCEPSQFQCTNGRCITLLWKCDGDEDCADGSDE KNCVKKTCAESDFVCNNGQCVPNRWQCDGDPDCEDGSDENPEQCHMRTCRINEISCGARSTQCI PVSWRCDGENDCDSGEDEENCGNITCSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPT CGEHEFQCSTSSCIPLSWVCDDDADCSDQSDESLEQCGRQPVMHTKCPASETQCGSGECIHKKW RCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLG PGKFKCRSGECIDIGKVCNQEQDCRDWSDEPLKECHVNECLVNNGGCSHICKDLVIGYECDCAA GFELIDKKICGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNR RDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNV YNPAAIAVDWVYKTIYWTDVASKTISVATLDGTRRKFLFNSDLREPASIAVDPLSGFVYWSDWG EPAKIEKAGMNGFDRRPLVTVDIQWPNGITLDLIKSRLYWLDSKLHMLSSVDLNGQDRRIVLKS LEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGSELATLVNNLNDAQDIIVYHELVQPSGKN WCEEDMQNGGCEYLCLPAPQINDHSPKYTCSCPNGYTLEANGRECHSTATTLTYSETKDIHTTE IPPTSGLVPRGINVTTAVSEATVPPKGTSAAWAILPLLLLAMAAVGGYLMWRNWQHKNMKSMNF DNPVYLKTTEEDLSIDIGRHSASVGHTYPAISVVSTDDDLA hide sequence

RefSeq Acc Id:

ENSCAFP00000044376 ⟸ ENSCAFT00000064967

RefSeq Acc Id:

ENSCAFP00000033118 ⟸ ENSCAFT00000037581

RefSeq Acc Id:

ENSCAFP00000033110 ⟸ ENSCAFT00000037573

RefSeq Acc Id:	XP_038509418 ⟸ XM_038653490
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0LX46 (UniProtKB/TrEMBL), A0A8C0QCS9 (UniProtKB/TrEMBL), A0A8C0LSZ2 (UniProtKB/TrEMBL), A0A8I3MFA4 (UniProtKB/TrEMBL), A0A8P0TP72 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038509419 ⟸ XM_038653491
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0N420 (UniProtKB/TrEMBL), A0A8C0N8P3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038509420 ⟸ XM_038653492
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I3MSV0 (UniProtKB/TrEMBL), A0A8P0NUR6 (UniProtKB/TrEMBL), A0A8I3MF94 (UniProtKB/TrEMBL), A0A8P0NMC0 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845003367 ⟸ ENSCAFT00845004212

RefSeq Acc Id:

ENSCAFP00845003320 ⟸ ENSCAFT00845004150

RefSeq Acc Id:

ENSCAFP00845003345 ⟸ ENSCAFT00845004185

RefSeq Acc Id:

ENSCAFP00845003381 ⟸ ENSCAFT00845004233

Protein Domains

EGF-like

Promoters

RGD ID:

13682100

Promoter ID:

EPDNEW_C169

Type:

multiple initiation site

Name:

VLDLR_1

Description:

very low density lipoprotein receptor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	1	91,242,020 - 91,242,080	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000002028	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030012132	UniProtKB/TrEMBL
	ENSCAFG00040003163	UniProtKB/TrEMBL
	ENSCAFG00845002345	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000037573.5	UniProtKB/TrEMBL
	ENSCAFT00000037581.4	UniProtKB/TrEMBL
	ENSCAFT00000064967.2	UniProtKB/TrEMBL
	ENSCAFT00000100014.1	UniProtKB/TrEMBL
	ENSCAFT00000107654.1	UniProtKB/TrEMBL
	ENSCAFT00030022551.1	UniProtKB/TrEMBL
	ENSCAFT00030022677.1	UniProtKB/TrEMBL
	ENSCAFT00030022804.1	UniProtKB/TrEMBL
	ENSCAFT00030022947.1	UniProtKB/TrEMBL
	ENSCAFT00040006104.1	UniProtKB/TrEMBL
	ENSCAFT00040006150.1	UniProtKB/TrEMBL
	ENSCAFT00040006185.1	UniProtKB/TrEMBL
	ENSCAFT00040006238.1	UniProtKB/TrEMBL
	ENSCAFT00040006397.1	UniProtKB/TrEMBL
	ENSCAFT00040006515.1	UniProtKB/TrEMBL
	ENSCAFT00845004150	ENTREZGENE
	ENSCAFT00845004150.1	UniProtKB/TrEMBL
	ENSCAFT00845004185.1	UniProtKB/TrEMBL
	ENSCAFT00845004212	ENTREZGENE
	ENSCAFT00845004212.1	UniProtKB/TrEMBL
	ENSCAFT00845004233	ENTREZGENE
	ENSCAFT00845004233.1	UniProtKB/TrEMBL
Gene3D-CATH	2.120.10.30	UniProtKB/TrEMBL
	4.10.400.10	UniProtKB/TrEMBL
	Laminin	UniProtKB/TrEMBL
InterPro	6-blade_b-propeller_TolB-like	UniProtKB/TrEMBL
	EGF-like_Ca-bd_dom	UniProtKB/TrEMBL
	EGF-like_dom	UniProtKB/TrEMBL
	EGF-type_Asp/Asn_hydroxyl_site	UniProtKB/TrEMBL
	EGF_Ca-bd_CS	UniProtKB/TrEMBL
	Growth_fac_rcpt_cys_sf	UniProtKB/TrEMBL
	LDL_receptor-like_sf	UniProtKB/TrEMBL
	LDLR_class-A_CS	UniProtKB/TrEMBL
	LDLR_classB_rpt	UniProtKB/TrEMBL
	LDrepeatLR_classA_rpt	UniProtKB/TrEMBL
KEGG Report	cfa:476336	UniProtKB/TrEMBL
NCBI Gene	VLDLR	ENTREZGENE
PANTHER	LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED	UniProtKB/TrEMBL
	VERY LOW-DENSITY LIPOPROTEIN RECEPTOR	UniProtKB/TrEMBL
Pfam	EGF_CA	UniProtKB/TrEMBL
	FXa_inhibition	UniProtKB/TrEMBL
	Ldl_recept_a	UniProtKB/TrEMBL
	Ldl_recept_b	UniProtKB/TrEMBL
PRINTS	LDLRECEPTOR	UniProtKB/TrEMBL
PROSITE	ASX_HYDROXYL	UniProtKB/TrEMBL
	EGF_2	UniProtKB/TrEMBL
	EGF_3	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
	LDLRA_1	UniProtKB/TrEMBL
	LDLRA_2	UniProtKB/TrEMBL
	LDLRB	UniProtKB/TrEMBL
SMART	EGF	UniProtKB/TrEMBL
	EGF_CA	UniProtKB/TrEMBL
	LDLa	UniProtKB/TrEMBL
	SM00135	UniProtKB/TrEMBL
Superfamily-SCOP	EGF/Laminin	UniProtKB/TrEMBL
	SSF57184	UniProtKB/TrEMBL
	SSF57424	UniProtKB/TrEMBL
	YWTD domain	UniProtKB/TrEMBL
UniProt	A0A8C0LSZ2	ENTREZGENE
	A0A8C0LX46	ENTREZGENE
	A0A8C0N420	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0N5Z3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0N8P3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0QCS9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0RWQ3_CANLF	UniProtKB/TrEMBL
	A0A8C0RX41_CANLF	UniProtKB/TrEMBL
	A0A8I3MF94	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MFA4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MSV0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3RQN7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NMA8_CANLF	UniProtKB/TrEMBL
	A0A8P0NMC0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NUR6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0TP72	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0TU47	ENTREZGENE, UniProtKB/TrEMBL
	Q6H100_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:48269	ENTREZGENE

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InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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