Gene:	Glud1 ( Rattus norvegicus ) glutamate dehydrogenase 1
Description:	catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate and may be a candidate memory-related gene
Synonyms:	Glutamate dehydrogenase; RNGLUDEHA; MGC93608; memory related gene 2; Glud; MRG-2;  (details...)
ArrayIDs:	rc_AI137421_at; 6694638; rc_AI179613_at; A_44_P259908; 5726883; 6728953; 1387878_at; 5755280; 5827106; rc_AI233216_at; 5922969; GE1165677; 1370200_at; 5786471; A_42_P660048; 5814634; 6227581; 5930271; 5655329; A_44_P472500; 5893682; GE19830; 6237960; 6470792; A_44_P155460; A_43_P14157; 6461599; 6309297; 5858843; 6068520; A_44_P486853;  (details...)
Gene Type:	protein-coding
Additional Data
Markers:	D16Mgh3
Homologs
Homo sapiens: GLUD1     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Glud1     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Glud1 genome assembly 3.1 16 9965715 - 9999248     Rat Celera Assembly 16 5542860 - 5576344     RGSC genome assembly v3.4 16 9965718 - 9999254     Cytogenetic 16 p16 Mus musculus Glud1 Mouse genome assembly build 36.1 14 35123937 - 35158093     Cytogenetic 14 14 B Homo sapiens GLUD1 human genome assembly 10 88800224 - 88844603     Human genome assembly build 36.2 10 88800223 - 88844603     Cytogenetic 10 q23.3   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Other Map Data:	Associated SSLP Map Locations STS D16Mgh3 genome assembly 3.1 16 9964207 - 9964431     RGSC genome assembly v3.4 16 9964209 - 9964433
Annotation
Molecular Function	Gene Ontology GTP binding,  nucleotide binding,  leucine binding ...  (details...)
Biological Process	Gene Ontology positive regulation of insulin secretion,  long-term memory,  oxidation reduction ...  (details...)
Cellular Component	Gene Ontology mitochondrion,  mitochondrial matrix,  cytoplasm ...  (details...)
Disease	Ontology Hypoglycemia,  Hyperammonemia,  Hyperinsulinism (details...)
Phenotype	Ontology increased circulating ammonia level,  increased circulating insulin level (details...)
Pathway	Ontology arginine and proline metabolic pathway,  D-glutamine and D-glutamate metabolic pathway,  glutamate metabolic pathway ...  (details...)
Transcript structure	Note Reference contains 13 exons and spans approximately 34 kb pairs 632876 promoter contains binding sites of the transcription factors Sp1 and Zif268 632876
External Links
Databases	DATABASE ID SOURCE SMART: ELFV_dehydrog IPI PROSITE: GLFV_DEHYOGENASE IPI UNIPARC: UPI0000163C29 IPI KEGG Report: rno:24399 ENTREZGENE HomoloGene Group ID: 55885 ENTREZGENE Germonline: 2708 Pfam: ELFV_dehydrog IPI Pfam: ELFV_dehydrog_N IPI KEGG Pathway: 00471 ENTREZGENE KEGG Pathway: 00251 ENTREZGENE KEGG Pathway: 00330 ENTREZGENE KEGG Pathway: 00910 ENTREZGENE InterPro: Glu/Leu/Phe/Val_DH_C. IPI InterPro: Glu/Leu/Phe/Val_DH. IPI InterPro: Glu/Leu/Phe/Val_DH_dimer. IPI InterPro: NAD(P)-bd_dom. IPI Ensembl Protein: ENSRNOP00000013789 IPI IPI: IPI00324633 IPI Gene3D-CATH: NAD(P)-bd IPI Entrez Gene: Glud1 ENTREZGENE IMAGE_CLONE: IMAGE:7107138 IMAGE-MGC_LOAD MGC_CLONE: MGC:93608 IMAGE-MGC_LOAD Ensembl Genes: ENSRNOG00000010222 IPI TIGR: TC216839 UniProt: DHE3_RAT IPI Superfamily-SCOP: NAD(P)-bd IPI RatMap: 33981 ENTREZGENE PANTHER: GLFV_DH IPI PRINTS: GLFDHGNASE. IPI
Sequences	Nucleotide: NM_012570 Get FASTA Search GEO Profiles Nucleotide: U95148 Get FASTA Search GEO Profiles Nucleotide: BC081841 Get FASTA Search GEO Profiles Nucleotide: X14044 Get FASTA Search GEO Profiles Nucleotide: X64365 Get FASTA Search GEO Profiles Nucleotide: X14223 Get FASTA Search GEO Profiles Nucleotide: CH474046 Get FASTA Search GEO Profiles (View all 7 Nucleotide Accessions) Protein: NP_036702 Get FASTA Protein: EDL88881 Get FASTA Protein: EDL88882 Get FASTA Protein: CAA45717 Get FASTA Protein: AAH81841 Get FASTA Protein: AAB70012 Get FASTA Protein: CAA32202 Get FASTA Protein: CAA32441 Get FASTA Protein: P10860 Get FASTA (View all 9 Protein Accessions)
Clusters	UniGene: 55106
References
Curated References	16 references in RGD related to Glud1
Other References	11 other references at PubMed related to Glud1
Database Information
RGD ID	2708
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 06-NOV-02: Glud1 glutamate dehydrogenase 1 Glutamate dehydrogenase APPROVED Name updated 625702 10-JUN-02: Glud1 Glutamate dehydrogenase APPROVED Symbol and Name status set to approved 70586