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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2708
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Glud1
Name: glutamate dehydrogenase 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Glud1affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of GLUD1 mRNAPMID:22298810 PMID:34747641
Glud1decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of GLUD1 mRNAPMID:16054898 PMID:16960034 PMID:18465118 PMID:18796159 PMID:21215274 PMID:21724226 PMID:22342509 PMID:27136898
Glud1decreases expressionISOGlud1 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of GLUD1 mRNA; Tetrachlorodibenzodioxin results in decreased expression of GLUD1 proteinPMID:16960034 PMID:18796159 PMID:38013089
Glud1decreases expressionISOGLUD1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of GLUD1 mRNAPMID:20106945
Glud1multiple interactionsISOGlud1 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GLUD1 mRNAPMID:17942748
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