Gene: Acat1 (acetyl-CoA acetyltransferase 1) Rattus norvegicus
Symbol: Acat1
Name: acetyl-CoA acetyltransferase 1
Description: ENCODES a protein that exhibits acetyl-CoA C-acetyltransferase activity; coenzyme binding; enzyme binding; INVOLVED IN adipose tissue development; brain development; liver development; PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria disease pathway; 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyacyl-CoA dehydrogenase deficiency pathway; ASSOCIATED WITH Kidney Failure, Chronic; Nephrotic Syndrome; Arteriosclerosis (ortholog); FOUND IN mitochondrial matrix; mitochondrion; mitochondrial inner membrane (ortholog); INTERACTS WITH (+)-alpha-tocopherol; 1,2,4-trimethylbenzene; 1,3-dinitrobenzene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acetoacetyl-CoA thiolase; Acetyl-Co A acetyltransferase 1 mitochondrial; Acetyl-Co A acetyltransferase 1, mitochondrial; acetyl-CoA acetyltransferase, mitochondrial; acetyl-Coenzyme A acetyltransferase 1; RATACAL
Homo sapiens (human) : ACAT1 (acetyl-CoA acetyltransferase 1)  HGNC  AGR
Mus musculus (house mouse) : Acat1 (acetyl-Coenzyme A acetyltransferase 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Acat1 (acetyl-CoA acetyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ACAT1 (acetyl-CoA acetyltransferase 1)
Canis lupus familiaris (dog) : ACAT1 (acetyl-CoA acetyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acat1 (acetyl-CoA acetyltransferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0858,166,990 - 58,195,884 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0856,749,861 - 56,778,336 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4857,044,478 - 57,072,970 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1857,063,521 - 57,092,024 (-)NCBI
Celera853,470,530 - 53,499,505 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Acat1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2016
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE