Cat (catalase) - Rat Genome Database

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Gene: Cat (catalase) Rattus norvegicus
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Symbol: Cat
Name: catalase
RGD ID: 2279
Description: Enables catalase activity. Involved in several processes, including response to L-ascorbic acid; response to ozone; and response to vitamin A. Located in extracellular space and peroxisomal matrix. Used to study brain ischemia; cholestasis; colitis; and lung disease (multiple). Biomarker of several diseases, including alcohol use disorder; artery disease (multiple); auditory system disease (multiple); eye disease (multiple); and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including acatalasia; eye disease (multiple); lung disease (multiple); osteonecrosis; and pseudoxanthoma elasticum. Orthologous to human CAT (catalase); PARTICIPATES IN disulfiram pharmacodynamics pathway; tryptophan metabolic pathway; amyotrophic lateral sclerosis pathway; INTERACTS WITH (+)-artemisinin; (+)-catechin; (+)-pilocarpine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cas1; Cat01; Catl; Cs-1; CS1; RATCAT01; RATCATL
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Is Marker For: QTLs:   Tsu1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83110,297,340 - 110,329,526 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3110,297,342 - 110,329,526 (-)EnsemblGRCr8
mRatBN7.2389,842,393 - 89,874,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl389,842,399 - 89,874,478 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx393,335,845 - 93,368,082 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03101,934,911 - 101,967,152 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0399,765,855 - 99,798,079 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0393,379,872 - 93,412,058 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl393,379,874 - 93,412,058 (-)Ensemblrn6Rnor6.0
Rnor_5.03100,021,857 - 100,054,043 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4388,654,077 - 88,686,212 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera388,911,241 - 88,943,392 (-)NCBICelera
RGSC_v3.1388,550,504 - 88,582,640 (+)NCBI
RH 3.4 Map3718.62RGD
Cytogenetic Map3q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
Abnormalities, Drug-Induced  (ISO)
acatalasia  (ISO)
acne  (ISO)
Acute Lung Injury  (ISO)
alcohol use disorder  (IEP)
alcohol-associated liver disease  (IEP)
alcoholic liver cirrhosis  (ISO)
allergic rhinitis  (ISO)
amphetamine abuse  (IEP)
angle-closure glaucoma  (ISO)
aortic disease  (ISO)
asphyxia neonatorum  (ISO)
asthma  (ISO)
autistic disorder  (ISO)
background diabetic retinopathy  (ISO)
bacterial pneumonia  (IDA)
Behcet's disease  (ISO)
Brain Hypoxia-Ischemia  (ISO)
brain ischemia  (IDA,ISO)
breast adenocarcinoma  (ISO)
Breast Neoplasms  (ISO)
bronchopulmonary dysplasia  (IDA)
calcium oxalate nephrolithiasis  (ISO)
cardiomyopathy  (ISO)
Cardiotoxicity  (ISO)
cataract  (IEP,ISO)
Chemical and Drug Induced Liver Injury  (IEP,ISO)
cholestasis  (IDA,ISO)
Chromosome Breakage  (ISO)
Chronic Hepatitis  (ISO)
chronic obstructive pulmonary disease  (ISO)
chronic venous insufficiency  (ISO)
colitis  (IDA)
colorectal carcinoma  (IEP)
congestive heart failure  (ISO)
COVID-19  (ISO)
cutaneous leishmaniasis  (ISO)
cystitis  (IEP)
depressive disorder  (ISO)
diabetes mellitus  (ISO)
Diabetic Nephropathies  (IDA,IEP,IMP,ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (IEP)
diffuse large B-cell lymphoma  (ISO)
dilated cardiomyopathy  (ISO)
disease of cellular proliferation  (ISO)
Disease Progression  (ISO)
Disorders of Environmental Origin  (IEP)
Drug-Induced Dyskinesia  (ISO)
Edema  (ISO)
end stage renal disease  (IEP,ISO)
essential hypertension  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (IEP,ISO)
familial Mediterranean fever  (ISO)
Femur Head Necrosis  (ISO)
fetal alcohol spectrum disorder  (ISO)
fibromyalgia  (ISO)
focal segmental glomerulosclerosis  (ISO)
gastric adenocarcinoma  (ISO)
gastric ulcer  (IEP,ISO)
Genetic Predisposition to Disease  (ISO)
Graves ophthalmopathy  (ISO)
Graves' disease  (ISO)
Hashimoto Disease  (ISO)
Hearing Loss, Cisplatin-Induced  (IEP)
Hearing Loss, Noise-Induced  (ISO)
hepatitis  (ISO)
hepatocellular carcinoma  (ISO)
high grade glioma  (ISO)
Human Influenza  (ISO)
Huntington's disease  (IEP)
Hyperalgesia  (IEP,IMP)
Hyperemia  (ISO)
Hyperhidrosis  (ISO)
hypertension  (IEP,ISO)
hyperthyroidism  (IEP,ISO)
Hypotension  (ISO)
hypothyroidism  (IEP)
Insulin Resistance  (ISO)
keratosis  (ISO)
Kidney Calculi  (ISO)
laryngeal squamous cell carcinoma  (ISO)
Left Ventricular Hypertrophy  (IEP)
lichen planus  (ISO)
lung disease  (IDA,IEP,ISO)
lung non-small cell carcinoma  (ISO)
major depressive disorder  (ISO)
Marfan syndrome  (ISO)
melanoma  (ISO)
Mesothelioma  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
myocardial infarction  (IEP,ISO)
Myocardial Reperfusion Injury  (IEP,ISO)
Nasal Polyps  (ISO)
Necrosis  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
neovascular inflammatory vitreoretinopathy  (ISO)
nephrosis  (ISO)
neurodegenerative disease  (IEP)
newborn respiratory distress syndrome  (ISO)
optic neuritis  (ISO)
otitis media  (IEP)
pancreatic cancer  (ISO)
papillary thyroid carcinoma  (ISO)
pemphigus  (ISO)
Perennial Allergic Rhinitis  (ISO)
phenylketonuria  (IEP)
phobic disorder  (ISO)
pleurisy  (ISO)
pneumoconiosis  (ISO)
Postmenopausal Osteoporosis  (ISO)
pre-malignant neoplasm  (ISO)
Prehypertension  (IEP)
Premature Birth  (ISO)
Presbycusis  (ISO)
proliferative diabetic retinopathy  (ISO)
Protein Deficiency  (ISO)
pseudoxanthoma elasticum  (ISO)
psoriasis  (ISO)
pterygium  (ISO)
pulmonary edema  (ISO)
pulmonary embolism  (ISO)
pulmonary fibrosis  (ISO)
Raynaud disease  (ISO)
renal cell carcinoma  (ISO)
Renoprival Hypertension  (IMP)
Reperfusion Injury  (IDA,IEP,ISO)
Retina Reperfusion Injury  (IEP)
retinal disease  (IEP)
retinitis pigmentosa  (ISO)
rheumatoid arthritis  (ISO)
rhinitis  (ISO)
scabies  (ISO)
sciatic neuropathy  (IEP)
seborrheic dermatitis  (ISO)
senile cataract  (ISO)
sensorineural hearing loss  (IEP)
Sepsis  (IEP)
Skin Neoplasms  (ISO)
status epilepticus  (ISO)
steatotic liver disease  (IEP,ISO)
stomatitis  (IEP)
systemic lupus erythematosus  (ISO)
toxic encephalopathy  (IEP)
Turner syndrome  (ISO)
tympanosclerosis  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
Ureteral Calculi  (ISO)
ureteral obstruction  (IEP)
urinary bladder cancer  (ISO)
Viral Bronchiolitis  (ISO)
vitiligo  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-albicanol  (ISO)
(+)-artemisinin  (EXP)
(+)-beta-thujone  (ISO)
(+)-catechin  (EXP,ISO)
(+)-pilocarpine  (EXP,ISO)
(+)-schisandrin B  (EXP)
(+)-sesamin  (EXP,ISO)
(+)-syringaresinol beta-D-glucoside  (ISO)
(+)-taxifolin  (EXP,ISO)
(+)-trans-(S)-allethrin  (ISO)
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(-)-quinic acid  (ISO)
(-)-selegiline  (EXP,ISO)
(20S)-ginsenoside Rg3  (EXP,ISO)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(2E,4E)-hexa-2,4-dienoic acid  (EXP)
(3,4-dihydroxyphenyl)acetic acid  (ISO)
(E)-cinnamyl alcohol  (ISO)
(E)-thiamethoxam  (EXP,ISO)
(R)-adrenaline  (ISO)
(R)-camphor  (ISO)
(R)-carnitine  (EXP)
(R)-linalyl acetate  (ISO)
(R)-lipoic acid  (EXP,ISO)
(R)-noradrenaline  (EXP)
(R,R)-tramadol  (EXP)
(R,R,R)-alpha-tocopherol  (EXP,ISO)
(RS)-norcoclaurine  (EXP)
(S)-(-)-perillyl alcohol  (EXP,ISO)
(S)-amphetamine  (EXP)
(S)-colchicine  (EXP)
(S)-naringenin  (EXP,ISO)
(S)-nicotine  (EXP,ISO)
(Z)-ligustilide  (ISO)
1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,10-phenanthroline  (ISO)
1,2-dichlorobenzene  (EXP)
1,2-dichloroethane  (EXP,ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1,2-naphthoquinone  (ISO)
1,2-phenylenediamine  (ISO)
1,3-dichloropropan-2-ol  (EXP)
1,4,7-triazonane  (ISO)
1,4-benzoquinone  (ISO)
1,4-dibromobenzene  (EXP)
1,4-dithiothreitol  (ISO)
1,8-cineole  (ISO)
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine  (EXP)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-benzylpiperazine  (ISO)
1-bromopropane  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
11-deoxycorticosterone  (EXP)
13-HPODE  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP,ISO)
1D-myo-inositol 1,4,5-trisphosphate  (ISO)
1H-imidazole  (ISO)
1H-pyrazole  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrabromodibenzodioxine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,5-trichlorophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO)
2,4,6-trinitrotoluene  (ISO)
2,4-D  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,4-dichlorophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,5-dihydroxybenzoic acid  (ISO)
2,5-hexanedione  (EXP)
2,6-di-tert-butyl-4-methylphenol  (EXP)
2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one  (ISO)
2-acetamidofluorene  (EXP)
2-amino-2-deoxy-D-galactopyranose  (EXP,ISO)
2-ethoxyethanol  (EXP)
2-hydroxyethyl methacrylate  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid  (EXP)
2-methyl-6-(phenylethynyl)pyridine  (EXP,ISO)
2-methylcholine  (ISO)
2-nitropropane  (EXP)
2-palmitoylglycerol  (ISO)
2-tert-butylhydroquinone  (EXP,ISO)
26-hydroxycholesterol  (ISO)
3',4',7-trihydroxyisoflavone  (ISO)
3',5'-cyclic GMP  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3,4-dihydroxybenzaldehyde  (ISO)
3,4-dihydroxybenzoic acid  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-(Methylthio)-1-propene  (EXP)
3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonic acid  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-hydroxypyruvic acid  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyl-3H-imidazo[4,5-f]quinolin-2-amine  (ISO)
3-methyladenine  (ISO)
3-methylglutaric acid  (EXP)
3-nitropropanoic acid  (EXP)
3-phenylprop-2-enal  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4'-epidoxorubicin  (EXP,ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(dimethylamino)azobenzene  (ISO)
4-hexylbenzene-1,3-diol  (ISO)
4-hydroxy-TEMPO  (EXP)
4-Hydroxybenzyl isothiocyanate  (EXP)
4-hydroxynon-2-enal  (ISO)
4-methoxycinnamic acid  (EXP)
4-methylumbelliferone  (ISO)
4-nonylphenol  (EXP)
4-phenylbutyric acid  (ISO)
4-vinylcyclohexene dioxide  (ISO)
5-(2-chloroethyl)-4-methylthiazole  (ISO)
5-aminolevulinic acid  (EXP)
5-fluorouracil  (EXP,ISO)
5-formyltetrahydrofolic acid  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP,ISO)
5-methoxypsoralen  (EXP)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (EXP)
7,12-dimethyltetraphene  (EXP,ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
7H-xanthine  (ISO)
8-Br-cAMP  (ISO)
9,10-phenanthroquinone  (ISO)
9,11,13-octadecatrienoic acid  (EXP)
9H-xanthine  (ISO)
[6]-Shogaol  (ISO)
abamectin  (EXP)
acephate  (EXP)
acetaldehyde  (ISO)
acetamide  (EXP)
acetamiprid  (EXP,ISO)
acetic acid  (EXP)
acetone  (EXP,ISO)
acetylsalicylic acid  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
acrylic acid  (EXP)
acrylonitrile  (EXP,ISO)
adenine  (EXP)
ADP  (EXP)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
agomelatine  (EXP)
AICA ribonucleotide  (ISO)
albuterol  (ISO)
alcohol  (ISO)
aldehydo-D-glucose  (EXP,ISO)
aldicarb  (EXP)
alendronic acid  (EXP,ISO)
alginic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (EXP,ISO)
all-trans-retinyl palmitate  (EXP)
allethrin  (EXP)
allopurinol  (EXP)
alloxan  (EXP,ISO)
Allyl chloride  (EXP)
allyl isothiocyanate  (EXP)
alpha,alpha-trehalose  (EXP)
alpha-Artemisic acid  (ISO)
alpha-D-galactose  (EXP,ISO)
alpha-hexachlorocyclohexane  (EXP)
alpha-hexylcinnamaldehyde  (ISO)
alpha-linolenic acid  (EXP)
alpha-naphthoflavone  (ISO)
alpha-pinene  (EXP)
Alpinetin  (ISO)
aluminium atom  (EXP,ISO)
aluminium hydroxide  (EXP,ISO)
aluminium oxide  (EXP)
aluminium phosphide  (EXP)
aluminium trinitrate  (EXP,ISO)
aluminium(0)  (EXP,ISO)
amarogentin  (ISO)
amikacin  (ISO)
aminoacetone  (EXP)
aminoguanidine  (EXP,ISO)
aminophylline  (ISO)
amiodarone  (EXP,ISO)
amitraz  (EXP)
amitriptyline  (ISO)
amitrole  (EXP,ISO)
ammonium acetate  (EXP)
ammonium chloride  (EXP)
Ammothamnine  (EXP)
amosite asbestos  (ISO)
amoxicillin  (EXP)
amphetamine  (ISO)
amphibole asbestos  (ISO)
amphotericin B  (EXP)
andrographolide  (EXP,ISO)
Anemoside B4  (ISO)
anethole  (EXP)
Anetholtrithion  (ISO)
anthocyanin  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
anthracene-1,8,9-triol  (ISO)
antimycin A  (ISO)
apigenin  (EXP,ISO)
apocynin  (EXP)
aprindine  (ISO)
arachidonic acid  (EXP)
arecoline  (EXP)
Aristolactam I  (EXP)
aristolochic acid A  (EXP)
arjunolic acid  (EXP,ISO)
Aroclor 1254  (EXP,ISO)
arotinolol  (EXP)
arsane  (EXP,ISO)
arsenic acid  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenic trichloride  (ISO)
arsenite(3-)  (EXP,ISO)
Arsenobetaine  (ISO)
arsenous acid  (EXP,ISO)
artesunate  (ISO)
asiatic acid  (EXP)
asiaticoside  (EXP)
asoxime chloride  (EXP)
aspartame  (EXP,ISO)
astaxanthin  (EXP,ISO)
astemizole  (EXP)
astilbin  (ISO)
atazanavir sulfate  (ISO)
atenolol  (EXP)
atorvastatin calcium  (EXP,ISO)
ATP  (ISO)
atrazine  (EXP,ISO)
aucubin  (ISO)
aureusidin  (ISO)
bacitracin  (EXP)
Bacoside a  (EXP)
baicalin  (ISO)
Bandrowski's base  (ISO)
barium chloride  (EXP)
barium(0)  (EXP)
beclomethasone  (ISO)
benidipine  (EXP)
benzbromarone  (EXP)
benzene  (EXP,ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzoic acid  (ISO)
benzopyran  (EXP)
benzoquinones  (ISO)
Benzoyl peroxide  (ISO)
benzyl isothiocyanate  (EXP)
berberine  (EXP,ISO)
Bergenin  (EXP,ISO)
beta-carboline  (ISO)
beta-carotene  (EXP,ISO)
beta-hexachlorocyclohexane  (EXP)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
beta-patchoulene  (EXP)
Betanin  (EXP)
betulin  (EXP)
betulinic acid  (EXP)
bezafibrate  (EXP,ISO)
bifenthrin  (EXP,ISO)
biguanides  (EXP)
bilirubin IXalpha  (EXP,ISO)
biochanin A  (ISO)
biphenyl-2-ol  (ISO)
bis(2-butoxyethyl)phthalate  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP)
Bisphenol A glycidylmethacrylate  (ISO)
bisphenol AF  (EXP,ISO)
Bisphenol B  (EXP,ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP,ISO)
Boldine  (EXP,ISO)
boric acid  (EXP,ISO)
boron atom  (EXP)
bortezomib  (EXP)
bosentan  (ISO)
Brodifacoum  (EXP)
brucine  (EXP)
Brusatol  (EXP,ISO)
buprenorphine  (EXP,ISO)
buprofezin  (ISO)
bupropion  (ISO)
buspirone  (EXP)
busulfan  (ISO)
butan-1-ol  (ISO)
butane-2,3-dione  (ISO)
Butralin  (EXP)
butylated hydroxyanisole  (EXP)
Butylbenzyl phthalate  (ISO)
Butylparaben  (EXP)
C60 fullerene  (ISO)
cadmium acetate  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium telluride  (EXP,ISO)
caffeine  (EXP,ISO)
calcidiol  (EXP)
calciol  (EXP)
calcium atom  (EXP,ISO)
calcium oxalate  (EXP)
Calcium propionate  (EXP)
calcium(0)  (EXP,ISO)
calycosin-7-O-beta-D-glucoside  (ISO)
camphor  (ISO)
camptothecin  (EXP)
candesartan  (EXP)
cannabidiol  (ISO)
canrenoic acid  (EXP)
capecitabine  (EXP)
capsaicin  (ISO)
captan  (ISO)
carbendazim  (EXP)
carbimazole  (EXP)
carbofuran  (EXP)
carbon atom  (ISO)
carbon disulfide  (EXP)
carbon monoxide  (EXP,ISO)
carbon nanotube  (EXP,ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
carboplatin  (EXP)
Cardamonin  (EXP)
carfilzomib  (EXP)
carmustine  (EXP)
carnosic acid  (ISO)
carnosine  (ISO)
carotenoid  (ISO)
carrageenan  (EXP,ISO)
carteolol  (ISO)
carvacrol  (EXP,ISO)
carvedilol  (EXP)
casticin  (ISO)
cefaloridine  (EXP)
cefepime  (ISO)
ceftriaxone  (EXP,ISO)
cefuroxime  (EXP)
celastrol  (EXP,ISO)
celecoxib  (ISO)
ceric oxide  (EXP,ISO)
cerium trichloride  (ISO)
chalcones  (EXP)
chenodeoxycholic acid  (ISO)
chitosan  (EXP)
chloramphenicol  (ISO)
chloric acid  (ISO)
chlorite  (ISO)
chloroform  (EXP)
chlorogenic acid  (EXP,ISO)
chlorophyll a  (EXP)
chlorophyllin  (ISO)
chloroquine  (EXP,ISO)
chlorotoluron  (ISO)
chlorpromazine  (EXP,ISO)
chlorpyrifos  (EXP,ISO)
chlorpyrifos-methyl  (EXP)
chlortetracycline  (ISO)
Cholestane-3,5,6-triol  (EXP)
cholesterol  (EXP,ISO)
cholic acid  (EXP)
choline  (EXP,ISO)
chondroitin sulfate  (EXP)
chromium atom  (EXP,ISO)
chromium trioxide  (ISO)
chromium(3+) trichloride  (EXP)
chromium(6+)  (EXP,ISO)
chrysene  (ISO)
chrysin  (EXP,ISO)
ciglitazone  (ISO)
cinnamyl alcohol  (ISO)
ciprofibrate  (EXP)
ciprofloxacin  (EXP)
cis-caffeic acid  (EXP,ISO)
cisplatin  (EXP,ISO)
citalopram  (ISO)
citral  (EXP)
citric acid  (ISO)
clemizole  (EXP)
Clinofibrate  (EXP)
clofibrate  (EXP,ISO)
Clofop  (ISO)
clomipramine  (ISO)
clotrimazole  (ISO)
clozapine  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP,ISO)
coenzyme Q10  (EXP,ISO)
colforsin daropate hydrochloride  (EXP)
colistin  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (EXP,ISO)
cordycepin  (EXP,ISO)
corilagin  (EXP,ISO)
corn oil  (ISO)
corticosterone  (ISO)
costunolide  (EXP)
coumarin  (EXP,ISO)
crocidolite asbestos  (EXP,ISO)
crocin-1  (EXP,ISO)
crotonaldehyde  (EXP)
CU-O LINKAGE  (EXP,ISO)
cucurbitacin B  (ISO)
cumene hydroperoxide  (EXP,ISO)
curcumin  (EXP,ISO)
cyanides  (ISO)
cyanocob(III)alamin  (EXP,ISO)
Cyanoginosin  (EXP)
cyantraniliprole  (EXP)
cycloartenol  (ISO)
cycloheximide  (EXP)
Cyclopamine  (EXP,ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (EXP,ISO)
cyhalothrin  (EXP,ISO)
cylindrospermopsin  (EXP,ISO)
cypermethrin  (EXP,ISO)
cytarabine  (EXP)
cytochalasin B  (ISO)
D-glucose  (EXP,ISO)
D-penicillamine  (ISO)
daidzein  (EXP,ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
dapagliflozin  (EXP)
dapsone  (EXP)
daunorubicin  (ISO)
DDD  (EXP)
DDE  (EXP,ISO)
DDT  (EXP)
decabromodiphenyl ether  (ISO)
Decursin  (ISO)
dehydroepiandrosterone  (EXP)
delphinidin  (ISO)
delta-hexachlorocyclohexane  (EXP)
Dendrobine  (ISO)
deoxycholic acid  (ISO)
Deoxycorticosterone acetate  (EXP)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (EXP,ISO)
desogestrel  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
Di-n-octyl phthalate  (ISO)
diallyl disulfide  (EXP)
Diallyl sulfide  (EXP)
diallyl trisulfide  (EXP)
Diallyltetrasulfane  (EXP)
diarsenic trioxide  (EXP,ISO)
diazepam  (EXP,ISO)
diazinon  (EXP)
diazoxon  (EXP)
dibenziodolium  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichlorine  (ISO)
dichloroacetic acid  (ISO)
dichloromethane  (ISO)
dichlorvos  (EXP,ISO)
dichromium trioxide  (ISO)
diclofenac  (EXP,ISO)
diclofop-methyl  (EXP)
dicoumarol  (EXP,ISO)
dicyclanil  (ISO)
dieckol  (ISO)
diethyl maleate  (EXP)
diethyl phthalate  (EXP,ISO)
diethyldithiocarbamic acid  (ISO)
difenoconazole  (EXP,ISO)
dihydroactinidiolide  (ISO)
dihydroartemisinin  (ISO)
dihydrocapsaicin  (ISO)
dihydrogen  (ISO)
diisobutyl phthalate  (ISO)
Diisodecyl phthalate  (ISO)
diisononyl phthalate  (ISO)
diltiazem  (EXP)
dimethoate  (EXP,ISO)
dimethyl fumarate  (EXP)
dimethyl sulfoxide  (ISO)
dimethylarsinic acid  (EXP,ISO)
dimethylarsinous acid  (EXP,ISO)
Diosbulbin B  (ISO)
diosmin  (EXP)
dioxygen  (EXP,ISO)
dipentyl phthalate  (EXP)
diphenyl diselenide  (EXP,ISO)
diprotium  (ISO)
diprotium oxide  (EXP,ISO)
diquat  (EXP,ISO)
disodium selenite  (EXP)
disulfiram  (ISO)
dithianon  (ISO)
diuron  (EXP)
dizocilpine maleate  (EXP)
Dodecyl gallate  (ISO)
donepezil hydrochloride  (ISO)
dopamine  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
ebselen  (EXP)
edaravone  (ISO)
efavirenz  (EXP)
elemental boron  (EXP)
elemental carbon  (ISO)
elemental selenium  (EXP,ISO)
ellagic acid  (EXP)
emamectin benzoate  (ISO)
embelin  (EXP)
emodin  (EXP,ISO)
empagliflozin  (EXP)
enalapril  (EXP)
endosulfan  (EXP,ISO)
enilconazole  (ISO)
enniatin  (ISO)
enrofloxacin  (EXP)
enzyme inhibitor  (EXP)
eplerenone  (EXP)
erdosteine  (EXP)
Eremanthin  (EXP)
ergothioneine  (EXP)
eriodictyol  (EXP)
erythromycin A  (ISO)
erythromycin estolate  (EXP)
erythrosin B  (EXP)
esculetin  (EXP)
etacrynic acid  (ISO)
etanidazole  (ISO)
ethambutol  (EXP)
ethanol  (EXP,ISO)
Ethyl 4-methoxycinnamate  (EXP)
ethylbenzene  (EXP)
ethylene glycol  (EXP)
ethylenediaminetetraacetic acid  (ISO)
etoposide  (EXP,ISO)
eugenol  (EXP,ISO)
EUK-8  (ISO)
eumelanin  (ISO)
excitatory amino acid agonist  (EXP)
famotidine  (EXP,ISO)
farnesol  (EXP,ISO)
favipiravir  (EXP)
fenitrothion  (EXP)
fenofibrate  (EXP,ISO)
fenoterol  (ISO)
fenpropathrin  (EXP)
fenpyroximate  (EXP,ISO)
fenvalerate  (EXP)
ferric oxide  (ISO)
ferrocene  (EXP)
ferruginol  (EXP)
ferulic acid  (EXP,ISO)
finasteride  (EXP)
fipronil  (EXP,ISO)
fisetin  (EXP)
flavonoids  (EXP,ISO)
flubendiamide  (EXP)
fludioxonil  (ISO)
fluorene  (ISO)
fluoxetine  (EXP)
fluphenazine  (EXP)
flutamide  (EXP)
fluvastatin  (EXP,ISO)
folic acid  (EXP,ISO)
folpet  (ISO)
formaldehyde  (EXP,ISO)
Forsythiaside  (ISO)
fraxetin  (ISO)
fructose  (EXP,ISO)
fucoxanthin  (ISO)
fulvestrant  (EXP)
fumonisin B1  (EXP,ISO)
furan  (EXP,ISO)
furans  (ISO)
gadolinium atom  (ISO)
gadolinium trichloride  (EXP)
galactose  (EXP,ISO)
galangin  (EXP,ISO)
galanthamine  (EXP)
galanthamine Trifluoroacetic acid  (EXP)
Galbanic acid  (ISO)
gallein  (EXP)
gallic acid  (EXP,ISO)
gallium nitrate  (ISO)
gamma-aminobutyric acid  (EXP,ISO)
gamma-hexachlorocyclohexane  (EXP,ISO)
gamma-Oryzanol (TN)  (ISO)
gamma-tocopherol  (ISO)
Ganoderic acid A  (ISO)
Ganoderic acid T  (ISO)
Gastrodin  (EXP,ISO)
gemfibrozil  (EXP,ISO)
Geniposide  (ISO)
genistein  (EXP,ISO)
gentamycin  (EXP)
geranial  (EXP)
geraniol  (EXP,ISO)
gingerol  (EXP,ISO)
Ginkgolide C  (EXP)
ginsenoside Rd  (EXP)
ginsenoside Re  (ISO)
ginsenoside Rg1  (EXP,ISO)
glafenine  (EXP)
gliclazide  (EXP)
glucagon  (ISO)
glucose  (EXP,ISO)
glutathione  (EXP,ISO)
Glutathione ethyl ester  (EXP)
glyburide  (EXP,ISO)
glycerol  (EXP)
glycine betaine  (EXP,ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glycolaldehyde  (EXP)
glycyrrhetinate  (EXP,ISO)
glycyrrhetinic acid  (EXP,ISO)
glyoxal  (EXP)
glyphosate  (EXP,ISO)
gold atom  (ISO)
gold(0)  (ISO)
gossypin  (EXP)
gossypol  (ISO)
haloperidol  (EXP,ISO)
harman  (ISO)
hemin  (EXP,ISO)
heparin  (ISO)
herbacetin  (EXP)
herbicide  (ISO)
hesperetin  (EXP,ISO)
hesperidin  (EXP,ISO)
hexachlorobenzene  (EXP,ISO)
hexadecanoic acid  (EXP,ISO)
hexaflumuron  (EXP)
histamine  (EXP,ISO)
homocysteine  (EXP,ISO)
Honokiol  (EXP)
hyaluronic acid  (ISO)
hydrazine  (EXP)
hydrochlorothiazide  (EXP)
hydrogen chloride  (EXP,ISO)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (EXP,ISO)
hydroquinone O-beta-D-glucopyranoside  (EXP)
hydroxyl  (ISO)
hydroxylamine  (ISO)
hydroxysafflor yellow A  (ISO)
hydroxytyrosol  (EXP,ISO)
hymexazol  (EXP)
hypochlorous acid  (ISO)
iberin  (EXP)
idarubicin  (ISO)
ifosfamide  (EXP)
imetit  (EXP)
imidacloprid  (EXP)
Imipenem-cilastatin  (EXP)
imipramine  (EXP,ISO)
imiprothrin  (EXP)
immunological adjuvant  (EXP)
indirubin-3'-monoxime  (ISO)
indole-3-acetic acid  (EXP,ISO)
indole-3-methanol  (EXP,ISO)
indometacin  (EXP,ISO)
inositol  (EXP)
inulin  (ISO)
iron atom  (EXP,ISO)
iron dextran  (EXP,ISO)
iron trichloride  (ISO)
iron(0)  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (ISO)
iron(III) nitrilotriacetate  (EXP)
isoeugenol  (ISO)
isoflurane  (ISO)
isoliquiritigenin  (EXP,ISO)
isoniazide  (EXP,ISO)
isoprenaline  (EXP,ISO)
isorhamnetin  (EXP)
isotretinoin  (EXP,ISO)
ivermectin  (EXP,ISO)
juglone  (ISO)
kaempferol  (EXP,ISO)
kaempferol 3-O-beta-D-glucoside  (ISO)
kainic acid  (EXP,ISO)
ketamine  (EXP)
ketoconazole  (EXP)
ketorolac tromethamine  (EXP)
Kirenol  (ISO)
kojic acid  (EXP)
L-1,4-dithiothreitol  (ISO)
L-arginine  (EXP,ISO)
L-ascorbic acid  (EXP,ISO)
L-cysteine  (EXP)
L-dehydroascorbic acid  (ISO)
L-gamma-glutamyl-L-cysteine  (EXP)
L-methionine  (EXP,ISO)
L-mimosine  (ISO)
lactose  (EXP)
lamivudine  (EXP)
lansoprazole  (EXP)
lanthanum trichloride  (ISO)
lead diacetate  (EXP,ISO)
lead nitrate  (EXP,ISO)
lead(0)  (EXP,ISO)
lead(II) chloride  (EXP,ISO)
leflunomide  (ISO)
lenvatinib  (EXP)
Leonurine  (EXP)
letrozole  (ISO)
levetiracetam  (EXP,ISO)
levocabastine  (ISO)
levonorgestrel  (ISO)
Liensinine  (ISO)
limonene  (EXP)
limonin  (ISO)
linalool  (EXP,ISO)
linalyl acetate  (ISO)
linoleic acid  (EXP,ISO)
linsidomine  (ISO)
lipoic acid  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
lithium atom  (EXP,ISO)
lithium carbonate  (EXP,ISO)
lithium hydride  (EXP,ISO)
loperamide  (EXP)
lopinavir  (ISO)
losartan  (EXP)
lovastatin  (EXP)
lupeol  (EXP,ISO)
lutein  (ISO)
luteolin  (EXP,ISO)
luteolin 7-O-beta-D-glucoside  (ISO)
luzindole  (ISO)
LY294002  (EXP,ISO)
lycopene  (EXP,ISO)
m-xylene  (EXP)
maculosin  (ISO)
magnesium oxide  (EXP)
magnesium sulfate  (EXP)
Magnolol  (EXP)
malachite green cation  (EXP)
malaoxon  (ISO)
malathion  (EXP,ISO)
malonaldehyde  (EXP)
malvidin  (ISO)
mancozeb  (EXP,ISO)
maneb  (EXP,ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP,ISO)
mangiferin  (EXP,ISO)
medroxyprogesterone  (ISO)
medroxyprogesterone acetate  (ISO)
melatonin  (EXP,ISO)
meloxicam  (EXP,ISO)
melphalan  (ISO)
menadione  (EXP,ISO)
mephedrone  (EXP,ISO)
mercaptoethanol  (ISO)
mercury atom  (EXP)
mercury dichloride  (EXP,ISO)
mercury(0)  (EXP)
metam  (ISO)
Metanephrine  (ISO)
metformin  (EXP,ISO)
methamidophos  (EXP)
methamphetamine  (EXP,ISO)
methanol  (ISO)
methapyrilene  (EXP)
methimazole  (EXP,ISO)
methomyl  (EXP)
methotrexate  (EXP,ISO)
methoxychlor  (EXP,ISO)
Methylacrylonitrile  (EXP)
methylarsonic acid  (EXP)
methylglyoxal  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP,ISO)
methylparaben  (ISO)
methylphenidate  (EXP,ISO)
Mezerein  (ISO)
miconazole  (EXP)
microcystin-LR  (EXP,ISO)
mifepristone  (EXP,ISO)
miquelianin  (EXP)
mirabegron  (EXP)
mirtazapine  (EXP)
misonidazole  (ISO)
misoprostol  (EXP)
mitogen  (EXP)
mitoxantrone  (EXP)
molybdenum trioxide  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monocrotaline  (EXP)
monocrotophos  (EXP)
monoethyl phthalate  (ISO)
monooxygen  (ISO)
monosodium L-glutamate  (EXP,ISO)
montelukast  (EXP)
morin  (EXP)
morphine  (ISO)
Morroniside  (EXP)
Muraglitazar  (EXP)
myo-inositol hexakisphosphate  (EXP)
myricetin  (EXP,ISO)
myricitrin  (ISO)
myristicin  (ISO)
myrsinoic acid B  (EXP)
myrtenol  (EXP)
N'-(2,4-dimethylphenyl)-N-methylformamidine  (EXP)
N(gamma)-nitro-L-arginine methyl ester  (EXP)
N,N'-diphenyl-1,4-phenylenediamine  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N,N-Diethylbenzamide  (EXP)
N,N-dimethylacetamide  (ISO)
N,N-dimethylformamide  (ISO)
N,N-dimethylglycine  (ISO)
N-acetyl-beta-D-glucosamine  (ISO)
N-acetyl-D-glucosamine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-acetyl-L-tryptophan  (ISO)
N-acetylserotonin  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-methyl-N-nitrosourea  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
NADP zwitterion  (EXP)
NADP(+)  (EXP)
nafenopin  (EXP)
naloxone  (EXP)
naphthalene-1,2-diol  (ISO)
naproxen  (EXP)
naringin  (EXP,ISO)
nebivolol  (EXP)
nefazodone  (ISO)
Neferine  (EXP)
neoastilbin  (ISO)
neocuproine  (EXP)
neohesperidin  (ISO)
neohesperidin dihydrochalcone  (ISO)
nerolidol  (EXP)
nevadensin  (ISO)
nickel atom  (EXP,ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (EXP,ISO)
nicorandil  (EXP)
nicotinamide  (EXP,ISO)
nicotine  (EXP,ISO)
nicotinic acid  (EXP)
nimesulide  (EXP,ISO)
nimodipine  (EXP)
nitric oxide  (EXP)
nitrofen  (EXP)
nitrofurantoin  (EXP,ISO)
nitrogen dioxide  (EXP,ISO)
nitroglycerin  (EXP)
nitroprusside  (EXP,ISO)
nitroxoline  (ISO)
NMN zwitterion  (ISO)
nobiletin  (EXP,ISO)
Nonylphenol  (EXP)
norwogonin  (EXP)
notoginsenoside R1  (EXP)
NS-398  (ISO)
O-acetyl-L-carnitine  (EXP)
O-methyleugenol  (ISO)
ochratoxin A  (EXP,ISO)
octadecanoic acid  (EXP)
octyl gallate  (ISO)
okadaic acid  (ISO)
olanzapine  (EXP)
oleanolic acid  (EXP,ISO)
oleic acid  (EXP,ISO)
oleuropein  (EXP,ISO)
oligopeptide  (ISO)
Olmesartan medoxomil  (EXP)
omeprazole  (EXP,ISO)
omethoate  (EXP)
Ondansetron  (ISO)
oridonin  (EXP)
orlistat  (EXP,ISO)
osimertinib  (ISO)
ouabain  (EXP)
oxalic acid  (ISO)
oxaliplatin  (EXP,ISO)
oxidopamine  (EXP,ISO)
Oxyfluorfen  (ISO)
oxytetracycline  (ISO)
ozone  (EXP,ISO)
p-toluidine  (EXP)
Pachymic acid  (EXP)
paclitaxel  (EXP,ISO)
Paeonol  (ISO)
Palbinone  (EXP)
palmatine  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parathion-methyl  (EXP)
paroxetine  (ISO)
parthenolide  (EXP)
patchouli alcohol  (EXP)
patulin  (ISO)
pendimethalin  (EXP)
pentachlorophenol  (EXP)
pentetrazol  (EXP,ISO)
Pentoxifylline  (EXP,ISO)
peptidoglycan  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
perillyl alcohol  (EXP,ISO)
perindopril  (EXP)
permethrin  (EXP,ISO)
peroxides  (ISO)
peroxynitrous acid  (ISO)
PHA-665752  (ISO)
phenanthrene  (ISO)
phenethyl caffeate  (EXP,ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (EXP,ISO)
phenylephrine  (EXP)
phenylpropanolamine  (EXP)
phenytoin  (ISO)
PhIP  (EXP,ISO)
phloretin  (EXP,ISO)
phlorizin  (ISO)
phorate  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosphamidon  (ISO)
phytol  (ISO)
piclamilast  (EXP)
pinitol  (EXP,ISO)
pinostrobin  (EXP)
pioglitazone  (EXP,ISO)
piperazine  (ISO)
piperine  (EXP,ISO)
pipoxolan  (ISO)
Piracetam  (ISO)
pirfenidone  (EXP,ISO)
pirinixic acid  (EXP,ISO)
platycodin D  (ISO)
plumbagin  (EXP)
pluronic P-123  (EXP)
Poloxamer  (EXP)
poly(ethylene)  (ISO)
poly(I:C)  (EXP)
poly(vinyl chloride)  (ISO)
ponatinib  (ISO)
porphyrins  (ISO)
potassium bromate  (EXP,ISO)
potassium chloride  (EXP)
potassium chromate  (ISO)
potassium dichromate  (EXP,ISO)
pralidoxime  (ISO)
pravastatin  (ISO)
prednisolone  (EXP)
proanthocyanidin  (EXP,ISO)
probenecid  (ISO)
procyanidin  (ISO)
procyanidin B1  (ISO)
procyanidin B2  (EXP,ISO)
procyanidin B3  (ISO)
prodigiosin  (EXP)
profenofos  (EXP)
propacetamol  (ISO)
propetamphos  (EXP,ISO)
propiconazole  (EXP,ISO)
propionic acid  (EXP)
Propiverine  (EXP)
propofol  (EXP,ISO)
propoxur  (EXP)
prostaglandin E2  (EXP,ISO)
prostaglandin F2alpha  (EXP)
psoralen  (EXP,ISO)
pterostilbene  (ISO)
puerarin  (EXP,ISO)
punicalagin  (EXP)
pyrazine-2-carboxylic acid  (EXP)
pyrazinecarboxamide  (EXP)
pyrethrins  (EXP)
Pyridostigmine bromide  (EXP,ISO)
pyrimethamine  (ISO)
pyrogallol  (EXP,ISO)
pyrroloquinoline quinone  (EXP)
pyrvinium  (EXP)
quartz  (ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (EXP)
quercetin 3-O-beta-D-glucofuranoside  (EXP)
quercetin 3-O-beta-D-glucopyranoside  (EXP)
quercetin 4'-O-beta-D-glucopyranoside  (ISO)
quetiapine fumarate  (EXP)
quinalphos  (EXP,ISO)
quinidine  (ISO)
quinolinic acid  (EXP)
quinolone  (ISO)
quinoxyfen  (ISO)
quizalofop-ethyl  (EXP)
rac-lactic acid  (ISO)
raloxifene  (ISO)
ramipril  (EXP)
ranitidine  (EXP)
reactive oxygen species  (EXP,ISO)
rebaudioside A  (ISO)
Repaglinide  (EXP)
reserpine  (EXP,ISO)
resveratrol  (EXP,ISO)
riboflavin  (EXP)
rifampicin  (EXP)
rivastigmine  (EXP)
robinin  (EXP)
rofecoxib  (EXP)
roflumilast  (EXP)
ropinirole  (EXP)
rosmarinic acid  (ISO)
rosuvastatin calcium  (EXP)
rotenone  (EXP,ISO)
royal jelly  (EXP,ISO)
ruthenium atom  (EXP)
rutin  (EXP,ISO)
ruxolitinib  (ISO)
ryanodine  (EXP)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
S-allylcysteine  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
sabinene  (ISO)
Salidroside  (EXP,ISO)
Salvianolic acid A  (EXP,ISO)
salvianolic acid B  (ISO)
sanguinarine  (ISO)
SB 203580  (ISO)
scopolamine  (EXP,ISO)
selenium atom  (EXP,ISO)
selenocystine  (ISO)
selenomethionine  (ISO)
serotonin  (ISO)
sertraline  (EXP)
Sesamol  (EXP)
sevoflurane  (EXP)
sildenafil citrate  (EXP,ISO)
silibinin  (EXP)
silicic acid  (ISO)
silicon atom  (EXP,ISO)
silicon dioxide  (EXP,ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
silver(1+) nitrate  (ISO)
simvastatin  (EXP,ISO)
sinapic acid  (EXP)
sirolimus  (ISO)
sodium acetate trihydrate  (EXP,ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium benzoate  (EXP)
sodium chlorate  (EXP)
sodium chloride  (ISO)
sodium dichromate  (EXP,ISO)
sodium fluoride  (EXP,ISO)
sodium hydrogencarbonate  (ISO)
sodium nitrate  (EXP)
sodium nitrite  (ISO)
solanesol  (ISO)
soybean oil  (EXP)
spathulenol  (ISO)
squalene  (EXP)
starch  (ISO)
sterigmatocystin  (EXP)
steviol  (ISO)
stevioside  (ISO)
streptozocin  (EXP,ISO)
styrene  (ISO)
succimer  (EXP)
sucrose  (EXP,ISO)
Sudan III  (EXP)
sulfasalazine  (EXP,ISO)
sulfonyldimethane  (EXP)
sulforaphane  (EXP,ISO)
sulfoxaflor  (EXP)
sulfur dioxide  (EXP)
sulpiride  (ISO)
sunitinib  (EXP,ISO)
Sunset Yellow FCF  (EXP,ISO)
superoxide  (ISO)
surfactin  (ISO)
surfactin C  (ISO)
syringic acid  (EXP,ISO)
T-2 toxin  (EXP,ISO)
tacrine  (ISO)
tacrolimus hydrate  (EXP,ISO)
tadalafil  (EXP)
tamoxifen  (EXP,ISO)
tangeretin  (EXP)
tannic acid  (EXP)
taraxerone  (ISO)
tartrazine  (EXP,ISO)
taurine  (EXP,ISO)
tebuconazole  (EXP)
tebufenpyrad  (ISO)
tectorigenin  (ISO)
telmisartan  (EXP)
tembotrione  (EXP)
tenofovir disoproxil fumarate  (EXP)
tert-butyl hydroperoxide  (EXP,ISO)
Tesaglitazar  (EXP)
testosterone  (EXP,ISO)
testosterone cypionate  (ISO)
Testosterone propionate  (EXP)
tetrachloro-1,4-benzoquinone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP,ISO)
tetracyclines  (ISO)
tetrahydrocurcumin  (EXP,ISO)
tetramethylpyrazine  (ISO)
thalidomide  (ISO)
thallium atom  (EXP)
thapsigargin  (EXP)
theaflavin  (EXP)
Theaflavin 3,3'-digallate  (EXP,ISO)
theophylline  (EXP)
thiacloprid  (EXP)
thiamethoxam  (EXP,ISO)
thiazoles  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
thymol  (EXP,ISO)
thymol sulfate(1-)  (EXP,ISO)
thymoquinone  (EXP,ISO)
thyroxine  (EXP)
tiadenol  (EXP)
tianeptine  (EXP)
tirapazamine  (EXP)
Tiron  (ISO)
titanium atom  (ISO)
titanium dioxide  (EXP,ISO)
toluene  (ISO)
Tomentosin  (ISO)
topotecan  (ISO)
Torularhodin  (ISO)
torulene  (ISO)
toxaphene  (ISO)
tramadol  (EXP)
trandolapril  (EXP)
trans-anethole  (EXP)
trans-caffeic acid  (EXP,ISO)
trans-cinnamic acid  (EXP,ISO)
trans-isoeugenol  (ISO)
trans-piceid  (EXP,ISO)
trans-rhaponticin  (EXP)
trazodone  (ISO)
triadimefon  (EXP)
tributyl phosphate  (EXP)
tributylstannane  (EXP,ISO)
trichlorfon  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triclosan  (EXP,ISO)
triflumuron  (ISO)
trilobatin  (ISO)
triolein  (EXP)
triphenyl phosphate  (EXP,ISO)
Triptolide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tris(2-chloroethyl) phosphate  (EXP,ISO)
tris(picolinato)chromium  (EXP)
troglitazone  (EXP,ISO)
tropisetron  (EXP)
tuberostemonine  (ISO)
Tungsten carbide  (ISO)
tyramine  (EXP)
ubiquinones  (EXP)
Ulipristal  (EXP)
umbelliferone  (ISO)
urethane  (ISO)
ursolic acid  (ISO)
usnic acid  (EXP)
valproic acid  (EXP,ISO)
valsartan  (ISO)
vanadium atom  (EXP)
vanadium(0)  (EXP)
vanadyl sulfate  (ISO)
vancomycin  (EXP,ISO)
vanillin  (EXP,ISO)
venlafaxine hydrochloride  (EXP)
vincaleukoblastine  (ISO)
vincristine  (EXP,ISO)
Vinpocetine  (EXP)
vitamin E  (EXP,ISO)
vitamin K  (EXP)
warfarin  (EXP)
water  (EXP,ISO)
wedelolactone  (ISO)
withaferin A  (EXP,ISO)
wogonin  (EXP,ISO)
WR-1065  (ISO)
yohimbine  (EXP)
zafirlukast  (EXP)
zanamivir  (ISO)
zearalenone  (EXP,ISO)
zidovudine  (EXP,ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (EXP,ISO)
zinc molecular entity  (EXP)
zinc oxide  (EXP,ISO)
zinc protoporphyrin  (EXP,ISO)
zinc sulfate  (EXP,ISO)
zinc(0)  (EXP,ISO)
zingerone  (EXP)
zingiberene  (EXP)
ziprasidone  (EXP)
ziram  (ISO)
zolpidem  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aerobic respiration  (ISO)
cellular detoxification of hydrogen peroxide  (IEA,ISO)
cellular oxidant detoxification  (IEA)
cellular response to growth factor stimulus  (IEP)
cholesterol metabolic process  (ISO)
conditioned place preference  (IEP)
hemoglobin metabolic process  (ISO)
hydrogen peroxide catabolic process  (IBA,IDA,IEA,IMP,ISO)
kidney development  (IMP)
negative regulation of apoptotic process  (IEA,IMP,ISO)
obsolete negative regulation of NF-kappaB transcription factor activity  (ISO)
obsolete positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of cell division  (IEA)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
response to activity  (IEP)
response to amitrole  (IEP)
response to auditory stimulus  (ISO)
response to cadmium ion  (IEP)
response to estradiol  (IEP)
response to ethanol  (IEP)
response to fatty acid  (IEP)
response to hydrogen peroxide  (IBA)
response to hyperoxia  (IEP)
response to hypoxia  (IMP)
response to inactivity  (IEP)
response to insulin  (IEP)
response to L-ascorbic acid  (IEP)
response to lead ion  (IEP)
response to light intensity  (IEP)
response to oxidative stress  (IDA,IEA,ISO)
response to ozone  (IEP)
response to phenylpropanoid  (IEP)
response to reactive oxygen species  (IEA,IMP,ISO)
response to toxic substance  (IEP)
response to UV  (IEP)
response to vitamin A  (IEP)
response to vitamin E  (IEP)
response to xenobiotic stimulus  (IEP)
triglyceride metabolic process  (ISO)
ureteric bud development  (IMP)
UV protection  (IEA,ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
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76. Red blood cells induce hypoxic lung inflammation. Kiefmann R, etal., Blood. 2008 May 15;111(10):5205-14. Epub 2008 Feb 12.
77. Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
78. Hyperbaric oxygenation pretreatment induces catalase and reduces infarct size in ischemic rat myocardium. Kim CH, etal., Pflugers Arch. 2001 Jul;442(4):519-25.
79. Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure. Kim HJ and Vaziri ND, Am J Physiol Renal Physiol. 2010 Mar;298(3):F662-71. Epub 2009 Dec 9.
80. Genetic association study of polymorphisms in the catalase gene with the risk of osteonecrosis of the femoral head in the Korean population. Kim TH, etal., Osteoarthritis Cartilage. 2008 Sep;16(9):1060-6. doi: 10.1016/j.joca.2008.02.004. Epub 2008 Mar 18.
81. Chronic effects of ethanol under partial inhibition of catalase activity in the rat heart: light and electron microscopic observations. Kino M, J Mol Cell Cardiol. 1981 Jan;13(1):5-21. doi: 10.1016/0022-2828(81)90225-x.
82. Alterations of serum selenium, zinc, copper, and iron concentrations and some related antioxidant enzyme activities in patients with cutaneous leishmaniasis. Kocyigit A, etal., Biol Trace Elem Res. 1998 Dec;65(3):271-81.
83. Association between variations in CAT and noise-induced hearing loss in two independent noise-exposed populations. Konings A, etal., Hum Mol Genet. 2007 Aug 1;16(15):1872-83. Epub 2007 Jun 13.
84. Response of anti-oxidant enzymes mRNA in the neonatal rat liver exposed to 1,2,3,4-tetrachlorodibenzo-p-dioxin via lactation. Kono Y, etal., Pediatr Int. 2002 Oct;44(5):481-7.
85. Protective effect of rivastigmine against 3-nitropropionic acid-induced Huntington's disease like symptoms: possible behavioural, biochemical and cellular alterations. Kumar P and Kumar A, Eur J Pharmacol. 2009 Aug 1;615(1-3):91-101. Epub 2009 May 13.
86. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
87. A comparative study of the oxidative profile in Graves' disease, Hashimoto's thyroiditis, and papillary thyroid cancer. Lassoued S, etal., Biol Trace Elem Res. 2010 Dec;138(1-3):107-15. doi: 10.1007/s12011-010-8625-1. Epub 2010 Mar 5.
88. Effect of diallyl disulfide on acute gastric mucosal damage induced by alcohol in rats. Lee IC, etal., Hum Exp Toxicol. 2015 Mar;34(3):227-39. doi: 10.1177/0960327114537095. Epub 2014 Jun 27.
89. Protective effects and mechanism of tetramethylpyrazine against lens opacification induced by sodium selenite in rats. Li N, etal., Exp Eye Res. 2011 Jul;93(1):98-102. doi: 10.1016/j.exer.2011.05.001. Epub 2011 May 27.
90. Antioxidant status and immune activity of glycyrrhizin in allergic rhinitis mice. Li XL, etal., Int J Mol Sci. 2011 Jan 26;12(2):905-16. doi: 10.3390/ijms12020905.
91. Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum. Liu KM, etal., Am J Physiol Renal Physiol. 2015 Aug 15;309(4):F318-31. doi: 10.1152/ajprenal.00607.2014. Epub 2015 Jun 24.
92. Promoter variant in the catalase gene is associated with vitiligo in Chinese people. Liu L, etal., J Invest Dermatol. 2010 Nov;130(11):2647-53. doi: 10.1038/jid.2010.192. Epub 2010 Jul 8.
93. Effects of bis (2-butoxyethyl) phthalate on adrenocortical function in male rats in puberty partially via down-regulating NR5A1/NR4A1/NR4A2 pathways. Liu M, etal., Environ Toxicol. 2022 Oct;37(10):2419-2433. doi: 10.1002/tox.23607. Epub 2022 Jun 28.
94. Novel insights into renal D-amino acid oxidase accumulation: propiverine changes DAAO localization and peroxisomal size in vivo. Luks L, etal., Arch Toxicol. 2017 Jan;91(1):427-437. doi: 10.1007/s00204-016-1685-z. Epub 2016 Mar 9.
95. Pain-relieving effects of pulsed magnetic fields in a rat model of carrageenan-induced hindpaw inflammation. Mert T, etal., Int J Radiat Biol. 2014 Jan;90(1):95-103. doi: 10.3109/09553002.2013.835501. Epub 2013 Sep 13.
96. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
97. Ovariectomy increases Na+, K+-ATPase, acetylcholinesterase and catalase in rat hippocampus. Monteiro SC, etal., Mol Cell Endocrinol. 2005 May 31;236(1-2):9-16.
98. Role of catalase and superoxide dismutase activities on oxidative stress in the brain of a phenylketonuria animal model and the effect of lipoic acid. Moraes TB, etal., Cell Mol Neurobiol. 2013 Mar;33(2):253-60. doi: 10.1007/s10571-012-9892-5. Epub 2012 Dec 12.
99. Improvement of renal oxidative stress markers after ozone administration in diabetic nephropathy in rats. Morsy MD, etal., Diabetol Metab Syndr. 2010 May 13;2(1):29. doi: 10.1186/1758-5996-2-29.
100. Hyperoxia-induced lung injury is dose dependent in Wistar rats. Nagato A, etal., Exp Lung Res. 2009 Oct;35(8):713-28.
101. A variant in myeloperoxidase promoter hastens the emergence of hepatocellular carcinoma in patients with HCV-related cirrhosis. Nahon P, etal., J Hepatol. 2012 Feb;56(2):426-32. doi: 10.1016/j.jhep.2011.08.010. Epub 2011 Sep 8.
102. Isolation and characterization of the rat catalase-encoding gene. Nakashima H, etal., Gene 1989 Jul 15;79(2):279-88.
103. Isolation and characterization of the rat catalase-encoding gene. Nakashima H, etal., Gene 1990 May 14;89(2):295.
104. Daily rhythms of catalase and glutathione peroxidase expression and activity are endogenously driven in the hippocampus and are modified by a vitamin A-free diet. Navigatore-Fonzo LS, etal., Nutr Neurosci. 2014 Jan;17(1):21-30. doi: 10.1179/1476830513Y.0000000062. Epub 2013 Nov 26.
105. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
106. Bilirubin is highly effective in preventing in vivo delta-aminolevulinic acid-induced oxidative cell damage. Noriega GO, etal., Biochim Biophys Acta 2003 Jul 14;1638(2):173-8.
107. Comparative effect of topical application of lindane and permethrin on oxidative stress parameters in adult scabies patients. Oberoi S, etal., Clin Biochem. 2007 Nov;40(16-17):1321-4. Epub 2007 Aug 10.
108. The role of catalase in pulmonary fibrosis. Odajima N, etal., Respir Res. 2010 Dec 29;11:183.
109. Oxidative effects of chronic ethanol consumption on the functions of heart and kidney: folic acid supplementation. Ojeda ML, etal., Alcohol Alcohol. 2012 Jul-Aug;47(4):404-12. doi: 10.1093/alcalc/ags056. Epub 2012 May 17.
110. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
111. Oxidative stress in patients with scalp seborrheic dermatitis. Ozturk P, etal., Acta Dermatovenerol Croat. 2013 Aug;21(2):80-5.
112. Melatonin protects against oxidative damage in a neonatal rat model of bronchopulmonary dysplasia. Pan L, etal., World J Pediatr. 2009 Aug;5(3):216-21. Epub 2009 Aug 20.
113. The activity of adenosine deaminase and oxidative stress biomarkers in scraping samples of acne lesions. Perihan O, etal., J Cosmet Dermatol. 2012 Dec;11(4):323-8. doi: 10.1111/jocd.12011.
114. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
115. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
116. Oxidative stress and endothelial dysfunction in pulmonary arteries of aged rats. Podlutsky A, etal., Am J Physiol Heart Circ Physiol. 2010 Feb;298(2):H346-51. Epub 2009 Dec 4.
117. Tobacco smoking, fruit and vegetable intake modify association between -21A>T polymorphism of catalase gene and risk of bronchial asthma. Polonikov AV, etal., J Asthma. 2009 Apr;46(3):217-24.
118. Farnesol ameliorates massive inflammation, oxidative stress and lung injury induced by intratracheal instillation of cigarette smoke extract in rats: an initial step in lung chemoprevention. Qamar W and Sultana S, Chem Biol Interact. 2008 Nov 25;176(2-3):79-87. Epub 2008 Aug 28.
119. Polyphenols from Juglans regia L. (Walnut) kernel modulate cigarette smoke extract induced acute inflammation, oxidative stress and lung injury in Wistar rats. Qamar W and Sultana S, Hum Exp Toxicol. 2010 Jun 9.
120. Long-term suppression of neurodegeneration in chronic experimental optic neuritis: antioxidant gene therapy. Qi X, etal., Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5360-70.
121. Novel 1,4-benzothazines obliterate COX-2 mediated JAK-2/STAT-3 signals with potential regulation of oxidative and metabolic stress during colorectal cancer. Rai A, etal., Pharmacol Res. 2018 Jun;132:188-203. doi: 10.1016/j.phrs.2017.12.010. Epub 2017 Dec 8.
122. Free Radical Scavenging Activity of Calotropis gigantea on Streptozotocin-Induced Diabetic Rats. Rathod NR, etal., Indian J Pharm Sci. 2009 Nov;71(6):615-21.
123. Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase. Reiners JJ Jr, etal., Carcinogenesis. 1991 Dec;12(12):2337-43.
124. Evaluating D-methionine dose to attenuate oxidative stress-mediated hearing loss following overexposure to noise. Rewerska A, etal., Eur Arch Otorhinolaryngol. 2013 Mar;270(4):1513-20. doi: 10.1007/s00405-012-2265-3. Epub 2012 Nov 18.
125. GOA pipeline RGD automated data pipeline
126. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
127. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
128. Dose dependent protection by lipoic acid against cisplatin-induced ototoxicity in rats: antioxidant defense system. Rybak LP, etal., Toxicol Sci. 1999 Feb;47(2):195-202.
129. Influence of desloratadine on selected oxidative stress markers in patients between 3 and 10 years of age with allergic perennial rhinitis. Sadowska-Woda I, etal., Eur J Pharmacol. 2010 Aug 25;640(1-3):197-201. Epub 2010 May 21.
130. Marked changes in erythrocyte antioxidants and lipid peroxidation levels of rats exposed to acute, repeated and chronic restraint stress. Sahin E, etal., Pharmazie. 2004 Dec;59(12):961-4.
131. Catalase takes part in rat liver mitochondria oxidative stress defense. Salvi M, etal., J Biol Chem. 2007 Aug 17;282(33):24407-15. Epub 2007 Jun 18.
132. Exercise modifies amphetamine relapse: behavioral and oxidative markers in rats. Segat HJ, etal., Behav Brain Res. 2014 Apr 1;262:94-100. doi: 10.1016/j.bbr.2014.01.005. Epub 2014 Jan 18.
133. A fungal Cu/Zn-containing superoxide dismutase enhances the therapeutic efficacy of a plant polyphenol extract in experimental influenza virus infection. Serkedjieva J, etal., Z Naturforsch C. 2010 May-Jun;65(5-6):419-28.
134. Effect of alcohol on blood glucose and antioxidant enzymes in the liver and kidney of diabetic rats. Shanmugam KR, etal., Indian J Pharmacol. 2011 May;43(3):330-5. doi: 10.4103/0253-7613.81504.
135. Attenuation of endogenous oxidative stress-induced cell death by cytochrome P450 inhibitors in primary cultures of rat hepatocytes. Shiba D and Shimamoto N, Free Radic Biol Med. 1999 Nov;27(9-10):1019-26.
136. Expression of catalase and glutathione peroxidase in renal insufficiency. Sindhu RK, etal., Biochim Biophys Acta. 2005 Mar 22;1743(1-2):86-92.
137. The antioxidant and antiapoptotic effect of boric acid on hepatoxicity in chronic alcohol-fed rats. Sogut I, etal., Can J Physiol Pharmacol. 2018 Apr;96(4):404-411. doi: 10.1139/cjpp-2017-0487. Epub 2017 Sep 12.
138. Determination of oxidative stress in vitiligo by measuring superoxide dismutase and catalase levels in vitiliginous and non-vitiliginous skin. Sravani PV, etal., Indian J Dermatol Venereol Leprol. 2009 May-Jun;75(3):268-71. doi: 10.4103/0378-6323.48427.
139. Oxidative stress in aging in the C57B16/J mouse cochlea. Staecker H, etal., Acta Otolaryngol. 2001 Sep;121(6):666-72.
140. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
141. Expression of hepatic antioxidant genes in l-thyroxine-induced hyperthyroid rats: regulation by vitamin E and curcumin. Subudhi U and Chainy GB, Chem Biol Interact. 2010 Jan 27;183(2):304-16. doi: 10.1016/j.cbi.2009.11.004. Epub 2009 Nov 13.
142. Upregulation of catalase and downregulation of glutathione peroxidase activity in the kidney precede the development of hypertension in pre-hypertensive SHR. Sundaram A, etal., Hypertens Res. 2013 Mar;36(3):213-8. doi: 10.1038/hr.2012.163. Epub 2012 Oct 25.
143. Acatalasemic mice are mildly susceptible to adriamycin nephropathy and exhibit increased albuminuria and glomerulosclerosis. Takiue K, etal., BMC Nephrol. 2012 Mar 25;13:14. doi: 10.1186/1471-2369-13-14.
144. CCAAT/enhancer binding protein-beta (C/EBP-beta), a pivotal regulator of the TATA-less promoter in the rat catalase gene. Taniguchi M, etal., FEBS Lett. 2005 Oct 24;579(25):5785-90. Epub 2005 Oct 6.
145. Lipid peroxidation and some antioxidant enzymes in nasal polyp tissue. Taysi S, etal., Cell Biochem Funct. 2006 Sep-Oct;24(5):461-5.
146. Oxidant/antioxidant status in men with Behcet's disease. Taysi S, etal., Clin Rheumatol. 2007 Mar;26(3):418-22. Epub 2007 Jan 6.
147. Diosmin protects rat retina from ischemia/reperfusion injury. Tong N, etal., J Ocul Pharmacol Ther. 2012 Oct;28(5):459-66. Epub 2012 Apr 17.
148. Plasma lipid peroxidation products and antioxidant enzyme activities in patients with type 2 diabetes mellitus. Turk HM, etal., Acta Diabetol. 2002 Sep;39(3):117-22.
149. Tetrahydrocurcumin ameliorates homocysteinylated cytochrome-c mediated autophagy in hyperhomocysteinemia mice after cerebral ischemia. Tyagi N, etal., J Mol Neurosci. 2012 May;47(1):128-38. doi: 10.1007/s12031-011-9695-z. Epub 2012 Jan 3.
150. The role of oxidative mechanisms in the etiopathogenesis of pterygium: a preliminary study. Ucakhan OO, etal., Ophthalmologica. 2009;223(1):41-6. doi: 10.1159/000167020. Epub 2008 Nov 4.
151. Serum and BAL cytokine and antioxidant enzyme levels at different stages of pneumoconiosis in coal workers. Ulker O, etal., Hum Exp Toxicol. 2008 Dec;27(12):871-7.
152. Increased expression of catalase and superoxide dismutase 2 reduces cone cell death in retinitis pigmentosa. Usui S, etal., Mol Ther. 2009 May;17(5):778-86. doi: 10.1038/mt.2009.47. Epub 2009 Mar 17.
153. Prolonged constriction of sciatic nerve affecting oxidative stressors & antioxidant enzymes in rat. Varija D, etal., Indian J Med Res. 2009 May;129(5):587-92.
154. Lipid peroxidation in proliferative vitreoretinopathies. Verdejo C, etal., Eye (Lond). 1999 Apr;13 ( Pt 2):183-8.
155. CYP1A1, CYP1A2 and CYBA gene polymorphisms associated with oxidative stress in COPD. Vibhuti A, etal., Clin Chim Acta. 2010 Apr 2;411(7-8):474-80. Epub 2010 Jan 18.
156. Lipid Peroxidation and Altered Anti-oxidant Status in Breast Adenocarcinoma Patients. Wang C, etal., Drug Res (Stuttg). 2014 Jul 22.
157. Over-expression of antioxidant enzymes protects cultured hippocampal and cortical neurons from necrotic insults. Wang H, etal., J Neurochem 2003 Dec;87(6):1527-34.
158. Hyperbaric oxygen preconditioning attenuates early apoptosis after spinal cord ischemia in rats. Wang L, etal., J Neurotrauma. 2009 Jan;26(1):55-66.
159. Malondialdehyde and catalase as the serum biomarkers of allyl chloride-induced toxic neuropathy. Wang QS, etal., Toxicology. 2006 Oct 3;227(1-2):36-44. Epub 2006 Jul 10.
160. 17beta-Estradiol Ameliorates Light-Induced Retinal Damage in Sprague-Dawley Rats by Reducing Oxidative Stress. Wang S, etal., J Mol Neurosci. 2014 Jul 20.
161. Molecular analysis of human acatalasemia. Identification of a splicing mutation. Wen JK, etal., J Mol Biol 1990 Jan 20;211(2):383-93.
162. Functional variants in the catalase and myeloperoxidase genes, ambient air pollution, and respiratory-related school absences: an example of epistasis in gene-environment interactions. Wenten M, etal., Am J Epidemiol. 2009 Dec 15;170(12):1494-501. Epub 2009 Nov 6.
163. Age-related cataract progression in five mouse models for anti-oxidant protection or hormonal influence. Wolf N, etal., Exp Eye Res. 2005 Sep;81(3):276-85.
164. Identification of liver proteins and their roles associated with carbon tetrachloride-induced hepatotoxicity. Wong LL, etal., Hum Exp Toxicol. 2011 Sep;30(9):1369-81. doi: 10.1177/0960327110391388. Epub 2010 Dec 7.
165. Activity of antioxidant enzymes and concentration of lipid peroxidation products in selected tissues of mice of different ages, both healthy and melanoma-bearing. Wozniak A, etal., Z Gerontol Geriatr. 2004 Jun;37(3):184-9.
166. Intraperitoneal injection of Ginkgo biloba extract enhances antioxidation ability of retina and protects photoreceptors after light-induced retinal damage in rats. Xie Z, etal., Curr Eye Res. 2007 May;32(5):471-9.
167. Antioxidant activities of Dracocephalum tanguticum maxim extract and its up-regulation on the expression of neurotrophic factors in a rat model of permanent focal cerebral ischemia. Xu JX, etal., Am J Chin Med. 2011;39(1):65-81.
168. Unilateral ureteral obstruction evokes renal tubular apoptosis via the enhanced oxidative stress and endoplasmic reticulum stress in the rat. Yeh CH, etal., Neurourol Urodyn. 2011 Mar;30(3):472-9. doi: 10.1002/nau.20855. Epub 2011 Feb 8.
169. Inducing gene expression of cardiac antioxidant enzymes by dietary phenolic acids in rats. Yeh CT, etal., J Nutr Biochem. 2009 Mar;20(3):163-71. doi: 10.1016/j.jnutbio.2008.01.005. Epub 2008 Jun 10.
170. The effects of noise on hearing and oxidative stress in textile workers. Yildirim I, etal., Ind Health. 2007 Dec;45(6):743-9.
171. The role of oxidants and antioxidants in psoriasis. Yildirim M, etal., J Eur Acad Dermatol Venereol. 2003 Jan;17(1):34-6.
172. The effect of N-acetyl serotonin on ultraviolet-radiation-induced cataracts in rats. Yildirim N, etal., Ophthalmologica. 2003 Mar-Apr;217(2):148-53.
173. Oxidative damage and antioxidant enzyme activities in experimental hypothyroidism. Yilmaz S, etal., Cell Biochem Funct 2003 Dec;21(4):325-30.
174. Effects of zinc on interleukins and antioxidant enzyme values in psoriasis-induced mice. Yin LL, etal., Biol Trace Elem Res. 2013 Dec;155(3):411-5. doi: 10.1007/s12011-013-9799-0. Epub 2013 Sep 10.
175. Adrenomedullin reduces antioxidant defense system and enhances kidney tissue damage in cadmium and lead exposed rats. Yurekli M, etal., Environ Toxicol. 2009 Jun;24(3):279-86. doi: 10.1002/tox.20430.
176. Gadolinium chloride, a kupffer cell inhibitor, attenuates hepatic injury in a rat model of chronic cholestasis. Zandieh A, etal., Hum Exp Toxicol. 2011 Feb 21.
177. Pseudoxanthoma elasticum: genetic variations in antioxidant genes are risk factors for early disease onset. Zarbock R, etal., Clin Chem. 2007 Oct;53(10):1734-40. Epub 2007 Aug 10.
178. Geldanamycin Reduces Abeta-Associated Anxiety and Depression, Concurrent with Autophagy Provocation. Zare N, etal., J Mol Neurosci. 2015 Nov;57(3):317-24. doi: 10.1007/s12031-015-0619-1. Epub 2015 Jul 25.
179. Effect of Ginkgo leaf parenteral solution on blood and cochlea antioxidant and immunity indexes in OM rats. Zhao J, etal., Molecules. 2011 Dec 15;16(12):10433-42. doi: 10.3390/molecules161210433.
180. Polymorphisms in the promoter region of catalase gene and essential hypertension. Zhou XF, etal., Dis Markers. 2005;21(1):3-7.
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Additional References at PubMed
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Genomics

Comparative Map Data
Cat
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83110,297,340 - 110,329,526 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3110,297,342 - 110,329,526 (-)EnsemblGRCr8
mRatBN7.2389,842,393 - 89,874,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl389,842,399 - 89,874,478 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx393,335,845 - 93,368,082 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03101,934,911 - 101,967,152 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0399,765,855 - 99,798,079 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0393,379,872 - 93,412,058 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl393,379,874 - 93,412,058 (-)Ensemblrn6Rnor6.0
Rnor_5.03100,021,857 - 100,054,043 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4388,654,077 - 88,686,212 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera388,911,241 - 88,943,392 (-)NCBICelera
RGSC_v3.1388,550,504 - 88,582,640 (+)NCBI
RH 3.4 Map3718.62RGD
Cytogenetic Map3q32NCBI
CAT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381134,438,934 - 34,472,060 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1134,438,906 - 34,472,061 (+)Ensemblhg38GRCh38
GRCh371134,460,481 - 34,493,607 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361134,417,054 - 34,450,183 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341134,417,053 - 34,450,179NCBI
Celera1134,607,658 - 34,640,793 (+)NCBICelera
Cytogenetic Map11p13NCBI
HuRef1134,157,829 - 34,190,968 (+)NCBIHuRef
CHM1_11134,459,461 - 34,492,601 (+)NCBICHM1_1
T2T-CHM13v2.01134,575,773 - 34,608,901 (+)NCBIT2T-CHM13v2.0
Cat
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392103,284,249 - 103,315,498 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2103,284,194 - 103,315,505 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382103,453,904 - 103,485,153 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2103,453,849 - 103,485,160 (-)Ensemblmm10GRCm38
MGSCv372103,294,061 - 103,325,310 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362103,254,842 - 103,285,959 (-)NCBIMGSCv36mm8
Celera2104,700,510 - 104,731,525 (-)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.43NCBI
Cat
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542211,781,835 - 11,827,464 (-)Ensembl
ChiLan1.0NW_00495542211,783,973 - 11,826,970 (-)NCBIChiLan1.0ChiLan1.0
CAT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2936,658,657 - 36,694,370 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11136,665,639 - 36,699,236 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01134,413,253 - 34,446,831 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11134,289,603 - 34,323,160 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1134,289,603 - 34,323,160 (+)EnsemblpanPan2panpan1.1
CAT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11833,383,005 - 33,422,447 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1833,383,005 - 33,422,447 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1832,988,826 - 33,028,342 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01833,993,703 - 34,033,703 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1833,972,087 - 34,033,763 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11833,553,399 - 33,593,082 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01833,145,251 - 33,185,159 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01833,780,645 - 33,820,629 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494730,476,191 - 30,512,340 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365333,600,955 - 3,637,422 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365333,601,270 - 3,637,128 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl226,487,653 - 26,581,452 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1226,493,664 - 26,533,881 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2228,860,864 - 28,900,834 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap2p16-p15NCBI
CAT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1130,792,533 - 30,828,920 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl130,792,399 - 30,829,592 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038127,903,025 - 127,939,181 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cat
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476712,680,953 - 12,715,739 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476712,680,940 - 12,715,468 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cat
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1581,288,678 - 81,319,821 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cat
156 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:414
Count of miRNA genes:228
Interacting mature miRNAs:259
Transcripts:ENSRNOT00000011230
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)373592611110333156Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat

Markers in Region
D3Mit7  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83110,333,156 - 110,333,321 (+)Marker Load Pipeline
mRatBN7.2389,878,207 - 89,878,372 (+)MAPPERmRatBN7.2
Rnor_6.0393,415,673 - 93,415,837NCBIRnor6.0
Rnor_5.03100,057,451 - 100,057,615UniSTSRnor5.0
RGSC_v3.4388,648,420 - 88,648,585RGDRGSC3.4
RGSC_v3.4388,648,421 - 88,648,585UniSTSRGSC3.4
Celera388,947,023 - 88,947,189UniSTS
RGSC_v3.1388,544,848 - 88,545,013RGD
RH 3.4 Map3719.51UniSTS
RH 3.4 Map3719.51RGD
RH 2.0 Map3461.0RGD
FHH x ACI Map353.96RGD
Cytogenetic Map3q32-q34UniSTS
D3Arb10  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83110,331,010 - 110,331,321 (+)Marker Load Pipeline
Rnor_6.0393,413,543 - 93,413,837NCBIRnor6.0
Celera388,944,877 - 88,945,187UniSTS
RH 3.4 Map3716.91UniSTS
RH 3.4 Map3716.91RGD
SHRSP x BN Map346.7498RGD
SHRSP x BN Map346.7498UniSTS
FHH x ACI Map353.96RGD
Cytogenetic Map3q32-q34UniSTS
D3Hmgc1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.03100,055,227 - 100,055,344NCBIRnor5.0
RGSC_v3.4388,652,647 - 88,652,843RGDRGSC3.4
RGSC_v3.4388,652,648 - 88,652,843UniSTSRGSC3.4
Celera388,944,577 - 88,944,772UniSTS
RH 3.4 Map3717.41RGD
RH 3.4 Map3717.41UniSTS
Cytogenetic Map3q32-q34UniSTS
RH94469  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83110,297,656 - 110,297,806 (+)Marker Load Pipeline
mRatBN7.2389,842,709 - 89,842,859 (+)MAPPERmRatBN7.2
Rnor_6.0393,380,189 - 93,380,338NCBIRnor6.0
Rnor_5.03100,022,174 - 100,022,323UniSTSRnor5.0
RGSC_v3.4388,685,748 - 88,685,897UniSTSRGSC3.4
Celera388,911,558 - 88,911,707UniSTS
RH 3.4 Map3718.62UniSTS
Cytogenetic Map3q32-q34UniSTS
AW535533  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2389,847,000 - 89,847,179 (+)MAPPERmRatBN7.2
Rnor_6.0393,384,480 - 93,384,658NCBIRnor6.0
Rnor_5.03100,026,465 - 100,026,643UniSTSRnor5.0
RGSC_v3.4388,681,428 - 88,681,606UniSTSRGSC3.4
Celera388,915,849 - 88,916,027UniSTS
RH 3.4 Map3716.81UniSTS
Cytogenetic Map3q32-q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000011230   ⟹   ENSRNOP00000011230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3110,297,342 - 110,329,526 (-)Ensembl
mRatBN7.2 Ensembl389,842,399 - 89,874,478 (-)Ensembl
Rnor_6.0 Ensembl393,379,874 - 93,412,058 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120007   ⟹   ENSRNOP00000092755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3110,297,342 - 110,329,526 (-)Ensembl
mRatBN7.2 Ensembl389,842,399 - 89,874,478 (-)Ensembl
RefSeq Acc Id: NM_012520   ⟹   NP_036652
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83110,297,340 - 110,329,526 (-)NCBI
mRatBN7.2389,842,393 - 89,874,577 (-)NCBI
Rnor_6.0393,379,872 - 93,412,058 (-)NCBI
Rnor_5.03100,021,857 - 100,054,043 (-)NCBI
RGSC_v3.4388,654,077 - 88,686,212 (+)RGD
Celera388,911,241 - 88,943,392 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_036652 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40884 (Get FASTA)   NCBI Sequence Viewer  
  AAB42378 (Get FASTA)   NCBI Sequence Viewer  
  AAH81853 (Get FASTA)   NCBI Sequence Viewer  
  EDL79666 (Get FASTA)   NCBI Sequence Viewer  
  EDL79667 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011230
  ENSRNOP00000011230.4
GenBank Protein P04762 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_036652   ⟸   NM_012520
- UniProtKB: P04762 (UniProtKB/Swiss-Prot),   A6HNR6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011230   ⟸   ENSRNOT00000011230
Ensembl Acc Id: ENSRNOP00000092755   ⟸   ENSRNOT00000120007
Protein Domains
Catalase core

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P04762-F1-model_v2 AlphaFold P04762 1-527 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692253
Promoter ID:EPDNEW_R2778
Type:initiation region
Name:Cat_1
Description:catalase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0393,411,993 - 93,412,053EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2279 AgrOrtholog
BioCyc Gene G2FUF-48577 BioCyc
BioCyc Pathway DETOX1-PWY [superoxide radicals degradation] BioCyc
  DETOX1-PWY-1 [reactive oxygen species degradation] BioCyc
  PWY66-162 [ethanol degradation IV] BioCyc
BioCyc Pathway Image DETOX1-PWY BioCyc
  DETOX1-PWY-1 BioCyc
  PWY66-162 BioCyc
Ensembl Genes ENSRNOG00000008364 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011230 ENTREZGENE
  ENSRNOT00000011230.6 UniProtKB/Swiss-Prot
Gene3D-CATH Catalase core domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7109889 IMAGE-MGC_LOAD
InterPro Catalase UniProtKB/Swiss-Prot
  Catalase_3 UniProtKB/Swiss-Prot
  Catalase_AS UniProtKB/Swiss-Prot
  Catalase_clade1/3 UniProtKB/Swiss-Prot
  Catalase_core UniProtKB/Swiss-Prot
  Catalase_haem_BS UniProtKB/Swiss-Prot
  Catalase_immune_responsive UniProtKB/Swiss-Prot
  Catalase_sf UniProtKB/Swiss-Prot
KEGG Report rno:24248 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93644 IMAGE-MGC_LOAD
NCBI Gene 24248 ENTREZGENE
PANTHER CATALASE UniProtKB/Swiss-Prot
  PTHR11465 UniProtKB/Swiss-Prot
Pfam Catalase UniProtKB/Swiss-Prot
  Catalase-rel UniProtKB/Swiss-Prot
PhenoGen Cat PhenoGen
PIRSF Catalase_clade1-3 UniProtKB/Swiss-Prot
PRINTS CATALASE UniProtKB/Swiss-Prot
PROSITE CATALASE_1 UniProtKB/Swiss-Prot
  CATALASE_2 UniProtKB/Swiss-Prot
  CATALASE_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008364 RatGTEx
SMART Catalase UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56634 UniProtKB/Swiss-Prot
UniProt A0A8I6AH65_RAT UniProtKB/TrEMBL
  A6HNR5_RAT UniProtKB/TrEMBL
  A6HNR6 ENTREZGENE, UniProtKB/TrEMBL
  CATA_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Cat  Catalase      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in liver 634701
gene_process functions as a hydrogen peroxide:hydrogen peroxide oxidoreductase 634701
gene_transcript 33 kb 634701