Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Wdr46 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of WDR46 mRNA] | CTD | PMID:31150632 | Wdr46 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Wdr46 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of WDR46 mRNA | CTD | PMID:22206623 | Wdr46 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Wdr46 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of WDR46 mRNA | CTD | PMID:17942748 | Wdr46 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Wdr46 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of WDR46 mRNA | CTD | PMID:17942748 | Wdr46 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Wdr46 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of WDR46 mRNA | CTD | PMID:17555576 | Wdr46 | Rat | 17beta-estradiol | increases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Estradiol results in increased expression of WDR46 mRNA | CTD | PMID:31614463 | Wdr46 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Wdr46 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of WDR46 mRNA | CTD | PMID:17942748 | Wdr46 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Wdr46 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of WDR46 mRNA | CTD | PMID:21570461 | Wdr46 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Wdr46 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of WDR46 mRNA | CTD | PMID:17942748 | Wdr46 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of WDR46 mRNA | CTD | PMID:21346803 | Wdr46 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of WDR46 mRNA | CTD | PMID:30851411 | Wdr46 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | WDR46 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Wdr46 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Wdr46 (Mus musculus) | 6480464 | bisphenol S results in increased expression of WDR46 mRNA | CTD | PMID:39298647 | Wdr46 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Wdr46 (Mus musculus) | 6480464 | bisphenol S affects the methylation of WDR46 gene | CTD | PMID:31683443 | Wdr46 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Wdr46 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of WDR46 exon | CTD | PMID:33297965 | Wdr46 | Rat | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2,6-dinitrotoluene affects the expression of WDR46 mRNA | CTD | PMID:21346803 | Wdr46 | Rat | aflatoxin B1 | increases mutagenesis | EXP | | 6480464 | Aflatoxin B1 results in increased mutagenesis of WDR46 gene | CTD | PMID:36908029 | Wdr46 | Rat | aflatoxin B1 | multiple interactions | ISO | WDR46 (Homo sapiens) | 6480464 | [Aflatoxin B1 co-treated with beta-Naphthoflavone] results in decreased expression of WDR46 protein | CTD | PMID:39638853 | Wdr46 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of WDR46 mRNA | CTD | PMID:16483693 | Wdr46 | Rat | aristolochic acid A | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of WDR46 protein | CTD | PMID:33212167 | Wdr46 | Rat | atrazine | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of WDR46 mRNA | CTD | PMID:22378314 | Wdr46 | Rat | benzalkonium chloride | affects response to substance | ISO | WDR46 (Homo sapiens) | 6480464 | WDR46 SNP affects the susceptibility to Benzalkonium Compounds | CTD | PMID:27258892 | Wdr46 | Rat | benzo[a]pyrene | decreases methylation | ISO | WDR46 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of WDR46 exon | CTD | PMID:27901495 | Wdr46 | Rat | beta-lapachone | increases expression | ISO | WDR46 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of WDR46 mRNA | CTD | PMID:38218311 | Wdr46 | Rat | beta-naphthoflavone | multiple interactions | ISO | WDR46 (Homo sapiens) | 6480464 | [Aflatoxin B1 co-treated with beta-Naphthoflavone] results in decreased expression of WDR46 protein | CTD | PMID:39638853 | Wdr46 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of WDR46 mRNA | CTD | PMID:25181051 | Wdr46 | Rat | bisphenol A | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of WDR46 protein | CTD | PMID:32981897 | Wdr46 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of WDR46 mRNA | CTD | PMID:33296240 | Wdr46 | Rat | bisphenol F | multiple interactions | ISO | WDR46 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Wdr46 | Rat | cadmium atom | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Cadmium results in decreased expression of WDR46 mRNA | CTD | PMID:23369406 | Wdr46 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of WDR46 promoter | CTD | PMID:22457795 | Wdr46 | Rat | cadmium dichloride | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of WDR46 mRNA | CTD | PMID:38174414 | Wdr46 | Rat | carbon nanotube | increases expression | ISO | Wdr46 (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of WDR46 mRNA | CTD | PMID:25554681 | Wdr46 | Rat | cisplatin | affects response to substance | ISO | WDR46 (Homo sapiens) | 6480464 | WDR46 protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 | Wdr46 | Rat | cisplatin | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of WDR46 mRNA | CTD | PMID:27594783 | Wdr46 | Rat | clobetasol | increases expression | ISO | Wdr46 (Mus musculus) | 6480464 | Clobetasol results in increased expression of WDR46 mRNA | CTD | PMID:27462272 | Wdr46 | Rat | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of WDR46 mRNA | CTD | PMID:17602206 | Wdr46 | Rat | cyclosporin A | increases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of WDR46 mRNA | CTD | PMID:20106945 | Wdr46 | Rat | deoxynivalenol | increases expression | ISO | WDR46 (Homo sapiens) | 6480464 | deoxynivalenol results in increased expression of WDR46 protein | CTD | PMID:39638853 | Wdr46 | Rat | dexamethasone | multiple interactions | ISO | WDR46 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Wdr46 | Rat | Dibutyl phosphate | affects expression | ISO | WDR46 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of WDR46 mRNA | CTD | PMID:37042841 | Wdr46 | Rat | dimethyl sulfoxide | increases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Dimethyl Sulfoxide results in increased expression of WDR46 mRNA | CTD | PMID:39709020 | Wdr46 | Rat | epoxiconazole | decreases expression | ISO | Wdr46 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of WDR46 mRNA | CTD | PMID:35436446 | Wdr46 | Rat | ethyl methanesulfonate | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of WDR46 mRNA | CTD | PMID:23649840 | Wdr46 | Rat | flusilazole | affects expression | ISO | Wdr46 (Mus musculus) | 6480464 | flusilazole affects the expression of WDR46 mRNA | CTD | PMID:21195148 | Wdr46 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of WDR46 mRNA | CTD | PMID:24136188 | Wdr46 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of WDR46 mRNA | CTD | PMID:24793618 | Wdr46 | Rat | folic acid | multiple interactions | ISO | Wdr46 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of WDR46 mRNA | CTD | PMID:22206623 | Wdr46 | Rat | FR900359 | increases phosphorylation | ISO | WDR46 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of WDR46 protein | CTD | PMID:37730182 | Wdr46 | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of WDR46 gene | CTD | PMID:22079235 | Wdr46 | Rat | hexaconazole | affects expression | ISO | Wdr46 (Mus musculus) | 6480464 | hexaconazole affects the expression of WDR46 mRNA | CTD | PMID:21195148 | Wdr46 | Rat | hydralazine | multiple interactions | ISO | WDR46 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of WDR46 mRNA | CTD | PMID:17183730 | Wdr46 | Rat | indometacin | multiple interactions | ISO | WDR46 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Wdr46 | Rat | methyl methanesulfonate | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of WDR46 mRNA | CTD | PMID:23649840 | Wdr46 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of WDR46 mRNA | CTD | PMID:17602206 | Wdr46 | Rat | Nivalenol | increases expression | ISO | WDR46 (Homo sapiens) | 6480464 | nivalenol results in increased expression of WDR46 protein | CTD | PMID:39638853 | Wdr46 | Rat | ochratoxin A | decreases expression | EXP | | 6480464 | ochratoxin A results in decreased expression of WDR46 mRNA | CTD | PMID:22124623 | Wdr46 | Rat | ozone | multiple interactions | ISO | Wdr46 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... | CTD | PMID:34911549 | Wdr46 | Rat | paracetamol | affects expression | ISO | Wdr46 (Mus musculus) | 6480464 | Acetaminophen affects the expression of WDR46 mRNA | CTD | PMID:17562736 | Wdr46 | Rat | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of WDR46 mRNA | CTD | PMID:32680482 | Wdr46 | Rat | perfluorononanoic acid | increases expression | ISO | WDR46 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of WDR46 mRNA | CTD | PMID:32588087 | Wdr46 | Rat | rac-lactic acid | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of WDR46 mRNA | CTD | PMID:30851411 | Wdr46 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of WDR46 mRNA | CTD | PMID:28374803 | Wdr46 | Rat | sodium arsenate | decreases expression | ISO | Wdr46 (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of WDR46 mRNA | CTD | PMID:30953684 | Wdr46 | Rat | sodium arsenite | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of WDR46 mRNA | CTD | PMID:38568856 | Wdr46 | Rat | tamoxifen | affects expression | ISO | Wdr46 (Mus musculus) | 6480464 | Tamoxifen affects the expression of WDR46 mRNA | CTD | PMID:17555576 | Wdr46 | Rat | temozolomide | increases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of WDR46 mRNA | CTD | PMID:31758290 | Wdr46 | Rat | testosterone enanthate | affects expression | ISO | WDR46 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of WDR46 mRNA | CTD | PMID:17440010 | Wdr46 | Rat | tetrachloromethane | affects expression | ISO | Wdr46 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of WDR46 mRNA | CTD | PMID:17484886 | Wdr46 | Rat | tetrachloromethane | increases expression | ISO | Wdr46 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of WDR46 mRNA | CTD | PMID:31919559 | Wdr46 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of WDR46 mRNA] | CTD | PMID:31150632 | Wdr46 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of WDR46 mRNA | CTD | PMID:31150632 | Wdr46 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of WDR46 mRNA | CTD | PMID:23411599|PMID:34492290 | Wdr46 | Rat | thiram | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Thiram results in decreased expression of WDR46 mRNA | CTD | PMID:38568856 | Wdr46 | Rat | titanium dioxide | decreases methylation | ISO | Wdr46 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of WDR46 gene | CTD | PMID:35295148 | Wdr46 | Rat | triadimefon | affects expression | ISO | Wdr46 (Mus musculus) | 6480464 | triadimefon affects the expression of WDR46 mRNA | CTD | PMID:21195148 | Wdr46 | Rat | urethane | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Urethane results in decreased expression of WDR46 mRNA | CTD | PMID:28818685 | Wdr46 | Rat | valproic acid | increases methylation | ISO | WDR46 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of WDR46 gene | CTD | PMID:29154799 | Wdr46 | Rat | valproic acid | affects expression | ISO | WDR46 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of WDR46 mRNA | CTD | PMID:25979313 | Wdr46 | Rat | valproic acid | increases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of WDR46 mRNA | CTD | PMID:23179753 | Wdr46 | Rat | valproic acid | multiple interactions | ISO | WDR46 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of WDR46 mRNA | CTD | PMID:17183730 | Wdr46 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of WDR46 mRNA | CTD | PMID:22570695|PMID:23869203 | Wdr46 | Rat | zinc atom | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Zinc results in decreased expression of WDR46 mRNA | CTD | PMID:15226459 | Wdr46 | Rat | zinc sulfate | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Zinc Sulfate results in decreased expression of WDR46 mRNA | CTD | PMID:15226459 | Wdr46 | Rat | zinc(0) | decreases expression | ISO | WDR46 (Homo sapiens) | 6480464 | Zinc results in decreased expression of WDR46 mRNA | CTD | PMID:15226459 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















