WDR46 (WD repeat domain 46) - Rat Genome Database

Name: WDR46
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: WDR46 (WD repeat domain 46) Homo sapiens

Analyze

Symbol:

WDR46

Name:

WD repeat domain 46

RGD ID:

1353590

HGNC Page

HGNC:13923

Description:

Enables RNA binding activity. Involved in ribosomal small subunit biogenesis. Located in nucleolus. Part of small-subunit processome.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

BING4; C6orf11; chromosome 6 open reading frame 11; FP221; UTP7; WD repeat-containing protein 46; WD repeat-containing protein BING4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Wdr46 (WD repeat domain 46)	HGNC	Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Wdr46 (WD repeat domain 46)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Chinchilla lanigera (long-tailed chinchilla):	Wdr46 (WD repeat domain 46)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	WDR46 (WD repeat domain 46)	NCBI	Ortholog
Canis lupus familiaris (dog):	WDR46 (WD repeat domain 46)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Wdr46 (WD repeat domain 46)	NCBI	Ortholog
Sus scrofa (pig):	WDR46 (WD repeat domain 46)	HGNC	Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Chlorocebus sabaeus (green monkey):	WDR46 (WD repeat domain 46)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Wdr46 (WD repeat domain 46)	NCBI	Ortholog
Other homologs ²
Sus scrofa (pig):	RGL2 (ral guanine nucleotide dissociation stimulator like 2)	HGNC	EggNOG
Rattus norvegicus (Norway rat):	Mid1ip1 (MID1 interacting protein 1)	HGNC	OMA
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Wdr46 (WD repeat domain 46)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Wdr46 (WD repeat domain 46)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	wdr46 (WD repeat domain 46)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	CG2260	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	UTP7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	wdr-46	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus laevis (African clawed frog):	wdr46.S	Alliance	DIOPT (Xenbase)
Xenopus tropicalis (tropical clawed frog):	wdr46	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus laevis (African clawed frog):	wdr46.L	Alliance	DIOPT (Xenbase)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	33,279,108 - 33,289,239 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	33,279,108 - 33,289,247 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	33,246,885 - 33,257,016 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	33,354,863 - 33,364,969 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	33,354,863 - 33,364,969	NCBI
Celera	6	34,801,238 - 34,811,662 (-)	NCBI		Celera
Cytogenetic Map	6	p21.32	NCBI
HuRef	6	32,988,537 - 32,998,938 (-)	NCBI		HuRef
CHM1_1	6	33,248,816 - 33,259,244 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	33,100,470 - 33,110,601 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant intellectual developmental disorder 5 (IAGP)

Disease Progression (EXP)

proteasome-associated autoinflammatory syndrome 1 (IAGP)

Stomach Neoplasms (EXP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (ISO)

2-hydroxypropanoic acid (EXP)

3-isobutyl-1-methyl-7H-xanthine (EXP)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (ISO)

aflatoxin B1 (ISO)

ammonium chloride (ISO)

aristolochic acid A (EXP)

atrazine (EXP)

benzalkonium chloride (EXP)

benzo[a]pyrene (EXP)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

cadmium atom (EXP)

cadmium dichloride (ISO)

carbon nanotube (ISO)

cisplatin (EXP)

clobetasol (ISO)

clofibric acid (ISO)

cyclosporin A (EXP)

dexamethasone (EXP)

epoxiconazole (ISO)

ethyl methanesulfonate (EXP)

flusilazole (ISO)

flutamide (ISO)

folic acid (ISO)

FR900359 (EXP)

furan (ISO)

hexaconazole (ISO)

hydralazine (EXP)

indometacin (EXP)

methyl methanesulfonate (EXP)

N-nitrosodiethylamine (ISO)

ochratoxin A (ISO)

ozone (ISO)

paracetamol (ISO)

paraquat (ISO)

perfluorononanoic acid (EXP)

rac-lactic acid (EXP)

rotenone (ISO)

sodium arsenate (ISO)

tamoxifen (ISO)

temozolomide (EXP)

testosterone enanthate (EXP)

tetrachloromethane (ISO)

thioacetamide (ISO)

triadimefon (ISO)

urethane (EXP)

valproic acid (EXP)

vinclozolin (ISO)

zinc atom (EXP)

zinc sulfate (EXP)

zinc(0) (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (IBA,IEA)

ribosomal small subunit biogenesis (IDA)

Cellular Component

90S preribosome (IEA)

collagen trimer (IEA)

nucleolus (IBA,IDA,IEA)

nucleoplasm (TAS)

nucleus (IEA)

ribosome (IEA)

small-subunit processome (IBA,IDA,IEA)

Molecular Function

RNA binding (HDA)

References

References - curated

#	Reference Title	Reference Citation
1.	TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC.	Herberg JA, etal., J Mol Biol 1998 Apr 10;277(4):839-57.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9521053	PMID:11790298	PMID:12477932	PMID:14574404	PMID:15342556	PMID:15489334	PMID:15498874	PMID:15635413	PMID:16344560	PMID:16565220	PMID:19851445	PMID:21873635
PMID:22586326	PMID:22658674	PMID:22681889	PMID:22754713	PMID:23848194	PMID:24270810	PMID:24457600	PMID:24711643	PMID:24754225	PMID:24981860	PMID:25665578	PMID:25693804
PMID:26344197	PMID:26496610	PMID:26949251	PMID:27926873	PMID:28514442	PMID:28986522	PMID:29117863	PMID:29395067	PMID:29467282	PMID:29955894	PMID:30021884	PMID:30463901
PMID:30948266	PMID:31091453	PMID:31363146	PMID:31586073	PMID:33961781	PMID:34079125	PMID:34373451	PMID:34516797	PMID:34732716	PMID:35509820	PMID:35652658	PMID:35681168
PMID:35944360	PMID:36215168	PMID:36232890	PMID:36424410	PMID:36574265	PMID:36912080	PMID:37827155	PMID:38172120

Genomics

Comparative Map Data

WDR46
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	33,279,108 - 33,289,239 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	33,279,108 - 33,289,247 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	33,246,885 - 33,257,016 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	33,354,863 - 33,364,969 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	33,354,863 - 33,364,969	NCBI
Celera	6	34,801,238 - 34,811,662 (-)	NCBI		Celera
Cytogenetic Map	6	p21.32	NCBI
HuRef	6	32,988,537 - 32,998,938 (-)	NCBI		HuRef
CHM1_1	6	33,248,816 - 33,259,244 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	33,100,470 - 33,110,601 (-)	NCBI		T2T-CHM13v2.0

Wdr46
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	34,159,608 - 34,168,669 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	34,159,634 - 34,168,671 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	33,940,634 - 33,949,695 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	33,940,660 - 33,949,697 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	34,077,668 - 34,086,640 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	33,551,177 - 33,560,149 (+)	NCBI		MGSCv36	mm8
Celera	17	36,693,635 - 36,702,594 (+)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	17.98	NCBI

Wdr46
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	4,939,721 - 4,947,619 (-)	NCBI		GRCr8
mRatBN7.2	20	4,937,845 - 4,945,796 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	4,937,847 - 4,946,535 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	5,661,367 - 5,669,100 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	5,023,112 - 5,030,845 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	5,503,899 - 5,511,638 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	5,447,860 - 5,455,632 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	5,447,860 - 5,455,632 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	7,506,472 - 7,514,244 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	5,089,611 - 5,097,383 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	5,089,839 - 5,097,610 (-)	NCBI
Celera	20	6,522,088 - 6,529,834 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

Wdr46
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	1,840,791 - 1,848,172 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	1,840,875 - 1,848,258 (-)	NCBI	ChiLan1.0	ChiLan1.0

WDR46
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	47,756,943 - 47,767,149 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	43,628,607 - 43,638,816 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	32,851,335 - 32,861,806 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	33,965,528 - 33,975,898 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	33,965,528 - 33,975,898 (-)	Ensembl	panpan1.1		panPan2

WDR46
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	2,721,262 - 2,729,365 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	2,720,658 - 2,729,394 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	2,802,170 - 2,810,395 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	3,052,429 - 3,060,890 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	3,052,450 - 3,060,598 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	2,719,901 - 2,728,119 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	2,801,391 - 2,809,605 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	2,876,085 - 2,884,317 (-)	NCBI		UU_Cfam_GSD_1.0

Wdr46
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	38,373,210 - 38,383,152 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	25,577,243 - 25,586,931 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	25,577,115 - 25,587,057 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

WDR46
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	29,645,130 - 29,653,579 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	29,645,128 - 29,653,567 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	34,148,893 - 34,157,252 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

WDR46
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	38,787,932 - 38,797,940 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	38,788,275 - 38,799,858 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	33,114,052 - 33,124,178 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Wdr46
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	23,532,771 - 23,541,975 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	23,532,579 - 23,542,109 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in WDR46
26 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
NM_001164267.1(WDR46):c.718-63C>T	single nucleotide variant	Lung cancer [RCV000096829]	Chr6:33287289 [GRCh38] Chr6:33255066 [GRCh37] Chr6:6p21.32	uncertain significance
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3	copy number gain	See cases [RCV000143497]	Chr6:156974..46789291 [GRCh38] Chr6:156974..46757028 [GRCh37] Chr6:101974..46864987 [NCBI36] Chr6:6p25.3-12.3	pathogenic
GRCh37/hg19 6p21.32(chr6:33256191-33400523)x3	copy number gain	Breast ductal adenocarcinoma [RCV000207216]	Chr6:33256191..33400523 [GRCh37] Chr6:6p21.32	uncertain significance
NC_000006.11:g.(?_33131435)_(33419703_?)dup	duplication	Intellectual disability, autosomal dominant 5 [RCV000817954]	Chr6:33163658..33451926 [GRCh38] Chr6:33131435..33419703 [GRCh37] Chr6:6p21.32	uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3	copy number gain	See cases [RCV000512067]	Chr6:156975..170919482 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)	copy number gain	See cases [RCV000510595]	Chr6:156975..170919482 [GRCh37] Chr6:6p25.3-q27	pathogenic
NM_005452.6(WDR46):c.1778C>T (p.Ala593Val)	single nucleotide variant	not specified [RCV004295698]	Chr6:33279331 [GRCh38] Chr6:33247108 [GRCh37] Chr6:6p21.32	uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3	copy number gain	not provided [RCV000745403]	Chr6:108666..170980171 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3	copy number gain	not provided [RCV000745400]	Chr6:60107..171054786 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3	copy number gain	not provided [RCV000745404]	Chr6:165632..170919470 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367)	copy number gain	not provided [RCV000767714]	Chr6:29455465..81447367 [GRCh37] Chr6:6p22.1-q14.1	pathogenic
NM_005452.6(WDR46):c.841C>T (p.Leu281Phe)	single nucleotide variant	not specified [RCV004284522]	Chr6:33287393 [GRCh38] Chr6:33255170 [GRCh37] Chr6:6p21.32	uncertain significance
NC_000006.12:g.(?_33173681)_(33451926_?)dup	duplication	Intellectual disability, autosomal dominant 5 [RCV001032258]	Chr6:33141458..33419703 [GRCh37] Chr6:6p21.32	uncertain significance
GRCh37/hg19 6p21.33-21.31(chr6:31036397-34088832)x3	copy number gain	not provided [RCV001005791]	Chr6:31036397..34088832 [GRCh37] Chr6:6p21.33-21.31	likely pathogenic
GRCh37/hg19 6p21.32-21.31(chr6:33069892-33751391)	copy number gain	not specified [RCV002053566]	Chr6:33069892..33751391 [GRCh37] Chr6:6p21.32-21.31	uncertain significance
NC_000006.11:g.(?_30695893)_(36953949_?)dup	duplication	Proteasome-associated autoinflammatory syndrome 1 [RCV003113679]	Chr6:30695893..36953949 [GRCh37] Chr6:6p21.33-21.2	uncertain significance
NM_005452.6(WDR46):c.926T>C (p.Ile309Thr)	single nucleotide variant	not specified [RCV004200347]	Chr6:33287180 [GRCh38] Chr6:33254957 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.673G>A (p.Val225Ile)	single nucleotide variant	not specified [RCV004113676]	Chr6:33287669 [GRCh38] Chr6:33255446 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1435G>A (p.Gly479Ser)	single nucleotide variant	not specified [RCV004078953]	Chr6:33280517 [GRCh38] Chr6:33248294 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1781A>G (p.Lys594Arg)	single nucleotide variant	not specified [RCV004117259]	Chr6:33279328 [GRCh38] Chr6:33247105 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1334G>A (p.Arg445Gln)	single nucleotide variant	not specified [RCV004127775]	Chr6:33280769 [GRCh38] Chr6:33248546 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.371C>T (p.Ser124Phe)	single nucleotide variant	not specified [RCV004091364]	Chr6:33288460 [GRCh38] Chr6:33256237 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1013A>G (p.Asn338Ser)	single nucleotide variant	not specified [RCV004103586]	Chr6:33287093 [GRCh38] Chr6:33254870 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.661G>A (p.Ala221Thr)	single nucleotide variant	not specified [RCV004126412]	Chr6:33287681 [GRCh38] Chr6:33255458 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.878C>T (p.Ala293Val)	single nucleotide variant	not specified [RCV004205916]	Chr6:33287356 [GRCh38] Chr6:33255133 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.491A>T (p.Asp164Val)	single nucleotide variant	not specified [RCV004104065]	Chr6:33288218 [GRCh38] Chr6:33255995 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.470C>T (p.Pro157Leu)	single nucleotide variant	not specified [RCV004211445]	Chr6:33288361 [GRCh38] Chr6:33256138 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1556G>A (p.Arg519Gln)	single nucleotide variant	not specified [RCV004223911]	Chr6:33279828 [GRCh38] Chr6:33247605 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1723G>A (p.Glu575Lys)	single nucleotide variant	not specified [RCV004115829]	Chr6:33279508 [GRCh38] Chr6:33247285 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.794A>G (p.Gln265Arg)	single nucleotide variant	not specified [RCV004103103]	Chr6:33287440 [GRCh38] Chr6:33255217 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1199T>C (p.Leu400Pro)	single nucleotide variant	not specified [RCV004167813]	Chr6:33280904 [GRCh38] Chr6:33248681 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.817C>T (p.Arg273Cys)	single nucleotide variant	not specified [RCV004231732]	Chr6:33287417 [GRCh38] Chr6:33255194 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1801C>G (p.Arg601Gly)	single nucleotide variant	not specified [RCV004076719]	Chr6:33279308 [GRCh38] Chr6:33247085 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.806T>C (p.Leu269Pro)	single nucleotide variant	not specified [RCV004135228]	Chr6:33287428 [GRCh38] Chr6:33255205 [GRCh37] Chr6:6p21.32	uncertain significance
NC_000006.11:g.(?_32148920)_(36953949_?)dup	duplication	not provided [RCV003154914]	Chr6:32148920..36953949 [GRCh37] Chr6:6p21.32-21.2	uncertain significance
NM_005452.6(WDR46):c.1771A>G (p.Lys591Glu)	single nucleotide variant	not specified [RCV004285087]	Chr6:33279338 [GRCh38] Chr6:33247115 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.644G>A (p.Arg215His)	single nucleotide variant	not specified [RCV004255132]	Chr6:33287698 [GRCh38] Chr6:33255475 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1775A>C (p.Glu592Ala)	single nucleotide variant	not specified [RCV004285088]	Chr6:33279334 [GRCh38] Chr6:33247111 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1801C>T (p.Arg601Trp)	single nucleotide variant	not specified [RCV004275195]	Chr6:33279308 [GRCh38] Chr6:33247085 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1376A>C (p.Glu459Ala)	single nucleotide variant	not specified [RCV004351736]	Chr6:33280727 [GRCh38] Chr6:33248504 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1127C>T (p.Thr376Ile)	single nucleotide variant	not specified [RCV004480492]	Chr6:33280976 [GRCh38] Chr6:33248753 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1250C>T (p.Ala417Val)	single nucleotide variant	not specified [RCV004480493]	Chr6:33280853 [GRCh38] Chr6:33248630 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.151C>G (p.Arg51Gly)	single nucleotide variant	not specified [RCV004480494]	Chr6:33288932 [GRCh38] Chr6:33256709 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1640A>G (p.Lys547Arg)	single nucleotide variant	not specified [RCV004480495]	Chr6:33279591 [GRCh38] Chr6:33247368 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.1752C>G (p.Ser584Arg)	single nucleotide variant	not specified [RCV004480496]	Chr6:33279357 [GRCh38] Chr6:33247134 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.599G>A (p.Arg200Lys)	single nucleotide variant	not specified [RCV004480497]	Chr6:33287989 [GRCh38] Chr6:33255766 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.838C>T (p.Arg280Trp)	single nucleotide variant	not specified [RCV004480498]	Chr6:33287396 [GRCh38] Chr6:33255173 [GRCh37] Chr6:6p21.32	uncertain significance
NM_005452.6(WDR46):c.964G>A (p.Val322Ile)	single nucleotide variant	not specified [RCV004480499]	Chr6:33287142 [GRCh38] Chr6:33254919 [GRCh37] Chr6:6p21.32	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	2429
Count of miRNA genes:	881
Interacting mature miRNAs:	1093
Transcripts:	ENST00000374617, ENST00000444176, ENST00000461951, ENST00000468157, ENST00000473611, ENST00000477718, ENST00000481025, ENST00000488944, ENST00000489905
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

G43302

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	33,246,416 - 33,246,602	UniSTS	GRCh37
Build 36	6	33,354,394 - 33,354,580	RGD	NCBI36
Celera	6	34,800,774 - 34,800,960	RGD
Cytogenetic Map	6	p21.3	UniSTS
HuRef	6	32,988,073 - 32,988,259	UniSTS

SHGC-170354

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	33,252,353 - 33,252,702	UniSTS	GRCh37
Build 36	6	33,360,331 - 33,360,680	RGD	NCBI36
Celera	6	34,806,711 - 34,807,060	RGD
Cytogenetic Map	6	p21.3	UniSTS
HuRef	6	32,994,010 - 32,994,359	UniSTS
TNG Radiation Hybrid Map	6	18551.0	UniSTS

D6S1234E

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	33,254,896 - 33,254,997	UniSTS	GRCh37
Build 36	6	33,362,874 - 33,362,975	RGD	NCBI36
Celera	6	34,809,254 - 34,809,355	RGD
Cytogenetic Map	6	p21.3	UniSTS
HuRef	6	32,996,530 - 32,996,631	UniSTS
GeneMap99-GB4 RH Map	6	119.82	UniSTS
NCBI RH Map	6	509.1	UniSTS

HSC0YF092

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	33,246,886 - 33,247,160	UniSTS	GRCh37
Build 36	6	33,354,864 - 33,355,138	RGD	NCBI36
Celera	6	34,801,244 - 34,801,518	RGD
Cytogenetic Map	6	p21.3	UniSTS
HuRef	6	32,988,543 - 32,988,817	UniSTS
GeneMap99-GB4 RH Map	6	119.38	UniSTS
GeneMap99-GB4 RH Map	6	120.03	UniSTS
Whitehead-RH Map	6	179.8	UniSTS
NCBI RH Map	6	509.1	UniSTS

RH12439

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	33,246,903 - 33,247,080	UniSTS	GRCh37
Build 36	6	33,354,881 - 33,355,058	RGD	NCBI36
Celera	6	34,801,261 - 34,801,438	RGD
Cytogenetic Map	6	p21.3	UniSTS
HuRef	6	32,988,560 - 32,988,737	UniSTS
GeneMap99-GB4 RH Map	6	120.03	UniSTS
NCBI RH Map	6	509.1	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

visual system

adipose tissue

appendage

entire extraembryonic component

pharyngeal arch

High

Medium

2428

2405

1653

555

1722

397

4303

1876

2958

381

1455

1606

172

1204

2734

Low

586

229

321

776

Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001164267	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_005452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017011484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017011485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017011486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017011487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047419523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047419524	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054329929	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054329930	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054330422	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054330423	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054330915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054330916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054331194	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054331195	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054331196	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054331197	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054356755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054356756	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001743743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002956316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF447870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AI867295	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK292171	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK292616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK297925	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK298151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK308534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK311388	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK315616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL031228	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL662820	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL662827	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL844527	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC000388	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BP344599	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX000343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX439421	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CR759786	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CR759817	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DB272479	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KY500741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KY500742	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KY500743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KY500744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Z97184	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000374617 ⟹ ENSP00000363746

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	6	33,279,108 - 33,289,239 (-)	Ensembl

RefSeq Acc Id:

ENST00000444176 ⟹ ENSP00000405568

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	6	33,280,916 - 33,288,887 (-)	Ensembl

RefSeq Acc Id:

ENST00000461951

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	6	33,279,108 - 33,280,911 (-)	Ensembl

RefSeq Acc Id:

ENST00000468157

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	6	33,287,664 - 33,289,202 (-)	Ensembl

RefSeq Acc Id:

ENST00000473611

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	6	33,279,108 - 33,280,851 (-)	Ensembl

RefSeq Acc Id:

ENST00000477718

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	6	33,287,492 - 33,289,247 (-)	Ensembl

RefSeq Acc Id:

ENST00000481025

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	6	33,288,056 - 33,289,012 (-)	Ensembl

RefSeq Acc Id:

ENST00000488944

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	6	33,287,243 - 33,288,026 (-)	Ensembl

RefSeq Acc Id:

ENST00000489905

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	6	33,279,571 - 33,287,429 (-)	Ensembl

RefSeq Acc Id:

NM_001164267 ⟹ NP_001157739

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	33,279,108 - 33,289,239 (-)	NCBI
GRCh37	6	33,246,682 - 33,257,304 (-)	NCBI
Celera	6	34,801,238 - 34,811,662 (-)	RGD
HuRef	6	32,988,537 - 32,998,938 (-)	RGD
CHM1_1	6	33,248,816 - 33,259,244 (-)	NCBI
T2T-CHM13v2.0	6	33,100,470 - 33,110,601 (-)	NCBI

Sequence:

show sequence

GAGTTTTCAAGCCGACTGTGTGGCAGCTGAGAGGAGTTTTGCACGTGGATCGCCGTTCGGGTGG
GCGAGATGGAGACAGCCCCCAAGCCGGGCAAGGATGTCCCGCCCAAGAAAGACAAACTTCAGAC
CAAGAGAAAGAAACCCCGAGAATGGAAGAACCCGGAGTCCCAGCGCGGCTTGTCCGGGACCCAA
GATCCATTCCCAGGCCCCGCCCCCGTCCCTGTGGAAGTGGTCCAGAAGTTCTGTCGCATTGACA
AATCCCGAAAGCTACCACATTCTAAAGCCAAAACTCGAAGCCGACTTGAGGTGGCTGAAGCTGA
GGAAGAGGAAACAAGTATCAAAGCTGCTCGTTCTGAGCTGCTGCTTGCTGAAGAACCTGGGTTT
CTGGAAGGGGAGGATGGGGAAGACACAGCAAAGATATGCCAGGCTGACATTGTGGAGGCTGTGG
ACATTGCAAGTGCAGCCAAGCACTTTGACTTGAATCTGCGGCAGTTTGGACCCTACAGACTAAA
CTACTCTCGAACTGGAAGACACCTGGCTTTTGGAGGGCGCCGAGGTCATGTGGCTGCCCTTGAT
TGGGTAACAAAGAAGCTTATGTGCGAGATCAACGTCATGGAGGCGGTGCGGGACATCCGGTTTC
TCCATTCTGAGGCACTGCTTGCTGTTGCTCAGAACCGCTGGCTCCACATCTATGACAATCAGGG
CATTGAGCTCCACTGTATCCGCCGCTGTGACCGAGTAACACGGCTTGAGTTCCTGCCCTTCCAC
TTCCTCCTGGCTACAGCTTCAGAAACAGGGTTTCTAACCTACCTGGATGTGTCAGTGGGGAAGA
TTGTGGCAGCTCTGAATGCTCGAGCTGGGCGGCTCGATGTTATGAGTCAGAACCCTTACAATGC
CGTCATCCATCTCGGACACAGCAATGGTACTGTGTCTTTATGGAGTCCAGCTATGAAGGAGCCA
CTGGCAAAGATTCTCTGTCATCGTGGTGGGGTCCGGGCTGTGGCAGTAGATTCTACAGGCACGT
ACATGGCCACCTCTGGCCTAGACCACCAGCTGAAGATCTTTGACTTGCGAGGGACGTACCAGCC
TCTGAGCACTCGGACCCTGCCCCATGGAGCAGGGCACCTGGCCTTCTCCCAGAGGGGACTGCTG
GTGGCGGGAATGGGTGACGTTGTCAACATCTGGGCAGGGCAGGGCAAGGCCAGCCCACCCTCCC
TTGAACAGCCCTACCTCACCCACCGGCTCTCAGGCCCTGTGCATGGCCTTCAGTTCTGCCCCTT
TGAAGATGTGCTGGGGGTGGGGCACACTGGGGGCATCACCAGCATGCTGGTCCCTGGGGCCGGT
GAGCCCAACTTCGATGGCCTGGAGAGTAATCCATACAGAAGCCGGAAGCAGCGCCAGGAGTGGG
AGGTGAAGGCCCTGCTAGAGAAGGTACCTGCAGAGCTTATTTGTCTGGACCCACGAGCCCTGGC
CGAGGTGGATGTCATCTCCCTGGAGCAGGGAAAGAAGGAGCAGATAGAGAGGCTGGGCTATGAC
CCGCAGGCTAAGGCTCCCTTCCAGCCAAAGCCAAAGCAGAAGGGCCGCAGCTCCACGGCAAGCC
TGGTGAAGAGGAAGAGGAAGGTCATGGATGAGGAACACAGGGACAAGGTCCGGCAGAGCCTTCA
GCAGCAGCATCATAAGGAGGCGAAGGCCAAGCCCACGGGGGCCCGGCCATCTGCCCTGGACAGA
TTTGTGCGCTGAGCCAGACTCCAGGGTTGCCTGGGAACAGTCTCTCCCCAAGATCACCTGTAGG
GAAATGAGTGTTCCCTGGAACAAGGAGGTGGGGGCAGTGTGGCCCCTTCCCCAACTGGGGGTGG
ACAGCTGTCTCCTGGGGTGGGTTGGTATTAAAGAGGAAAGCGATTTTTTGGA

hide sequence

RefSeq Acc Id:

NM_005452 ⟹ NP_005443

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	33,279,108 - 33,289,239 (-)	NCBI
GRCh37	6	33,246,682 - 33,257,304 (-)	NCBI
Build 36	6	33,354,863 - 33,364,969 (-)	NCBI Archive
Celera	6	34,801,238 - 34,811,662 (-)	RGD
HuRef	6	32,988,537 - 32,998,938 (-)	RGD
CHM1_1	6	33,248,816 - 33,259,244 (-)	NCBI
T2T-CHM13v2.0	6	33,100,470 - 33,110,601 (-)	NCBI

Sequence:

show sequence

GAGTTTTCAAGCCGACTGTGTGGCAGCTGAGAGGAGTTTTGCACGTGGATCGCCGTTCGGGTGG
GCGAGATGGAGACAGCCCCCAAGCCGGGCAAGGATGTCCCGCCCAAGAAAGACAAACTTCAGAC
CAAGAGAAAGAAACCGCGGCGATACTGGGAGGAAGAGACCGTTCCGACCACAGCCGGAGCCTCT
CCAGGGCCTCCTCGTAACAAGAAGAATCGGGAGCTCCGTCCTCAGAGACCAAAAAATGCTTACA
TCTTAAAGAAGTCTCGGATCTCTAAGAAGCCTCAGGTCCCGAAGAAACCCCGAGAATGGAAGAA
CCCGGAGTCCCAGCGCGGCTTGTCCGGGACCCAAGATCCATTCCCAGGCCCCGCCCCCGTCCCT
GTGGAAGTGGTCCAGAAGTTCTGTCGCATTGACAAATCCCGAAAGCTACCACATTCTAAAGCCA
AAACTCGAAGCCGACTTGAGGTGGCTGAAGCTGAGGAAGAGGAAACAAGTATCAAAGCTGCTCG
TTCTGAGCTGCTGCTTGCTGAAGAACCTGGGTTTCTGGAAGGGGAGGATGGGGAAGACACAGCA
AAGATATGCCAGGCTGACATTGTGGAGGCTGTGGACATTGCAAGTGCAGCCAAGCACTTTGACT
TGAATCTGCGGCAGTTTGGACCCTACAGACTAAACTACTCTCGAACTGGAAGACACCTGGCTTT
TGGAGGGCGCCGAGGTCATGTGGCTGCCCTTGATTGGGTAACAAAGAAGCTTATGTGCGAGATC
AACGTCATGGAGGCGGTGCGGGACATCCGGTTTCTCCATTCTGAGGCACTGCTTGCTGTTGCTC
AGAACCGCTGGCTCCACATCTATGACAATCAGGGCATTGAGCTCCACTGTATCCGCCGCTGTGA
CCGAGTAACACGGCTTGAGTTCCTGCCCTTCCACTTCCTCCTGGCTACAGCTTCAGAAACAGGG
TTTCTAACCTACCTGGATGTGTCAGTGGGGAAGATTGTGGCAGCTCTGAATGCTCGAGCTGGGC
GGCTCGATGTTATGAGTCAGAACCCTTACAATGCCGTCATCCATCTCGGACACAGCAATGGTAC
TGTGTCTTTATGGAGTCCAGCTATGAAGGAGCCACTGGCAAAGATTCTCTGTCATCGTGGTGGG
GTCCGGGCTGTGGCAGTAGATTCTACAGGCACGTACATGGCCACCTCTGGCCTAGACCACCAGC
TGAAGATCTTTGACTTGCGAGGGACGTACCAGCCTCTGAGCACTCGGACCCTGCCCCATGGAGC
AGGGCACCTGGCCTTCTCCCAGAGGGGACTGCTGGTGGCGGGAATGGGTGACGTTGTCAACATC
TGGGCAGGGCAGGGCAAGGCCAGCCCACCCTCCCTTGAACAGCCCTACCTCACCCACCGGCTCT
CAGGCCCTGTGCATGGCCTTCAGTTCTGCCCCTTTGAAGATGTGCTGGGGGTGGGGCACACTGG
GGGCATCACCAGCATGCTGGTCCCTGGGGCCGGTGAGCCCAACTTCGATGGCCTGGAGAGTAAT
CCATACAGAAGCCGGAAGCAGCGCCAGGAGTGGGAGGTGAAGGCCCTGCTAGAGAAGGTACCTG
CAGAGCTTATTTGTCTGGACCCACGAGCCCTGGCCGAGGTGGATGTCATCTCCCTGGAGCAGGG
AAAGAAGGAGCAGATAGAGAGGCTGGGCTATGACCCGCAGGCTAAGGCTCCCTTCCAGCCAAAG
CCAAAGCAGAAGGGCCGCAGCTCCACGGCAAGCCTGGTGAAGAGGAAGAGGAAGGTCATGGATG
AGGAACACAGGGACAAGGTCCGGCAGAGCCTTCAGCAGCAGCATCATAAGGAGGCGAAGGCCAA
GCCCACGGGGGCCCGGCCATCTGCCCTGGACAGATTTGTGCGCTGAGCCAGACTCCAGGGTTGC
CTGGGAACAGTCTCTCCCCAAGATCACCTGTAGGGAAATGAGTGTTCCCTGGAACAAGGAGGTG
GGGGCAGTGTGGCCCCTTCCCCAACTGGGGGTGGACAGCTGTCTCCTGGGGTGGGTTGGTATTA
AAGAGGAAAGCGATTTTTTGGA

hide sequence

RefSeq Acc Id:

XM_047419523 ⟹ XP_047275479

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	33,279,108 - 33,289,239 (-)	NCBI

RefSeq Acc Id:

XM_047419524 ⟹ XP_047275480

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	33,280,862 - 33,289,239 (-)	NCBI

RefSeq Acc Id:

XM_054356755 ⟹ XP_054212730

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	6	33,100,470 - 33,110,601 (-)	NCBI

RefSeq Acc Id:

XM_054356756 ⟹ XP_054212731

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	6	33,102,096 - 33,110,601 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001157739	(Get FASTA)	NCBI Sequence Viewer
	NP_005443	(Get FASTA)	NCBI Sequence Viewer
	XP_047275479	(Get FASTA)	NCBI Sequence Viewer
	XP_047275480	(Get FASTA)	NCBI Sequence Viewer
	XP_054185904	(Get FASTA)	NCBI Sequence Viewer
	XP_054185905	(Get FASTA)	NCBI Sequence Viewer
	XP_054186397	(Get FASTA)	NCBI Sequence Viewer
	XP_054186398	(Get FASTA)	NCBI Sequence Viewer
	XP_054186890	(Get FASTA)	NCBI Sequence Viewer
	XP_054186891	(Get FASTA)	NCBI Sequence Viewer
	XP_054187169	(Get FASTA)	NCBI Sequence Viewer
	XP_054187170	(Get FASTA)	NCBI Sequence Viewer
	XP_054187171	(Get FASTA)	NCBI Sequence Viewer
	XP_054187172	(Get FASTA)	NCBI Sequence Viewer
	XP_054212730	(Get FASTA)	NCBI Sequence Viewer
	XP_054212731	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH00388	(Get FASTA)	NCBI Sequence Viewer
	AAQ04645	(Get FASTA)	NCBI Sequence Viewer
	AQY77211	(Get FASTA)	NCBI Sequence Viewer
	AQY77212	(Get FASTA)	NCBI Sequence Viewer
	AQY77213	(Get FASTA)	NCBI Sequence Viewer
	AQY77214	(Get FASTA)	NCBI Sequence Viewer
	BAF84860	(Get FASTA)	NCBI Sequence Viewer
	BAF85305	(Get FASTA)	NCBI Sequence Viewer
	BAG37984	(Get FASTA)	NCBI Sequence Viewer
	BAG60242	(Get FASTA)	NCBI Sequence Viewer
	BAG60427	(Get FASTA)	NCBI Sequence Viewer
	CAA20229	(Get FASTA)	NCBI Sequence Viewer
	CAB09994	(Get FASTA)	NCBI Sequence Viewer
	EAX03701	(Get FASTA)	NCBI Sequence Viewer
	EAX03702	(Get FASTA)	NCBI Sequence Viewer
	EAX03703	(Get FASTA)	NCBI Sequence Viewer
	EAX03704	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000363746
	ENSP00000363746.4
	ENSP00000372695.4
	ENSP00000399454.2
	ENSP00000402869.2
	ENSP00000405568.1
	ENSP00000405614.2
	ENSP00000406835.1
	ENSP00000407066.1
	ENSP00000408651.1
	ENSP00000412069.1
GenBank Protein	O15213	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_005443 ⟸ NM_005452
- Peptide Label:	isoform 1
- UniProtKB:	Q5STK5 (UniProtKB/Swiss-Prot), Q5HYZ0 (UniProtKB/Swiss-Prot), A6NDP5 (UniProtKB/Swiss-Prot), Q5STR3 (UniProtKB/Swiss-Prot), O15213 (UniProtKB/Swiss-Prot), B0UZZ8 (UniProtKB/TrEMBL), E7EM79 (UniProtKB/TrEMBL)
- Sequence:	show sequence METAPKPGKDVPPKKDKLQTKRKKPRRYWEEETVPTTAGASPGPPRNKKNRELRPQRPKNAYIL KKSRISKKPQVPKKPREWKNPESQRGLSGTQDPFPGPAPVPVEVVQKFCRIDKSRKLPHSKAKT RSRLEVAEAEEEETSIKAARSELLLAEEPGFLEGEDGEDTAKICQADIVEAVDIASAAKHFDLN LRQFGPYRLNYSRTGRHLAFGGRRGHVAALDWVTKKLMCEINVMEAVRDIRFLHSEALLAVAQN RWLHIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATASETGFLTYLDVSVGKIVAALNARAGRL DVMSQNPYNAVIHLGHSNGTVSLWSPAMKEPLAKILCHRGGVRAVAVDSTGTYMATSGLDHQLK IFDLRGTYQPLSTRTLPHGAGHLAFSQRGLLVAGMGDVVNIWAGQGKASPPSLEQPYLTHRLSG PVHGLQFCPFEDVLGVGHTGGITSMLVPGAGEPNFDGLESNPYRSRKQRQEWEVKALLEKVPAE LICLDPRALAEVDVISLEQGKKEQIERLGYDPQAKAPFQPKPKQKGRSSTASLVKRKRKVMDEE HRDKVRQSLQQQHHKEAKAKPTGARPSALDRFVR hide sequence

RefSeq Acc Id:	NP_001157739 ⟸ NM_001164267
- Peptide Label:	isoform 2
- UniProtKB:	A0A1U9X8W1 (UniProtKB/TrEMBL), A0A1U9X8U7 (UniProtKB/TrEMBL)
- Sequence:	show sequence METAPKPGKDVPPKKDKLQTKRKKPREWKNPESQRGLSGTQDPFPGPAPVPVEVVQKFCRIDKS RKLPHSKAKTRSRLEVAEAEEEETSIKAARSELLLAEEPGFLEGEDGEDTAKICQADIVEAVDI ASAAKHFDLNLRQFGPYRLNYSRTGRHLAFGGRRGHVAALDWVTKKLMCEINVMEAVRDIRFLH SEALLAVAQNRWLHIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATASETGFLTYLDVSVGKIV AALNARAGRLDVMSQNPYNAVIHLGHSNGTVSLWSPAMKEPLAKILCHRGGVRAVAVDSTGTYM ATSGLDHQLKIFDLRGTYQPLSTRTLPHGAGHLAFSQRGLLVAGMGDVVNIWAGQGKASPPSLE QPYLTHRLSGPVHGLQFCPFEDVLGVGHTGGITSMLVPGAGEPNFDGLESNPYRSRKQRQEWEV KALLEKVPAELICLDPRALAEVDVISLEQGKKEQIERLGYDPQAKAPFQPKPKQKGRSSTASLV KRKRKVMDEEHRDKVRQSLQQQHHKEAKAKPTGARPSALDRFVR hide sequence

RefSeq Acc Id:

ENSP00000363746 ⟸ ENST00000374617

RefSeq Acc Id:

ENSP00000405568 ⟸ ENST00000444176

RefSeq Acc Id:	XP_047275479 ⟸ XM_047419523
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_047275480 ⟸ XM_047419524
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_054212730 ⟸ XM_054356755
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_054212731 ⟸ XM_054356756
- Peptide Label:	isoform X2

Protein Domains

BING4 C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O15213-F1-model_v2	AlphaFold	O15213	1-610	view protein structure

Promoters

RGD ID:

6872852

Promoter ID:

EPDNEW_H9591

Type:

initiation region

Name:

WDR46_1

Description:

WD repeat domain 46

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	33,289,226 - 33,289,286	EPDNEW

RGD ID:

6805007

Promoter ID:

HG_KWN:53186

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, HeLa_S3, Lymphoblastoid, NB4

Transcripts:

OTTHUMT00000076383, OTTHUMT00000076386, OTTHUMT00000276304

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	6	33,356,351 - 33,357,287 (-)	MPROMDB

RGD ID:

6804154

Promoter ID:

HG_KWN:53188

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, HeLa_S3, K562, Lymphoblastoid, NB4

Transcripts:

ENST00000374606, ENST00000374610, ENST00000395134, NM_001164267, NM_005452, NM_014260, OTTHUMT00000076387, OTTHUMT00000076388, OTTHUMT00000076521, OTTHUMT00000076522, OTTHUMT00000276301, OTTHUMT00000276302, UC010JUO.1, UC010JUP.1, UC010JUQ.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	6	33,364,821 - 33,366,162 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:13923	AgrOrtholog
COSMIC	WDR46	COSMIC
Ensembl Genes	ENSG00000204221	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSG00000206284	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSG00000226916	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSG00000227057	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSG00000236222	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENST00000374617	ENTREZGENE
	ENST00000374617.9	UniProtKB/Swiss-Prot
	ENST00000383208.8	UniProtKB/Swiss-Prot
	ENST00000416777.1	UniProtKB/TrEMBL
	ENST00000432609.6	UniProtKB/Swiss-Prot
	ENST00000432933.6	UniProtKB/Swiss-Prot
	ENST00000443102.1	UniProtKB/TrEMBL
	ENST00000444176.1	UniProtKB/TrEMBL
	ENST00000450918.1	UniProtKB/TrEMBL
	ENST00000456332.1	UniProtKB/TrEMBL
	ENST00000457382.6	UniProtKB/Swiss-Prot
Gene3D-CATH	2.130.10.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000204221	GTEx
	ENSG00000206284	GTEx
	ENSG00000226916	GTEx
	ENSG00000227057	GTEx
	ENSG00000236222	GTEx
HGNC ID	HGNC:13923	ENTREZGENE
Human Proteome Map	WDR46	Human Proteome Map
InterPro	BING4_C_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WDR46/Utp7	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:9277	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	9277	ENTREZGENE
OMIM	611440	OMIM
PANTHER	PTHR14085	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD REPEAT-CONTAINING PROTEIN 46	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	BING4CT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA25924	PharmGKB
PROSITE	WD_REPEATS_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	BING4CT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF50978	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JJL1_HUMAN	UniProtKB/TrEMBL
	A0A140T9L0_HUMAN	UniProtKB/TrEMBL
	A0A1U9X8U7	ENTREZGENE, UniProtKB/TrEMBL
	A0A1U9X8W1	ENTREZGENE, UniProtKB/TrEMBL
	A6NDP5	ENTREZGENE
	A8K806_HUMAN	UniProtKB/TrEMBL
	B0UZZ8	ENTREZGENE, UniProtKB/TrEMBL
	B4DP15_HUMAN	UniProtKB/TrEMBL
	E7EM79	ENTREZGENE
	H0Y6G3_HUMAN	UniProtKB/TrEMBL
	O15213	ENTREZGENE
	Q5HYZ0	ENTREZGENE
	Q5STK5	ENTREZGENE
	Q5STR3	ENTREZGENE
	WDR46_HUMAN	UniProtKB/Swiss-Prot
UniProt Secondary	A6NDP5	UniProtKB/Swiss-Prot
	E7EM79	UniProtKB/TrEMBL
	Q5HYZ0	UniProtKB/Swiss-Prot
	Q5STK5	UniProtKB/Swiss-Prot
	Q5STR3	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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