1,1'-azobis(N,N-dimethylformamide) multiple interactions ISO ATP7A (Homo sapiens) 6480464 Diamide promotes the reaction [CLU protein binds to ATP7A protein] CTD PMID:21242307 1,1-dichloroethene increases expression ISO Atp7a (Mus musculus) 6480464 vinylidene chloride results in increased expression of ATP7A mRNA CTD PMID:26682919 1,2-dimethylhydrazine multiple interactions EXP 6480464 [APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in increased expression of ATP7A mRNA CTD PMID:27840820 1,2-dimethylhydrazine multiple interactions ISO Atp7a (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP7A mRNA CTD PMID:22206623 1,4-dithiothreitol multiple interactions ISO ATP7A (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [Ethylmaleimide results in increased glutathionylation of ATP7A protein] CTD PMID:20566629 17alpha-ethynylestradiol multiple interactions ISO Atp7a (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATP7A mRNA CTD PMID:17942748 17alpha-ethynylestradiol decreases expression ISO Atp7a (Mus musculus) 6480464 Ethinyl Estradiol results in decreased expression of ATP7A mRNA and Ethinyl Estradiol results in decreased expression of ATP7A protein CTD PMID:27690074 17alpha-ethynylestradiol increases expression ISO Atp7a (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of ATP7A mRNA CTD PMID:17942748 2,2,2-tetramine increases expression EXP 6480464 Trientine results in increased expression of ATP7A mRNA and Trientine results in increased expression of ATP7A protein CTD PMID:24927960 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Atp7a (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATP7A mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of ATP7A mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Atp7a (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of ATP7A mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Atp7a (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ATP7A mRNA CTD PMID:19770486 and PMID:33956508 2-hydroxypropanoic acid decreases expression ISO ATP7A (Homo sapiens) 6480464 Lactic Acid results in decreased expression of ATP7A mRNA CTD PMID:30851411 3,4-methylenedioxymethamphetamine decreases expression ISO Atp7a (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of ATP7A mRNA CTD PMID:20188158 and PMID:26251327 4,4'-sulfonyldiphenol decreases methylation ISO Atp7a (Mus musculus) 6480464 bisphenol S results in decreased methylation of ATP7A exon CTD PMID:33297965 4-hydroxy-TEMPO multiple interactions ISO Atp7a (Mus musculus) 6480464 tempol inhibits the reaction [ATP7A mutant form inhibits the reaction [AGT protein results in increased susceptibility to Acetylcholine]] and tempol inhibits the reaction [ATP7A mutant form promotes the reaction [AGT protein results in increased abundance of Superoxides]] CTD PMID:18768397 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions ISO ATP7A (Homo sapiens) 6480464 Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein] CTD PMID:25337692 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions ISO Atp7a (Mus musculus) 6480464 Omeprazole inhibits the reaction [Copper affects the localization of ATP7A protein] and Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein] CTD PMID:25337692 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of ATP7A mRNA CTD PMID:22504374 acetamide increases expression EXP 6480464 acetamide results in increased expression of ATP7A mRNA CTD PMID:31881176 acetylcholine multiple interactions ISO Atp7a (Mus musculus) 6480464 ATP7A mutant form inhibits the reaction [AGT protein results in increased susceptibility to Acetylcholine] and tempol inhibits the reaction [ATP7A mutant form inhibits the reaction [AGT protein results in increased susceptibility to Acetylcholine]] CTD PMID:18768397 aflatoxin B1 decreases methylation ISO ATP7A (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of ATP7A gene CTD PMID:27153756 Aflatoxin B2 alpha increases methylation ISO ATP7A (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of ATP7A intron CTD PMID:30157460 all-trans-retinoic acid increases expression ISO ATP7A (Homo sapiens) 6480464 Tretinoin results in increased expression of ATP7A mRNA CTD PMID:16012519 and PMID:21934132 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ATP7A mRNA CTD PMID:16483693 aristolochic acid A decreases expression ISO ATP7A (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of ATP7A mRNA CTD PMID:33212167 arsenous acid decreases expression ISO Atp7a (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of ATP7A mRNA CTD PMID:35676786 ATP multiple interactions ISO ATP7A (Homo sapiens) 6480464 [Copper co-treated with Adenosine Triphosphate] results in increased phosphorylation of ATP7A protein CTD PMID:20964302 atrazine decreases expression ISO ATP7A (Homo sapiens) 6480464 Atrazine results in decreased expression of ATP7A mRNA CTD PMID:22378314 bathocuproine disulfonic acid multiple interactions ISO ATP7A (Homo sapiens) 6480464 [Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7A protein] more ... CTD PMID:11092760 and PMID:21242307 benzo[a]pyrene increases expression ISO Atp7a (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of ATP7A mRNA CTD PMID:20504355 and PMID:22228805 benzo[a]pyrene increases methylation ISO ATP7A (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of ATP7A exon CTD PMID:27901495 benzo[a]pyrene affects methylation ISO ATP7A (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of ATP7A promoter CTD PMID:27901495 benzo[e]pyrene affects methylation ISO ATP7A (Homo sapiens) 6480464 benzo(e)pyrene affects the methylation of ATP7A intron CTD PMID:30157460 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ATP7A mRNA CTD PMID:25181051 bisphenol A increases expression ISO ATP7A (Homo sapiens) 6480464 bisphenol A results in increased expression of ATP7A mRNA CTD PMID:29275510 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ATP7A mRNA CTD PMID:30816183 and PMID:34947998 bisphenol A decreases expression ISO Atp7a (Mus musculus) 6480464 bisphenol A results in decreased expression of ATP7A mRNA and bisphenol A results in decreased expression of ATP7A protein CTD PMID:27690074 brefeldin A multiple interactions ISO ATP7A (Homo sapiens) 6480464 Brefeldin A inhibits the reaction [ATP7A protein affects the localization of Doxorubicin] CTD PMID:17510416 butanal decreases expression ISO ATP7A (Homo sapiens) 6480464 butyraldehyde results in decreased expression of ATP7A mRNA CTD PMID:26079696 cadmium atom decreases expression ISO ATP7A (Homo sapiens) 6480464 Cadmium results in decreased expression of ATP7A mRNA CTD PMID:24376830 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of ATP7A mRNA and Cadmium results in increased expression of ATP7A protein CTD PMID:32879253 cadmium dichloride decreases expression ISO Atp7a (Mus musculus) 6480464 Cadmium Chloride results in decreased expression of ATP7A mRNA CTD PMID:24982889 carboplatin affects localization ISO ATP7A (Homo sapiens) 6480464 Carboplatin affects the localization of ATP7A protein CTD PMID:24150977 carboplatin multiple interactions ISO ATP7A (Homo sapiens) 6480464 [MIR495 mRNA results in decreased expression of ATP7A protein] which results in increased susceptibility to Carboplatin and ATP7A protein promotes the reaction [ANXA4 protein results in decreased susceptibility to Carboplatin] CTD PMID:24038379 and PMID:24150977 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of ATP7A mRNA CTD PMID:23125180 chromium(6+) decreases expression ISO ATP7A (Homo sapiens) 6480464 chromium hexavalent ion results in decreased expression of ATP7A mRNA CTD PMID:30690063 cisplatin decreases response to substance ISO Atp7a (Mus musculus) 6480464 ATP7A protein results in decreased susceptibility to Cisplatin CTD PMID:16170571 cisplatin affects localization ISO ATP7A (Homo sapiens) 6480464 Cisplatin affects the localization of ATP7A protein CTD PMID:24150977 cisplatin multiple interactions ISO ATP7A (Homo sapiens) 6480464 [ATOX1 protein binds to Cisplatin] promotes the reaction [ATP7A protein binds to and results in increased metabolism of Cisplatin] more ... CTD PMID:23751120 more ... cisplatin affects response to substance ISO ATP7A (Homo sapiens) 6480464 ATP7A protein affects the susceptibility to Cisplatin CTD PMID:17609664 cisplatin decreases response to substance ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in decreased susceptibility to Cisplatin CTD PMID:17510416 and PMID:25801007 cisplatin increases response to substance ISO ATP7A (Homo sapiens) 6480464 ATP7A mutant form results in increased susceptibility to Cisplatin CTD PMID:22304828 cisplatin increases expression ISO Atp7a (Mus musculus) 6480464 Cisplatin results in increased expression of ATP7A mRNA CTD PMID:21151649 cobalt dichloride increases expression ISO ATP7A (Homo sapiens) 6480464 cobaltous chloride results in increased expression of ATP7A mRNA CTD PMID:24614111 cobalt dichloride multiple interactions EXP 6480464 Plicamycin inhibits the reaction [cobaltous chloride results in increased expression of ATP7A mRNA] CTD PMID:23814049 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of ATP7A mRNA CTD PMID:23814049 copper atom affects metabolic processing ISO ATP7A (Homo sapiens) 6480464 ATP7A protein affects the metabolism of Copper CTD PMID:16890543 copper atom affects localization ISO ATP7A (Homo sapiens) 6480464 Copper affects the localization of ATP7A protein CTD PMID:20964302 and PMID:23423674 copper atom decreases abundance ISO Atp7a (Mus musculus) 6480464 ATP7A gene mutant form results in decreased abundance of Copper more ... CTD PMID:21336677 more ... copper atom increases transport EXP 6480464 ATP7A protein results in increased transport of Copper CTD PMID:24614235 copper atom affects localization EXP 6480464 Copper affects the localization of ATP7A protein CTD PMID:20671235 and PMID:24614235 copper atom decreases export EXP 6480464 ATP7A mutant form results in decreased export of Copper CTD PMID:24316150 copper atom affects export ISO Atp7a (Mus musculus) 6480464 ATP7A protein affects the export of Copper CTD PMID:21409224 copper atom increases export ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in increased export of Copper CTD PMID:16397091 more ... copper atom increases abundance ISO ATP7A (Homo sapiens) 6480464 ATP7A gene mutant form results in increased abundance of Copper CTD PMID:15923132 copper atom decreases abundance ISO ATP7A (Homo sapiens) 6480464 ATP7A gene mutant form results in decreased abundance of Copper more ... CTD PMID:11350187 more ... copper atom multiple interactions ISO Atp7a (Mus musculus) 6480464 [ATP7A gene mutant form co-treated with Iron deficiency] results in increased uptake of Copper more ... CTD PMID:15467011 more ... copper atom increases abundance ISO Atp7a (Mus musculus) 6480464 ATP7A gene mutant form results in increased abundance of Copper CTD PMID:15467011 copper atom affects localization ISO Atp7a (Mus musculus) 6480464 ATP7A gene mutant form affects the localization of Copper and Copper affects the localization of ATP7A protein CTD PMID:17483305 more ... copper atom increases transport ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in increased transport of Copper CTD PMID:21667063 copper atom increases expression EXP 6480464 Copper results in increased expression of ATP7A mRNA CTD PMID:15591161 copper atom multiple interactions EXP 6480464 [Iron deficiency results in increased expression of ATP7A] which results in increased abundance of Copper and PRL protein promotes the reaction [ATP7A protein results in increased secretion of Copper] CTD PMID:16741141 and PMID:24174620 copper atom increases secretion EXP 6480464 ATP7A protein results in increased secretion of Copper CTD PMID:16741141 copper atom affects transport ISO ATP7A (Homo sapiens) 6480464 ATP7A protein affects the transport of Copper CTD PMID:17109627 copper atom affects binding ISO ATP7A (Homo sapiens) 6480464 ATP7A protein binds to Copper and Copper binds to ATP7A protein CTD PMID:16873374 and PMID:22577880 copper atom multiple interactions ISO ATP7A (Homo sapiens) 6480464 [ATP7A protein affects the oxidation of SCO1 protein] which affects the abundance of Copper more ... CTD PMID:10841766 more ... copper(0) affects metabolic processing ISO ATP7A (Homo sapiens) 6480464 ATP7A protein affects the metabolism of Copper CTD PMID:16890543 copper(0) affects localization ISO ATP7A (Homo sapiens) 6480464 Copper affects the localization of ATP7A protein CTD PMID:20964302 and PMID:23423674 copper(0) decreases abundance ISO Atp7a (Mus musculus) 6480464 ATP7A gene mutant form results in decreased abundance of Copper more ... CTD PMID:21336677 more ... copper(0) increases transport EXP 6480464 ATP7A protein results in increased transport of Copper CTD PMID:24614235 copper(0) affects localization EXP 6480464 Copper affects the localization of ATP7A protein CTD PMID:20671235 and PMID:24614235 copper(0) decreases export EXP 6480464 ATP7A mutant form results in decreased export of Copper CTD PMID:24316150 copper(0) affects export ISO Atp7a (Mus musculus) 6480464 ATP7A protein affects the export of Copper CTD PMID:21409224 copper(0) increases export ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in increased export of Copper CTD PMID:16397091 more ... copper(0) increases abundance ISO ATP7A (Homo sapiens) 6480464 ATP7A gene mutant form results in increased abundance of Copper CTD PMID:15923132 copper(0) decreases abundance ISO ATP7A (Homo sapiens) 6480464 ATP7A gene mutant form results in decreased abundance of Copper more ... CTD PMID:11350187 more ... copper(0) multiple interactions ISO Atp7a (Mus musculus) 6480464 [ATP7A gene mutant form co-treated with Iron deficiency] results in increased uptake of Copper more ... CTD PMID:15467011 more ... copper(0) increases abundance ISO Atp7a (Mus musculus) 6480464 ATP7A gene mutant form results in increased abundance of Copper CTD PMID:15467011 copper(0) affects localization ISO Atp7a (Mus musculus) 6480464 ATP7A gene mutant form affects the localization of Copper and Copper affects the localization of ATP7A protein CTD PMID:17483305 more ... copper(0) increases transport ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in increased transport of Copper CTD PMID:21667063 copper(0) increases expression EXP 6480464 Copper results in increased expression of ATP7A mRNA CTD PMID:15591161 copper(0) multiple interactions EXP 6480464 [Iron deficiency results in increased expression of ATP7A] which results in increased abundance of Copper and PRL protein promotes the reaction [ATP7A protein results in increased secretion of Copper] CTD PMID:16741141 and PMID:24174620 copper(0) increases secretion EXP 6480464 ATP7A protein results in increased secretion of Copper CTD PMID:16741141 copper(0) affects transport ISO ATP7A (Homo sapiens) 6480464 ATP7A protein affects the transport of Copper CTD PMID:17109627 copper(0) affects binding ISO ATP7A (Homo sapiens) 6480464 ATP7A protein binds to Copper and Copper binds to ATP7A protein CTD PMID:16873374 and PMID:22577880 copper(0) multiple interactions ISO ATP7A (Homo sapiens) 6480464 [ATP7A protein affects the oxidation of SCO1 protein] which affects the abundance of Copper more ... CTD PMID:10841766 more ... copper(II) chloride increases transport ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in increased transport of cupric chloride CTD PMID:17009961 copper(II) chloride multiple interactions ISO Atp7a (Mus musculus) 6480464 Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein] CTD PMID:25337692 copper(II) chloride affects localization ISO Atp7a (Mus musculus) 6480464 cupric chloride affects the localization of ATP7A protein CTD PMID:16317117 and PMID:25337692 copper(II) chloride decreases glutathionylation ISO ATP7A (Homo sapiens) 6480464 cupric chloride results in decreased glutathionylation of ATP7A protein CTD PMID:20566629 copper(II) chloride multiple interactions ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in decreased susceptibility to [cupric chloride results in increased abundance of Copper] more ... CTD PMID:11092760 more ... copper(II) chloride increases expression EXP 6480464 cupric chloride results in increased expression of ATP7A protein CTD PMID:23174565 copper(II) chloride multiple interactions EXP 6480464 cupric chloride inhibits the reaction [Cycloheximide results in decreased expression of ATP7A protein] more ... CTD PMID:23174565 copper(II) sulfate increases expression ISO ATP7A (Homo sapiens) 6480464 Copper Sulfate results in increased expression of ATP7A protein CTD PMID:24815816 CU-O LINKAGE increases expression ISO ATP7A (Homo sapiens) 6480464 cupric oxide analog results in increased expression of ATP7A mRNA and cupric oxide analog results in increased expression of ATP7A protein CTD PMID:24815816 cycloheximide decreases expression EXP 6480464 Cycloheximide results in decreased expression of ATP7A protein CTD PMID:23174565 cycloheximide multiple interactions EXP 6480464 cupric chloride inhibits the reaction [Cycloheximide results in decreased expression of ATP7A protein] CTD PMID:23174565 cyclosporin A decreases expression ISO Atp7a (Mus musculus) 6480464 Cyclosporine results in decreased expression of ATP7A mRNA CTD PMID:19770486 cyclosporin A decreases expression ISO ATP7A (Homo sapiens) 6480464 Cyclosporine results in decreased expression of ATP7A mRNA CTD PMID:25562108 D-penicillamine multiple interactions ISO ATP7A (Homo sapiens) 6480464 [Penicillamine co-treated with bathocuproine sulfonate] promotes the reaction [CLU protein binds to ATP7A protein] CTD PMID:21242307 decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of ATP7A mRNA CTD PMID:23914054 desferrioxamine B increases expression EXP 6480464 Deferoxamine results in increased expression of ATP7A mRNA CTD PMID:23174565 desferrioxamine B multiple interactions EXP 6480464 cupric chloride promotes the reaction [Deferoxamine results in increased expression of ATP7A mRNA] and Deferoxamine promotes the reaction [cupric chloride results in increased expression of ATP7A protein] CTD PMID:23174565 dextran sulfate multiple interactions ISO Atp7a (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP7A mRNA CTD PMID:29950665 diarsenic trioxide decreases expression ISO Atp7a (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of ATP7A mRNA CTD PMID:35676786 dibutyl phthalate increases expression ISO Atp7a (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of ATP7A mRNA CTD PMID:21266533 dioxygen increases expression ISO Atp7a (Mus musculus) 6480464 Oxygen deficiency results in increased expression of ATP7A mRNA and Oxygen deficiency results in increased expression of ATP7A protein CTD PMID:19351718 and PMID:24614111 dioxygen increases expression ISO ATP7A (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of ATP7A mRNA CTD PMID:24614111 dioxygen affects localization ISO Atp7a (Mus musculus) 6480464 Oxygen deficiency affects the localization of ATP7A protein CTD PMID:19351718 dioxygen multiple interactions ISO Atp7a (Mus musculus) 6480464 tetrathiomolybdate inhibits the reaction [Oxygen deficiency affects the localization of ATP7A protein] CTD PMID:19351718 dorsomorphin multiple interactions ISO ATP7A (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ATP7A mRNA CTD PMID:27188386 doxorubicin affects localization ISO ATP7A (Homo sapiens) 6480464 ATP7A protein affects the localization of Doxorubicin CTD PMID:17510416 doxorubicin decreases response to substance ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in decreased susceptibility to Doxorubicin CTD PMID:17510416 doxorubicin multiple interactions ISO ATP7A (Homo sapiens) 6480464 Brefeldin A inhibits the reaction [ATP7A protein affects the localization of Doxorubicin] and Monensin inhibits the reaction [ATP7A protein affects the localization of Doxorubicin] CTD PMID:17510416 doxorubicin increases export ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in increased export of Doxorubicin CTD PMID:17510416 entinostat decreases expression ISO ATP7A (Homo sapiens) 6480464 entinostat results in decreased expression of ATP7A mRNA CTD PMID:26272509 entinostat multiple interactions ISO ATP7A (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ATP7A mRNA CTD PMID:27188386 ethyl methanesulfonate increases expression ISO ATP7A (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of ATP7A mRNA CTD PMID:23649840 etoposide decreases response to substance ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in decreased susceptibility to Etoposide CTD PMID:17510416 folic acid multiple interactions ISO Atp7a (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP7A mRNA CTD PMID:22206623 FR900359 affects phosphorylation ISO ATP7A (Homo sapiens) 6480464 FR900359 affects the phosphorylation of ATP7A protein CTD PMID:37730182 hexadecanoic acid increases phosphorylation ISO ATP7A (Homo sapiens) 6480464 Palmitic Acid results in increased phosphorylation of ATP7A protein CTD PMID:28073184 hydrogen peroxide multiple interactions ISO ATP7A (Homo sapiens) 6480464 ATP7A protein promotes the reaction [Paraquat results in increased chemical synthesis of Hydrogen Peroxide] and Hydrogen Peroxide promotes the reaction [CLU protein binds to ATP7A protein] CTD PMID:21242307 and PMID:29058724 irinotecan decreases response to substance ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in decreased susceptibility to Irinotecan CTD PMID:17510416 irinotecan increases export ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in increased export of Irinotecan CTD PMID:17510416 iron atom increases expression EXP 6480464 Iron deficiency results in increased expression of ATP7A more ... CTD PMID:16629162 more ... iron atom affects metabolic processing ISO Atp7a (Mus musculus) 6480464 ATP7A protein mutant form affects the metabolism of Iron CTD PMID:25247420 iron atom increases expression ISO Atp7a (Mus musculus) 6480464 Iron deficiency results in increased expression of ATP7A mRNA CTD PMID:23776592 and PMID:24089420 iron atom increases response to substance ISO Atp7a (Mus musculus) 6480464 ATP7A gene mutant form results in increased susceptibility to Iron deficiency CTD PMID:23776592 iron atom affects transport EXP 6480464 ATP7A mutant form affects the transport of Iron CTD PMID:24174620 iron atom multiple interactions EXP 6480464 [Iron deficiency results in increased expression of ATP7A] which results in increased abundance of Copper CTD PMID:24174620 iron atom decreases oxidation ISO Atp7a (Mus musculus) 6480464 ATP7A gene mutant form results in decreased oxidation of Iron CTD PMID:23776592 iron atom multiple interactions ISO Atp7a (Mus musculus) 6480464 [ATP7A gene mutant form co-treated with Iron deficiency] results in increased uptake of Copper more ... CTD PMID:23776592 iron(0) increases expression EXP 6480464 Iron deficiency results in increased expression of ATP7A more ... CTD PMID:16629162 more ... iron(0) affects metabolic processing ISO Atp7a (Mus musculus) 6480464 ATP7A protein mutant form affects the metabolism of Iron CTD PMID:25247420 iron(0) multiple interactions ISO Atp7a (Mus musculus) 6480464 [ATP7A gene mutant form co-treated with Iron deficiency] results in increased uptake of Copper more ... CTD PMID:23776592 iron(0) affects transport EXP 6480464 ATP7A mutant form affects the transport of Iron CTD PMID:24174620 iron(0) decreases oxidation ISO Atp7a (Mus musculus) 6480464 ATP7A gene mutant form results in decreased oxidation of Iron CTD PMID:23776592 iron(0) multiple interactions EXP 6480464 [Iron deficiency results in increased expression of ATP7A] which results in increased abundance of Copper CTD PMID:24174620 iron(0) increases expression ISO Atp7a (Mus musculus) 6480464 Iron deficiency results in increased expression of ATP7A mRNA CTD PMID:23776592 and PMID:24089420 iron(0) increases response to substance ISO Atp7a (Mus musculus) 6480464 ATP7A gene mutant form results in increased susceptibility to Iron deficiency CTD PMID:23776592 ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of ATP7A mRNA CTD PMID:20080153 L-1,4-dithiothreitol multiple interactions ISO ATP7A (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [Ethylmaleimide results in increased glutathionylation of ATP7A protein] CTD PMID:20566629 lead diacetate multiple interactions EXP 6480464 ATP7A protein modified form inhibits the reaction [lead acetate binds to HSPA5 protein] CTD PMID:10702365 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of ATP7A mRNA and lead acetate results in decreased expression of ATP7A protein CTD PMID:24316150 lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of ATP7A mRNA CTD PMID:25579025 lipopolysaccharide increases expression ISO Atp7a (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of ATP7A mRNA CTD PMID:22369063 manganese atom affects localization EXP 6480464 Manganese affects the localization of ATP7A protein CTD PMID:24614235 manganese atom decreases expression EXP 6480464 Manganese results in decreased expression of ATP7A mRNA and Manganese results in decreased expression of ATP7A protein CTD PMID:24614235 manganese(0) affects localization EXP 6480464 Manganese affects the localization of ATP7A protein CTD PMID:24614235 manganese(0) decreases expression EXP 6480464 Manganese results in decreased expression of ATP7A mRNA and Manganese results in decreased expression of ATP7A protein CTD PMID:24614235 manganese(II) chloride affects localization EXP 6480464 manganese chloride affects the localization of ATP7A protein CTD PMID:24614235 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of ATP7A mRNA and manganese chloride results in decreased expression of ATP7A protein CTD PMID:24614235 melanins multiple interactions ISO ATP7A (Homo sapiens) 6480464 [TYR protein co-treated with ATP7A protein] results in increased abundance of Melanins CTD PMID:11092760 methapyrilene affects methylation ISO ATP7A (Homo sapiens) 6480464 Methapyrilene affects the methylation of ATP7A intron CTD PMID:30157460 methimazole increases expression EXP 6480464 Methimazole results in increased expression of ATP7A mRNA CTD PMID:22504374 methyl methanesulfonate increases expression ISO ATP7A (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of ATP7A mRNA CTD PMID:23649840 methylmercury chloride decreases expression ISO ATP7A (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of ATP7A mRNA CTD PMID:28001369 mithramycin multiple interactions EXP 6480464 Plicamycin inhibits the reaction [cobaltous chloride results in increased expression of ATP7A mRNA] CTD PMID:23814049 mithramycin decreases expression EXP 6480464 Plicamycin results in decreased expression of ATP7A mRNA CTD PMID:23814049 mitoxantrone decreases response to substance ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in decreased susceptibility to Mitoxantrone CTD PMID:17510416 monensin A multiple interactions ISO ATP7A (Homo sapiens) 6480464 Monensin inhibits the reaction [ATP7A protein affects the localization of Doxorubicin] CTD PMID:17510416 N-ethylmaleimide increases glutathionylation ISO ATP7A (Homo sapiens) 6480464 Ethylmaleimide results in increased glutathionylation of ATP7A protein CTD PMID:20566629 N-ethylmaleimide multiple interactions ISO ATP7A (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [Ethylmaleimide results in increased glutathionylation of ATP7A protein] CTD PMID:20566629 neocuproine multiple interactions ISO Atp7a (Mus musculus) 6480464 neocuproine inhibits the reaction [ATP7A protein mutant form promotes the reaction [lipopolysaccharide more ... CTD PMID:23604539 nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of ATP7A mRNA and nitrofen results in decreased expression of ATP7A protein CTD PMID:25319798 omeprazole multiple interactions ISO ATP7A (Homo sapiens) 6480464 Omeprazole inhibits the reaction [ATP7A protein results in increased activity of TYR protein] CTD PMID:25337692 omeprazole multiple interactions ISO Atp7a (Mus musculus) 6480464 Omeprazole inhibits the reaction [Copper affects the localization of ATP7A protein] and Omeprazole inhibits the reaction [cupric chloride affects the localization of ATP7A protein] CTD PMID:25337692 oxaliplatin multiple interactions ISO ATP7A (Homo sapiens) 6480464 [MIR495 mRNA results in decreased expression of ATP7A protein] which results in increased susceptibility to oxaliplatin CTD PMID:24038379 oxaliplatin decreases response to substance ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in decreased susceptibility to oxaliplatin CTD PMID:25801007 oxaliplatin affects response to substance ISO ATP7A (Homo sapiens) 6480464 ATP7A protein affects the susceptibility to oxaliplatin CTD PMID:16773204 and PMID:17609664 oxaliplatin increases expression ISO ATP7A (Homo sapiens) 6480464 oxaliplatin results in increased expression of ATP7A mRNA CTD PMID:16773204 paclitaxel decreases response to substance ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in decreased susceptibility to Paclitaxel CTD PMID:17510416 paclitaxel increases expression ISO ATP7A (Homo sapiens) 6480464 Paclitaxel results in increased expression of ATP7A mRNA CTD PMID:20737486 paracetamol affects expression ISO Atp7a (Mus musculus) 6480464 Acetaminophen affects the expression of ATP7A mRNA CTD PMID:17562736 paraquat multiple interactions ISO ATP7A (Homo sapiens) 6480464 ATP7A protein promotes the reaction [Paraquat results in increased chemical synthesis of Hydrogen Peroxide] CTD PMID:29058724 paraquat increases expression ISO ATP7A (Homo sapiens) 6480464 Paraquat results in increased expression of ATP7A mRNA CTD PMID:34097952 paraquat increases response to substance ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in increased susceptibility to Paraquat CTD PMID:29058724 phorbol 13-acetate 12-myristate increases expression ISO ATP7A (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased expression of ATP7A protein CTD PMID:19205902 phorbol 13-acetate 12-myristate multiple interactions ISO ATP7A (Homo sapiens) 6480464 [Tetradecanoylphorbol Acetate results in increased expression of ATP7A protein] which results in increased export of Copper and ATP7A protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FLT1 mRNA] CTD PMID:19205902 pirinixic acid multiple interactions ISO Atp7a (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ATP7A mRNA CTD PMID:19710929 pirinixic acid decreases expression ISO Atp7a (Mus musculus) 6480464 pirinixic acid results in decreased expression of ATP7A mRNA CTD PMID:20813756 platinum increases uptake ISO Atp7a (Mus musculus) 6480464 ATP7A protein results in increased uptake of Platinum CTD PMID:16170571 platinum(0) increases uptake ISO Atp7a (Mus musculus) 6480464 ATP7A protein results in increased uptake of Platinum CTD PMID:16170571 potassium chromate decreases expression ISO ATP7A (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of ATP7A mRNA CTD PMID:22714537 pyrrolidine dithiocarbamate decreases expression ISO ATP7A (Homo sapiens) 6480464 pyrrolidine dithiocarbamic acid results in decreased expression of ATP7A CTD PMID:25070243 quercetin decreases expression ISO ATP7A (Homo sapiens) 6480464 Quercetin results in decreased expression of ATP7A mRNA CTD PMID:21632981 rac-lactic acid decreases expression ISO ATP7A (Homo sapiens) 6480464 Lactic Acid results in decreased expression of ATP7A mRNA CTD PMID:30851411 resveratrol multiple interactions ISO ATP7A (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of ATP7A mRNA CTD PMID:23557933 satraplatin decreases response to substance ISO Atp7a (Mus musculus) 6480464 ATP7A protein results in decreased susceptibility to satraplatin metabolite CTD PMID:16170571 SB 431542 multiple interactions ISO ATP7A (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ATP7A mRNA CTD PMID:27188386 silicon dioxide decreases expression ISO ATP7A (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of ATP7A mRNA CTD PMID:25895662 silver atom affects localization ISO Atp7a (Mus musculus) 6480464 Silver affects the localization of ATP7A protein CTD PMID:16317117 silver atom decreases expression ISO Atp7a (Mus musculus) 6480464 Silver results in decreased expression of ATP7A mRNA CTD PMID:27131904 silver atom affects binding ISO ATP7A (Homo sapiens) 6480464 Silver binds to ATP7A protein CTD PMID:10841766 and PMID:21646353 silver monochloride affects localization ISO Atp7a (Mus musculus) 6480464 silver chloride affects the localization of ATP7A protein CTD PMID:16317117 silver(0) affects localization ISO Atp7a (Mus musculus) 6480464 Silver affects the localization of ATP7A protein CTD PMID:16317117 silver(0) decreases expression ISO Atp7a (Mus musculus) 6480464 Silver results in decreased expression of ATP7A mRNA CTD PMID:27131904 silver(0) affects binding ISO ATP7A (Homo sapiens) 6480464 Silver binds to ATP7A protein CTD PMID:10841766 and PMID:21646353 sodium arsenate increases expression ISO Atp7a (Mus musculus) 6480464 sodium arsenate results in increased expression of ATP7A mRNA CTD PMID:21795629 sodium arsenite decreases expression ISO Atp7a (Mus musculus) 6480464 sodium arsenite results in decreased expression of ATP7A mRNA CTD PMID:37682722 streptozocin multiple interactions ISO Atp7a (Mus musculus) 6480464 ATP7A gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides] more ... CTD PMID:23884884 streptozocin decreases expression ISO Atp7a (Mus musculus) 6480464 Streptozocin results in decreased expression of ATP7A protein CTD PMID:23884884 succimer multiple interactions ISO Atp7a (Mus musculus) 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of ATP7A mRNA CTD PMID:26378955 superoxide increases abundance ISO Atp7a (Mus musculus) 6480464 ATP7A mutant form results in increased abundance of Superoxides CTD PMID:18768397 superoxide multiple interactions ISO Atp7a (Mus musculus) 6480464 [ATP7A protein results in increased activity of SOD3 protein] which results in decreased chemical synthesis of Superoxides more ... CTD PMID:18768397 and PMID:23884884 tetrachloromethane increases expression ISO Atp7a (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of ATP7A mRNA CTD PMID:27339419 tetrathiomolybdate(2-) multiple interactions ISO Atp7a (Mus musculus) 6480464 tetrathiomolybdate inhibits the reaction [Oxygen deficiency affects the localization of ATP7A protein] CTD PMID:19351718 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of ATP7A mRNA CTD PMID:23411599 titanium dioxide decreases expression ISO Atp7a (Mus musculus) 6480464 titanium dioxide results in decreased expression of ATP7A mRNA CTD PMID:29264374 titanium dioxide multiple interactions ISO Atp7a (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP7A mRNA CTD PMID:29950665 trichostatin A increases expression ISO ATP7A (Homo sapiens) 6480464 trichostatin A results in increased expression of ATP7A mRNA CTD PMID:28542535 troglitazone decreases expression ISO Atp7a (Mus musculus) 6480464 troglitazone results in decreased expression of ATP7A mRNA CTD PMID:28973697 tungsten increases expression ISO Atp7a (Mus musculus) 6480464 Tungsten results in increased expression of ATP7A mRNA CTD PMID:30912803 valproic acid increases expression ISO ATP7A (Homo sapiens) 6480464 Valproic Acid results in increased expression of ATP7A mRNA CTD PMID:19101580 and PMID:29154799 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of ATP7A mRNA CTD PMID:29427782 valproic acid decreases expression ISO Atp7a (Mus musculus) 6480464 Valproic Acid results in decreased expression of ATP7A mRNA CTD PMID:20546886 valproic acid increases methylation ISO ATP7A (Homo sapiens) 6480464 Valproic Acid results in increased methylation of ATP7A gene CTD PMID:29154799 vincristine decreases response to substance ISO ATP7A (Homo sapiens) 6480464 ATP7A protein results in decreased susceptibility to Vincristine CTD PMID:17510416
