Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tmem71 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tmem71 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMEM71 mRNA | CTD | PMID:21570461|PMID:26377647 | Tmem71 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TMEM71 mRNA | CTD | PMID:33387578 | Tmem71 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Tmem71 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TMEM71 mRNA | CTD | PMID:19770486|PMID:26290441 | Tmem71 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of TMEM71 mRNA | CTD | PMID:31881176 | Tmem71 | Rat | all-trans-retinoic acid | increases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of TMEM71 mRNA | CTD | PMID:33167477 | Tmem71 | Rat | alpha-Zearalanol | increases expression | EXP | | 6480464 | Zeranol results in increased expression of TMEM71 mRNA | CTD | PMID:35163327 | Tmem71 | Rat | benzo[a]pyrene | decreases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of TMEM71 mRNA | CTD | PMID:20064835 | Tmem71 | Rat | benzo[a]pyrene | affects methylation | ISO | TMEM71 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TMEM71 3' UTR | CTD | PMID:27901495 | Tmem71 | Rat | benzo[a]pyrene | increases methylation | ISO | TMEM71 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TMEM71 promoter | CTD | PMID:27901495 | Tmem71 | Rat | benzo[a]pyrene | increases expression | ISO | Tmem71 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TMEM71 mRNA | CTD | PMID:19770486 | Tmem71 | Rat | benzo[e]pyrene | increases methylation | ISO | TMEM71 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of TMEM71 intron | CTD | PMID:30157460 | Tmem71 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TMEM71 mRNA | CTD | PMID:25181051 | Tmem71 | Rat | bisphenol A | decreases expression | ISO | Tmem71 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TMEM71 mRNA | CTD | PMID:32156529 | Tmem71 | Rat | bisphenol A | decreases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of TMEM71 mRNA | CTD | PMID:29275510 | Tmem71 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TMEM71 mRNA | CTD | PMID:30816183|PMID:31129395|PMID:32528016|PMID:33296240|PMID:34947998 | Tmem71 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with tributyltin] results in increased expression of TMEM71 mRNA | CTD | PMID:31129395 | Tmem71 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of TMEM71 gene | CTD | PMID:28505145 | Tmem71 | Rat | bisphenol F | multiple interactions | ISO | TMEM71 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in decreased methylation of TMEM71 gene | CTD | PMID:31601247 | Tmem71 | Rat | Butylbenzyl phthalate | increases expression | ISO | Tmem71 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased expression of TMEM71 mRNA | CTD | PMID:28392331 | Tmem71 | Rat | cantharidin | decreases expression | ISO | Tmem71 (Mus musculus) | 6480464 | Cantharidin results in decreased expression of TMEM71 mRNA | CTD | PMID:36907384 | Tmem71 | Rat | CGP 52608 | multiple interactions | ISO | TMEM71 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TMEM71 gene] | CTD | PMID:28238834 | Tmem71 | Rat | choline | multiple interactions | ISO | Tmem71 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Tmem71 | Rat | clothianidin | decreases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | clothianidin results in decreased expression of TMEM71 mRNA | CTD | PMID:31626844 | Tmem71 | Rat | crocidolite asbestos | decreases expression | ISO | Tmem71 (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of TMEM71 mRNA | CTD | PMID:29279043 | Tmem71 | Rat | cyclosporin A | increases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TMEM71 mRNA | CTD | PMID:20106945|PMID:25562108 | Tmem71 | Rat | Dibutyl phosphate | affects expression | ISO | TMEM71 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TMEM71 mRNA | CTD | PMID:37042841 | Tmem71 | Rat | dibutyl phthalate | increases expression | ISO | Tmem71 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of TMEM71 mRNA | CTD | PMID:21266533 | Tmem71 | Rat | dimethylarsinic acid | multiple interactions | ISO | Tmem71 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Tmem71 | Rat | diquat | decreases expression | ISO | Tmem71 (Mus musculus) | 6480464 | Diquat results in decreased expression of TMEM71 mRNA | CTD | PMID:36851058 | Tmem71 | Rat | dorsomorphin | multiple interactions | ISO | TMEM71 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Tmem71 | Rat | doxorubicin | decreases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TMEM71 mRNA | CTD | PMID:29803840 | Tmem71 | Rat | doxorubicin | increases expression | ISO | Tmem71 (Mus musculus) | 6480464 | Doxorubicin results in increased expression of TMEM71 mRNA | CTD | PMID:39631538 | Tmem71 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of TMEM71 mRNA | CTD | PMID:29391264 | Tmem71 | Rat | ethanol | decreases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | Ethanol results in decreased expression of TMEM71 mRNA | CTD | PMID:31059573 | Tmem71 | Rat | folic acid | multiple interactions | ISO | Tmem71 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Tmem71 | Rat | folic acid | multiple interactions | ISO | TMEM71 (Homo sapiens) | 6480464 | [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of TMEM71 mRNA | CTD | PMID:24657277 | Tmem71 | Rat | fulvestrant | multiple interactions | ISO | TMEM71 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in decreased methylation of TMEM71 gene | CTD | PMID:31601247 | Tmem71 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TMEM71 mRNA | CTD | PMID:33387578 | Tmem71 | Rat | L-methionine | multiple interactions | ISO | Tmem71 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Tmem71 | Rat | metformin | decreases expression | EXP | | 6480464 | Metformin results in decreased expression of TMEM71 mRNA | CTD | PMID:31324951 | Tmem71 | Rat | methapyrilene | increases methylation | ISO | TMEM71 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of TMEM71 intron | CTD | PMID:30157460 | Tmem71 | Rat | methotrexate | multiple interactions | ISO | TMEM71 (Homo sapiens) | 6480464 | [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of TMEM71 mRNA | CTD | PMID:24657277 | Tmem71 | Rat | methotrexate | decreases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | Methotrexate results in decreased expression of TMEM71 mRNA | CTD | PMID:24657277 | Tmem71 | Rat | methylarsonic acid | multiple interactions | ISO | Tmem71 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Tmem71 | Rat | mono(2-ethylhexyl) phthalate | decreases expression | ISO | Tmem71 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of TMEM71 mRNA | CTD | PMID:22401849 | Tmem71 | Rat | N-nitrosodiethylamine | increases expression | ISO | Tmem71 (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of TMEM71 mRNA | CTD | PMID:24535843 | Tmem71 | Rat | nickel atom | increases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | Nickel results in increased expression of TMEM71 mRNA | CTD | PMID:25583101 | Tmem71 | Rat | okadaic acid | increases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of TMEM71 mRNA | CTD | PMID:38832940 | Tmem71 | Rat | ozone | multiple interactions | ISO | Tmem71 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:34911549 | Tmem71 | Rat | paracetamol | affects expression | ISO | Tmem71 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TMEM71 mRNA | CTD | PMID:17562736 | Tmem71 | Rat | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of TMEM71 mRNA | CTD | PMID:33387578 | Tmem71 | Rat | phenylmercury acetate | multiple interactions | ISO | TMEM71 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Tmem71 | Rat | pirinixic acid | multiple interactions | ISO | Tmem71 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Tmem71 | Rat | SB 431542 | multiple interactions | ISO | TMEM71 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Tmem71 | Rat | sodium arsenate | multiple interactions | ISO | Tmem71 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Tmem71 | Rat | sodium arsenate | increases expression | ISO | Tmem71 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of TMEM71 mRNA | CTD | PMID:39847705 | Tmem71 | Rat | sodium arsenite | affects expression | ISO | TMEM71 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of TMEM71 mRNA | CTD | PMID:29319823 | Tmem71 | Rat | sodium arsenite | multiple interactions | ISO | Tmem71 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Tmem71 | Rat | sodium arsenite | increases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TMEM71 mRNA | CTD | PMID:38568856 | Tmem71 | Rat | sulforaphane | increases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | sulforaphane results in increased expression of TMEM71 mRNA | CTD | PMID:26833863 | Tmem71 | Rat | sunitinib | decreases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of TMEM71 mRNA | CTD | PMID:31533062 | Tmem71 | Rat | tetrachloromethane | increases expression | ISO | Tmem71 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of TMEM71 mRNA | CTD | PMID:27339419 | Tmem71 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TMEM71 mRNA | CTD | PMID:34492290 | Tmem71 | Rat | titanium dioxide | decreases expression | ISO | Tmem71 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of TMEM71 mRNA | CTD | PMID:29264374 | Tmem71 | Rat | tributylstannane | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with tributyltin] results in increased expression of TMEM71 mRNA | CTD | PMID:31129395 | Tmem71 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of TMEM71 mRNA | CTD | PMID:33387578 | Tmem71 | Rat | triclosan | decreases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of TMEM71 mRNA | CTD | PMID:30510588 | Tmem71 | Rat | triphenyl phosphate | affects expression | ISO | TMEM71 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of TMEM71 mRNA | CTD | PMID:37042841 | Tmem71 | Rat | trovafloxacin | decreases expression | ISO | Tmem71 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of TMEM71 mRNA | CTD | PMID:35537566 | Tmem71 | Rat | valproic acid | increases expression | ISO | TMEM71 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TMEM71 mRNA | CTD | PMID:28001369 | Tmem71 | Rat | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of TMEM71 mRNA | CTD | PMID:35594946 | | 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