Bw25 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bw25 (Body weight QTL 25) Rattus norvegicus

Symbol: Bw25
Name: Body weight QTL 25
RGD ID: 1331723
Previously known as: Specialized Center of Research QTL 119; SCOR119
Trait: body mass   (VT:0001259)    
Measurement Type: body weight   (CMO:0000012)    
LOD Score: 3.348
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2793,242,123 - 94,811,326RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.07101,918,330 - 103,867,802RGD_MAPPER_PIPELINERnor6.0
Rnor_5.07102,486,192 - 104,437,717RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4798,568,413 - 100,273,797RGDRGSC3.4
RGSC_v3.1798,602,643 - 100,308,027RGD
Cross Type: Not Available
Strains Crossed: BN/SsNHsd SS/JrHsdMcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
obesity  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement
body weight  (IDA)

Experimental Condition

Measurement Method

Vertebrate Trait
body mass  (IDA)

Rat Strain
BN/SsNHsd  (IEA)
SS/JrHsdMcwi  (IEA)

References

References - curated
# Reference Title Reference Citation
1. A genomic-systems biology map for cardiovascular function. Stoll M, etal., Science 2001 Nov 23;294(5547):1723-6.
Related QTLs

Related QTL Description Reference
Kidm9 maps to same region RGD:70849


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
9295089LOC103692925uncharacterized LOC10369292579303137893285485Rat
40975977LOC120093671uncharacterized LOC12009367179323832593252519Rat
40931067Gcm1-ps1glial cells missing transcription factor 1, pseudogene 179326131793262492Rat
41391831LOC120093673uncharacterized LOC12009367379331604693325937Rat
41336997LOC120094054U6 spliceosomal RNA79336014193360247Rat
7683154LOC102547509uncharacterized LOC10254750979346563393487041Rat
41400961LOC120093860phosphomannomutase 1-like79348989393490745Rat
3130MycMYC proto-oncogene, bHLH transcription factor79359370593598633Rat
6496716Pvt1Pvt1 oncogene79365652893879938Rat
41226657LOC120093674uncharacterized LOC12009367479377016193787074Rat
41375551LOC120094019U6atac minor spliceosomal RNA79424665794246771Rat
41108830LOC120094009small nucleolar RNA SNORA1779445709694457229Rat
40959783LOC120093675uncharacterized LOC12009367579451391194565757Rat
7543030Rgs22lregulator of G-protein signalling 22 like79461920794701950Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10935D7Wox1412779359564793595780Ratregion
10936D7Arb579359562793595833Ratregion
10937D7Wox1515579359562093595781Ratregion
10938D7Wox2913579359563393595754Ratregion
10939D7Mit2720679359563193595843Ratregion
33969D7Mit422379481108594811326Ratregion
36932D7Rat1713579479587794796025Ratregion
35841D7Rat1917679324212393242280Ratregion
39702D7Rat16011979350828593508404Ratregion
7193132MYC29079359646193597750Ratregion
7192489Myc28079359599893596278Ratregion
5031392PMC156147P114379359589493596037Ratregion
5028173D15Mit17079359563293595781Ratregion
5025732RH12944618079359827293598452Ratregion
5053667RH14278113879387820593878343Ratregion
5051895RH9472020079359843893598638Ratregion
5054869RH14347226879366373693664004Ratregion
5078926RH14063218079433522094335400Ratregion
5069222AU0466387879324205193242129Ratregion
5087436PMC165967P540879359619593596603Ratregion
5087434PMC165967P432379359285293593175Ratregion
5087438PMC165967P643079359788793598317Ratregion
5501137PMC148819P429079359764593597935Ratregion
5501149PMC150726P940379359600393596406Ratregion
5501277PMC187450P1079359562993596103Ratregion
5501556G1598712179359590393596024Ratregion
5501710MYC20479359620293596406Ratregion
Position Markers

Flank 1: (D7Rat19)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21016,729,776 - 16,731,416 (+)MAPPER
mRatBN7.2793,242,123 - 93,242,280 (+)MAPPER
Rnor_6.07101,918,330 - 101,918,486NCBI
Rnor_6.01017,019,618 - 17,021,257NCBI
Rnor_5.01016,916,685 - 16,918,324UniSTS
Rnor_5.07102,486,192 - 102,486,348UniSTS
RGSC_v3.4798,568,414 - 98,568,570UniSTS
RGSC_v3.4798,568,413 - 98,568,570RGD
RGSC_v3.41016,992,235 - 16,993,874UniSTS
RGSC_v3.1798,602,643 - 98,602,800RGD
Celera1016,382,362 - 16,384,001UniSTS
SHRSP x BN Map754.56RGD
SHRSP x BN Map754.56UniSTS
Peak: (D7Rat135)
Rat AssemblyChrPosition (strand)Source
mRatBN7.27102,297,359 - 102,297,520 (-)MAPPER
Rnor_6.07111,519,266 - 111,519,426NCBI
Rnor_5.07111,453,751 - 111,453,911UniSTS
RGSC_v3.47108,021,524 - 108,021,684UniSTS
RGSC_v3.47108,021,523 - 108,021,684RGD
RGSC_v3.17108,055,754 - 108,055,914RGD
Celera798,750,661 - 98,750,821UniSTS
RH 3.4 Map7722.5RGD
RH 3.4 Map7722.5UniSTS
RH 2.0 Map11183.0RGD
SHRSP x BN Map757.9199RGD
Flank 2: (D7Mit4)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2794,811,085 - 94,811,326 (+)MAPPER
Rnor_6.07103,815,550 - 103,815,788NCBI
Rnor_6.07103,867,558 - 103,867,802NCBI
Rnor_5.07104,385,465 - 104,385,703UniSTS
Rnor_5.07104,437,473 - 104,437,717UniSTS
RGSC_v3.47100,273,558 - 100,273,797RGD
RGSC_v3.47100,273,559 - 100,273,797UniSTS
RGSC_v3.17100,307,789 - 100,308,027RGD
Celera791,443,180 - 91,443,414UniSTS
RH 3.4 Map7657.0RGD
RH 3.4 Map7657.0UniSTS
RH 2.0 Map7534.0RGD
Cytogenetic Map7 RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
10450828Scl79Serum cholesterol level QTL 793.50.001blood HDL cholesterol amount (VT:0000184)blood low density lipoprotein cholesterol level (CMO:0000053)789867376101773158Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1641908Teswt1Testicular weight QTL 13.28testis mass (VT:1000644)both testes wet weight (CMO:0000175)78022129994811326Rat
1331723Bw25Body weight QTL 253.348body mass (VT:0001259)body weight (CMO:0000012)79324212394811326Rat
724537Niddm52Non-insulin dependent diabetes mellitus QTL 520.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)78022129993595843Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)793595647106839474Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Bw25

RGD Curation Notes
Note Type Note Reference
qtl_general additional information, including phenotype and mapping information, can be found at A genomics-systems biology map for cardiovascular function 70849
qtl_general change in body weight between day of catheter surgery and day of Lasix injection (SCOR119) 70849