S1pr3 (sphingosine-1-phosphate receptor 3) - Rat Genome Database

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Gene: S1pr3 (sphingosine-1-phosphate receptor 3) Rattus norvegicus
Analyze
Symbol: S1pr3
Name: sphingosine-1-phosphate receptor 3
RGD ID: 1583843
Description: Predicted to enable G protein-coupled receptor activity and integrin binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of establishment of endothelial barrier; and regulation of metabolic process. Predicted to act upstream of or within several processes, including Notch signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and regulation of interleukin-1 beta production. Predicted to be active in cytoplasm; plasma membrane; and presynapse. Orthologous to human S1PR3 (sphingosine-1-phosphate receptor 3); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; INTERACTS WITH acetamide; aldehydo-D-glucose; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cardiac sphingosine-1-phosphate specific receptor; Edg3; Edg3l; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3; LOC306792; lpb3; similar to Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3); sphingosine 1-phosphate receptor 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81713,932,773 - 13,946,213 (-)NCBIGRCr8
mRatBN7.21713,781,050 - 13,794,408 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1713,781,050 - 13,794,505 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1713,704,546 - 13,717,841 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01715,315,258 - 15,328,555 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01713,631,365 - 13,644,660 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01713,799,383 - 13,812,877 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1713,799,383 - 13,812,704 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01715,871,251 - 15,884,751 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41719,657,822 - 19,661,106 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1713,529,246 - 13,542,351 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 140 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
S1pr3Rat(1->4)-beta-D-glucan multiple interactionsISOS1pr3 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of S1PR3 mRNACTDPMID:36331819
S1pr3Rat1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expressionISOS1PR3 (Homo sapiens)6480464o and p'-DDT results in increased expression of S1PR3 mRNACTDPMID:19371625
S1pr3Rat1,2-dimethylhydrazine decreases expressionISOS1pr3 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of S1PR3 mRNACTDPMID:22206623
S1pr3Rat1,2-dimethylhydrazine multiple interactionsISOS1pr3 (Mus musculus)6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of S1PR3 mRNA]CTDPMID:22206623
S1pr3Rat17beta-estradiol multiple interactionsISOS1PR3 (Homo sapiens)6480464[Estradiol binds to ESR2 protein] which results in increased expression of S1PR3 mRNACTDPMID:20404318
S1pr3Rat17beta-estradiol decreases expressionISOS1PR3 (Homo sapiens)6480464Estradiol results in decreased expression of S1PR3 mRNACTDPMID:19167446 and PMID:28711546
S1pr3Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOS1pr3 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of S1PR3 mRNACTDPMID:20702594
S1pr3Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOS1pr3 (Mus musculus)6480464[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of S1PR3 mRNACTDPMID:25975270
S1pr3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOS1pr3 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of S1PR3 mRNACTDPMID:21889950
S1pr3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOS1pr3 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of S1PR3 mRNACTDPMID:19933214
S1pr3Rat2,3,7,8-Tetrachlorodibenzofuran affects expressionISOS1pr3 (Mus musculus)64804642 more ...CTDPMID:20702594
S1pr3Rat4,4'-sulfonyldiphenol increases expressionISOS1pr3 (Mus musculus)6480464bisphenol S results in increased expression of S1PR3 mRNACTDPMID:30951980
S1pr3Rat5-aza-2'-deoxycytidine multiple interactionsISOS1PR3 (Homo sapiens)6480464[Decitabine co-treated with trichostatin A] affects the expression of S1PR3 mRNACTDPMID:17189669
S1pr3Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of S1PR3 mRNACTDPMID:31881176
S1pr3Rataflatoxin B1 increases expressionISOS1PR3 (Homo sapiens)6480464Aflatoxin B1 results in increased expression of S1PR3 mRNACTDPMID:22100608
S1pr3RatAflatoxin B2 alpha decreases methylationISOS1PR3 (Homo sapiens)6480464aflatoxin B2 results in decreased methylation of S1PR3 3' UTRCTDPMID:30157460
S1pr3Rataldehydo-D-glucose decreases expressionEXP 6480464Glucose results in decreased expression of S1PR3 mRNACTDPMID:22406263
S1pr3Ratall-trans-retinoic acid decreases expressionISOS1PR3 (Homo sapiens)6480464Tretinoin results in decreased expression of S1PR3 mRNACTDPMID:21934132
S1pr3Ratall-trans-retinoic acid multiple interactionsISOS1pr3 (Mus musculus)6480464[bisphenol F co-treated with Tretinoin] results in decreased expression of S1PR3 mRNACTDPMID:30951980
S1pr3Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of S1PR3 mRNACTDPMID:16483693

1 to 20 of 140 rows

Biological Process
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
S1pr3Ratadenylate cyclase-activating G protein-coupled receptor signaling pathway involved_inIBAMGI:1333809 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
S1pr3Ratadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway acts_upstream_of_or_withinISOS1pr3 (Mus musculus)1624291 PMID:11443127RGDPMID:11443127
S1pr3RatG protein-coupled receptor signaling pathway involved_inIEAARBA:ARBA000290211600115GO_REF:0000117UniProtGO_REF:0000117
S1pr3RatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
S1pr3RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
S1pr3Ratinflammatory response acts_upstream_of_or_withinISOS1pr3 (Mus musculus)1624291MGI:2182637 PMID:18305483RGDPMID:18305483
S1pr3Ratnegative regulation of establishment of endothelial barrier involved_inISOS1PR3 (Homo sapiens)1624291 PMID:24851274RGDPMID:24851274
S1pr3RatNotch signaling pathway acts_upstream_of_or_withinISOS1pr3 (Mus musculus)1624291 PMID:23117660RGDPMID:23117660
S1pr3Ratregulation of interleukin-1 beta production acts_upstream_of_or_withinISOS1pr3 (Mus musculus)1624291MGI:2182637 PMID:18305483RGDPMID:18305483
S1pr3Ratregulation of metabolic process involved_inIBAMGI:101908 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
S1pr3Ratsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043
S1pr3Ratsphingosine-1-phosphate receptor signaling pathway involved_inIEAGO:00380361600115GO_REF:0000108GOCGO_REF:0000108
1 to 12 of 12 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
S1pr3Ratcytoplasm is_active_inIBAMGI:104615 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
S1pr3Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
S1pr3Ratmembrane located_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
S1pr3Ratplasma membrane located_inISOS1PR3 (Homo sapiens)1624291 PMID:24851274RGDPMID:24851274
S1pr3Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
S1pr3Ratplasma membrane is_active_inIBAMGI:104615 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
S1pr3Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
S1pr3Ratpresynapse is_active_inISOS1pr3 (Mus musculus)1624291 PMID:35781853RGDPMID:35781853

Molecular Function

  

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
S1pr3Ratsphingosine 1-phosphate signaling pathway  ISOS1PR3 (Homo sapiens)6484113 PIDPID:200046
S1pr3Ratsphingosine 1-phosphate signaling pathway  ISOS1PR3 (Homo sapiens)6484113 PIDPID:200123

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:10220556   PMID:10915638   PMID:11443127   PMID:18305483   PMID:18535287   PMID:21887342   PMID:22828274   PMID:23117660   PMID:24851274   PMID:25869501   PMID:28634078   PMID:29266713  
PMID:29536648  



S1pr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81713,932,773 - 13,946,213 (-)NCBIGRCr8
mRatBN7.21713,781,050 - 13,794,408 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1713,781,050 - 13,794,505 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1713,704,546 - 13,717,841 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01715,315,258 - 15,328,555 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01713,631,365 - 13,644,660 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01713,799,383 - 13,812,877 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1713,799,383 - 13,812,704 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01715,871,251 - 15,884,751 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41719,657,822 - 19,661,106 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1713,529,246 - 13,542,351 (-)NCBICelera
Cytogenetic Map17p14NCBI
S1PR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38988,990,863 - 89,005,155 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl988,990,863 - 89,005,155 (+)EnsemblGRCh38hg38GRCh38
GRCh37991,605,778 - 91,620,070 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36990,796,182 - 90,809,745 (+)NCBINCBI36Build 36hg18NCBI36
Build 34988,835,915 - 88,849,478NCBI
Celera962,189,011 - 62,202,574 (+)NCBICelera
Cytogenetic Map9q22.1NCBI
HuRef961,438,768 - 61,452,511 (+)NCBIHuRef
CHM1_1991,754,483 - 91,768,224 (+)NCBICHM1_1
T2T-CHM13v2.09101,153,351 - 101,167,644 (+)NCBIT2T-CHM13v2.0
S1pr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391351,562,654 - 51,576,833 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1351,562,675 - 51,576,833 (+)EnsemblGRCm39 Ensembl
GRCm381351,408,618 - 51,422,797 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1351,408,639 - 51,422,797 (+)EnsemblGRCm38mm10GRCm38
MGSCv371351,503,987 - 51,518,166 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361351,421,260 - 51,435,293 (+)NCBIMGSCv36mm8
Celera1352,481,303 - 52,495,482 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1326.12NCBI
S1pr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555153,024,258 - 3,035,996 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555153,024,258 - 3,035,996 (-)NCBIChiLan1.0ChiLan1.0
S1PR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21150,455,855 - 50,460,900 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1950,459,337 - 50,463,288 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0960,080,189 - 60,094,311 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1988,126,416 - 88,140,149 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl988,126,476 - 88,137,333 (+)Ensemblpanpan1.1panPan2
S1PR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1197,102,708 - 97,107,611 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl197,104,652 - 97,105,857 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha197,565,504 - 97,576,501 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0197,714,499 - 97,725,495 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl197,714,526 - 97,725,557 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1197,342,250 - 97,353,244 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0197,061,323 - 97,072,318 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0197,819,845 - 97,830,838 (-)NCBIUU_Cfam_GSD_1.0
S1pr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494410,793,383 - 10,849,904 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493764539,701 - 42,497 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493764539,690 - 40,790 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
S1PR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14659,309 - 671,706 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114659,314 - 674,969 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214880,158 - 898,709 (+)NCBISscrofa10.2Sscrofa10.2susScr3
S1PR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11299,484,615 - 99,498,211 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1299,494,423 - 99,495,559 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603887,806,079 - 87,819,666 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
S1pr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476523,659,973 - 23,673,809 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476523,660,155 - 23,673,855 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in S1pr3
105 total Variants

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:37
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000019473
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 31 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat

1 to 10 of 31 rows
RH132124  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21713,781,313 - 13,781,506 (+)MAPPERmRatBN7.2
Rnor_6.01713,799,647 - 13,799,839NCBIRnor6.0
Rnor_5.01715,871,515 - 15,871,707UniSTSRnor5.0
RGSC_v3.41719,658,086 - 19,658,278UniSTSRGSC3.4
Celera1713,529,510 - 13,529,702UniSTS
RH 3.4 Map17145.5UniSTS
Cytogenetic Map17p14UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000019473   ⟹   ENSRNOP00000019473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1713,781,050 - 13,794,505 (-)Ensembl
Rnor_6.0 Ensembl1713,799,383 - 13,812,615 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085581   ⟹   ENSRNOP00000074813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1713,799,384 - 13,812,704 (-)Ensembl
RefSeq Acc Id: NM_001271143   ⟹   NP_001258072
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81713,932,773 - 13,946,013 (-)NCBI
mRatBN7.21713,781,050 - 13,794,296 (-)NCBI
Rnor_6.01713,799,383 - 13,812,615 (-)NCBI
Rnor_5.01715,871,251 - 15,884,751 (-)NCBI
Celera1713,529,246 - 13,542,351 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006253680   ⟹   XP_006253742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81713,932,773 - 13,946,141 (-)NCBI
mRatBN7.21713,781,050 - 13,794,408 (-)NCBI
Rnor_6.01713,799,383 - 13,812,746 (-)NCBI
Rnor_5.01715,871,251 - 15,884,751 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063276353   ⟹   XP_063132423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81713,932,773 - 13,946,213 (-)NCBI
Protein RefSeqs NP_001258072 (Get FASTA)   NCBI Sequence Viewer  
  XP_006253742 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132423 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD56238 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019473.1
  ENSRNOP00000104368
RefSeq Acc Id: NP_001258072   ⟸   NM_001271143
- UniProtKB: F1M9D3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253742   ⟸   XM_006253680
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K910 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074813   ⟸   ENSRNOT00000085581
Ensembl Acc Id: ENSRNOP00000019473   ⟸   ENSRNOT00000019473
RefSeq Acc Id: XP_063132423   ⟸   XM_063276353
- Peptide Label: isoform X1
- UniProtKB: F1M9D3 (UniProtKB/TrEMBL)
Name Modeler Protein Id AA Range Protein Structure
AF-F1M9D3-F1-model_v2 AlphaFold F1M9D3 1-379 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700340
Promoter ID:EPDNEW_R10863
Type:multiple initiation site
Name:S1pr3_1
Description:sphingosine-1-phosphate receptor 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01713,812,628 - 13,812,688EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-10069 BioCyc
Ensembl Genes ENSRNOG00000014524 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019473.4 UniProtKB/TrEMBL
  ENSRNOT00000131320 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  EDG3_rcpt UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  S1P_rcpt UniProtKB/TrEMBL
KEGG Report rno:306792 UniProtKB/TrEMBL
NCBI Gene 306792 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PhenoGen S1pr3 PhenoGen
PRINTS EDG3RECEPTOR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
  S1PRECEPTOR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014524 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0G2K910 ENTREZGENE
  F1M9D3 ENTREZGENE, UniProtKB/TrEMBL
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-05-20 S1pr3  sphingosine-1-phosphate receptor 3  Edg3  endothelial differentiation, sphingolipid G-protein-coupled receptor, 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-12 Edg3  endothelial differentiation, sphingolipid G-protein-coupled receptor, 3  LOC306792  similar to Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC306792  similar to Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3)      Symbol and Name status set to provisional 70820 PROVISIONAL