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Gene: S1pr3 (sphingosine-1-phosphate receptor 3) Rattus norvegicus

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Symbol:

S1pr3

Name:

sphingosine-1-phosphate receptor 3

RGD ID:

1583843

Description:

Predicted to enable G protein-coupled receptor activity and integrin binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and negative regulation of establishment of endothelial barrier. Predicted to act upstream of or within several processes, including Notch signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and regulation of interleukin-1 beta production. Predicted to be located in membrane. Predicted to be active in cytoplasm; plasma membrane; and presynapse. Orthologous to human S1PR3 (sphingosine-1-phosphate receptor 3); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; INTERACTS WITH acetamide; aldehydo-D-glucose; ammonium chloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cardiac sphingosine-1-phosphate specific receptor; Edg3; Edg3l; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3; LOC306792; lpb3; similar to Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3); sphingosine 1-phosphate receptor 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	13,932,773 - 13,946,213 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	13,928,444 - 13,947,197 (-)	Ensembl				GRCr8
mRatBN7.2	17	13,781,050 - 13,794,408 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	13,781,050 - 13,794,505 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	13,704,546 - 13,717,841 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	15,315,258 - 15,328,555 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	13,631,365 - 13,644,660 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	13,799,383 - 13,812,877 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	13,799,383 - 13,812,704 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	15,871,251 - 15,884,751 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	19,657,822 - 19,661,106 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	13,529,246 - 13,542,351 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

aldehydo-D-glucose (EXP)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

apigenin (EXP)

aristolochic acid A (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bleomycin A2 (ISO)

buta-1,3-diene (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

carmustine (ISO)

chloroprene (ISO)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

copper(II) chloride (ISO)

coumestrol (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

D-glucose (EXP)

daidzein (ISO)

daidzein 7-O-beta-D-glucoside (ISO)

DDE (ISO)

dexamethasone (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP,ISO)

diethylstilbestrol (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (EXP,ISO)

Enterolactone (ISO)

entinostat (ISO)

enzalutamide (ISO)

ethanol (ISO)

fingolimod hydrochloride (ISO)

folic acid (ISO)

fulvestrant (ISO)

genistein (ISO)

genistein 7-O-beta-D-glucoside (ISO)

glucose (EXP)

glycitein (ISO)

glycitin (ISO)

L-methionine (ISO)

lipopolysaccharide (EXP,ISO)

methylisothiazolinone (ISO)

methylmercury chloride (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (ISO)

N-Nitrosopyrrolidine (ISO)

nickel atom (ISO)

nickel sulfate (ISO)

nitrofen (EXP)

okadaic acid (ISO)

oxaliplatin (EXP)

ozone (ISO)

panobinostat (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

potassium dichromate (ISO)

propionic acid (ISO)

resveratrol (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

simvastatin (ISO)

sodium arsenite (ISO)

Soman (EXP)

sphingosine 1-phosphate (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

torcetrapib (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

troglitazone (ISO)

urethane (ISO)

valproic acid (EXP,ISO)

vanadyl sulfate (ISO)

WIN 55212-2 (ISO)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-activating G protein-coupled receptor signaling pathway (IBA)

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ISO)

G protein-coupled receptor signaling pathway (IEA)

inflammatory response (ISO)

negative regulation of establishment of endothelial barrier (ISO)

Notch signaling pathway (ISO)

regulation of interleukin-1 beta production (ISO)

signal transduction (IEA)

sphingosine-1-phosphate receptor signaling pathway (IEA)

Cellular Component

cytoplasm (IBA)

membrane (IEA)

plasma membrane (IBA,IEA,ISO)

presynapse (ISO)

Molecular Function

G protein-coupled receptor activity (IBA,IEA)

integrin binding (ISO)

protein binding (ISO)

sphingosine-1-phosphate receptor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

sphingosine 1-phosphate signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10220556	PMID:10915638	PMID:11443127	PMID:18305483	PMID:18535287	PMID:21887342	PMID:22828274	PMID:23117660	PMID:24851274	PMID:25869501	PMID:28634078	PMID:29266713
PMID:29536648

Genomics

Comparative Map Data

S1pr3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	13,932,773 - 13,946,213 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	13,928,444 - 13,947,197 (-)	Ensembl				GRCr8
mRatBN7.2	17	13,781,050 - 13,794,408 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	13,781,050 - 13,794,505 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	13,704,546 - 13,717,841 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	15,315,258 - 15,328,555 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	13,631,365 - 13,644,660 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	13,799,383 - 13,812,877 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	13,799,383 - 13,812,704 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	15,871,251 - 15,884,751 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	17	19,657,822 - 19,661,106 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	17	13,529,246 - 13,542,351 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

S1PR3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	88,990,863 - 89,005,155 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	88,990,863 - 89,005,155 (+)	Ensembl			hg38	GRCh38
GRCh37	9	91,605,778 - 91,620,070 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	90,796,182 - 90,809,745 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	88,835,915 - 88,849,478	NCBI
Celera	9	62,189,011 - 62,202,574 (+)	NCBI		Celera
Cytogenetic Map	9	q22.1	NCBI
HuRef	9	61,438,768 - 61,452,511 (+)	NCBI		HuRef
CHM1_1	9	91,754,483 - 91,768,224 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	101,153,351 - 101,167,644 (+)	NCBI		T2T-CHM13v2.0

S1pr3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	51,562,654 - 51,576,833 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	51,562,675 - 51,576,833 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	13	51,408,618 - 51,422,797 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	51,408,639 - 51,422,797 (+)	Ensembl			mm10	GRCm38
MGSCv37	13	51,503,987 - 51,518,166 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	13	51,421,260 - 51,435,293 (+)	NCBI		MGSCv36	mm8
Celera	13	52,481,303 - 52,495,482 (+)	NCBI		Celera
Cytogenetic Map	13	A5	NCBI
cM Map	13	26.12	NCBI

S1pr3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955515	3,024,258 - 3,035,996 (-)	Ensembl
ChiLan1.0	NW_004955515	3,024,258 - 3,035,996 (-)	NCBI	ChiLan1.0	ChiLan1.0

S1PR3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	50,455,855 - 50,460,900 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	50,459,337 - 50,463,288 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	60,080,189 - 60,094,311 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	88,126,416 - 88,140,149 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	88,126,476 - 88,137,333 (+)	Ensembl			panPan2	panpan1.1

S1PR3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	97,102,708 - 97,107,611 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	97,104,652 - 97,105,857 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	97,565,504 - 97,576,501 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	97,714,499 - 97,725,495 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	97,714,526 - 97,725,557 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	97,342,250 - 97,353,244 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	97,061,323 - 97,072,318 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	97,819,845 - 97,830,838 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

S1pr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	10,793,383 - 10,849,904 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004937645	39,701 - 42,497 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004937645	39,690 - 40,790 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

S1PR3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	659,309 - 671,706 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	659,314 - 674,969 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	880,158 - 898,709 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

S1PR3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	99,484,615 - 99,498,211 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	99,494,423 - 99,495,559 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	87,806,079 - 87,819,666 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

S1pr3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624765	23,659,973 - 23,673,809 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624765	23,660,155 - 23,673,855 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

S1pr3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	14	69,795,980 - 69,809,233 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in S1pr3
138 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	40
Count of miRNA genes:	37
Interacting mature miRNAs:	38
Transcripts:	ENSRNOT00000019473
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354581	Bp247	Blood pressure QTL 247	4.5		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	17	1	43999106	Rat
2300002	Iddm36	Insulin dependent diabetes mellitus QTL 36	1.98		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	17	9266755	40968173	Rat
2293664	Bmd28	Bone mineral density QTL 28	5.1	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	17	4360057	27233623	Rat
8552966	Pigfal18	Plasma insulin-like growth factor 1 level QTL 18	8.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	17	12860942	57860942	Rat
1300123	Bp194	Blood pressure QTL 194	2.82		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	2120843	42054133	Rat
1582224	Epfw4	Epididymal fat weight QTL 4	3.5	0.0058	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	17	9206505	23859062	Rat
1582225	Bw67	Body weight QTL 67	6.2	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
2302377	Scl61	Serum cholesterol level QTL 61	4.36		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	17	6221998	58177198	Rat
1582226	Bw64	Body weight QTL 64	4.2	0.0017	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
9589151	Insul30	Insulin level QTL 30	8.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	17	12860942	57860942	Rat
10401807	Kidm52	Kidney mass QTL 52			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	1	31706603	Rat
10054088	Scort28	Serum corticosterone level QTL 28	2.04	0.0102	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	4733534	49733534	Rat
9589057	Scfw6	Subcutaneous fat weight QTL 6	8.62	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	17	12860942	57860942	Rat
1582208	Kidm32	Kidney mass QTL 32	3.9	0.0018	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	9206505	23859062	Rat
9590154	Scort9	Serum corticosterone level QTL 9	23.57	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	12860942	57860942	Rat
9590088	Insglur7	Insulin/glucose ratio QTL 7	20.38	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	17	12860942	57860942	Rat
1549900	Iddm20	Insulin dependent diabetes mellitus QTL 20	3.7		pancreas integrity trait (VT:0010560)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	17	1	22181410	Rat
2317053	Aia25	Adjuvant induced arthritis QTL 25	2.69		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	17	10604694	55604694	Rat
1354613	Kidm14	Kidney mass QTL 14	6.2		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	17	1	36045694	Rat
7411666	Foco31	Food consumption QTL 31	11.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	17	12860942	57860942	Rat
2324619	Coatc4	Coat color QTL 4		0.001	coat/hair pigmentation trait (VT:0010463)	pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)	17	1	21499218	Rat
2303627	Vencon8	Ventilatory control QTL 8		0.001	respiration trait (VT:0001943)	tidal volume (CMO:0000222)	17	4733534	49733534	Rat
1581553	Pur14	Proteinuria QTL 14	5.3	0.0001	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	17	7985243	16523460	Rat
70184	BpQTLcluster14	Blood pressure QTL cluster 14	3.38		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	8574342	32199534	Rat
1582258	Bw76	Body weight QTL 76	4.6	0.0005	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
631207	Niddm41	Non-insulin dependent diabetes mellitus QTL 41			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	17	1	38037084	Rat
1582199	Insul5	Insulin level QTL 5	3.4	0.0119	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	17	9206505	23859062	Rat
1354662	Rf49	Renal function QTL 49	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	17	1	43999106	Rat
2293648	Bmd31	Bone mineral density QTL 31	4.5	0.0001	femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	17	4360057	27233623	Rat
1354658	Spl8	Serum phospholipid level QTL 8	3.8		blood VLDL phospholipid amount (VT:0010507)	blood very low density lipoprotein phospholipid level (CMO:0001571)	17	1	43999106	Rat
1641902	Colcr7	Colorectal carcinoma resistance QTL 7	3.35	0.0044	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	17	2120843	22087569	Rat
1582241	Bw70	Body weight QTL 70	4.6	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
1582245	Bw73	Body weight QTL 73	4.6	0.0004	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
9590316	Scort21	Serum corticosterone level QTL 21	4.75	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	1	22877318	Rat

Markers in Region

RH132124

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	13,781,313 - 13,781,506 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	13,799,647 - 13,799,839	NCBI	Rnor6.0
Rnor_5.0	17	15,871,515 - 15,871,707	UniSTS	Rnor5.0
RGSC_v3.4	17	19,658,086 - 19,658,278	UniSTS	RGSC3.4
Celera	17	13,529,510 - 13,529,702	UniSTS
RH 3.4 Map	17	145.5	UniSTS
Cytogenetic Map	17	p14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	64	59	6	323	164	11	140	76	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001271143	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006253679	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006253680	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063276353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF184914	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FN805905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000019473 ⟹ ENSRNOP00000019473

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	13,932,612 - 13,947,197 (-)	Ensembl
mRatBN7.2 Ensembl	17	13,781,050 - 13,794,505 (-)	Ensembl
Rnor_6.0 Ensembl	17	13,799,383 - 13,812,615 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000085581 ⟹ ENSRNOP00000074813

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	17	13,799,384 - 13,812,704 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000131320 ⟹ ENSRNOP00000104368

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	13,928,444 - 13,946,382 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000153183 ⟹ ENSRNOP00000106963

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	13,929,165 - 13,946,382 (-)	Ensembl

RefSeq Acc Id:

NM_001271143 ⟹ NP_001258072

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	13,932,773 - 13,946,013 (-)	NCBI
mRatBN7.2	17	13,781,050 - 13,794,296 (-)	NCBI
Rnor_6.0	17	13,799,383 - 13,812,615 (-)	NCBI
Rnor_5.0	17	15,871,251 - 15,884,751 (-)	NCBI
Celera	17	13,529,246 - 13,542,351 (-)	NCBI

Sequence:

show sequence

GCAAGTTCAGGGGCAGGCGACAAGGTCCGGGTGCTGAGCGAGGCGGCTGGACAAGCTTAGCCAG
AGAGAAACCTGAGGCCACGAGCGACCTCCGGAGGAGCCCCTAAACTGGAGCCTTAGCTGAGACT
TAGCGGTGGCAGCATGCAACCAGCCCAGATGAGCCTTGCAGAACGAGAGCCTGTTTCCAACACT
CTTGCTGCAGTCAGGCCTGCTGCACGCCTTCAGGAACCCACCACCGCTGTCCCAATTGTCCCCT
GAAATGAACGTTCCTGGCGCGCCCTCTCGTGGACTGTTGAGGTAACCATCCGTCTATAGGAAGT
CATGGCATCCACGCATGCGCAGGGCCACCCGCCAGTCTTGGGGAATGATACTCTCCGGGAACAT
TATGATTACGTGGGGAAGCTGGCAGGCAGGCTGCGGGACCCCCCTGAGGGTAGCACCCTCATCA
CCACCATCCTCTTCTTGGTCACCTGTAGCTTCATCGTCTTGGAGAACCTGATGGTTTTGATTGC
CATCTGGAAAAACAATAAATTTCATAACCGCATGTACTTTTTCATCGGCAACTTGGCTCTCTGC
GACCTGCTGGCCGGCATAGCCTACAAGGTCAACATTCTGATGTCCGGTAGGAAGACGTTCAGCC
TGTCTCCAACAGTGTGGTTCCTCAGGGAGGGCAGTATGTTCGTAGCCCTGGGCGCATCCACATG
CAGCTTATTGGCCATTGCCATTGAGCGGCACCTGACCATGATCAAGATGAGGCCGTACGACGCC
AACAAGAAGCACCGCGTGTTCCTTCTGATTGGGATGTGCTGGCTAATTGCCTTCTCGCTGGGTG
CCCTGCCCATCCTGGGCTGGAACTGCCTGGAGAACTTTCCCGACTGCTCTACCATCTTGCCCCT
CTACTCCAAGAAATACATTGCCTTTCTCATCAGCATCTTCACAGCCATTCTGGTGACCATCGTC
ATCTTGTACGCGCGCATCTACTTCCTGGTCAAGTCCAGCAGCCGCAGGGTGGCCAACCACAACT
CCGAGAGATCCATGGCCCTTCTGCGGACCGTAGTGATCGTGGTGAGCGTGTTCATCGCCTGTTG
GTCCCCCCTTTTCATCCTCTTCCTCATCGATGTGGCCTGCAGGGCGAAGGAGTGCTCCATCCTC
TTCAAGAGTCAGTGGTTCATCATGCTGGCTGTCCTCAACTCGGCCATGAACCCTGTCATCTACA
CGCTGGCCAGCAAAGAGATGCGGCGTGCTTTCTTCCGGTTGGTGTGCGGCTGTCTGGTCAAGGG
CAAGGGGACCCAGGCCTCCCCGATGCAGCCTGCTCTTGACCCGAGCAGAAGTAAATCAAGCTCC
AGTAACAACAGCAGCAGCCACTCTCCAAAGGTCAAGGAAGACCTGCCCCATGTGGCTACCTCTT
CCTGCGTCACTGACAAAACGAGGTCGCTTCAGAATGGGGTCCTCTGCAAGTGAATGTCTCCACA
GGTCAAGCTCTGCAGCCACACCTATTTATTGCACGCATTCGCTTCCACGCGAGGCCTTAGAGAT
CTTGACCCTGGAGGTCTGCTTGACGTGGCCACCAACTCCTGAGGAGGAGACCCAAGGAGACACC
GATACATTTCAGCCCGGACATGGATGTGCCTTATGGGTTGCAGGCTCCATCCTTCTGAATGTAC
CAAGCTGCTGACGTTGTCCACTCCCTTTGGATGCCGATTTCCCCGGTCCAGGGAGGGCAGGTAG
TGATGTGCTATGCACATGCGCTTTGGGATGGAATCTTCCTATCTTCACACTACATTAATTTTCA
TAGAATGGGTGCTCCTGTATGTGTCTGTCCGTTGCTGTGTTGTACAGAATGTGTATGCCAGGTT
TTCCCAGGTGGAGCCCATTACAAAGTGTTGGTCCCCCCACATCTTGTGTAACGGTTGGTCCGAA
CCTGCAGGCACAGCTGTACCGGATTCAGCATGTGATAAGGTGGTGCGCCTTTCCCGGTGCCCTT
GTGCCGGTGTCCTAGCTCATGGCTGTGAAAAGTTACTCAAGTATTCCTTATTCTCAAAAAGCCT
CACCCAAGAGCAGCCCAGGTGTGTGGGTCTCACCTTTACATACCCGTGTCCCTCCCTCTTGGGT
CCCTTCCATAAGCTTAAGTACATCTGAAAGCCAGATTATGTGATCGTTGAGGCATTTCTGAAAA
TCACTGAAAAGCCAGCCAGGATCTCTCAAAATGCTGGCATCACTGAAGGAAGAGCCCATGAGGA
GAGGCAAGGTGCTCTCCACCGTGGGTCACCCTTCCAGGGGACGGCAGTCTGCTGCATGTAGAGA
GTTTCCAGCAGTGACATTCACAAGCCAGCCCTTCAACTGTATGGTACTGAGTTCAGTTCCATGT
AGAGAAGCTTGATTCGTGTGTAGAGAAGCTTGATGCCAGTCAGCTTTGCCGCCACCTTTTGCTG
GCAAGGAGCTGAAGCTGTCAGCAAAGCTTCTCGTCTCCCTCAATTGTGGACCCTGACCAGGACC
CTTCAGTGAGAGGAATCCGCCAGGCTAGGAGGCGTGATGTGGTTCTTTGCACCCTCTTCAGAGA
GAACCATTCCCATGCCCATATGATGGGCGCTCCACCGCTTGGACCTGCGTTCCTTTGTCCATCC
TGTAAGGAAAACGCTTAGAAGACACCTCTGAAATCCCCTCCCCAAGGACTCTGCCCGCGGGACA
CACAGGTGGGTATGTTGGAGAGAGCAGCCAGCACCCATGCTCCCAGAACAGTCTTTGGAAGGAC
TCACACTCGGGGAAACTTCATGTCAGAGCTCCCCATAAGTTGATTAGCATCAGAGACACACCTA
CCAACCTTTTTAAAGATGATTTTTCTCTCAATGGTTACTTGATGGCATTTGCTCTTGCTTAGGG
ACACTTTTCCTGGGCCCTAGGTAACCATGGACTGACTAACGAAAGACTTCCCCTGGTGGATATA
GGTCACTGCCAGGGAATTCTGCTGGATCATTGGCCTATCTGTCTCTTCTCTACGTCACCGAGAA
AATAACTTATTCTCTCATCATGGTGTTGACAAAAAACCCAGGCATTTCTGGGAAAGGAAAGCAT
GCAAGTGCTGGGCTGAGGGAAAATAACAGGCCAGTGTGTGGGGGAGTTGAGGTGGAAAATGAAT
GGGGCTTGAGGACGTGCTCTTCCCTAATCGGAATGCTTCGAGGCCATGGATCTGGGTCACTAAT
ATTAATAACACATTGTACATGACTCTGACTTCTCTATATCCTCCTGTGTCTGCTTTCATTCAAC
AGCCCTTGCAGAGGGCCACACCTACCATCCCCAGCTAGGAGGTGACATTTGTAGAATGACAGAG
TGTCGAGCAGTTGAAATTAGAAATACACTAAGACCTAATTGCACTCACTTGATGTATGCCAAAT
GGAGCAATCATCCGTGACGCCAGTGTGCGCTCCTTTCCCTAGCTAAGCCACCGAGACAGCATTG
AGACCGAGTGCACCCAAACCCTCACCCCGAAGGTCGGAAACAAGAGAAGCCAGAGACCCTGGGG
CCTGCCCCAGGTAGCGAGTGACCTTTACTACTTGCAGTTTATGTTTGTTAATAATAAATAAAAC
CAAAAGCCTTTATATAAACCCA

hide sequence

RefSeq Acc Id:

XM_006253680 ⟹ XP_006253742

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	13,932,773 - 13,946,141 (-)	NCBI
mRatBN7.2	17	13,781,050 - 13,794,408 (-)	NCBI
Rnor_6.0	17	13,799,383 - 13,812,746 (-)	NCBI
Rnor_5.0	17	15,871,251 - 15,884,751 (-)	NCBI

Sequence:

show sequence

AAATGGGAACCAGCCCGCAGAAGCTCTGAAGCTTGGGTTAGGGGCGGCAGGAGGCGGGTGACTC
TGGGCCCCGCCCCGGAGGGCTGTGGCAAAAGTTTGCCTTCGGATCCTCTGGGGCAGAATCTGGG
CGAGCAAGTTCAGGGGCAGGCGACAAGGTCCGGGTGCTGAGCGAGGCGGCTGGACAAGCTTAGC
CAGAGAGAAACCTGAGGCCACGAGCGACCTCCGGAGGAGCCCCTAAACTGGAGCCTTAGCTGAG
ACTTAGCGGTGGCAGCATGCAACCAGCCCAGATGAGCCTTGCAGAACGAGAGCCTGTTTCCAAC
ACTCTTGCTGCAGTCAGGCCTGCTGCACGCCTTCAGGAACCCACCACCGCTGTCCCAATTGTCC
CCTGAAATGAACGTTCCTGGCGCGCCCTCTCGTGGACTGTTGAGCTTCATCGTCTTGGAGAACC
TGATGGTTTTGATTGCCATCTGGAAAAACAATAAATTTCATAACCGCATGTACTTTTTCATCGG
CAACTTGGCTCTCTGCGACCTGCTGGCCGGCATAGCCTACAAGGTCAACATTCTGATGTCCGGT
AGGAAGACGTTCAGCCTGTCTCCAACAGTGTGGTTCCTCAGGGAGGGCAGTATGTTCGTAGCCC
TGGGCGCATCCACATGCAGCTTATTGGCCATTGCCATTGAGCGGCACCTGACCATGATCAAGAT
GAGGCCGTACGACGCCAACAAGAAGCACCGCGTGTTCCTTCTGATTGGGATGTGCTGGCTAATT
GCCTTCTCGCTGGGTGCCCTGCCCATCCTGGGCTGGAACTGCCTGGAGAACTTTCCCGACTGCT
CTACCATCTTGCCCCTCTACTCCAAGAAATACATTGCCTTTCTCATCAGCATCTTCACAGCCAT
TCTGGTGACCATCGTCATCTTGTACGCGCGCATCTACTTCCTGGTCAAGTCCAGCAGCCGCAGG
GTGGCCAACCACAACTCCGAGAGATCCATGGCCCTTCTGCGGACCGTAGTGATCGTGGTGAGCG
TGTTCATCGCCTGTTGGTCCCCCCTTTTCATCCTCTTCCTCATCGATGTGGCCTGCAGGGCGAA
GGAGTGCTCCATCCTCTTCAAGAGTCAGTGGTTCATCATGCTGGCTGTCCTCAACTCGGCCATG
AACCCTGTCATCTACACGCTGGCCAGCAAAGAGATGCGGCGTGCTTTCTTCCGGTTGGTGTGCG
GCTGTCTGGTCAAGGGCAAGGGGACCCAGGCCTCCCCGATGCAGCCTGCTCTTGACCCGAGCAG
AAGTAAATCAAGCTCCAGTAACAACAGCAGCAGCCACTCTCCAAAGGTCAAGGAAGACCTGCCC
CATGTGGCTACCTCTTCCTGCGTCACTGACAAAACGAGGTCGCTTCAGAATGGGGTCCTCTGCA
AGTGAATGTCTCCACAGGTCAAGCTCTGCAGCCACACCTATTTATTGCACGCATTCGCTTCCAC
GCGAGGCCTTAGAGATCTTGACCCTGGAGGTCTGCTTGACGTGGCCACCAACTCCTGAGGAGGA
GACCCAAGGAGACACCGATACATTTCAGCCCGGACATGGATGTGCCTTATGGGTTGCAGGCTCC
ATCCTTCTGAATGTACCAAGCTGCTGACGTTGTCCACTCCCTTTGGATGCCGATTTCCCCGGTC
CAGGGAGGGCAGGTAGTGATGTGCTATGCACATGCGCTTTGGGATGGAATCTTCCTATCTTCAC
ACTACATTAATTTTCATAGAATGGGTGCTCCTGTATGTGTCTGTCCGTTGCTGTGTTGTACAGA
ATGTGTATGCCAGGTTTTCCCAGGTGGAGCCCATTACAAAGTGTTGGTCCCCCCACATCTTGTG
TAACGGTTGGTCCGAACCTGCAGGCACAGCTGTACCGGATTCAGCATGTGATAAGGTGGTGCGC
CTTTCCCGGTGCCCTTGTGCCGGTGTCCTAGCTCATGGCTGTGAAAAGTTACTCAAGTATTCCT
TATTCTCAAAAAGCCTCACCCAAGAGCAGCCCAGGTGTGTGGGTCTCACCTTTACATACCCGTG
TCCCTCCCTCTTGGGTCCCTTCCATAAGCTTAAGTACATCTGAAAGCCAGATTATGTGATCGTT
GAGGCATTTCTGAAAATCACTGAAAAGCCAGCCAGGATCTCTCAAAATGCTGGCATCACTGAAG
GAAGAGCCCATGAGGAGAGGCAAGGTGCTCTCCACCGTGGGTCACCCTTCCAGGGGACGGCAGT
CTGCTGCATGTAGAGAGTTTCCAGCAGTGACATTCACAAGCCAGCCCTTCAACTGTATGGTACT
GAGTTCAGTTCCATGTAGAGAAGCTTGATTCGTGTGTAGAGAAGCTTGATGCCAGTCAGCTTTG
CCGCCACCTTTTGCTGGCAAGGAGCTGAAGCTGTCAGCAAAGCTTCTCGTCTCCCTCAATTGTG
GACCCTGACCAGGACCCTTCAGTGAGAGGAATCCGCCAGGCTAGGAGGCGTGATGTGGTTCTTT
GCACCCTCTTCAGAGAGAACCATTCCCATGCCCATATGATGGGCGCTCCACCGCTTGGACCTGC
GTTCCTTTGTCCATCCTGTAAGGAAAACGCTTAGAAGACACCTCTGAAATCCCCTCCCCAAGGA
CTCTGCCCGCGGGACACACAGGTGGGTATGTTGGAGAGAGCAGCCAGCACCCATGCTCCCAGAA
CAGTCTTTGGAAGGACTCACACTCGGGGAAACTTCATGTCAGAGCTCCCCATAAGTTGATTAGC
ATCAGAGACACACCTACCAACCTTTTTAAAGATGATTTTTCTCTCAATGGTTACTTGATGGCAT
TTGCTCTTGCTTAGGGACACTTTTCCTGGGCCCTAGGTAACCATGGACTGACTAACGAAAGACT
TCCCCTGGTGGATATAGGTCACTGCCAGGGAATTCTGCTGGATCATTGGCCTATCTGTCTCTTC
TCTACGTCACCGAGAAAATAACTTATTCTCTCATCATGGTGTTGACAAAAAACCCAGGCATTTC
TGGGAAAGGAAAGCATGCAAGTGCTGGGCTGAGGGAAAATAACAGGCCAGTGTGTGGGGGAGTT
GAGGTGGAAAATGAATGGGGCTTGAGGACGTGCTCTTCCCTAATCGGAATGCTTCGAGGCCATG
GATCTGGGTCACTAATATTAATAACACATTGTACATGACTCTGACTTCTCTATATCCTCCTGTG
TCTGCTTTCATTCAACAGCCCTTGCAGAGGGCCACACCTACCATCCCCAGCTAGGAGGTGACAT
TTGTAGAATGACAGAGTGTCGAGCAGTTGAAATTAGAAATACACTAAGACCTAATTGCACTCAC
TTGATGTATGCCAAATGGAGCAATCATCCGTGACGCCAGTGTGCGCTCCTTTCCCTAGCTAAGC
CACCGAGACAGCATTGAGACCGAGTGCACCCAAACCCTCACCCCGAAGGTCGGAAACAAGAGAA
GCCAGAGACCCTGGGGCCTGCCCCAGGTAGCGAGTGACCTTTACTACTTGCAGTTTATGTTTGT
TAATAATAAATAAAACCAAAAGCCTTTATATAAACCCA

hide sequence

RefSeq Acc Id:

XM_063276353 ⟹ XP_063132423

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	13,932,773 - 13,946,213 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001258072	(Get FASTA)	NCBI Sequence Viewer
	XP_006253742	(Get FASTA)	NCBI Sequence Viewer
	XP_063132423	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD56238	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000019473.1
	ENSRNOP00000104368
	ENSRNOP00000104368.1
	ENSRNOP00000106963.1

RefSeq Acc Id:

NP_001258072 ⟸ NM_001271143

- UniProtKB:

F1M9D3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASTHAQGHPPVLGNDTLREHYDYVGKLAGRLRDPPEGSTLITTILFLVTCSFIVLENLMVLIA
IWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGRKTFSLSPTVWFLREGSMFVALGASTC
SLLAIAIERHLTMIKMRPYDANKKHRVFLLIGMCWLIAFSLGALPILGWNCLENFPDCSTILPL
YSKKYIAFLISIFTAILVTIVILYARIYFLVKSSSRRVANHNSERSMALLRTVVIVVSVFIACW
SPLFILFLIDVACRAKECSILFKSQWFIMLAVLNSAMNPVIYTLASKEMRRAFFRLVCGCLVKG
KGTQASPMQPALDPSRSKSSSSNNSSSHSPKVKEDLPHVATSSCVTDKTRSLQNGVLCK

hide sequence

RefSeq Acc Id:	XP_006253742 ⟸ XM_006253680
- Peptide Label:	isoform X2
- UniProtKB:	A0A0G2K910 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNVPGAPSRGLLSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGRK TFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKKHRVFLLIGMCWLIAF SLGALPILGWNCLENFPDCSTILPLYSKKYIAFLISIFTAILVTIVILYARIYFLVKSSSRRVA NHNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRAKECSILFKSQWFIMLAVLNSAMNP VIYTLASKEMRRAFFRLVCGCLVKGKGTQASPMQPALDPSRSKSSSSNNSSSHSPKVKEDLPHV ATSSCVTDKTRSLQNGVLCK hide sequence

Ensembl Acc Id:

ENSRNOP00000074813 ⟸ ENSRNOT00000085581

Ensembl Acc Id:

ENSRNOP00000019473 ⟸ ENSRNOT00000019473

RefSeq Acc Id:	XP_063132423 ⟸ XM_063276353
- Peptide Label:	isoform X1
- UniProtKB:	F1M9D3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000104368 ⟸ ENSRNOT00000131320

Ensembl Acc Id:

ENSRNOP00000106963 ⟸ ENSRNOT00000153183

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M9D3-F1-model_v2	AlphaFold	F1M9D3	1-379	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700340

Promoter ID:

EPDNEW_R10863

Type:

multiple initiation site

Name:

S1pr3_1

Description:

sphingosine-1-phosphate receptor 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	13,812,628 - 13,812,688	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1583843	AgrOrtholog
BioCyc Gene	G2FUF-10069	BioCyc
Ensembl Genes	ENSRNOG00000014524	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000019473.5	UniProtKB/TrEMBL
	ENSRNOT00000131320	ENTREZGENE
	ENSRNOT00000131320.1	UniProtKB/TrEMBL
	ENSRNOT00000153183.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	7TM_GPCR_Rhodpsn	UniProtKB/TrEMBL
	EDG3_rcpt	UniProtKB/TrEMBL
	GPCR_Rhodpsn_supfam	UniProtKB/TrEMBL
	S1P_rcpt	UniProtKB/TrEMBL
KEGG Report	rno:306792	UniProtKB/TrEMBL
NCBI Gene	306792	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PhenoGen	S1pr3	PhenoGen
PRINTS	EDG3RECEPTOR	UniProtKB/TrEMBL
	GPCRRHODOPSN	UniProtKB/TrEMBL
	S1PRECEPTOR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000014524	RatGTEx
SMART	7TM_GPCR_Srsx	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A0G2K910	ENTREZGENE
	F1M9D3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-05-20	S1pr3	sphingosine-1-phosphate receptor 3	Edg3	endothelial differentiation, sphingolipid G-protein-coupled receptor, 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-12	Edg3	endothelial differentiation, sphingolipid G-protein-coupled receptor, 3	LOC306792	similar to Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-19	LOC306792	similar to Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - PID (archival)