Gene:	Vav3 ( Rattus norvegicus ) vav 3 guanine nucleotide exchange factor
Synonyms:	LOC295378; RGD1565941; vav 3 oncogene; similar to Vav 3 oncogene; RGD1565941_predicted; similar to Vav 3 oncogene (predicted);
ArrayIDs:	6172428; 6284083; 6516912; 6211398; 6446298; 5774463; 1393605_at; 5667192; 5851910; 6405278; 5854433; 6180436; 5848720; 6546722; 6252679; 6113059; 6690374; 6541709; 6488141; 6627368; 6524148; 6362900; 5670487; 5891664; 6050844; 6537938; 5891614; 6528391; 6140148; 5647346; 5768204; 6425763;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: VAV3     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Vav3     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Vav3 Rat Celera Assembly 2 189650166 - 189990562     RGSC genome assembly v3.4 2 204981583 - 205326505     Cytogenetic 2 q34-q41 Mus musculus Vav3 Mouse genome assembly build 36.1 3 109143601 - 109488612     Cytogenetic 3 3 G1 Homo sapiens VAV3 human genome assembly 1 107825831 - 108219580     Human genome assembly build 36.2 1 107915310 - 108309061     Cytogenetic 1 p13.3   View comparative maps:      NCBI MapViewer
Genome
View:
Annotation
Molecular Function	Gene Ontology Rac guanyl-nucleotide exchange factor activity,  protein binding,  Rho guanyl-nucleotide exchange factor activity ...  (details...)
Biological Process	Gene Ontology integrin-mediated signaling pathway,  cell projection assembly,  small GTPase mediated signal transduction ...  (details...)
Cellular Component	Gene Ontology intracellular,  cytoplasm,  plasma membrane ...  (details...)
External Links
Databases	DATABASE ID SOURCE SMART: CH IPI SMART: PH IPI SMART: RhoGEF IPI SMART: SH2 IPI SMART: SH3 IPI SMART: C1 IPI PROSITE: DH_2 IPI PROSITE: CH IPI PROSITE: DH_1 IPI PROSITE: ZF_DAG_PE_2 IPI PROSITE: ZF_DAG_PE_1 IPI PROSITE: SH3 IPI PROSITE: SH2 IPI PROSITE: PH_DOMAIN IPI UNIPARC: UPI0000251047 IPI UNIPARC: UPI0000DA2154 IPI UNIPARC: UPI0001B7BC2A IPI KEGG Report: rno:295378 ENTREZGENE HomoloGene Group ID: 38143 ENTREZGENE Pfam: SH3_2 IPI Pfam: C1_1 IPI Pfam: CH IPI Pfam: PH IPI Pfam: RhoGEF IPI Pfam: SH2 IPI Pfam: SH3_1 IPI KEGG Pathway: 04666 ENTREZGENE KEGG Pathway: 04662 ENTREZGENE KEGG Pathway: 04062 ENTREZGENE KEGG Pathway: 04664 ENTREZGENE KEGG Pathway: 04660 ENTREZGENE KEGG Pathway: 04810 ENTREZGENE KEGG Pathway: 04650 ENTREZGENE KEGG Pathway: 04670 ENTREZGENE KEGG Pathway: 04510 ENTREZGENE InterPro: DH-domain. IPI InterPro: Calponin-homology. IPI InterPro: Calponin_act_bd. IPI InterPro: SM22_calponin. IPI InterPro: GDS_CDC24_CS. IPI InterPro: Pleckstrin_homology. IPI InterPro: SH3_region. IPI InterPro: SH3_domain. IPI InterPro: SH3_2. IPI InterPro: SH2. IPI InterPro: Prot_Kinase_C-like_PE/DAG_bd. IPI IPI: IPI00369128 IPI IPI: IPI00762958 IPI IPI: IPI00950062 IPI Ensembl Protein: ENSRNOP00000060088 IPI Ensembl Protein: ENSRNOP00000027813 IPI Gene3D-CATH: SH2 IPI Gene3D-CATH: Calponin-homology IPI Gene3D-CATH: RhoGEF IPI Entrez Gene: Vav3 ENTREZGENE Ensembl Genes: ENSRNOG00000020485 IPI Superfamily-SCOP: Calponin-homology IPI Superfamily-SCOP: DH-domain IPI Superfamily-SCOP: SH3 IPI PRINTS: SH3DOMAIN. IPI PRINTS: SM22CALPONIN. IPI PRINTS: SH2DOMAIN. IPI
Sequences	Nucleotide: AAHX01019479 Get FASTA Search GEO Profiles Nucleotide: AAHX01019478 Get FASTA Search GEO Profiles Nucleotide: AAHX01019472 Get FASTA Search GEO Profiles Nucleotide: AAHX01019477 Get FASTA Search GEO Profiles Nucleotide: AAHX01019476 Get FASTA Search GEO Profiles Nucleotide: AAHX01019475 Get FASTA Search GEO Profiles Nucleotide: AAHX01019474 Get FASTA Search GEO Profiles Nucleotide: AAHX01019473 Get FASTA Search GEO Profiles Nucleotide: AABR03016289 Get FASTA Search GEO Profiles Nucleotide: AAHX01019481 Get FASTA Search GEO Profiles Nucleotide: AABR03015033 Get FASTA Search GEO Profiles Nucleotide: AABR03014231 Get FASTA Search GEO Profiles Nucleotide: AABR03013239 Get FASTA Search GEO Profiles Nucleotide: AABR03012969 Get FASTA Search GEO Profiles Nucleotide: AABR03012848 Get FASTA Search GEO Profiles Nucleotide: AABR03012235 Get FASTA Search GEO Profiles Nucleotide: XM_227600 Get FASTA Search GEO Profiles Nucleotide: XM_001072341 Get FASTA Search GEO Profiles Nucleotide: AAHX01019480 Get FASTA Search GEO Profiles Nucleotide: AABR03015417 Get FASTA Search GEO Profiles (View all 20 Nucleotide Accessions) Protein: XP_227600 Get FASTA Protein: XP_001072341 Get FASTA (View all 2 Protein Accessions)
Clusters	UniGene: 27881
References
Curated References	1 references in RGD related to Vav3
Database Information
RGD ID	1565941
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 23-OCT-08: Vav3 vav 3 guanine nucleotide exchange factor Vav3 vav 3 oncogene APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863 07-MAR-08: Vav3 vav 3 oncogene RGD1565941_predicted similar to Vav 3 oncogene (predicted) APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863 07-MAR-06: RGD1565941_predicted similar to Vav 3 oncogene (predicted) LOC295378 similar to Vav 3 oncogene APPROVED Symbol and Name status set to approved 1299863 09-FEB-06: LOC295378 similar to Vav 3 oncogene PROVISIONAL Symbol and Name status set to provisional 70820