VAV3 (vav guanine nucleotide exchange factor 3) - Rat Genome Database

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Gene: VAV3 (vav guanine nucleotide exchange factor 3) Homo sapiens
Analyze
Symbol: VAV3
Name: vav guanine nucleotide exchange factor 3
RGD ID: 1343957
HGNC Page HGNC:12659
Description: Enables guanyl-nucleotide exchange factor activity. Involved in several processes, including B cell receptor signaling pathway; positive regulation of B cell proliferation; and regulation of cell size. Part of immunological synapse.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: FLJ40431; guanine nucleotide exchange factor VAV3; vav 3 guanine nucleotide exchange factor; vav 3 oncogene; VAV-3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381107,571,161 - 107,965,180 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1107,571,161 - 107,965,180 (-)EnsemblGRCh38hg38GRCh38
GRCh371108,113,783 - 108,507,802 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361107,915,305 - 108,309,068 (-)NCBINCBI36Build 36hg18NCBI36
Build 341107,825,831 - 108,219,580NCBI
Celera1106,288,518 - 106,682,258 (-)NCBICelera
Cytogenetic Map1p13.3NCBI
HuRef1106,059,691 - 106,453,322 (-)NCBIHuRef
CHM1_11108,228,649 - 108,622,362 (-)NCBICHM1_1
T2T-CHM13v2.01107,608,692 - 108,002,653 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP)
amphotericin B  (EXP)
antimycin A  (EXP)
antirheumatic drug  (EXP)
aristolochic acid A  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzo[b]fluoranthene  (ISO)
Benzo[k]fluoranthene  (EXP)
bisphenol A  (EXP,ISO)
butanal  (EXP)
calcitriol  (EXP)
carbon nanotube  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (EXP)
cordycepin  (EXP)
crocidolite asbestos  (EXP)
cyclosporin A  (EXP)
dextran sulfate  (ISO)
diarsenic trioxide  (EXP)
dioxygen  (EXP)
diuron  (ISO)
dorsomorphin  (EXP)
fipronil  (ISO)
genistein  (EXP)
glycidol  (ISO)
glyphosate  (ISO)
Indeno[1,2,3-cd]pyrene  (EXP)
leflunomide  (EXP)
luteolin  (EXP)
methotrexate  (EXP,ISO)
methylmercury chloride  (EXP)
methylmercury(1+)  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (EXP)
ochratoxin A  (EXP)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paracetamol  (ISO)
phenylmercury acetate  (EXP)
pirinixic acid  (ISO)
resveratrol  (EXP)
SB 431542  (EXP)
silicon dioxide  (EXP)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
succimer  (EXP)
tamibarotene  (EXP)
temozolomide  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetraphene  (EXP)
thioacetamide  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
tributylstannane  (EXP)
Tributyltin oxide  (EXP)
trichostatin A  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
urethane  (EXP)
valproic acid  (EXP)
vinclozolin  (ISO)
vorinostat  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)
cytosol  (IEA,TAS)
immunological synapse  (IDA)
plasma membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Autism  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8622875   PMID:8990121   PMID:9269777   PMID:9705494   PMID:10523675   PMID:10713454   PMID:10938113   PMID:11094073   PMID:11756498   PMID:11805146   PMID:12376548   PMID:12400014  
PMID:12477932   PMID:12577067   PMID:12787561   PMID:14702039   PMID:14757747   PMID:15456756   PMID:15708849   PMID:16273093   PMID:16384856   PMID:16762975   PMID:16982329   PMID:17875758  
PMID:18079321   PMID:18518979   PMID:18654987   PMID:19008376   PMID:19429868   PMID:19546854   PMID:19911011   PMID:19913121   PMID:20126983   PMID:20140222   PMID:20379614   PMID:20463313  
PMID:20628086   PMID:20936779   PMID:21455584   PMID:21706016   PMID:21765461   PMID:21822214   PMID:21873635   PMID:22416266   PMID:22467863   PMID:22493691   PMID:22544459   PMID:22659453  
PMID:22973453   PMID:23023561   PMID:23033535   PMID:23033540   PMID:23281476   PMID:23376485   PMID:23402756   PMID:23403204   PMID:23566222   PMID:23648065   PMID:24072493   PMID:24388013  
PMID:24722205   PMID:24728074   PMID:24797263   PMID:24886537   PMID:25305756   PMID:25430880   PMID:25715123   PMID:25754235   PMID:25791293   PMID:25964534   PMID:26337083   PMID:26695150  
PMID:27143812   PMID:27172236   PMID:27453460   PMID:27507811   PMID:27930970   PMID:28157227   PMID:28285969   PMID:28513273   PMID:28811363   PMID:28927664   PMID:29194596   PMID:29858212  
PMID:30083818   PMID:31959200   PMID:32203420   PMID:32296183   PMID:32540412   PMID:32561640   PMID:32640241   PMID:34292486   PMID:35563538   PMID:35650206   PMID:36215168   PMID:36602863  
PMID:36736316   PMID:36960857   PMID:37085264   PMID:37092056   PMID:37467637   PMID:37783052  


Genomics

Comparative Map Data
VAV3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381107,571,161 - 107,965,180 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1107,571,161 - 107,965,180 (-)EnsemblGRCh38hg38GRCh38
GRCh371108,113,783 - 108,507,802 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361107,915,305 - 108,309,068 (-)NCBINCBI36Build 36hg18NCBI36
Build 341107,825,831 - 108,219,580NCBI
Celera1106,288,518 - 106,682,258 (-)NCBICelera
Cytogenetic Map1p13.3NCBI
HuRef1106,059,691 - 106,453,322 (-)NCBIHuRef
CHM1_11108,228,649 - 108,622,362 (-)NCBICHM1_1
T2T-CHM13v2.01107,608,692 - 108,002,653 (-)NCBIT2T-CHM13v2.0
Vav3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393109,247,757 - 109,593,010 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3109,247,969 - 109,593,014 (+)EnsemblGRCm39 Ensembl
GRCm383109,340,465 - 109,685,694 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3109,340,653 - 109,685,698 (+)EnsemblGRCm38mm10GRCm38
MGSCv373109,143,601 - 109,488,612 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363109,468,739 - 109,813,750 (+)NCBIMGSCv36mm8
Celera3111,676,271 - 112,018,586 (+)NCBICelera
Cytogenetic Map3F3NCBI
cM Map348.13NCBI
Vav3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82199,699,861 - 200,042,344 (+)NCBIGRCr8
mRatBN7.22197,011,901 - 197,354,321 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2197,011,831 - 197,354,321 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2204,649,909 - 204,985,041 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02202,536,978 - 202,872,292 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02197,354,079 - 197,689,388 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02212,247,061 - 212,585,818 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2212,247,451 - 212,585,818 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02231,716,228 - 232,053,965 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42204,982,222 - 205,326,505 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2189,650,820 - 189,990,562 (+)NCBICelera
Cytogenetic Map2q41NCBI
Vav3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543511,326,910 - 11,599,043 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543511,326,910 - 11,599,043 (-)NCBIChiLan1.0ChiLan1.0
VAV3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21119,178,596 - 119,579,566 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11118,341,662 - 118,742,435 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01110,101,651 - 110,531,294 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11109,216,867 - 109,617,658 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1109,210,813 - 109,617,658 (-)Ensemblpanpan1.1panPan2
VAV3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1643,663,787 - 44,002,362 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl643,559,985 - 44,000,811 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha646,430,623 - 46,782,296 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0643,923,858 - 44,276,352 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl643,923,610 - 44,276,343 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1643,658,033 - 44,009,951 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0643,628,551 - 43,981,239 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0644,059,178 - 44,411,293 (+)NCBIUU_Cfam_GSD_1.0
Vav3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058116,810,838 - 117,160,637 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936731417,322 - 767,429 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936731417,610 - 767,427 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VAV3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4111,824,896 - 112,202,825 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14111,825,071 - 112,202,833 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24122,945,014 - 122,967,699 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VAV3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12025,631,104 - 26,023,854 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2025,631,171 - 26,023,849 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603832,217,599 - 32,613,494 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vav3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247723,604,165 - 4,022,990 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247723,604,553 - 4,022,986 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in VAV3
69 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1p21.3-13.3(chr1:98557000-107949047)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053878]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053878]|See cases [RCV000053878] Chr1:98557000..107949047 [GRCh38]
Chr1:99022556..108491669 [GRCh37]
Chr1:98795144..108293192 [NCBI36]
Chr1:1p21.3-13.3		 pathogenic
GRCh38/hg38 1p21.2-13.2(chr1:101618097-111703028)x1 copy number loss See cases [RCV000053879] Chr1:101618097..111703028 [GRCh38]
Chr1:102083653..112245650 [GRCh37]
Chr1:101856241..112047173 [NCBI36]
Chr1:1p21.2-13.2		 pathogenic
GRCh38/hg38 1p21.1-13.3(chr1:106074587-110144290)x1 copy number loss See cases [RCV000053881] Chr1:106074587..110144290 [GRCh38]
Chr1:106617209..110686912 [GRCh37]
Chr1:106418732..110488435 [NCBI36]
Chr1:1p21.1-13.3		 pathogenic
GRCh38/hg38 1p21.3-13.3(chr1:97410602-110670510)x1 copy number loss See cases [RCV000053877] Chr1:97410602..110670510 [GRCh38]
Chr1:97876158..111213132 [GRCh37]
Chr1:97648746..111014655 [NCBI36]
Chr1:1p21.3-13.3		 pathogenic
GRCh37/hg19 1p13.3(chr1:107538505-108235719)x3 copy number gain See cases [RCV000234919] Chr1:107538505..108235719 [GRCh37]
Chr1:1p13.3		 uncertain significance
GRCh38/hg38 1p13.3(chr1:107456821-108010045)x3 copy number gain See cases [RCV000133828] Chr1:107456821..108010045 [GRCh38]
Chr1:107999443..108552667 [GRCh37]
Chr1:107800966..108354190 [NCBI36]
Chr1:1p13.3		 uncertain significance
GRCh38/hg38 1p13.3(chr1:107395369-108383738)x3 copy number gain See cases [RCV000134068] Chr1:107395369..108383738 [GRCh38]
Chr1:107937991..108926360 [GRCh37]
Chr1:107739514..108727883 [NCBI36]
Chr1:1p13.3		 uncertain significance
GRCh38/hg38 1p21.3-13.3(chr1:97272349-108893138)x1 copy number loss See cases [RCV000135333] Chr1:97272349..108893138 [GRCh38]
Chr1:97737905..109435760 [GRCh37]
Chr1:97510493..109237283 [NCBI36]
Chr1:1p21.3-13.3		 pathogenic
GRCh38/hg38 1p21.1-12(chr1:104325484-119977655)x3 copy number gain See cases [RCV000142953] Chr1:104325484..119977655 [GRCh38]
Chr1:104868106..120471049 [GRCh37]
Chr1:104669629..120321801 [NCBI36]
Chr1:1p21.1-12		 pathogenic
GRCh38/hg38 1p21.1-13.2(chr1:105468292-112190626)x1 copy number loss See cases [RCV000142760] Chr1:105468292..112190626 [GRCh38]
Chr1:106010914..112733248 [GRCh37]
Chr1:105812437..112534771 [NCBI36]
Chr1:1p21.1-13.2		 pathogenic
GRCh37/hg19 1p13.3(chr1:108115974-108313305)x3 copy number gain Breast ductal adenocarcinoma [RCV000207026] Chr1:108115974..108313305 [GRCh37]
Chr1:1p13.3		 uncertain significance
GRCh37/hg19 1p36.12-12(chr1:20608823-120546301)x3 copy number loss not provided [RCV000762767] Chr1:20608823..120546301 [GRCh37]
Chr1:1p36.12-12		 likely benign
NM_006113.5(VAV3):c.2062A>C (p.Asn688His) single nucleotide variant not specified [RCV004281850] Chr1:107603117 [GRCh38]
Chr1:108145739 [GRCh37]
Chr1:1p13.3		 uncertain significance
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
NM_006113.5(VAV3):c.1135C>G (p.Arg379Gly) single nucleotide variant not specified [RCV004327492] Chr1:107755465 [GRCh38]
Chr1:108298087 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.117T>A (p.Asp39Glu) single nucleotide variant not specified [RCV004310915] Chr1:107964753 [GRCh38]
Chr1:108507375 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.2416G>C (p.Glu806Gln) single nucleotide variant not specified [RCV004307409] Chr1:107574133 [GRCh38]
Chr1:108116755 [GRCh37]
Chr1:1p13.3		 uncertain significance
GRCh37/hg19 1p22.1-11.2(chr1:93837992-121343783)x3 copy number gain See cases [RCV000512354] Chr1:93837992..121343783 [GRCh37]
Chr1:1p22.1-11.2		 pathogenic
GRCh37/hg19 1p13.3(chr1:108317254-108817167)x3 copy number gain not provided [RCV000684611] Chr1:108317254..108817167 [GRCh37]
Chr1:1p13.3		 uncertain significance
GRCh37/hg19 1p13.3(chr1:107785595-108243838)x3 copy number gain not provided [RCV000684610] Chr1:107785595..108243838 [GRCh37]
Chr1:1p13.3		 uncertain significance
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
NC_000001.11:g.(?_103175204)_(111410059_?)del deletion Autism [RCV000754122] Chr1:103175204..111410059 [GRCh38]
Chr1:1p21.1-13.2		 likely pathogenic
GRCh37/hg19 1p22.1-13.3(chr1:94054724-111671707)x3 copy number gain not provided [RCV000749068] Chr1:94054724..111671707 [GRCh37]
Chr1:1p22.1-13.3		 pathogenic
GRCh37/hg19 1p13.3(chr1:108241166-108411688)x1 copy number loss not provided [RCV000749123] Chr1:108241166..108411688 [GRCh37]
Chr1:1p13.3		 benign
GRCh37/hg19 1p13.3(chr1:108393409-108405350)x1 copy number loss not provided [RCV000749124] Chr1:108393409..108405350 [GRCh37]
Chr1:1p13.3		 benign
GRCh37/hg19 1p13.3(chr1:108403028-108405350)x1 copy number loss not provided [RCV000749125] Chr1:108403028..108405350 [GRCh37]
Chr1:1p13.3		 benign
GRCh37/hg19 1p13.3(chr1:108403028-108408983)x1 copy number loss not provided [RCV000749126] Chr1:108403028..108408983 [GRCh37]
Chr1:1p13.3		 benign
NM_006113.5(VAV3):c.1188G>A (p.Leu396=) single nucleotide variant not provided [RCV000927411] Chr1:107751188 [GRCh38]
Chr1:108293810 [GRCh37]
Chr1:1p13.3		 likely benign
NM_006113.5(VAV3):c.1044G>A (p.Pro348=) single nucleotide variant not provided [RCV000950059] Chr1:107757303 [GRCh38]
Chr1:108299925 [GRCh37]
Chr1:1p13.3		 benign|likely benign
NM_006113.5(VAV3):c.834C>T (p.Tyr278=) single nucleotide variant not provided [RCV000950610] Chr1:107765163 [GRCh38]
Chr1:108307785 [GRCh37]
Chr1:1p13.3		 benign
NM_006113.5(VAV3):c.210C>T (p.Leu70=) single nucleotide variant not provided [RCV000906356] Chr1:107875012 [GRCh38]
Chr1:108417634 [GRCh37]
Chr1:1p13.3		 likely benign
NM_006113.5(VAV3):c.73T>C (p.Trp25Arg) single nucleotide variant not provided [RCV000881229] Chr1:107964797 [GRCh38]
Chr1:108507419 [GRCh37]
Chr1:1p13.3		 likely benign
NM_006113.5(VAV3):c.1374C>T (p.Thr458=) single nucleotide variant not provided [RCV000927342] Chr1:107749480 [GRCh38]
Chr1:108292102 [GRCh37]
Chr1:1p13.3		 likely benign
Single allele deletion 1p13.3 deletion syndrome [RCV000786772] Chr1:107779092..111199205 [GRCh37]
Chr1:1p13.3		 likely pathogenic
NM_006113.5(VAV3):c.2379C>T (p.Ala793=) single nucleotide variant not provided [RCV000920611] Chr1:107574170 [GRCh38]
Chr1:108116792 [GRCh37]
Chr1:1p13.3		 likely benign
NM_006113.5(VAV3):c.1515A>G (p.Arg505=) single nucleotide variant not provided [RCV000969402] Chr1:107705049 [GRCh38]
Chr1:108247671 [GRCh37]
Chr1:1p13.3		 benign
NM_006113.5(VAV3):c.9G>C (p.Pro3=) single nucleotide variant not provided [RCV000918154] Chr1:107964861 [GRCh38]
Chr1:108507483 [GRCh37]
Chr1:1p13.3		 likely benign
NM_006113.5(VAV3):c.718-10C>T single nucleotide variant not provided [RCV000894676] Chr1:107766560 [GRCh38]
Chr1:108309182 [GRCh37]
Chr1:1p13.3		 benign
NM_006113.5(VAV3):c.1136G>A (p.Arg379His) single nucleotide variant not provided [RCV000903568] Chr1:107755464 [GRCh38]
Chr1:108298086 [GRCh37]
Chr1:1p13.3		 likely benign
NM_006113.5(VAV3):c.9G>A (p.Pro3=) single nucleotide variant not provided [RCV000896824] Chr1:107964861 [GRCh38]
Chr1:108507483 [GRCh37]
Chr1:1p13.3		 benign
NM_006113.5(VAV3):c.408T>C (p.Asn136=) single nucleotide variant not provided [RCV000958479] Chr1:107777269 [GRCh38]
Chr1:108319891 [GRCh37]
Chr1:1p13.3		 benign
GRCh37/hg19 1p13.3(chr1:108231422-108474521)x1 copy number loss not provided [RCV000845989] Chr1:108231422..108474521 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.415G>A (p.Asp139Asn) single nucleotide variant not provided [RCV000969403] Chr1:107777262 [GRCh38]
Chr1:108319884 [GRCh37]
Chr1:1p13.3		 benign
NM_006113.5(VAV3):c.2011C>A (p.Pro671Thr) single nucleotide variant not provided [RCV000952854] Chr1:107609935 [GRCh38]
Chr1:108152557 [GRCh37]
Chr1:1p13.3		 likely benign
NM_006113.5(VAV3):c.295T>C (p.Leu99=) single nucleotide variant not provided [RCV000885442] Chr1:107874927 [GRCh38]
Chr1:108417549 [GRCh37]
Chr1:1p13.3		 benign
NM_006113.5(VAV3):c.2456C>T (p.Thr819Ile) single nucleotide variant not provided [RCV000921879] Chr1:107574093 [GRCh38]
Chr1:108116715 [GRCh37]
Chr1:1p13.3		 likely benign
NM_006113.5(VAV3):c.2132+8G>T single nucleotide variant not provided [RCV000910966] Chr1:107603039 [GRCh38]
Chr1:108145661 [GRCh37]
Chr1:1p13.3		 benign
NM_006113.5(VAV3):c.2502+8G>A single nucleotide variant not provided [RCV000890655] Chr1:107574039 [GRCh38]
Chr1:108116661 [GRCh37]
Chr1:1p13.3		 benign
GRCh37/hg19 1p13.3(chr1:108064478-108392992)x3 copy number gain not provided [RCV002473461] Chr1:108064478..108392992 [GRCh37]
Chr1:1p13.3		 uncertain significance
GRCh37/hg19 1p21.2-12(chr1:102021465-119737478) copy number loss Seizure [RCV001352640] Chr1:102021465..119737478 [GRCh37]
Chr1:1p21.2-12		 pathogenic
GRCh37/hg19 1p13.3(chr1:108346477-110177123)x1 copy number loss not provided [RCV001827629] Chr1:108346477..110177123 [GRCh37]
Chr1:1p13.3		 uncertain significance
GRCh37/hg19 1p21.3-13.2(chr1:95046805-114714931) copy number loss not specified [RCV002053503] Chr1:95046805..114714931 [GRCh37]
Chr1:1p21.3-13.2		 pathogenic
GRCh37/hg19 1p13.3(chr1:108084038-108946133)x3 copy number gain not provided [RCV002474756] Chr1:108084038..108946133 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.307C>G (p.Arg103Gly) single nucleotide variant not specified [RCV004207655] Chr1:107874915 [GRCh38]
Chr1:108417537 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1810T>C (p.Ser604Pro) single nucleotide variant not specified [RCV004202876] Chr1:107642723 [GRCh38]
Chr1:108185345 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1223G>A (p.Arg408Gln) single nucleotide variant not specified [RCV004200701] Chr1:107751153 [GRCh38]
Chr1:108293775 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.853G>T (p.Val285Leu) single nucleotide variant not specified [RCV004144141] Chr1:107765144 [GRCh38]
Chr1:108307766 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1282G>A (p.Ala428Thr) single nucleotide variant not specified [RCV004120870] Chr1:107749572 [GRCh38]
Chr1:108292194 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.2162T>C (p.Ile721Thr) single nucleotide variant not specified [RCV004163988] Chr1:107602455 [GRCh38]
Chr1:108145077 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1291G>A (p.Val431Ile) single nucleotide variant not specified [RCV004247147] Chr1:107749563 [GRCh38]
Chr1:108292185 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.154G>A (p.Ala52Thr) single nucleotide variant not specified [RCV004216375] Chr1:107964716 [GRCh38]
Chr1:108507338 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.2383G>A (p.Ala795Thr) single nucleotide variant not specified [RCV004094886] Chr1:107574166 [GRCh38]
Chr1:108116788 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1400A>G (p.Tyr467Cys) single nucleotide variant not specified [RCV004095987] Chr1:107749070 [GRCh38]
Chr1:108291692 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.622A>G (p.Thr208Ala) single nucleotide variant not specified [RCV004117024] Chr1:107770662 [GRCh38]
Chr1:108313284 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.2327G>A (p.Arg776Lys) single nucleotide variant not specified [RCV004115648] Chr1:107596235 [GRCh38]
Chr1:108138857 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.165C>G (p.Ile55Met) single nucleotide variant not specified [RCV004171788] Chr1:107964705 [GRCh38]
Chr1:108507327 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.623C>T (p.Thr208Ile) single nucleotide variant not specified [RCV004180775] Chr1:107770661 [GRCh38]
Chr1:108313283 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.2041C>A (p.Gln681Lys) single nucleotide variant not specified [RCV004172460] Chr1:107603138 [GRCh38]
Chr1:108145760 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1750C>G (p.Arg584Gly) single nucleotide variant not specified [RCV004176066] Chr1:107683515 [GRCh38]
Chr1:108226137 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.814A>G (p.Lys272Glu) single nucleotide variant not specified [RCV004090361] Chr1:107766454 [GRCh38]
Chr1:108309076 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1841G>A (p.Gly614Glu) single nucleotide variant not specified [RCV004221077] Chr1:107642692 [GRCh38]
Chr1:108185314 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.71C>T (p.Thr24Ile) single nucleotide variant not specified [RCV004077568] Chr1:107964799 [GRCh38]
Chr1:108507421 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.2291T>A (p.Phe764Tyr) single nucleotide variant not specified [RCV004267358] Chr1:107596271 [GRCh38]
Chr1:108138893 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1262A>G (p.His421Arg) single nucleotide variant not specified [RCV004261546] Chr1:107749592 [GRCh38]
Chr1:108292214 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1265T>A (p.Ile422Asn) single nucleotide variant not specified [RCV004249175] Chr1:107749589 [GRCh38]
Chr1:108292211 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.728A>G (p.Lys243Arg) single nucleotide variant not specified [RCV004343787] Chr1:107766540 [GRCh38]
Chr1:108309162 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.163A>G (p.Ile55Val) single nucleotide variant not specified [RCV004360185] Chr1:107964707 [GRCh38]
Chr1:108507329 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1424A>G (p.Gln475Arg) single nucleotide variant not specified [RCV004334825] Chr1:107749046 [GRCh38]
Chr1:108291668 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.67G>A (p.Val23Met) single nucleotide variant not specified [RCV004480217] Chr1:107964803 [GRCh38]
Chr1:108507425 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.283G>A (p.Glu95Lys) single nucleotide variant not specified [RCV004480213] Chr1:107874939 [GRCh38]
Chr1:108417561 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.278T>G (p.Leu93Arg) single nucleotide variant not specified [RCV004480212] Chr1:107874944 [GRCh38]
Chr1:108417566 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.2098A>G (p.Thr700Ala) single nucleotide variant not specified [RCV004480211] Chr1:107603081 [GRCh38]
Chr1:108145703 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.19T>G (p.Cys7Gly) single nucleotide variant not specified [RCV004480210] Chr1:107964851 [GRCh38]
Chr1:108507473 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.106A>G (p.Thr36Ala) single nucleotide variant not specified [RCV004480200] Chr1:107964764 [GRCh38]
Chr1:108507386 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1135C>T (p.Arg379Cys) single nucleotide variant not specified [RCV004480201] Chr1:107755465 [GRCh38]
Chr1:108298087 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1358C>G (p.Ala453Gly) single nucleotide variant not specified [RCV004480202] Chr1:107749496 [GRCh38]
Chr1:108292118 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1714A>G (p.Thr572Ala) single nucleotide variant not specified [RCV004480203] Chr1:107688398 [GRCh38]
Chr1:108231020 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1828G>A (p.Ala610Thr) single nucleotide variant not specified [RCV004480205] Chr1:107642705 [GRCh38]
Chr1:108185327 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1892A>G (p.Asp631Gly) single nucleotide variant not specified [RCV004480206] Chr1:107642641 [GRCh38]
Chr1:108185263 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1895C>T (p.Ala632Val) single nucleotide variant not specified [RCV004480207] Chr1:107642638 [GRCh38]
Chr1:108185260 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1912C>G (p.Gln638Glu) single nucleotide variant not specified [RCV004480208] Chr1:107642621 [GRCh38]
Chr1:108185243 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.1969C>G (p.Pro657Ala) single nucleotide variant not specified [RCV004480209] Chr1:107617578 [GRCh38]
Chr1:108160200 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.989G>A (p.Arg330His) single nucleotide variant not specified [RCV004480218] Chr1:107760812 [GRCh38]
Chr1:108303434 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.397G>C (p.Glu133Gln) single nucleotide variant not specified [RCV004480216] Chr1:107777280 [GRCh38]
Chr1:108319902 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.308G>A (p.Arg103His) single nucleotide variant not specified [RCV004480215] Chr1:107874914 [GRCh38]
Chr1:108417536 [GRCh37]
Chr1:1p13.3		 uncertain significance
NM_006113.5(VAV3):c.299T>C (p.Phe100Ser) single nucleotide variant not specified [RCV004480214] Chr1:107874923 [GRCh38]
Chr1:108417545 [GRCh37]
Chr1:1p13.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4456
Count of miRNA genes:1144
Interacting mature miRNAs:1403
Transcripts:ENST00000343258, ENST00000370056, ENST00000371846, ENST00000415432, ENST00000469325, ENST00000479977, ENST00000490388, ENST00000524574, ENST00000525231, ENST00000525460, ENST00000527011, ENST00000529033, ENST00000529413, ENST00000529809, ENST00000530671, ENST00000533398, ENST00000544443
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-75257  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371108,114,653 - 108,114,813UniSTSGRCh37
Build 361107,916,176 - 107,916,336RGDNCBI36
Celera1106,289,389 - 106,289,549RGD
Cytogenetic Map1p13.3UniSTS
HuRef1106,060,562 - 106,060,722UniSTS
GeneMap99-GB4 RH Map1335.99UniSTS
D1S1574  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371108,469,785 - 108,469,914UniSTSGRCh37
Build 361108,271,308 - 108,271,437RGDNCBI36
Celera1106,644,494 - 106,644,623RGD
Cytogenetic Map1p13.3UniSTS
HuRef1106,415,559 - 106,415,688UniSTS
AL033681  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371108,497,374 - 108,497,511UniSTSGRCh37
Build 361108,298,897 - 108,299,034RGDNCBI36
Celera1106,672,087 - 106,672,224RGD
Cytogenetic Map1p13.3UniSTS
HuRef1106,443,151 - 106,443,288UniSTS
AL033925  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371108,285,733 - 108,285,882UniSTSGRCh37
Build 361108,087,256 - 108,087,405RGDNCBI36
Celera1106,460,434 - 106,460,583RGD
Cytogenetic Map1p13.3UniSTS
HuRef1106,231,536 - 106,231,685UniSTS
SHGC-83256  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371108,151,321 - 108,151,643UniSTSGRCh37
Build 361107,952,844 - 107,953,166RGDNCBI36
Celera1106,326,055 - 106,326,377RGD
Cytogenetic Map1p13.3UniSTS
HuRef1106,097,225 - 106,097,547UniSTS
RH119571  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371108,334,807 - 108,334,967UniSTSGRCh37
Build 361108,136,330 - 108,136,490RGDNCBI36
Celera1106,509,509 - 106,509,669RGD
Cytogenetic Map1p13.3UniSTS
HuRef1106,280,608 - 106,280,768UniSTS
TNG Radiation Hybrid Map158921.0UniSTS
SHGC-145896  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371108,408,076 - 108,408,356UniSTSGRCh37
Build 361108,209,599 - 108,209,879RGDNCBI36
Celera1106,582,774 - 106,583,054RGD
Cytogenetic Map1p13.3UniSTS
HuRef1106,353,846 - 106,354,126UniSTS
TNG Radiation Hybrid Map158962.0UniSTS
AL009945  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371108,369,325 - 108,369,486UniSTSGRCh37
Build 361108,170,848 - 108,171,009RGDNCBI36
Celera1106,544,023 - 106,544,184RGD
Cytogenetic Map1p13.3UniSTS
HuRef1106,315,092 - 106,315,253UniSTS
AL009700  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371108,361,419 - 108,361,607UniSTSGRCh37
Build 361108,162,942 - 108,163,130RGDNCBI36
Celera1106,536,121 - 106,536,309RGD
Cytogenetic Map1p13.3UniSTS
HuRef1106,307,241 - 106,307,429UniSTS
STS-AA009655  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371108,114,654 - 108,114,899UniSTSGRCh37
Build 361107,916,177 - 107,916,422RGDNCBI36
Celera1106,289,390 - 106,289,635RGD
Cytogenetic Map1p13.3UniSTS
HuRef1106,060,563 - 106,060,808UniSTS
GeneMap99-GB4 RH Map1334.22UniSTS
SHGC-75253  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1p13.3UniSTS
HuRef1106,059,935 - 106,060,070UniSTS
GeneMap99-GB4 RH Map1334.33UniSTS
NCBI RH Map1832.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 407 206 111 47 626 18 1336 10 40 350 316 181 34 2 697 2
Low 1909 2189 1441 421 948 291 2032 1139 3254 56 1008 1346 139 1 1202 1130 4 1
Below cutoff 83 590 165 152 227 152 981 1042 407 5 123 47 1 961

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001079874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005270360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005270361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017000053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017000054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017000055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017000056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024450319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047430439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047430476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047430543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047430555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054333836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054333837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054333838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054333839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054333840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054333841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054333842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054333843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054333844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054333845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054333846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001736913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007063680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF035442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF067817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF118886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF118887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI304566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK097750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK295166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK300474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK316295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL353892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL391235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL513206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL591042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DR002311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000343258
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,573,169 - 107,785,624 (-)Ensembl
RefSeq Acc Id: ENST00000370056   ⟹   ENSP00000359073
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,571,161 - 107,965,180 (-)Ensembl
RefSeq Acc Id: ENST00000415432   ⟹   ENSP00000394897
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,572,975 - 107,688,504 (-)Ensembl
RefSeq Acc Id: ENST00000469325
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,668,839 - 107,963,596 (-)Ensembl
RefSeq Acc Id: ENST00000479977
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,609,814 - 107,688,528 (-)Ensembl
RefSeq Acc Id: ENST00000490388   ⟹   ENSP00000433559
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,668,963 - 107,964,853 (-)Ensembl
RefSeq Acc Id: ENST00000524574
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,766,515 - 107,820,896 (-)Ensembl
RefSeq Acc Id: ENST00000525231   ⟹   ENSP00000434944
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,603,097 - 107,688,504 (-)Ensembl
RefSeq Acc Id: ENST00000525460
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,572,950 - 107,678,009 (-)Ensembl
RefSeq Acc Id: ENST00000527011   ⟹   ENSP00000432540
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,571,589 - 107,965,009 (-)Ensembl
RefSeq Acc Id: ENST00000529033
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,596,295 - 107,673,649 (-)Ensembl
RefSeq Acc Id: ENST00000529413   ⟹   ENSP00000432865
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,572,848 - 107,688,504 (-)Ensembl
RefSeq Acc Id: ENST00000529809   ⟹   ENSP00000431544
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,617,584 - 107,749,508 (-)Ensembl
RefSeq Acc Id: ENST00000530671
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,770,659 - 107,963,500 (-)Ensembl
RefSeq Acc Id: ENST00000533398
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1107,617,567 - 107,685,952 (-)Ensembl
RefSeq Acc Id: NM_001079874   ⟹   NP_001073343
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,571,161 - 107,688,499 (-)NCBI
GRCh371108,113,782 - 108,507,545 (-)ENTREZGENE
Build 361107,915,305 - 108,032,649 (-)NCBI Archive
HuRef1106,059,691 - 106,453,322 (-)ENTREZGENE
CHM1_11108,228,649 - 108,345,966 (-)NCBI
T2T-CHM13v2.01107,608,692 - 107,725,975 (-)NCBI
Sequence:
RefSeq Acc Id: NM_006113   ⟹   NP_006104
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,571,161 - 107,965,180 (-)NCBI
GRCh371108,113,782 - 108,507,545 (-)ENTREZGENE
Build 361107,915,305 - 108,309,068 (-)NCBI Archive
HuRef1106,059,691 - 106,453,322 (-)ENTREZGENE
CHM1_11108,228,649 - 108,622,362 (-)NCBI
T2T-CHM13v2.01107,608,692 - 108,002,653 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005270360   ⟹   XP_005270417
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,571,161 - 107,786,534 (-)NCBI
GRCh371108,113,782 - 108,507,545 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005270361   ⟹   XP_005270418
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,668,839 - 107,965,180 (-)NCBI
GRCh371108,113,782 - 108,507,545 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017000053   ⟹   XP_016855542
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,571,161 - 107,965,180 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017000054   ⟹   XP_016855543
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,578,295 - 107,965,180 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017000055   ⟹   XP_016855544
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,571,161 - 107,786,640 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017000056   ⟹   XP_016855545
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,571,161 - 107,754,865 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024450319   ⟹   XP_024306087
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,571,161 - 107,964,355 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047430439   ⟹   XP_047286395
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,571,161 - 107,783,006 (-)NCBI
RefSeq Acc Id: XM_047430476   ⟹   XP_047286432
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,571,161 - 107,827,357 (-)NCBI
RefSeq Acc Id: XM_047430543   ⟹   XP_047286499
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,642,620 - 107,965,180 (-)NCBI
RefSeq Acc Id: XM_047430555   ⟹   XP_047286511
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,668,839 - 107,786,534 (-)NCBI
RefSeq Acc Id: XM_054333836   ⟹   XP_054189811
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01107,608,692 - 108,002,653 (-)NCBI
RefSeq Acc Id: XM_054333837   ⟹   XP_054189812
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01107,617,951 - 108,002,653 (-)NCBI
RefSeq Acc Id: XM_054333838   ⟹   XP_054189813
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01107,608,692 - 108,001,831 (-)NCBI
RefSeq Acc Id: XM_054333839   ⟹   XP_054189814
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01107,608,692 - 107,823,168 (-)NCBI
RefSeq Acc Id: XM_054333840   ⟹   XP_054189815
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01107,608,692 - 107,824,112 (-)NCBI
RefSeq Acc Id: XM_054333841   ⟹   XP_054189816
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01107,608,692 - 107,820,480 (-)NCBI
RefSeq Acc Id: XM_054333842   ⟹   XP_054189817
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01107,608,692 - 107,864,831 (-)NCBI
RefSeq Acc Id: XM_054333843   ⟹   XP_054189818
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01107,706,315 - 108,002,653 (-)NCBI
RefSeq Acc Id: XM_054333844   ⟹   XP_054189819
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01107,680,138 - 108,002,653 (-)NCBI
RefSeq Acc Id: XM_054333845   ⟹   XP_054189820
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01107,706,315 - 107,823,308 (-)NCBI
RefSeq Acc Id: XM_054333846   ⟹   XP_054189821
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01107,608,692 - 107,792,335 (-)NCBI
RefSeq Acc Id: XR_007063680
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,578,295 - 107,965,180 (-)NCBI
RefSeq Acc Id: XR_008485864
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01107,617,951 - 108,002,653 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001073343 (Get FASTA)   NCBI Sequence Viewer  
  NP_006104 (Get FASTA)   NCBI Sequence Viewer  
  XP_005270417 (Get FASTA)   NCBI Sequence Viewer  
  XP_005270418 (Get FASTA)   NCBI Sequence Viewer  
  XP_016855542 (Get FASTA)   NCBI Sequence Viewer  
  XP_016855543 (Get FASTA)   NCBI Sequence Viewer  
  XP_016855544 (Get FASTA)   NCBI Sequence Viewer  
  XP_016855545 (Get FASTA)   NCBI Sequence Viewer  
  XP_024306087 (Get FASTA)   NCBI Sequence Viewer  
  XP_047286395 (Get FASTA)   NCBI Sequence Viewer  
  XP_047286432 (Get FASTA)   NCBI Sequence Viewer  
  XP_047286499 (Get FASTA)   NCBI Sequence Viewer  
  XP_047286511 (Get FASTA)   NCBI Sequence Viewer  
  XP_054189811 (Get FASTA)   NCBI Sequence Viewer  
  XP_054189812 (Get FASTA)   NCBI Sequence Viewer  
  XP_054189813 (Get FASTA)   NCBI Sequence Viewer  
  XP_054189814 (Get FASTA)   NCBI Sequence Viewer  
  XP_054189815 (Get FASTA)   NCBI Sequence Viewer  
  XP_054189816 (Get FASTA)   NCBI Sequence Viewer  
  XP_054189817 (Get FASTA)   NCBI Sequence Viewer  
  XP_054189818 (Get FASTA)   NCBI Sequence Viewer  
  XP_054189819 (Get FASTA)   NCBI Sequence Viewer  
  XP_054189820 (Get FASTA)   NCBI Sequence Viewer  
  XP_054189821 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC79695 (Get FASTA)   NCBI Sequence Viewer  
  AAD03799 (Get FASTA)   NCBI Sequence Viewer  
  AAD20348 (Get FASTA)   NCBI Sequence Viewer  
  AAD20349 (Get FASTA)   NCBI Sequence Viewer  
  AAI43970 (Get FASTA)   NCBI Sequence Viewer  
  BAG58178 (Get FASTA)   NCBI Sequence Viewer  
  BAG62191 (Get FASTA)   NCBI Sequence Viewer  
  BAG64994 (Get FASTA)   NCBI Sequence Viewer  
  BAH12381 (Get FASTA)   NCBI Sequence Viewer  
  BAH14666 (Get FASTA)   NCBI Sequence Viewer  
  EAW51251 (Get FASTA)   NCBI Sequence Viewer  
  EAW51252 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000359073
  ENSP00000359073.4
  ENSP00000394897
  ENSP00000394897.2
  ENSP00000431544.1
  ENSP00000432540.1
  ENSP00000432865.1
  ENSP00000433559
  ENSP00000433559.1
  ENSP00000434944.1
GenBank Protein Q9UKW4 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_006104   ⟸   NM_006113
- Peptide Label: isoform 1
- UniProtKB: O95230 (UniProtKB/Swiss-Prot),   O60498 (UniProtKB/Swiss-Prot),   E9PQ97 (UniProtKB/Swiss-Prot),   B7ZLR1 (UniProtKB/Swiss-Prot),   B4E232 (UniProtKB/Swiss-Prot),   B1APV5 (UniProtKB/Swiss-Prot),   B1AMM0 (UniProtKB/Swiss-Prot),   Q9Y5X8 (UniProtKB/Swiss-Prot),   Q9UKW4 (UniProtKB/Swiss-Prot),   A0A2X0U2Q1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001073343   ⟸   NM_001079874
- Peptide Label: isoform 2
- UniProtKB: B4DU29 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005270417   ⟸   XM_005270360
- Peptide Label: isoform X4
- UniProtKB: A0A2X0U2Q1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005270418   ⟸   XM_005270361
- Peptide Label: isoform X7
- UniProtKB: H0YDG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016855542   ⟸   XM_017000053
- Peptide Label: isoform X1
- UniProtKB: A0A2X0U2Q1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016855544   ⟸   XM_017000055
- Peptide Label: isoform X5
- UniProtKB: A0A2X0U2Q1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016855545   ⟸   XM_017000056
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_016855543   ⟸   XM_017000054
- Peptide Label: isoform X2
- UniProtKB: A0A2X0U2Q1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024306087   ⟸   XM_024450319
- Peptide Label: isoform X3
- UniProtKB: A0A2X0U2Q1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000359073   ⟸   ENST00000370056
RefSeq Acc Id: ENSP00000433559   ⟸   ENST00000490388
RefSeq Acc Id: ENSP00000394897   ⟸   ENST00000415432
RefSeq Acc Id: ENSP00000434944   ⟸   ENST00000525231
RefSeq Acc Id: ENSP00000432540   ⟸   ENST00000527011
RefSeq Acc Id: ENSP00000432865   ⟸   ENST00000529413
RefSeq Acc Id: ENSP00000431544   ⟸   ENST00000529809
RefSeq Acc Id: XP_047286432   ⟸   XM_047430476
- Peptide Label: isoform X6
RefSeq Acc Id: XP_047286395   ⟸   XM_047430439
- Peptide Label: isoform X6
RefSeq Acc Id: XP_047286499   ⟸   XM_047430543
- Peptide Label: isoform X8
RefSeq Acc Id: XP_047286511   ⟸   XM_047430555
- Peptide Label: isoform X9
RefSeq Acc Id: XP_054189811   ⟸   XM_054333836
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054189813   ⟸   XM_054333838
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054189817   ⟸   XM_054333842
- Peptide Label: isoform X6
RefSeq Acc Id: XP_054189815   ⟸   XM_054333840
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054189814   ⟸   XM_054333839
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054189816   ⟸   XM_054333841
- Peptide Label: isoform X6
RefSeq Acc Id: XP_054189821   ⟸   XM_054333846
- Peptide Label: isoform X10
RefSeq Acc Id: XP_054189812   ⟸   XM_054333837
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054189819   ⟸   XM_054333844
- Peptide Label: isoform X8
RefSeq Acc Id: XP_054189818   ⟸   XM_054333843
- Peptide Label: isoform X7
RefSeq Acc Id: XP_054189820   ⟸   XM_054333845
- Peptide Label: isoform X9
Protein Domains
Calponin-homology (CH)   DH   PH   Phorbol-ester/DAG-type   SH2   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9UKW4-F1-model_v2 AlphaFold Q9UKW4 1-847 view protein structure

Promoters
RGD ID:6856428
Promoter ID:EPDNEW_H1379
Type:initiation region
Name:VAV3_1
Description:vav guanine nucleotide exchange factor 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H1380  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,688,499 - 107,688,559EPDNEW
RGD ID:6856442
Promoter ID:EPDNEW_H1380
Type:initiation region
Name:VAV3_2
Description:vav guanine nucleotide exchange factor 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H1379  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381107,965,180 - 107,965,240EPDNEW
RGD ID:6787209
Promoter ID:HG_KWN:3908
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3
Transcripts:NM_001079874,   OTTHUMT00000030246
Position:
Human AssemblyChrPosition (strand)Source
Build 361108,032,396 - 108,032,896 (-)MPROMDB
RGD ID:6787210
Promoter ID:HG_KWN:3910
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   Jurkat,   Lymphoblastoid
Transcripts:OTTHUMT00000030244
Position:
Human AssemblyChrPosition (strand)Source
Build 361108,307,946 - 108,308,446 (-)MPROMDB
RGD ID:6787211
Promoter ID:HG_KWN:3912
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   Jurkat,   NB4
Transcripts:OTTHUMT00000030242,   OTTHUMT00000030245
Position:
Human AssemblyChrPosition (strand)Source
Build 361108,308,866 - 108,310,067 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:12659 AgrOrtholog
COSMIC VAV3 COSMIC
Ensembl Genes ENSG00000134215 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000370056 ENTREZGENE
  ENST00000370056.9 UniProtKB/Swiss-Prot
  ENST00000415432 ENTREZGENE
  ENST00000415432.6 UniProtKB/Swiss-Prot
  ENST00000490388 ENTREZGENE
  ENST00000490388.2 UniProtKB/TrEMBL
  ENST00000525231.5 UniProtKB/TrEMBL
  ENST00000527011.5 UniProtKB/Swiss-Prot
  ENST00000529413.5 UniProtKB/TrEMBL
  ENST00000529809.5 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.900.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000134215 GTEx
HGNC ID HGNC:12659 ENTREZGENE
Human Proteome Map VAV3 Human Proteome Map
InterPro CAMSAP_CH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CH-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DBL_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DH-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GDS_CDC24_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_Vav UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM22_calponin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VAV3_SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VAV3_SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VAV3_SH3_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10451 UniProtKB/Swiss-Prot
NCBI Gene 10451 ENTREZGENE
OMIM 605541 OMIM
PANTHER GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN VAV UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAMSAP_CH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA37282 PharmGKB
PRINTS SH2DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM22CALPONIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPECTRNALPHA UniProtKB/TrEMBL
PROSITE DH_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DH_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50021 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RhoGEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00033 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47576 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48065 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2X0U2Q1 ENTREZGENE, UniProtKB/TrEMBL
  B1AMM0 ENTREZGENE
  B1APV5 ENTREZGENE
  B4DU29 ENTREZGENE, UniProtKB/TrEMBL
  B4E232 ENTREZGENE
  B7ZLR1 ENTREZGENE
  E9PMJ5_HUMAN UniProtKB/TrEMBL
  E9PQ97 ENTREZGENE
  H0YCG7_HUMAN UniProtKB/TrEMBL
  H0YDG2 ENTREZGENE, UniProtKB/TrEMBL
  O60498 ENTREZGENE
  O95230 ENTREZGENE
  Q9UKW4 ENTREZGENE
  Q9Y5X8 ENTREZGENE
  VAV3_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B1AMM0 UniProtKB/Swiss-Prot
  B1APV5 UniProtKB/Swiss-Prot
  B4E232 UniProtKB/Swiss-Prot
  B7ZLR1 UniProtKB/Swiss-Prot
  E9PQ97 UniProtKB/Swiss-Prot
  O60498 UniProtKB/Swiss-Prot
  O95230 UniProtKB/Swiss-Prot
  Q9Y5X8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-01 VAV3  vav guanine nucleotide exchange factor 3  VAV3  vav 3 guanine nucleotide exchange factor  Symbol and/or name change 5135510 APPROVED