Orai1 (ORAI calcium release-activated calcium modulator 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Orai1 (ORAI calcium release-activated calcium modulator 1) Rattus norvegicus
Analyze
Symbol: Orai1
Name: ORAI calcium release-activated calcium modulator 1
RGD ID: 1311873
Description: Enables store-operated calcium channel activity. Involved in store-operated calcium entry. Located in growth cone. Human ortholog(s) of this gene implicated in immunodeficiency 9 and tubular aggregate myopathy 2. Orthologous to human ORAI1 (ORAI calcium release-activated calcium modulator 1); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: calcium release-activated calcium channel protein 1; calcium release-activated calcium modulator 1; LOC304496; protein orai-1; RGD1311873; similar to hypothetical protein FLJ14466; transmembrane protein 142A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81239,195,139 - 39,209,030 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1239,195,163 - 39,209,408 (-)EnsemblGRCr8
mRatBN7.21233,533,151 - 33,548,361 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1233,534,344 - 33,548,405 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1234,713,038 - 34,727,066 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01235,324,404 - 35,338,430 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01234,376,303 - 34,390,334 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01238,981,903 - 38,995,570 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1238,981,927 - 38,995,570 (-)Ensemblrn6Rnor6.0
Rnor_5.01240,878,296 - 40,879,065 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41234,631,248 - 34,646,316 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1235,214,491 - 35,228,150 (-)NCBICelera
RGSC_v3.11234,494,636 - 34,509,704 (-)NCBI
Cytogenetic Map12q16NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
basolateral plasma membrane  (IEA,ISO)
cell periphery  (IEA,ISO)
growth cone  (IDA)
membrane  (IBA,ISO)
membrane raft  (IEA,ISO,ISS)
plasma membrane  (IEA,ISO,ISS)
plasma membrane raft  (IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Store-operated Ca2+ entry in sensory neurons: functional role and the effect of painful nerve injury. Gemes G, etal., J Neurosci. 2011 Mar 9;31(10):3536-49.
3. Native STIM2 and ORAI1 proteins form a calcium-sensitive and thapsigargin-insensitive complex in cortical neurons. Gruszczynska-Biegala J and Kuznicki J, J Neurochem. 2013 Sep;126(6):727-38. doi: 10.1111/jnc.12320. Epub 2013 Jun 12.
4. Differential roles for STIM1 and STIM2 in store-operated calcium entry in rat neurons. Gruszczynska-Biegala J, etal., PLoS One. 2011 Apr 26;6(4):e19285.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. STIM1 is necessary for store-operated calcium entry in turning growth cones. Mitchell CB, etal., J Neurochem. 2012 Sep;122(6):1155-66. doi: 10.1111/j.1471-4159.2012.07840.x. Epub 2012 Jul 11.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. STIM proteins: dynamic calcium signal transducers. Soboloff J, etal., Nat Rev Mol Cell Biol. 2012 Sep;13(9):549-65. doi: 10.1038/nrm3414.
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13. Elevated Orai1 and STIM1 expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer. Xia J, etal., Cancer Lett. 2016 Oct 10;381(1):31-40. doi: 10.1016/j.canlet.2016.07.014. Epub 2016 Jul 16.
Additional References at PubMed
PMID:15489334   PMID:16645049   PMID:16733527   PMID:16766533   PMID:16807233   PMID:16921383   PMID:17224452   PMID:17343823   PMID:18711860   PMID:18757751   PMID:18768920   PMID:18845811  
PMID:18987344   PMID:19075091   PMID:19171672   PMID:19189966   PMID:19249086   PMID:19364762   PMID:19946888   PMID:20018736   PMID:20107038   PMID:20138887   PMID:20194792   PMID:20418871  
PMID:20929813   PMID:21330611   PMID:21730292   PMID:21737791   PMID:21750194   PMID:21945734   PMID:21966957   PMID:22050845   PMID:22108917   PMID:22494970   PMID:22534489   PMID:22684549  
PMID:22859829   PMID:22944608   PMID:23169006   PMID:23307288   PMID:23334602   PMID:23349245   PMID:23620825   PMID:23840669   PMID:23878392   PMID:24509424   PMID:24996186   PMID:25428882  
PMID:25540197   PMID:25636074   PMID:25873305   PMID:26033013   PMID:26494622   PMID:26755740   PMID:27025854   PMID:27099074   PMID:27129253   PMID:27185316   PMID:27393042   PMID:27503411  
PMID:28105751   PMID:28155613   PMID:28189550   PMID:28219928   PMID:28698564   PMID:29101179   PMID:29532875   PMID:29634917   PMID:29654766   PMID:29913436   PMID:30589833   PMID:31009360  
PMID:31009446   PMID:31415242   PMID:31926404   PMID:32075490   PMID:32146159   PMID:33269647   PMID:37533369   PMID:37686206   PMID:38291755   PMID:38514055  


Genomics

Comparative Map Data
Orai1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81239,195,139 - 39,209,030 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1239,195,163 - 39,209,408 (-)EnsemblGRCr8
mRatBN7.21233,533,151 - 33,548,361 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1233,534,344 - 33,548,405 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1234,713,038 - 34,727,066 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01235,324,404 - 35,338,430 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01234,376,303 - 34,390,334 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01238,981,903 - 38,995,570 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1238,981,927 - 38,995,570 (-)Ensemblrn6Rnor6.0
Rnor_5.01240,878,296 - 40,879,065 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41234,631,248 - 34,646,316 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1235,214,491 - 35,228,150 (-)NCBICelera
RGSC_v3.11234,494,636 - 34,509,704 (-)NCBI
Cytogenetic Map12q16NCBI
ORAI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812121,626,530 - 121,643,109 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12121,626,509 - 121,643,109 (+)Ensemblhg38GRCh38
GRCh3712122,064,435 - 122,081,015 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612120,548,858 - 120,564,322 (+)NCBIBuild 36Build 36hg18NCBI36
Celera12121,703,577 - 121,719,069 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12119,077,074 - 119,092,406 (+)NCBIHuRef
CHM1_112122,032,834 - 122,048,313 (+)NCBICHM1_1
T2T-CHM13v2.012121,619,725 - 121,636,322 (+)NCBIT2T-CHM13v2.0
Orai1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395123,153,078 - 123,168,515 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5123,153,137 - 123,168,519 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385123,015,074 - 123,030,452 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5123,015,074 - 123,030,456 (+)Ensemblmm10GRCm38
MGSCv375123,465,083 - 123,480,461 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365123,275,691 - 123,290,773 (+)NCBIMGSCv36mm8
Celera5120,110,246 - 120,125,811 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map562.72NCBI
Orai1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554826,731,949 - 6,775,545 (-)Ensembl
ChiLan1.0NW_0049554826,731,949 - 6,746,095 (-)NCBIChiLan1.0ChiLan1.0
LOC100987781
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210129,715,796 - 129,730,170 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112129,712,187 - 129,726,546 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012119,229,069 - 119,243,435 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112122,601,227 - 122,614,990 (+)NCBIPanPan1.1PanPan1.1panPan2
ORAI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1267,584,276 - 7,599,667 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl267,584,880 - 7,599,401 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha267,743,828 - 7,758,883 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0267,836,101 - 7,851,163 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl267,836,598 - 7,881,528 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1267,767,621 - 7,782,778 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0267,857,940 - 7,873,138 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,813,894 - 7,829,022 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Orai1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118156,736,358 - 156,749,328 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365582,730,098 - 2,743,062 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ORAI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1431,011,644 - 31,027,993 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11431,012,212 - 31,028,008 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21432,817,278 - 32,818,011 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21432,882,749 - 32,883,075 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103239286
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111116,997,375 - 117,012,115 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11116,997,636 - 117,011,737 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037127,968,411 - 127,985,052 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Orai1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474722,071,404 - 22,085,976 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474722,071,373 - 22,085,180 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Orai1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11630,793,006 - 30,808,209 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Orai1
92 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:52
Count of miRNA genes:50
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000001806
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771850386405Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123776414551558799Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122977552242298555Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)123370043246784661Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)123370043246784661Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)123370043251558799Rat
631829Alc6Alcohol consumption QTL 64.7consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)123424347543352593Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
8693658Alc33Alcohol consumption QTL 332.10.68drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122871771849212240Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000001806   ⟹   ENSRNOP00000001806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1239,195,163 - 39,209,408 (-)Ensembl
mRatBN7.2 Ensembl1233,534,344 - 33,548,405 (-)Ensembl
Rnor_6.0 Ensembl1238,981,927 - 38,995,570 (-)Ensembl
RefSeq Acc Id: NM_001013982   ⟹   NP_001014004
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81239,195,139 - 39,209,030 (-)NCBI
mRatBN7.21233,534,320 - 33,548,212 (-)NCBI
Rnor_6.01238,981,903 - 38,995,570 (-)NCBI
Rnor_5.01240,878,296 - 40,879,065 (-)NCBI
RGSC_v3.41234,631,248 - 34,646,316 (-)RGD
Celera1235,214,491 - 35,228,150 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001014004 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88225 (Get FASTA)   NCBI Sequence Viewer  
  ACD02426 (Get FASTA)   NCBI Sequence Viewer  
  Q5M848 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001014004   ⟸   NM_001013982
- UniProtKB: Q5M848 (UniProtKB/Swiss-Prot),   B2ZDP8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001806   ⟸   ENSRNOT00000001806

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M848-F1-model_v2 AlphaFold Q5M848 1-304 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698639
Promoter ID:EPDNEW_R9160
Type:initiation region
Name:Orai1_1
Description:ORAI calcium release-activated calcium modulator 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01238,995,659 - 38,995,719EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311873 AgrOrtholog
BioCyc Gene G2FUF-19283 BioCyc
Ensembl Genes ENSRNOG00000001336 Ensembl
Gene3D-CATH 1.20.140.140 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7322176 IMAGE-MGC_LOAD
InterPro CRAC_channel UniProtKB/Swiss-Prot
  Orai_sf UniProtKB/Swiss-Prot
KEGG Report rno:304496 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108979 IMAGE-MGC_LOAD
NCBI Gene 304496 ENTREZGENE
PANTHER CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 UniProtKB/Swiss-Prot
  PTHR31501 UniProtKB/Swiss-Prot
Pfam Orai-1 UniProtKB/Swiss-Prot
PhenoGen Orai1 PhenoGen
RatGTEx ENSRNOG00000001336 RatGTEx
UniProt B2ZDP8 ENTREZGENE, UniProtKB/TrEMBL
  CRCM1_RAT UniProtKB/Swiss-Prot
  F1LNX2_RAT UniProtKB/TrEMBL
  Q5M848 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-27 Orai1  ORAI calcium release-activated calcium modulator 1  RGD1311873  similar to hypothetical protein FLJ14466  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1311873  similar to hypothetical protein FLJ14466  RGD1311873_predicted  similar to hypothetical protein FLJ14466 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1311873_predicted  similar to hypothetical protein FLJ14466 (predicted)  LOC304496_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC304496_predicted  similar to hypothetical protein FLJ14466 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL