GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Orai1 | increases expression | EXP | | 6480464 | CTD | Ethanol results in increased expression of ORAI1 mRNA; Ethanol results in increased expression of ORAI1 protein | PMID:26033013 | Orai1 | multiple interactions | EXP | | 6480464 | CTD | 2,6-difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide inhibits the reaction [Ethanol results in increased expression of ORAI1 protein]; 2-aminoethyl diphenylborinate inhibits the reaction [Ethanol results in increased expression of ORAI1 protein]; corosolic acid inhibits the reaction [Ethanol results in increased expression of ORAI1 protein]; Lanthanoid Series Elements inhibits the reaction [Ethanol results in increased expression of ORAI1 protein]; ORAI1 protein affects the reaction [Ethanol results in increased cleavage of CASP3 protein] | PMID:26033013 | Orai1 | increases expression | ISO | ORAI1 (Homo sapiens) | 6480464 | CTD | Ethanol results in increased expression of ORAI1 mRNA; Ethanol results in increased expression of ORAI1 protein | PMID:22119170 | | ||||||||||||||||||||||
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