Cdc14b (cell division cycle 14B) - Rat Genome Database

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Pathways
Gene: Cdc14b (cell division cycle 14B) Rattus norvegicus
Analyze
Symbol: Cdc14b
Name: cell division cycle 14B
RGD ID: 1311163
Description: Predicted to enable protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Predicted to be involved in cilium assembly; microtubule cytoskeleton organization; and regulation of cell cycle process. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm; nucleolus; and spindle. Orthologous to several human genes including CDC14B (cell division cycle 14B); PARTICIPATES IN RNA polymerase II transcription pathway; cell cycle pathway, mitotic; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CDC14 cell division cycle 14 homolog B; CDC14 cell division cycle 14 homolog B (S. cerevisiae); dual specificity protein phosphatase CDC14B; LOC361195
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr817850,272 - 938,972 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl17850,390 - 971,164 (+)EnsemblGRCr8
mRatBN7.217844,686 - 934,787 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl17844,685 - 933,235 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx17863,396 - 946,159 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0172,405,971 - 2,488,735 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.017860,819 - 943,581 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0171,709,703 - 1,797,732 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,703,943 - 1,797,750 (-)Ensemblrn6Rnor6.0
Rnor_5.0171,699,259 - 1,787,005 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4176,371,204 - 6,454,460 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera171,589,728 - 1,671,876 (-)NCBICelera
RGSC_v3.1176,397,503 - 6,451,948 (+)NCBI
Cytogenetic Map17p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(+/-)-Aegeline  (ISO)
(1->4)-beta-D-glucan  (ISO)
(RS)-coclaurine  (ISO)
(RS)-norcoclaurine  (ISO)
(S)-coclaurine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitrophenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP)
bisphenol F  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calyculin A  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chrysene  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
folic acid  (ISO)
FR900359  (ISO)
GW 3965  (ISO)
isotretinoin  (ISO)
leflunomide  (ISO)
melphalan  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
okadaic acid  (ISO)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sulfadimethoxine  (EXP)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
yohimbine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
mitotic spindle  (IBA)
nucleolus  (IBA,ISO)
nucleoplasm  (ISO)
nucleus  (ISO)
spindle pole  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Updating the RNA polymerase CTD code: adding gene-specific layers. Egloff S, etal., Trends Genet. 2012 Jul;28(7):333-41. doi: 10.1016/j.tig.2012.03.007. Epub 2012 May 21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. The writers, readers, and functions of the RNA polymerase II C-terminal domain code. Jeronimo C, etal., Chem Rev. 2013 Nov 13;113(11):8491-522. doi: 10.1021/cr4001397. Epub 2013 Jul 10.
5. Loss of CDC14B expression in clear cell renal cell carcinoma: meta-analysis of microarray data sets. Kim Y, etal., Am J Clin Pathol. 2014 Apr;141(4):551-8. doi: 10.1309/AJCP4PE4JPSRGBQS.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Early-onset aging and defective DNA damage response in Cdc14b-deficient mice. Wei Z, etal., Mol Cell Biol. 2011 Apr;31(7):1470-7. doi: 10.1128/MCB.01330-10. Epub 2011 Jan 24.
Additional References at PubMed
PMID:9367992   PMID:18662541  


Genomics

Comparative Map Data
Cdc14b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr817850,272 - 938,972 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl17850,390 - 971,164 (+)EnsemblGRCr8
mRatBN7.217844,686 - 934,787 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl17844,685 - 933,235 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx17863,396 - 946,159 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0172,405,971 - 2,488,735 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.017860,819 - 943,581 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0171,709,703 - 1,797,732 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,703,943 - 1,797,750 (-)Ensemblrn6Rnor6.0
Rnor_5.0171,699,259 - 1,787,005 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4176,371,204 - 6,454,460 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera171,589,728 - 1,671,876 (-)NCBICelera
RGSC_v3.1176,397,503 - 6,451,948 (+)NCBI
Cytogenetic Map17p14NCBI
CDC14B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38996,490,939 - 96,619,843 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl996,490,241 - 96,619,855 (-)Ensemblhg38GRCh38
GRCh37999,262,390 - 99,382,125 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36998,302,216 - 98,421,933 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34996,332,077 - 96,461,667NCBI
Celera969,703,970 - 69,823,685 (-)NCBICelera
Cytogenetic Map9q22.32-q22.33NCBI
HuRef968,873,293 - 68,940,865 (-)NCBIHuRef
CHM1_1999,409,222 - 99,528,933 (-)NCBICHM1_1
T2T-CHM13v2.09108,663,606 - 108,791,618 (-)NCBIT2T-CHM13v2.0
Cdc14b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391364,337,085 - 64,423,670 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1364,337,082 - 64,423,104 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381364,192,545 - 64,274,988 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1364,189,268 - 64,275,290 (-)Ensemblmm10GRCm38
MGSCv371364,293,853 - 64,376,296 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361364,204,559 - 64,284,140 (-)NCBIMGSCv36mm8
Celera1365,855,813 - 65,939,623 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1333.26NCBI
Cdc14b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542223,303,250 - 23,322,493 (+)Ensembl
ChiLan1.0 EnsemblNW_00495542223,383,270 - 23,441,323 (+)Ensembl
ChiLan1.0NW_00495542223,303,472 - 23,445,785 (+)NCBIChiLan1.0ChiLan1.0
CDC14B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21142,829,615 - 42,951,928 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1942,831,971 - 42,954,311 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0967,596,037 - 67,715,668 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1995,717,715 - 95,784,114 (-)NCBIPanPan1.1PanPan1.1panPan2
CDC14B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1170,232,932 - 70,335,950 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl170,232,947 - 70,335,943 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha170,996,105 - 71,099,112 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0170,532,035 - 70,635,025 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl170,532,050 - 70,635,018 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1170,345,666 - 70,448,290 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0170,108,595 - 70,211,414 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0170,819,771 - 70,922,450 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cdc14b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049446,210,303 - 6,348,193 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936487442,814 - 482,299 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_004936487554,611 - 564,782 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936487430,449 - 482,517 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC14B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11025,471,976 - 25,590,022 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21029,550,676 - 29,666,345 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDC14B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112106,520,152 - 106,645,468 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12106,572,015 - 106,633,316 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603894,918,039 - 95,044,036 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdc14b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475317,942,049 - 18,040,542 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475317,941,852 - 18,040,542 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cdc14b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11475,281,881 - 75,360,530 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cdc14b
145 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:489
Count of miRNA genes:257
Interacting mature miRNAs:330
Transcripts:ENSRNOT00000033017
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17121499218Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)17122181410Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122877318Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat

Markers in Region
D17Got231  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr817870,276 - 870,559 (+)Marker Load Pipeline
mRatBN7.217864,552 - 864,835 (-)MAPPERmRatBN7.2
Rnor_6.0171,777,624 - 1,777,906NCBIRnor6.0
Rnor_5.0171,767,180 - 1,767,462UniSTSRnor5.0
RGSC_v3.4176,390,915 - 6,391,197UniSTSRGSC3.4
Celera171,651,890 - 1,652,172UniSTS
Cytogenetic Map17p14UniSTS
D17Got227  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.217864,699 - 864,831 (-)MAPPERmRatBN7.2
Rnor_6.0171,777,628 - 1,777,759NCBIRnor6.0
Rnor_5.0171,767,184 - 1,767,315UniSTSRnor5.0
RGSC_v3.4176,391,062 - 6,391,193UniSTSRGSC3.4
Celera171,651,894 - 1,652,025UniSTS
Cytogenetic Map17p14UniSTS
BE103190  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.217869,293 - 869,464 (-)MAPPERmRatBN7.2
Rnor_6.0171,772,994 - 1,773,164NCBIRnor6.0
Rnor_5.0171,762,550 - 1,762,720UniSTSRnor5.0
RGSC_v3.4176,395,656 - 6,395,826UniSTSRGSC3.4
Celera171,647,261 - 1,647,431UniSTS
RH 3.4 Map1716.0UniSTS
Cytogenetic Map17p14UniSTS
RH139701  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr817912,738 - 913,273 (+)Marker Load Pipeline
mRatBN7.217907,016 - 907,551 (-)MAPPERmRatBN7.2
Rnor_6.0171,729,644 - 1,730,178NCBIRnor6.0
Rnor_5.0171,719,200 - 1,719,734UniSTSRnor5.0
RGSC_v3.4176,433,985 - 6,434,519UniSTSRGSC3.4
Celera171,609,669 - 1,610,203UniSTS
RH 3.4 Map1716.0UniSTS
Cytogenetic Map17p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063276548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005495291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005495292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000033017   ⟹   ENSRNOP00000038515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl17850,438 - 932,817 (+)Ensembl
mRatBN7.2 Ensembl17844,731 - 927,479 (+)Ensembl
Rnor_6.0 Ensembl171,709,703 - 1,797,732 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079742   ⟹   ENSRNOP00000074320
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl17850,390 - 938,968 (+)Ensembl
mRatBN7.2 Ensembl17844,731 - 933,235 (+)Ensembl
Rnor_6.0 Ensembl171,703,943 - 1,797,750 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095758   ⟹   ENSRNOP00000079866
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl17850,390 - 932,817 (+)Ensembl
mRatBN7.2 Ensembl17844,685 - 926,905 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105267   ⟹   ENSRNOP00000094659
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl17850,438 - 971,164 (+)Ensembl
mRatBN7.2 Ensembl17844,731 - 928,032 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114178   ⟹   ENSRNOP00000077998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl17850,438 - 935,596 (+)Ensembl
mRatBN7.2 Ensembl17844,731 - 928,032 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119245   ⟹   ENSRNOP00000097799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl17850,390 - 923,342 (+)Ensembl
mRatBN7.2 Ensembl17844,731 - 932,139 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119773   ⟹   ENSRNOP00000085712
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl17850,438 - 920,062 (+)Ensembl
mRatBN7.2 Ensembl17844,731 - 922,270 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000124350   ⟹   ENSRNOP00000101802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl17850,412 - 935,596 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000131409   ⟹   ENSRNOP00000100855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl17850,390 - 935,596 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000135078   ⟹   ENSRNOP00000111650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl17850,390 - 935,596 (+)Ensembl
RefSeq Acc Id: NM_001108404   ⟹   NP_001101874
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,412 - 935,596 (+)NCBI
mRatBN7.217844,686 - 929,861 (+)NCBI
Rnor_6.0171,709,703 - 1,797,732 (-)NCBI
Rnor_5.0171,699,259 - 1,787,005 (-)NCBI
RGSC_v3.4176,371,204 - 6,454,460 (+)RGD
Celera171,589,728 - 1,671,876 (-)RGD
Sequence:
RefSeq Acc Id: NM_001415672   ⟹   NP_001402601
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,412 - 938,966 (+)NCBI
mRatBN7.217844,686 - 933,231 (+)NCBI
RefSeq Acc Id: NM_001415673   ⟹   NP_001402602
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,412 - 935,596 (+)NCBI
mRatBN7.217844,686 - 929,861 (+)NCBI
RefSeq Acc Id: NM_001415674   ⟹   NP_001402603
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817876,822 - 935,596 (+)NCBI
mRatBN7.217871,098 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095828   ⟹   XP_038951756
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 935,596 (+)NCBI
mRatBN7.217844,881 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095830   ⟹   XP_038951758
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 938,972 (+)NCBI
mRatBN7.217844,881 - 933,237 (+)NCBI
RefSeq Acc Id: XM_039095833   ⟹   XP_038951761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 927,331 (+)NCBI
mRatBN7.217844,881 - 921,609 (+)NCBI
RefSeq Acc Id: XM_039095836   ⟹   XP_038951764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 935,596 (+)NCBI
mRatBN7.217844,881 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095837   ⟹   XP_038951765
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 938,740 (+)NCBI
mRatBN7.217844,881 - 932,865 (+)NCBI
RefSeq Acc Id: XM_039095838   ⟹   XP_038951766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 935,596 (+)NCBI
mRatBN7.217844,881 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095839   ⟹   XP_038951767
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,664 - 935,596 (+)NCBI
mRatBN7.217844,952 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095840   ⟹   XP_038951768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 935,596 (+)NCBI
mRatBN7.217844,881 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095841   ⟹   XP_038951769
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 938,972 (+)NCBI
mRatBN7.217844,881 - 934,787 (+)NCBI
RefSeq Acc Id: XM_039095842   ⟹   XP_038951770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,664 - 935,596 (+)NCBI
mRatBN7.217844,953 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095843   ⟹   XP_038951771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817876,960 - 931,773 (+)NCBI
mRatBN7.217871,243 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095845   ⟹   XP_038951773
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 913,379 (+)NCBI
mRatBN7.217844,881 - 907,730 (+)NCBI
RefSeq Acc Id: XM_063276542   ⟹   XP_063132612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 931,773 (+)NCBI
RefSeq Acc Id: XM_063276543   ⟹   XP_063132613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,664 - 931,773 (+)NCBI
RefSeq Acc Id: XM_063276545   ⟹   XP_063132615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,664 - 931,773 (+)NCBI
RefSeq Acc Id: XM_063276546   ⟹   XP_063132616
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 931,773 (+)NCBI
RefSeq Acc Id: XM_063276547   ⟹   XP_063132617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,664 - 938,972 (+)NCBI
RefSeq Acc Id: XM_063276548   ⟹   XP_063132618
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 938,740 (+)NCBI
RefSeq Acc Id: XR_005495291
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 935,596 (+)NCBI
mRatBN7.217844,881 - 929,861 (+)NCBI
RefSeq Acc Id: XR_005495292
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr817850,272 - 918,621 (+)NCBI
mRatBN7.217844,881 - 912,901 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001101874 (Get FASTA)   NCBI Sequence Viewer  
  NP_001402601 (Get FASTA)   NCBI Sequence Viewer  
  NP_001402602 (Get FASTA)   NCBI Sequence Viewer  
  NP_001402603 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951756 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951758 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951761 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951764 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951765 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951766 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951767 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951768 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951769 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951770 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951771 (Get FASTA)   NCBI Sequence Viewer  
  XP_038951773 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132612 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132613 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132615 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132616 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132617 (Get FASTA)   NCBI Sequence Viewer  
  XP_063132618 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL84431 (Get FASTA)   NCBI Sequence Viewer  
  EDL84432 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000038515
  ENSRNOP00000038515.7
  ENSRNOP00000074320
  ENSRNOP00000074320.3
  ENSRNOP00000077998
  ENSRNOP00000077998.2
  ENSRNOP00000079866
  ENSRNOP00000079866.2
  ENSRNOP00000085712
  ENSRNOP00000085712.2
  ENSRNOP00000094659.2
  ENSRNOP00000097799
  ENSRNOP00000097799.2
  ENSRNOP00000100855.1
  ENSRNOP00000101802
  ENSRNOP00000101802.1
  ENSRNOP00000111650
  ENSRNOP00000111650.1
RefSeq Acc Id: NP_001101874   ⟸   NM_001108404
- Peptide Label: isoform 1
- UniProtKB: F1M567 (UniProtKB/TrEMBL),   A6KQD8 (UniProtKB/TrEMBL),   A0A8I5ZZU6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074320   ⟸   ENSRNOT00000079742
Ensembl Acc Id: ENSRNOP00000038515   ⟸   ENSRNOT00000033017
RefSeq Acc Id: XP_038951769   ⟸   XM_039095841
- Peptide Label: isoform X13
- UniProtKB: A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951758   ⟸   XM_039095830
- Peptide Label: isoform X5
- UniProtKB: A0A0G2K7S1 (UniProtKB/TrEMBL),   A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951765   ⟸   XM_039095837
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951766   ⟸   XM_039095838
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951756   ⟸   XM_039095828
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AK31 (UniProtKB/TrEMBL),   A6KQD7 (UniProtKB/TrEMBL),   A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951764   ⟸   XM_039095836
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951768   ⟸   XM_039095840
- Peptide Label: isoform X11
- UniProtKB: A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951761   ⟸   XM_039095833
- Peptide Label: isoform X6
- UniProtKB: A0A8I5YC46 (UniProtKB/TrEMBL),   A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951773   ⟸   XM_039095845
- Peptide Label: isoform X16
RefSeq Acc Id: XP_038951767   ⟸   XM_039095839
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951770   ⟸   XM_039095842
- Peptide Label: isoform X14
- UniProtKB: A0A8I5ZNF2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951771   ⟸   XM_039095843
- Peptide Label: isoform X15
Ensembl Acc Id: ENSRNOP00000085712   ⟸   ENSRNOT00000119773
Ensembl Acc Id: ENSRNOP00000077998   ⟸   ENSRNOT00000114178
Ensembl Acc Id: ENSRNOP00000097799   ⟸   ENSRNOT00000119245
Ensembl Acc Id: ENSRNOP00000079866   ⟸   ENSRNOT00000095758
Ensembl Acc Id: ENSRNOP00000094659   ⟸   ENSRNOT00000105267
RefSeq Acc Id: NP_001402601   ⟸   NM_001415672
- Peptide Label: isoform 2
- UniProtKB: A0A8I6GMP1 (UniProtKB/TrEMBL),   A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001402602   ⟸   NM_001415673
- Peptide Label: isoform 3
- UniProtKB: A0A8I5YC46 (UniProtKB/TrEMBL),   A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001402603   ⟸   NM_001415674
- Peptide Label: isoform 4
- UniProtKB: A0A8I5ZNF2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132618   ⟸   XM_063276548
- Peptide Label: isoform X13
- UniProtKB: A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132612   ⟸   XM_063276542
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132616   ⟸   XM_063276546
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132617   ⟸   XM_063276547
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063132613   ⟸   XM_063276543
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZZU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132615   ⟸   XM_063276545
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZZU6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101802   ⟸   ENSRNOT00000124350
Ensembl Acc Id: ENSRNOP00000111650   ⟸   ENSRNOT00000135078
Ensembl Acc Id: ENSRNOP00000100855   ⟸   ENSRNOT00000131409
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M567-F1-model_v2 AlphaFold F1M567 1-520 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700269
Promoter ID:EPDNEW_R10786
Type:multiple initiation site
Name:Cdc14b_1
Description:cell division cycle 14B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0171,797,777 - 1,797,837EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311163 AgrOrtholog
BioCyc Gene G2FUF-10541 BioCyc
Ensembl Genes ENSRNOG00000018999 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000033017 ENTREZGENE
  ENSRNOT00000033017.8 UniProtKB/TrEMBL
  ENSRNOT00000079742 ENTREZGENE
  ENSRNOT00000079742.3 UniProtKB/TrEMBL
  ENSRNOT00000095758 ENTREZGENE
  ENSRNOT00000095758.2 UniProtKB/TrEMBL
  ENSRNOT00000105267.2 UniProtKB/TrEMBL
  ENSRNOT00000114178 ENTREZGENE
  ENSRNOT00000114178.2 UniProtKB/TrEMBL
  ENSRNOT00000119245 ENTREZGENE
  ENSRNOT00000119245.2 UniProtKB/TrEMBL
  ENSRNOT00000119773 ENTREZGENE
  ENSRNOT00000119773.2 UniProtKB/TrEMBL
  ENSRNOT00000124350 ENTREZGENE
  ENSRNOT00000124350.1 UniProtKB/TrEMBL
  ENSRNOT00000131409.1 UniProtKB/TrEMBL
  ENSRNOT00000135078 ENTREZGENE
  ENSRNOT00000135078.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/TrEMBL
InterPro CDC14_C UniProtKB/TrEMBL
  DSPn UniProtKB/TrEMBL
  Dual-sp_phosphatase_subgr_cat UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTP UniProtKB/TrEMBL
  Tyr/Dual-specificity_Pase UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
KEGG Report rno:361195 UniProtKB/TrEMBL
NCBI Gene 361195 ENTREZGENE
PANTHER TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE UniProtKB/TrEMBL
Pfam DSPn UniProtKB/TrEMBL
  Tc-R-P UniProtKB/TrEMBL
PhenoGen Cdc14b PhenoGen
PROSITE TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018999 RatGTEx
SMART DSPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/TrEMBL
UniProt A0A0G2K7S1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5YC46 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZNF2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZZU6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AK31 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GMP1 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LEH4_RAT UniProtKB/TrEMBL
  A0ABK0LH56_RAT UniProtKB/TrEMBL
  A0ABK0LL40_RAT UniProtKB/TrEMBL
  A6KQD7 ENTREZGENE, UniProtKB/TrEMBL
  A6KQD8 ENTREZGENE, UniProtKB/TrEMBL
  F1M567 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-23 Cdc14b  cell division cycle 14B  Cdc14b  CDC14 cell division cycle 14 homolog B (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Cdc14b  CDC14 cell division cycle 14 homolog B (S. cerevisiae)   Cdc14b_predicted  CDC14 cell division cycle 14 homolog B (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Cdc14b_predicted  CDC14 cell division cycle 14 homolog B (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED