Gene:	Nck1 ( Rattus norvegicus ) NCK adaptor protein 1
Synonyms:	Nck1_predicted; LOC300955; non-catalytic region of tyrosine kinase adaptor protein 1 (predicted); non-catalytic region of tyrosine kinase adaptor protein 1 ;  (details...)
ArrayIDs:	rc_AA955389_at; 1373940_at;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: NCK1     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Nck1     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Nck1 Rat Celera Assembly 8 100415380 - 100476599     RGSC genome assembly v3.4 8 105346331 - 105361312     Cytogenetic 8 q31     genome assembly 3.1 8 105365785 - 105380767 Mus musculus Nck1 Mouse genome assembly build 36.1 9 100395422 - 100446472     Cytogenetic 9 9 E3.3 Homo sapiens NCK1 human genome assembly 3 138063770 - 138150665     Human genome assembly build 36.2 3 138063763 - 138150658     Cytogenetic 3 q21   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology protein binding,  protein domain specific binding,  kinase activity ...  (details...)
Biological Process	Gene Ontology positive regulation of T cell proliferation,  positive regulation of actin filament polymerization,  lamellipodium assembly ...  (details...)
Cellular Component	Gene Ontology vesicle membrane (details...)
Pathway	Ontology vascular endothelial growth factor signaling pathway (details...)
External Links
Databases	DATABASE ID SOURCE SMART: SH3 IPI SMART: SH2 IPI PROSITE: SH3 IPI PROSITE: SH2 IPI UNIPARC: UPI0000DA30C1 IPI KEGG Report: rno:300955 ENTREZGENE HomoloGene Group ID: 38148 ENTREZGENE Germonline: 1310688 Pfam: SH3_1 IPI Pfam: SH2 IPI KEGG Pathway: 04660 ENTREZGENE KEGG Pathway: 04012 ENTREZGENE InterPro: Cytoplasmic_NCK. IPI InterPro: SH3_domain. IPI InterPro: SH3_region. IPI InterPro: SH2. IPI Ensembl Protein: ENSRNOP00000020330 IPI IPI: IPI00765594 IPI Gene3D-CATH: SH2 IPI Entrez Gene: Nck1 ENTREZGENE PIRSF: Cytoplasmic_NCK IPI IMAGE_CLONE: IMAGE:9034703 IMAGE-MGC_LOAD MGC_CLONE: MGC:189191 IMAGE-MGC_LOAD UniProt: B2RZ33_RAT IPI Ensembl Genes: ENSRNOG00000014917 IPI Superfamily-SCOP: SH3 IPI PRINTS: SH2DOMAIN. IPI PRINTS: SH3DOMAIN. IPI
Sequences	Nucleotide: XM_001066651 Get FASTA Search GEO Profiles Nucleotide: NM_001106851 Get FASTA Search GEO Profiles Nucleotide: XM_001066601 Get FASTA Search GEO Profiles Nucleotide: CH473954 Get FASTA Search GEO Profiles Nucleotide: XM_217246 Get FASTA Search GEO Profiles Nucleotide: BC167009 Get FASTA Search GEO Profiles (View all 6 Nucleotide Accessions) Protein: XP_217246 Get FASTA Protein: NP_001100321 Get FASTA Protein: XP_001066601 Get FASTA Protein: EDL77423 Get FASTA Protein: EDL77422 Get FASTA Protein: AAI67009 Get FASTA Protein: EDL77425 Get FASTA Protein: EDL77424 Get FASTA Protein: XP_001066651 Get FASTA (View all 9 Protein Accessions)
Clusters
References
Curated References	4 references in RGD related to Nck1
Other References	4 other references at PubMed related to Nck1
Database Information
RGD ID	1310688
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 09-SEP-08: Nck1 NCK adaptor protein 1 Nck1 non-catalytic region of tyrosine kinase adaptor protein 1 APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863 30-APR-08: Nck1 non-catalytic region of tyrosine kinase adaptor protein 1 Nck1_predicted non-catalytic region of tyrosine kinase adaptor protein 1 (predicted) APPROVED 'predicted' is removed 2292626 12-JAN-05: Nck1_predicted non-catalytic region of tyrosine kinase adaptor protein 1 (predicted) APPROVED Symbol and Name status set to approved 70820