Col8a1 (collagen type VIII alpha 1 chain) - Rat Genome Database

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Gene: Col8a1 (collagen type VIII alpha 1 chain) Rattus norvegicus
Analyze
Symbol: Col8a1
Name: collagen type VIII alpha 1 chain
RGD ID: 1309361
Description: Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in endodermal cell differentiation. Predicted to act upstream of or within camera-type eye morphogenesis; endothelial cell proliferation; and positive regulation of cell-substrate adhesion. Predicted to be located in extracellular region. Predicted to be part of collagen trimer. Predicted to be active in extracellular matrix. Orthologous to human COL8A1 (collagen type VIII alpha 1 chain); PARTICIPATES IN syndecan signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: collagen alpha-1(VIII) chain; collagen, type VIII, alpha 1; LOC304021; procollagen, type VIII, alpha 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81156,245,998 - 56,378,586 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1156,369,868 - 56,376,229 (+)EnsemblGRCr8
mRatBN7.21142,776,851 - 42,906,432 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1142,777,628 - 42,906,424 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1151,533,937 - 51,662,714 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01144,195,524 - 44,324,293 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01143,324,116 - 43,452,883 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01144,877,690 - 45,006,203 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1144,877,859 - 45,007,891 (+)Ensemblrn6Rnor6.0
Rnor_5.01148,073,158 - 48,201,421 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41143,604,994 - 43,733,870 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1142,573,892 - 42,702,340 (+)NCBICelera
RGSC_v3.11143,785,922 - 43,791,642 (+)NCBI
Cytogenetic Map11q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
3,4-dichloroaniline  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP,ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucosamine  (EXP)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
beta-D-glucosamine  (EXP)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
calcitriol  (ISO)
calcium dichloride  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cobalt dichloride  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diallyl trisulfide  (ISO)
diazinon  (EXP)
dibutyl phthalate  (ISO)
Didecyldimethylammonium  (ISO)
diethyl phthalate  (ISO)
diiodine  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fenamidone  (ISO)
ferric oxide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
furan  (EXP)
geldanamycin  (ISO)
genistein  (ISO)
glycidol  (EXP)
hexadecanoic acid  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
lead diacetate  (EXP)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
mercury dibromide  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methylparaben  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctanoic acid  (EXP)
permethrin  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phthalaldehyde  (ISO)
poly(vinylpyrrolidone)  (EXP)
potassium chromate  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
Rebamipide  (EXP)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triticonazole  (EXP)
troglitazone  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. New Altered Non-Fibrillar Collagens in Human Dilated Cardiomyopathy: Role in the Remodeling Process. Gil-Cayuela C, etal., PLoS One. 2016 Dec 9;11(12):e0168130. doi: 10.1371/journal.pone.0168130. eCollection 2016.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16051690   PMID:18757743   PMID:19168440   PMID:20551380   PMID:23154389   PMID:23376485   PMID:23979707   PMID:24006456   PMID:27068509   PMID:27559042   PMID:30361391  


Genomics

Comparative Map Data
Col8a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81156,245,998 - 56,378,586 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1156,369,868 - 56,376,229 (+)EnsemblGRCr8
mRatBN7.21142,776,851 - 42,906,432 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1142,777,628 - 42,906,424 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1151,533,937 - 51,662,714 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01144,195,524 - 44,324,293 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01143,324,116 - 43,452,883 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01144,877,690 - 45,006,203 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1144,877,859 - 45,007,891 (+)Ensemblrn6Rnor6.0
Rnor_5.01148,073,158 - 48,201,421 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41143,604,994 - 43,733,870 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1142,573,892 - 42,702,340 (+)NCBICelera
RGSC_v3.11143,785,922 - 43,791,642 (+)NCBI
Cytogenetic Map11q12NCBI
COL8A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38399,638,594 - 99,799,217 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl399,638,426 - 99,799,226 (+)Ensemblhg38GRCh38
GRCh37399,357,438 - 99,518,061 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363100,840,144 - 100,997,848 (+)NCBIBuild 36Build 36hg18NCBI36
Build 343100,840,143 - 100,997,848NCBI
Celera397,746,575 - 97,904,287 (+)NCBICelera
Cytogenetic Map3q12.1NCBI
HuRef396,725,773 - 96,884,050 (+)NCBIHuRef
CHM1_1399,320,440 - 99,478,624 (+)NCBICHM1_1
T2T-CHM13v2.03102,343,632 - 102,504,274 (+)NCBIT2T-CHM13v2.0
Col8a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391657,444,619 - 57,575,100 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1657,444,621 - 57,575,100 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381657,624,256 - 57,754,737 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1657,624,258 - 57,754,737 (-)Ensemblmm10GRCm38
MGSCv371657,624,369 - 57,754,850 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361657,548,056 - 57,553,783 (-)NCBIMGSCv36mm8
Celera1657,949,273 - 58,079,512 (-)NCBICelera
Cytogenetic Map16C1.1NCBI
cM Map1634.22NCBI
Col8a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554271,187,550 - 1,335,794 (+)Ensembl
ChiLan1.0NW_0049554271,187,550 - 1,335,794 (+)NCBIChiLan1.0ChiLan1.0
COL8A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2297,584,157 - 97,744,951 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1397,589,413 - 97,749,735 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0396,732,445 - 96,892,726 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13103,416,557 - 103,573,617 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3103,521,159 - 103,573,617 (+)EnsemblpanPan2panpan1.1
COL8A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1336,285,742 - 6,428,172 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl336,285,415 - 6,425,414 (+)EnsemblcanFam3CanFam3.1
Col8a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602150,545,175 - 150,692,760 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366303,443,068 - 3,590,516 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366303,443,085 - 3,590,430 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COL8A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13159,216,144 - 159,374,576 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113159,216,138 - 159,374,718 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213169,086,122 - 169,094,141 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COL8A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12281,094,127 - 81,242,801 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2281,091,493 - 81,242,763 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604185,334,932 - 85,484,882 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Col8a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478912,962,144 - 13,130,492 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Col8a1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1441,717,737 - 41,846,631 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Col8a1
666 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:14
Count of miRNA genes:9
Interacting mature miRNAs:14
Transcripts:ENSRNOT00000060838
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
11528648Bss118Bone structure and strength QTL 1186.6582e-07femur strength trait (VT:0010010)femur ultimate displacement (CMO:0002719)115410798756845449Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 154 83 82 51 28 51 6 278 128 11 133 75 91 31 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000060838   ⟹   ENSRNOP00000057564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1156,369,868 - 56,376,229 (+)Ensembl
mRatBN7.2 Ensembl1142,777,628 - 42,906,424 (+)Ensembl
Rnor_6.0 Ensembl1144,877,859 - 45,007,891 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113782   ⟹   ENSRNOP00000089355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1156,369,868 - 56,375,404 (+)Ensembl
mRatBN7.2 Ensembl1142,777,628 - 42,906,255 (+)Ensembl
RefSeq Acc Id: NM_001107100   ⟹   NP_001100570
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81156,246,782 - 56,375,404 (+)NCBI
mRatBN7.21142,777,628 - 42,906,255 (+)NCBI
Rnor_6.01144,877,918 - 45,006,052 (+)NCBI
Rnor_5.01148,073,158 - 48,201,421 (+)NCBI
RGSC_v3.41143,604,994 - 43,733,870 (+)RGD
Celera1142,573,892 - 42,702,340 (+)RGD
Sequence:
RefSeq Acc Id: XM_006248208   ⟹   XP_006248270
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81156,245,998 - 56,378,586 (+)NCBI
mRatBN7.21142,776,851 - 42,906,432 (+)NCBI
Rnor_6.01144,877,690 - 45,006,203 (+)NCBI
Rnor_5.01148,073,158 - 48,201,421 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598011   ⟹   XP_017453500
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81156,246,021 - 56,378,586 (+)NCBI
mRatBN7.21142,776,915 - 42,906,432 (+)NCBI
Rnor_6.01144,877,690 - 45,006,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039088381   ⟹   XP_038944309
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81156,246,021 - 56,378,586 (+)NCBI
mRatBN7.21142,776,914 - 42,906,432 (+)NCBI
RefSeq Acc Id: XM_039088382   ⟹   XP_038944310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81156,246,021 - 56,378,586 (+)NCBI
mRatBN7.21142,776,914 - 42,906,432 (+)NCBI
RefSeq Acc Id: NP_001100570   ⟸   NM_001107100
- Peptide Label: precursor
- Sequence:
RefSeq Acc Id: XP_006248270   ⟸   XM_006248208
- Peptide Label: isoform X1
- UniProtKB: D4AC70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453500   ⟸   XM_017598011
- Peptide Label: isoform X1
- UniProtKB: D4AC70 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000057564   ⟸   ENSRNOT00000060838
RefSeq Acc Id: XP_038944309   ⟸   XM_039088381
- Peptide Label: isoform X1
- UniProtKB: D4AC70 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944310   ⟸   XM_039088382
- Peptide Label: isoform X1
- UniProtKB: D4AC70 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000089355   ⟸   ENSRNOT00000113782
Protein Domains
C1q

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AC70-F1-model_v2 AlphaFold D4AC70 1-744 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698106
Promoter ID:EPDNEW_R8631
Type:multiple initiation site
Name:Col8a1_1
Description:collagen type VIII alpha 1 chain
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01144,877,920 - 44,877,980EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309361 AgrOrtholog
BioCyc Gene G2FUF-21547 BioCyc
Ensembl Genes ENSRNOG00000039668 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000060838.6 UniProtKB/TrEMBL
  ENSRNOT00000113782 ENTREZGENE
  ENSRNOT00000113782.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.40 UniProtKB/TrEMBL
InterPro C1q UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
  Collagen/C1q_domain UniProtKB/TrEMBL
  Tumour_necrosis_fac-like UniProtKB/TrEMBL
KEGG Report rno:304021 UniProtKB/TrEMBL
NCBI Gene 304021 ENTREZGENE
PANTHER COLLAGEN ALPHA-1(VIII) CHAIN UniProtKB/TrEMBL
  EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER UniProtKB/TrEMBL
Pfam C1q UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
PhenoGen Col8a1 PhenoGen
PRINTS COMPLEMNTC1Q UniProtKB/TrEMBL
PROSITE C1Q UniProtKB/TrEMBL
RatGTEx ENSRNOG00000039668 RatGTEx
SMART C1Q UniProtKB/TrEMBL
Superfamily-SCOP TNF_like UniProtKB/TrEMBL
UniProt A0A8I6AA24_RAT UniProtKB/TrEMBL
  A6IQM2_RAT UniProtKB/TrEMBL
  D4AC70 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-27 Col8a1  collagen type VIII alpha 1 chain  Col8a1  collagen, type VIII, alpha 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-25 Col8a1  collagen, type VIII, alpha 1  Col8a1_predicted  procollagen, type VIII, alpha 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Col8a1_predicted  procollagen, type VIII, alpha 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED