Mapk11 (mitogen-activated protein kinase 11) - Rat Genome Database

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Gene: Mapk11 (mitogen-activated protein kinase 11) Rattus norvegicus
Analyze
Symbol: Mapk11
Name: mitogen-activated protein kinase 11
RGD ID: 1309340
Description: Enables ATP binding activity and MAP kinase activity. Predicted to be involved in several processes, including MAPK cascade; cellular response to UV-B; and positive regulation of interleukin-12 production. Predicted to act upstream of or within negative regulation of cardiac muscle cell proliferation. Predicted to be active in cytosol and nucleus. Orthologous to human MAPK11 (mitogen-activated protein kinase 11); PARTICIPATES IN adenosine signaling pathway; eicosanoid signaling pathway; FasL mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC362982; LOC689314; MGC187942; p38beta; similar to mitogen-activated protein kinase 11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87122,098,120 - 122,105,023 (-)NCBIGRCr8
mRatBN7.27120,218,471 - 120,225,488 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7120,218,478 - 120,225,395 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7121,970,470 - 121,976,406 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07124,196,633 - 124,202,569 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07124,159,641 - 124,165,578 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07130,121,678 - 130,129,199 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,121,687 - 130,128,604 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07129,808,443 - 129,814,378 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47127,444,055 - 127,449,990 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7116,693,340 - 116,699,275 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-nitrophenol  (ISO)
acrolein  (ISO)
acrylamide  (EXP,ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (EXP)
disodium selenite  (ISO)
elemental selenium  (ISO)
ellagic acid  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
flurbiprofen  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
hemin  (ISO)
hexadecanoic acid  (EXP)
ibuprofen  (ISO)
lead diacetate  (EXP,ISO)
manganese(II) chloride  (EXP)
methamphetamine  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
microcystin-LR  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nicotine  (ISO)
obeticholic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
PCB138  (EXP)
pentanal  (ISO)
pyrazoles  (ISO)
pyrimidines  (ISO)
quercetin  (ISO)
reactive oxygen species  (EXP)
resveratrol  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 203580  (EXP,ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
streptozocin  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
Urolithin A  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
xanthohumol  (ISO)

References

References - curated
# Reference Title Reference Citation
1. p38 MAP-kinases pathway regulation, function and role in human diseases. Cuenda A and Rousseau S, Biochim Biophys Acta. 2007 Aug;1773(8):1358-75. Epub 2007 Mar 24.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Melatonin arrests peroxynitrite-induced tau hyperphosphorylation and the overactivation of protein kinases in rat brain. Yin J, etal., J Pineal Res. 2006 Sep;41(2):124-9.
Additional References at PubMed
PMID:8663524   PMID:10330143   PMID:12477932   PMID:16364914   PMID:17069850   PMID:18515110   PMID:20134354   PMID:21354263   PMID:21768366   PMID:21777656   PMID:22157753   PMID:23483889  
PMID:24465521   PMID:25754930   PMID:34814904  


Genomics

Comparative Map Data
Mapk11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87122,098,120 - 122,105,023 (-)NCBIGRCr8
mRatBN7.27120,218,471 - 120,225,488 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7120,218,478 - 120,225,395 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7121,970,470 - 121,976,406 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07124,196,633 - 124,202,569 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07124,159,641 - 124,165,578 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07130,121,678 - 130,129,199 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,121,687 - 130,128,604 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07129,808,443 - 129,814,378 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47127,444,055 - 127,449,990 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7116,693,340 - 116,699,275 (-)NCBICelera
Cytogenetic Map7q34NCBI
MAPK11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382250,263,713 - 50,270,380 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2250,263,713 - 50,270,767 (-)EnsemblGRCh38hg38GRCh38
GRCh372250,702,142 - 50,708,809 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362249,044,269 - 49,050,906 (-)NCBINCBI36Build 36hg18NCBI36
Build 342249,004,599 - 49,011,236NCBI
Celera2234,577,045 - 34,583,684 (-)NCBICelera
Cytogenetic Map22q13.33NCBI
HuRef2233,599,558 - 33,605,992 (-)NCBIHuRef
CHM1_12250,660,928 - 50,667,565 (-)NCBICHM1_1
T2T-CHM13v2.02250,770,716 - 50,777,383 (-)NCBIT2T-CHM13v2.0
Mapk11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391589,026,685 - 89,033,809 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1589,026,689 - 89,033,831 (-)EnsemblGRCm39 Ensembl
GRCm381589,142,482 - 89,149,606 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1589,142,486 - 89,149,628 (-)EnsemblGRCm38mm10GRCm38
MGSCv371588,972,912 - 88,980,036 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361588,970,248 - 88,977,323 (-)NCBIMGSCv36mm8
Celera1591,271,050 - 91,278,706 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1544.66NCBI
Mapk11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541333,286,390 - 33,294,227 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541333,287,860 - 33,293,948 (-)NCBIChiLan1.0ChiLan1.0
MAPK11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22360,169,844 - 60,176,642 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12262,856,001 - 62,862,799 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02230,492,664 - 30,499,456 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12249,491,462 - 49,495,766 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2249,492,693 - 49,495,732 (-)Ensemblpanpan1.1panPan2
MAPK11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11016,977,133 - 16,984,764 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1016,955,828 - 16,963,117 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01017,704,608 - 17,711,910 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11017,428,715 - 17,435,996 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01017,752,004 - 17,759,275 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01017,884,182 - 17,891,467 (+)NCBIUU_Cfam_GSD_1.0
Mapk11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945545,727 - 549,861 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936629545,755 - 549,837 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936629542,143 - 549,861 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAPK11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5421,798 - 428,101 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.15420,848 - 428,103 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MAPK11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11932,754,261 - 32,760,859 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1932,752,546 - 32,760,798 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604592,593,845 - 92,600,476 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mapk11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624752502,350 - 508,449 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624752502,411 - 508,452 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mapk11
18 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:198
Count of miRNA genes:129
Interacting mature miRNAs:161
Transcripts:ENSRNOT00000009325
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
1582240Sffal1Serum free fatty acids level QTL 13.40.0021blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)7116677010124049952Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)7116677189127103496Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

Markers in Region
RH137764  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27120,218,528 - 120,218,715 (+)MAPPERmRatBN7.2
Rnor_6.07130,121,738 - 130,121,924NCBIRnor6.0
Rnor_5.07129,807,527 - 129,807,713UniSTSRnor5.0
RGSC_v3.47127,443,139 - 127,443,325UniSTSRGSC3.4
Celera7116,692,424 - 116,692,610UniSTS
RH 3.4 Map7958.3UniSTS
Cytogenetic Map7q34UniSTS
Mapk11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27120,218,618 - 120,219,676 (+)MAPPERmRatBN7.2
Rnor_6.07130,121,828 - 130,122,885NCBIRnor6.0
Rnor_5.07129,807,617 - 129,808,674UniSTSRnor5.0
RGSC_v3.47127,443,229 - 127,444,286UniSTSRGSC3.4
Celera7116,692,514 - 116,693,571UniSTS
Cytogenetic Map7q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 74 1 1
Low 3 43 57 41 19 41 5 8 35 34 10 5
Below cutoff 3 3 6 3

Sequence


RefSeq Acc Id: ENSRNOT00000009325   ⟹   ENSRNOP00000009325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7120,218,478 - 120,225,395 (-)Ensembl
Rnor_6.0 Ensembl7130,121,687 - 130,128,604 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079777   ⟹   ENSRNOP00000075602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7120,219,445 - 120,225,380 (-)Ensembl
Rnor_6.0 Ensembl7130,122,654 - 130,128,589 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104992   ⟹   ENSRNOP00000080828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7120,218,478 - 120,225,309 (-)Ensembl
RefSeq Acc Id: NM_001109532   ⟹   NP_001103002
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,099,088 - 122,105,023 (-)NCBI
mRatBN7.27120,219,445 - 120,225,380 (-)NCBI
Rnor_6.07130,122,654 - 130,128,589 (-)NCBI
Rnor_5.07129,808,443 - 129,814,378 (-)NCBI
RGSC_v3.47127,444,055 - 127,449,990 (-)RGD
Celera7116,693,340 - 116,699,275 (-)RGD
Sequence:
RefSeq Acc Id: XM_017595119   ⟹   XP_017450608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,098,120 - 122,104,969 (-)NCBI
mRatBN7.27120,218,471 - 120,225,475 (-)NCBI
Rnor_6.07130,121,678 - 130,128,641 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079918   ⟹   XP_038935846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,100,605 - 122,104,969 (-)NCBI
mRatBN7.27120,220,962 - 120,225,487 (-)NCBI
RefSeq Acc Id: XM_039079919   ⟹   XP_038935847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,100,877 - 122,104,969 (-)NCBI
mRatBN7.27120,221,234 - 120,225,488 (-)NCBI
RefSeq Acc Id: XM_063264275   ⟹   XP_063120345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,098,120 - 122,103,781 (-)NCBI
RefSeq Acc Id: NP_001103002   ⟸   NM_001109532
- UniProtKB: A0A0G2KB06 (UniProtKB/TrEMBL),   A0A8I6G769 (UniProtKB/TrEMBL),   A6K7K4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450608   ⟸   XM_017595119
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G769 (UniProtKB/TrEMBL),   B1WC76 (UniProtKB/TrEMBL),   D4A3U7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075602   ⟸   ENSRNOT00000079777
RefSeq Acc Id: ENSRNOP00000009325   ⟸   ENSRNOT00000009325
RefSeq Acc Id: XP_038935846   ⟸   XM_039079918
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038935847   ⟸   XM_039079919
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000080828   ⟸   ENSRNOT00000104992
RefSeq Acc Id: XP_063120345   ⟸   XM_063264275
- Peptide Label: isoform X2
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3U7-F1-model_v2 AlphaFold D4A3U7 1-371 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309340 AgrOrtholog
BioCyc Gene G2FUF-32460 BioCyc
Ensembl Genes ENSRNOG00000006984 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009325.7 UniProtKB/TrEMBL
  ENSRNOT00000079777 ENTREZGENE
  ENSRNOT00000079777.2 UniProtKB/TrEMBL
  ENSRNOT00000104992.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom UniProtKB/TrEMBL
  MAP_kinase_CS UniProtKB/TrEMBL
  MAPK_p38 UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
KEGG Report rno:689314 UniProtKB/TrEMBL
NCBI Gene Mapk11 ENTREZGENE
PANTHER MITOGEN-ACTIVATED PROTEIN KINASE UniProtKB/TrEMBL
  MITOGEN-ACTIVATED PROTEIN KINASE 11 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Mapk11 PhenoGen
PRINTS P38MAPKINASE UniProtKB/TrEMBL
PROSITE MAPK UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006984 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A0G2KB06 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G769 ENTREZGENE, UniProtKB/TrEMBL
  A6K7K4 ENTREZGENE, UniProtKB/TrEMBL
  B1WC76 ENTREZGENE
  D4A3U7 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B1WC76 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-22 Mapk11  mitogen-activated protein kinase 11   LOC689314  similar to mitogen-activated protein kinase 11  Data merged from RGD:1593550 737654 APPROVED
2008-04-30 Mapk11  mitogen-activated protein kinase 11   Mapk11_predicted  mitogen-activated protein kinase 11 (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-20 LOC689314  similar to mitogen-activated protein kinase 11      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Mapk11_predicted  mitogen-activated protein kinase 11 (predicted)      Symbol and Name status set to approved 70820 APPROVED