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Gene: Pop1 (POP1 ribonuclease P/MRP subunit) Rattus norvegicus

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Symbol:

Pop1

Name:

POP1 ribonuclease P/MRP subunit (Ensembl:POP1 homolog, ribonuclease P/MRP subunit)

RGD ID:

1308609

Description:

Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal and tRNA decay. Predicted to be located in nucleolus. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Human ortholog(s) of this gene implicated in anauxetic dysplasia 2. Orthologous to human POP1 (POP1 homolog, ribonuclease P/MRP subunit); PARTICIPATES IN tRNA maturation pathway; ribosome biogenesis pathway; RNA transport pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC315045; POP1 homolog, ribonuclease P/MRP subunit; processing of precursor 1; processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae); processing of precursor 1, ribonuclease P/MRP subunit; processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae); ribonucleases P/MRP protein subunit POP1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	POP1 (POP1 ribonuclease P/MRP subunit)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Pop1 (processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pop1 (POP1 ribonuclease P/MRP subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	POP1 (POP1 ribonuclease P/MRP subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	POP1 (POP1 homolog, ribonuclease P/MRP subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pop1 (POP1 ribonuclease P/MRP subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	POP1 (POP1 homolog, ribonuclease P/MRP subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	POP1 (POP1 ribonuclease P/MRP subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pop1 (POP1 ribonuclease P/MRP subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pop1 (POP1 ribonuclease P/MRP subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	POP1 (POP1 ribonuclease P/MRP subunit)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pop1 (processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pop1 (POP1 homolog, ribonuclease P/MRP subunit)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pop1 (POP1 homolog, ribonuclease P/MRP subunit)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C05D11.9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	POP1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	l(1)G0045	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pop1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	67,590,502 - 67,618,187 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	67,590,522 - 67,618,293 (+)	Ensembl				GRCr8
mRatBN7.2	7	65,705,348 - 65,733,143 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	65,705,368 - 65,733,141 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	67,594,571 - 67,622,250 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	69,796,304 - 69,823,946 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	69,661,718 - 69,689,297 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	73,270,403 - 73,298,209 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	73,270,455 - 73,298,239 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	73,436,473 - 73,473,185 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	69,944,414 - 69,979,794 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	62,806,384 - 62,834,025 (+)	NCBI		Celera
RGSC_v3.1	7	69,965,163 - 70,000,525 (+)	NCBI
Cytogenetic Map	7	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

anauxetic dysplasia 1 (ISO)

anauxetic dysplasia 2 (ISO)

Desbuquois dysplasia (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-alpha-phellandrene (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-phellandrene (ISO)

alpha-pinene (ISO)

amphetamine (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

caffeine (ISO)

carbon nanotube (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

cobalt dichloride (EXP)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

DDE (ISO)

dexamethasone (ISO)

Dibutyl phosphate (ISO)

dorsomorphin (ISO)

enzyme inhibitor (ISO)

flutamide (EXP)

FR900359 (ISO)

furan (EXP)

gallic acid (ISO)

gentamycin (EXP)

glyphosate (EXP)

GSK-J4 (ISO)

hydrogen peroxide (ISO)

indometacin (ISO)

ivermectin (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methapyrilene (ISO)

nickel atom (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

potassium chromate (ISO)

potassium dichromate (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

thapsigargin (ISO)

thimerosal (ISO)

thioacetamide (EXP)

thiram (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

tRNA 5'-leader removal (IEA,ISO)

tRNA decay (IEA,ISO)

tRNA processing (IBA,IEA)

Cellular Component

multimeric ribonuclease P complex (IEA,ISO)

nucleolar ribonuclease P complex (IBA,IEA,ISO)

nucleolus (IEA,ISO)

nucleus (IEA)

ribonuclease MRP complex (IBA,IEA,ISO)

Molecular Function

protein binding (ISO)

ribonuclease P activity (IEA,ISO)

ribonuclease P RNA binding (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ribosome biogenesis pathway (IEA)

RNA transport pathway (IEA)

tRNA maturation pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Unexpected diversity of RNase P, an ancient tRNA processing enzyme: challenges and prospects.	Lai LB, etal., FEBS Lett. 2010 Jan 21;584(2):287-96. doi: 10.1016/j.febslet.2009.11.048. Epub .
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:8918471	PMID:16723659	PMID:22658674	PMID:22664934	PMID:30454648

Genomics

Comparative Map Data

Pop1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	67,590,502 - 67,618,187 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	67,590,522 - 67,618,293 (+)	Ensembl				GRCr8
mRatBN7.2	7	65,705,348 - 65,733,143 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	65,705,368 - 65,733,141 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	67,594,571 - 67,622,250 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	69,796,304 - 69,823,946 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	69,661,718 - 69,689,297 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	73,270,403 - 73,298,209 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	73,270,455 - 73,298,239 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	73,436,473 - 73,473,185 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	69,944,414 - 69,979,794 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	62,806,384 - 62,834,025 (+)	NCBI		Celera
RGSC_v3.1	7	69,965,163 - 70,000,525 (+)	NCBI
Cytogenetic Map	7	q22	NCBI

POP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	98,117,293 - 98,159,835 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	98,117,293 - 98,159,835 (+)	Ensembl			hg38	GRCh38
GRCh37	8	99,129,521 - 99,172,063 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	99,199,244 - 99,239,816 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	8	99,199,243 - 99,239,814	NCBI
Celera	8	95,315,383 - 95,357,929 (+)	NCBI		Celera
Cytogenetic Map	8	q22.2	NCBI
HuRef	8	94,333,090 - 94,375,569 (+)	NCBI		HuRef
CHM1_1	8	99,170,273 - 99,212,813 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	99,242,783 - 99,285,304 (+)	NCBI		T2T-CHM13v2.0

Pop1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	34,495,457 - 34,530,799 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	34,495,450 - 34,530,794 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	34,495,311 - 34,530,653 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	34,495,304 - 34,530,648 (+)	Ensembl			mm10	GRCm38
MGSCv37	15	34,425,066 - 34,460,408 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	34,439,912 - 34,475,237 (+)	NCBI		MGSCv36	mm8
Celera	15	35,123,159 - 35,157,920 (+)	NCBI		Celera
Cytogenetic Map	15	B3.1	NCBI
cM Map	15	14.34	NCBI

Pop1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955417	13,823,057 - 13,856,448 (+)	Ensembl
ChiLan1.0	NW_004955417	13,823,027 - 13,856,448 (+)	NCBI	ChiLan1.0	ChiLan1.0

POP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	115,458,813 - 115,501,190 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	91,000,256 - 91,042,640 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	94,754,028 - 94,796,374 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	96,938,574 - 96,980,896 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	96,944,588 - 96,979,328 (+)	Ensembl			panPan2	panpan1.1

POP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	361,095 - 398,214 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	361,157 - 396,628 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	354,500 - 400,369 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	509,663 - 555,581 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	509,734 - 546,040 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	353,061 - 398,925 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	461,025 - 506,891 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	467,078 - 512,927 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pop1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	37,250,693 - 37,284,328 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	44,676,776 - 44,710,716 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	44,676,798 - 44,710,397 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	38,607,708 - 38,656,151 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	38,608,536 - 38,656,204 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	41,668,276 - 41,807,928 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

POP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	93,031,600 - 93,074,700 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	93,043,277 - 93,074,818 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666039	47,664,062 - 47,707,173 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pop1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624763	5,269,847 - 5,300,723 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624763	5,264,003 - 5,299,000 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pop1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	208,197,655 - 208,224,927 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pop1
109 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	14
Count of miRNA genes:	14
Interacting mature miRNAs:	14
Transcripts:	ENSRNOT00000007190
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411569	Bw137	Body weight QTL 137		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	23807606	68807606	Rat
10053722	Scort27	Serum corticosterone level QTL 27	2.41	0.0083	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	45113903	90113903	Rat
1549840	Bss5	Bone structure and strength QTL 5	9.8		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	26638057	71638057	Rat
1300127	Srn1	Serum renin concentration QTL 1	3.87		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	7	24179478	86817926	Rat
10059605	Kidm47	Kidney mass QTL 47	2.91	0.05	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	49137999	67614020	Rat
1357336	Gluco6	Glucose level QTL 6	3.4		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	7	51700643	96700643	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	31770293	110435881	Rat
1298525	Cm1	Cardiac mass QTL 1	2.7		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	7	56625161	101625161	Rat
631513	Scl7	Serum cholesterol level QTL 7	4.1		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	39845902	84845902	Rat
10755453	Coatc12	Coat color QTL 12		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	32998702	77998702	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
7411605	Foco14	Food consumption QTL 14	24.1	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	36178764	81178764	Rat
1300151	Bp181	Blood pressure QTL 181	3.36		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	7	55498584	105834451	Rat
1559283	Emca4	Estrogen-induced mammary cancer QTL 4	3.7		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	7	63889858	108889858	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	10112916	99900612	Rat
738030	Anxrr8	Anxiety related response QTL 8	4.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	48475049	93475049	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	1	104117804	Rat
631534	Lnnr1	Liver neoplastic nodule remodeling QTL 1	3.85	0.001	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	7	36178764	81178764	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	49682832	115766396	Rat
1298528	Bp169	Blood pressure QTL 169		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	62963207	107963207	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	21541977	86817926	Rat
1576303	Ept7	Estrogen-induced pituitary tumorigenesis QTL 7	3.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	7	63889858	108889858	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	49682832	115766396	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	49682832	115766396	Rat
2303582	Gluco53	Glucose level QTL 53	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	7	48603087	93603087	Rat
61439	Cia8	Collagen induced arthritis QTL 8	5.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	7	27182914	72182914	Rat

Markers in Region

D7Rat165

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	7	67,613,787 - 67,614,020 (+)	Marker Load Pipeline
mRatBN7.2	7	65,728,634 - 65,728,867 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	73,293,702 - 73,293,934	NCBI	Rnor6.0
Rnor_5.0	7	73,468,678 - 73,468,910	UniSTS	Rnor5.0
RGSC_v3.4	7	69,975,398 - 69,975,631	RGD	RGSC3.4
RGSC_v3.4	7	69,975,399 - 69,975,631	UniSTS	RGSC3.4
Celera	7	62,829,630 - 62,829,862	UniSTS
RGSC_v3.1	7	69,995,901 - 69,996,450	RGD
FHH x ACI Map	7	34.52	UniSTS
FHH x ACI Map	7	34.52	RGD
Cytogenetic Map	7	q22	UniSTS

BE105841

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	65,732,794 - 65,732,978 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	73,297,861 - 73,298,044	NCBI	Rnor6.0
Rnor_5.0	7	73,472,837 - 73,473,020	UniSTS	Rnor5.0
RGSC_v3.4	7	69,979,558 - 69,979,741	UniSTS	RGSC3.4
Celera	7	62,833,789 - 62,833,972	UniSTS
Cytogenetic Map	7	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001130550	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001434609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241543	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC115401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223904	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000007190 ⟹ ENSRNOP00000007190

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	67,590,541 - 67,618,183 (+)	Ensembl
mRatBN7.2 Ensembl	7	65,705,387 - 65,733,031 (+)	Ensembl
Rnor_6.0 Ensembl	7	73,270,455 - 73,298,097 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000077730 ⟹ ENSRNOP00000073143

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	67,590,522 - 67,618,293 (+)	Ensembl
mRatBN7.2 Ensembl	7	65,705,368 - 65,733,141 (+)	Ensembl
Rnor_6.0 Ensembl	7	73,273,985 - 73,298,239 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000148795 ⟹ ENSRNOP00000112185

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	67,594,086 - 67,618,293 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000169474 ⟹ ENSRNOP00000101658

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	67,590,827 - 67,618,293 (+)	Ensembl

RefSeq Acc Id:

NM_001130550 ⟹ NP_001124022

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	67,590,541 - 67,618,183 (+)	NCBI
mRatBN7.2	7	65,705,387 - 65,733,031 (+)	NCBI
Rnor_6.0	7	73,270,455 - 73,298,097 (+)	NCBI
Rnor_5.0	7	73,436,473 - 73,473,185 (+)	NCBI
RGSC_v3.4	7	69,944,414 - 69,979,794 (+)	RGD
Celera	7	62,806,384 - 62,834,025 (+)	RGD

Sequence:

show sequence

GCTCAGTTCACTTGCTCGCCCGCCGTGGTGGGATCTTCCAGGGGTTTCAGAACCTTGTCACTGA
CCGGCGAAGCCCTCGGAGCATTTGGCAGAAATGTCTAACGCAAAGGAGAGAAAACATGCTAAGA
AAATGAGAAGCCAGCCCAGTAATGTGACTCTGTCCTCCGGCTTTGTGACTGAGAGAGATGGAAA
GCGCCATTTTGGGGGGAAACCTTCCCAATCTCAGAAACAAGAGCTTCATTCTGGAACCTCACGG
CAGTGGCAGATCAAGATGAGCCCCCACTTACTTCCTGAGTCTGATGCGAATGAGCAGACTTCCT
CCAAAACCATGTTTAAGAAAAAGGGAGGCTGGAAAGCAGGTCCTGAGGGCACTTCTCAGGAGAT
CCCCAAATATATAACCGCTTCTACCTTTGCTCAAGCACGAGCTGCCGAGATCAGTGCCATGTTA
AAAGCTGTGACCCAGAAGTCCTCCAATTCCCTGGTTTTCCAGACTCTTCCACGGCACATGCGGC
GAAGAGCCATGAGCCACAACGTCAAACGCCTTCCTAGAAGGTTGCAGGAGATGGCCAAAAAGGA
GGCTGAGAAAGCCGCTCATCAGAAAAAAGAACATTCGAAAAATAAATGCCACAAAGCCCGAAGA
TGTCACATAAACCGGACCCTGGAGTTTAACCGCAGACAACAGAAGAATATATGGTTAGAGACTC
ATATCTGGCATGCCAAACGGTTTCATATGGTGAAGAGGTGGGGTTACTGTCTCGGGGAGAGGCC
CACGGCCAAGAGCCACCGAGCCTGCTATCGAGCTATGACAGACCTCTGCCTCCTACAGGATTTA
TCATATTACTGTTGTTTGGAGTTGAAGGGCAAAGAGGAAGAAATACTGAAGGCACTTTCTCAAA
TGTGCAGCATAGACACAGGACTGACTTTTGCTGCAGTTCACTGCTTGTCTGGGAAGCGGCAAGG
GAGCCTCATGCTTTACCGGGCAAATAAGTATCCCAGAGACATGCTTGGGCCGGTTACCTTCATC
TGGAAGTCTAGGGAGACCCCAGGGGACGCCTCTGAGGAAAGGCAGCTGTGGATCTGGCTTCACC
CAACTCTTAAACTGGCTGTCCTAGAGGAAATAAAAACAACGTGCCAGTGTTCAGAACCCGTCAA
GCCAAGTGTCTGTGTGCCTGCCCCACTCCTGACACCAGCCCAGGAAGACATTCAGGCAGGACTA
GCTGATGACAAAATCGGCAAGAAAAGAAAAAGGAGAGATGATGGGGAAAATGCTAGACGAGCGA
AGAAGACCATTGGTGACGGGACAGGAGATCCCTGCCAGCCACGGTCGTGGCTCTCTCCCACTAC
AGGGATCGTAGTCAGTGACTTGACCATGGAGATGAACAGGTTCCGGCTGGTCGGACCTCTTTCG
CACTGTATCCTGACCTCAGCACTGAGGGCTGCTCCTGTACACAGAGGTGAGGAGGATGCAGAGG
AGACACCGCATGGCTGGTGGACTGACACGTGCAGGAGTCCTCATGGCCTTTCTCTTCACCAGAG
ACAAGAAGCAGTGTTTCAGTTGTTGGGAGGGATATCGTCACCGGCAGAAATTCCAGCAGGTACT
ATTCTGGGATTGACAGTCAGGGACCCGAGAGTAAATTTGCCTCCACAGCGGTGCAGAGCTTTGC
CTGATCCAGAACGATACCACGTTTCAGAATTTATCTGTGAGGAAGGGATGTGCACCAGCAGCTG
GTCTTGTGCTCATTGGAAGCCTCTGTCTGACCATACAGATGATCCAGACAATGAGCAAGTTAAG
CAGCTGCTTCTGGAGGGTGTGCCTGTGGAGTGTGCACACAGCTTCATCTGGAACCAGGATATCT
GCCAGAGCGTTACAGAGAATAAAATCGTGGACCAGGATTTAAACCGCATGAGAAGCGAATTGCT
GGTGCCCGGATCACAGCTTGTTTTAGGGGCTCGTGAATCCAAGATACCTATACTTCTGATTCAG
CAGCCGGGAAAAGTGACTGGCGAAGACCGACTGGGCTGGGGCAGTGGCTGGGACATCCTCCTTC
CCAAGGGCTGGGGCATGGCCTTTTGGATTCCATTTATCTACCGAGGTGCAAGGGTTGGTGGATT
AAAAGAGGCTGCAGTACACTCTCAGTACAAACGGTCACCTAATGTCCCAGGCGACTTCCCAGAC
TGTCGTGCTGGCGTTCTCTTCGCTGAAGACCAAGCTAAGGACCTTCTAGAGAAGTACCAAAGAC
GCCCCCCTGCTAAAAGGCCCAACTATGTTAAGCTTGGCACACTGGCTCCTTTCTGTTGTCCCTG
GGAACAGCTGACTCGGGACTGGGAGTCCAGGATTCAGACCCAAGAAGCAGCTGTTATAGATTCA
GTGCCTGGTGCTCAAGAGACTGACCCAAGAAGGCTTGGAGTGCCTTGTGTCCCCAAAGAGACCT
GCCAGCTATCGAATGAGGCAAGCATAGCTGAAAACCAACCTAGGAAGCCGGAAGTTACAGGCTG
TCAAGCTCAGGCGGGGACTGAGGTGGCCCTGGAACAGAATGCCAGTGAGGACCACGCAGCTGCC
ACAGGTAGCCAGCTCTGTGTTGTTCGGAGTAGGAAACTACTGAAGCAACTCTCTTCCTGGTGTG
GGCCCAGTTCTGAGGTCAGGAGGGCTCCCTGCAGAGGCCAGCAAGAACTGACTAGAAAGGCTTG
CCTGTCCATTCTGGCTGATTTCCCCAGAGCGCTGGTGTGGGTCAGCTTGTCCCTGCTCAAGAAG
GGCAGCCCAGAGCCACACACCATGATCTGTGTCCCATCCAAGGAGGACTTGTTCCAGCTCAGTC
AGGATCAGTGTTACCATGGACCCTGCGAATCCAGACACAGCGACCCATTTAAAAGCTTGATTCT
GAAGGAGAAAGAAAAGAAGAAGAAGGAGAAGAGGCAGGATGGGGAGCAGGGGGCCTCCAAGGGC
CAGGCAGCAGGGGCACCTACAGCTGGGCAGGAGGCTCGGATTCAGGGGCTGTGGTCAGGCCCCC
TTCCGGGGCTGACTTCACACTGCTCCAGGCCCCTCCTGGGCTTCGTGACACATGGAGATTTCTC
TATGGCTGTTGGCTGTGGAGAAGCCTTAGGGTTTGTTAGTGTAACAGGCTTGCTGGAAATGTTG
TCCAGCCAGTCAGCAGCCATGAGGGGCCTGGTCCTGCTGCGGCCTCCGACCTCGCTGCAATACC
GGTTTGCTAGAGTTACCATTGAGGTGTGAATTCGAGTTTACACCCTTAACCTAGGTCCTAACTA
TTTTTGTCAAATTCCAAAGAGAGTCCTGGCCGTCTCGGTCACCTGAATTAAAATACAATGTGGA
ACTGCTTGGAAAACAAGAATTAAAATTATATAATTATGTGG

hide sequence

RefSeq Acc Id:

XM_006241543 ⟹ XP_006241605

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	67,590,502 - 67,618,187 (+)	NCBI
mRatBN7.2	7	65,705,348 - 65,733,143 (+)	NCBI
Rnor_6.0	7	73,270,403 - 73,298,209 (+)	NCBI
Rnor_5.0	7	73,436,473 - 73,473,185 (+)	NCBI

Sequence:

show sequence

TTCATATGTGACTCCACGACACGTGGAGGAAGAAGCCGTGCTGCTCATGCGCGCTCAGTTCACT
TGCTCGCCCGCCGTGGTGGGATCTTCCAGGGGTTTCAGAACCTTGTCACTGACCGGCGAAGCCC
TCGGAGCATTTGGCAGAAATGTCTAACGCAAAGGAGAGAAAACATGCTAAGAAAATGAGAAGCC
AGCCCAGTAATGTGACTCTGTCCTCCGGCTTTGTGACTGAGAGAGATGGAAAGCGCCATTTTGG
GGGGAAACCTTCCCAATCTCAGAAACAAGAGCTTCATTCTGGAACCTCACGGCAGTGGCAGATC
AAGATGAGCCCCCACTTACTTCCTGAGTCTGATGCGAATGAGCAGACTTCCTCCAAAACCATGT
TTAAGAAAAAGGGAGGCTGGAAAGCAGGTCCTGAGGGCACTTCTCAGGAGATCCCCAAATATAT
AACCGCTTCTACCTTTGCTCAAGCACGAGCTGCCGAGATCAGTGCCATGTTAAAAGCTGTGACC
CAGAAGTCCTCCAATTCCCTGGTTTTCCAGACTCTTCCACGGCACATGCGGCGAAGAGCCATGA
GCCACAACGTCAAACGCCTTCCTAGAAGGTTGCAGGAGATGGCCAAAAAGGAGGCTGAGAAAGC
CGCTCATCAGAAAAAAGAACATTCGAAAAATAAATGCCACAAAGCCCGAAGATGTCACATAAAC
CGGACCCTGGAGTTTAACCGCAGACAACAGAAGAATATATGGTTAGAGACTCATATCTGGCATG
CCAAACGGTTTCATATGGTGAAGAGGTGGGGTTACTGTCTCGGGGAGAGGCCCACGGCCAAGAG
CCACCGAGCCTGCTATCGAGCTATGACAGACCTCTGCCTCCTACAGGATTTATCATATTACTGT
TGTTTGGAGTTGAAGGGCAAAGAGGAAGAAATACTGAAGGCACTTTCTCAAATGTGCAGCATAG
ACACAGGACTGACTTTTGCTGCAGTTCACTGCTTGTCTGGGAAGCGGCAAGGGAGCCTCATGCT
TTACCGGGCAAATAAGTATCCCAGAGACATGCTTGGGCCGGTTACCTTCATCTGGAAGTCTAGG
GAGACCCCAGGGGACGCCTCTGAGGAAAGGCAGCTGTGGATCTGGCTTCACCCAACTCTTAAAC
TGGCTGTCCTAGAGGAAATAAAAACAACGTGCCAGTGTTCAGAACCCGTCAAGCCAAGTGTCTG
TGTGCCTGCCCCACTCCTGACACCAGCCCAGGAAGACATTCAGGCAGGACTAGCTGATGACAAA
ATCGGCAAGAAAAGAAAAAGGAGAGATGATGGGGAAAATGCTAGACGAGCGAAGAAGACCATTG
GTGACGGGACAGGAGATCCCTGCCAGCCACGGTCGTGGCTCTCTCCCACTACAGGGATCGTAGT
CAGTGACTTGACCATGGAGATGAACAGGTTCCGGCTGGTCGGACCTCTTTCGCACTGTATCCTG
ACCTCAGCACTGAGGGCTGCTCCTGTACACAGAGGTGAGGAGGATGCAGAGGAGACACCGCATG
GCTGGTGGACTGACACGTGCAGGAGTCCTCATGGCCTTTCTCTTCACCAGAGACAAGAAGCAGT
GTTTCAGTTGTTGGGAGGGATATCGTCACCGGCAGAAATTCCAGCAGGTACTATTCTGGGATTG
ACAGTCAGGGACCCGAGAGTAAATTTGCCTCCACAGCGGTGCAGAGCTTTGCCTGATCCAGAAC
GATACCACGACAATGAGCAAGTTAAGCAGCTGCTTCTGGAGGGTGTGCCTGTGGAGTGTGCACA
CAGCTTCATCTGGAACCAGGATATCTGCCAGAGCGTTACAGAGAATAAAATCGTGGACCAGGAT
TTAAACCGCATGAGAAGCGAATTGCTGGTGCCCGGATCACAGCTTGTTTTAGGGGCTCGTGAAT
CCAAGATACCTATACTTCTGATTCAGCAGCCGGGAAAAGTGACTGGCGAAGACCGACTGGGCTG
GGGCAGTGGCTGGGACATCCTCCTTCCCAAGGGCTGGGGCATGGCCTTTTGGATTCCATTTATC
TACCGAGGTGCAAGGGTTGGTGGATTAAAAGAGGCTGCAGTACACTCTCAGTACAAACGGTCAC
CTAATGTCCCAGGCGACTTCCCAGACTGTCGTGCTGGCGTTCTCTTCGCTGAAGACCAAGCTAA
GGACCTTCTAGAGAAGTACCAAAGACGCCCCCCTGCTAAAAGGCCCAACTATGTTAAGCTTGGC
ACACTGGCTCCTTTCTGTTGTCCCTGGGAACAGCTGACTCGGGACTGGGAGTCCAGGATTCAGA
CCCAAGAAGCAGCTGTTATAGATTCAGTGCCTGGTGCTCAAGAGACTGACCCAAGAAGGCTTGG
AGTGCCTTGTGTCCCCAAAGAGACCTGCCAGCTATCGAATGAGGCAAGCATAGCTGAAAACCAA
CCTAGGAAGCCGGAAGTTACAGGCTGTCAAGCTCAGGCGGGGACTGAGGTGGCCCTGGAACAGA
ATGCCAGTGAGGACCACGCAGCTGCCACAGGTAGCCAGCTCTGTGTTGTTCGGAGTAGGAAACT
ACTGAAGCAACTCTCTTCCTGGTGTGGGCCCAGTTCTGAGGTCAGGAGGGCTCCCTGCAGAGGC
CAGCAAGAACTGACTAGAAAGGCTTGCCTGTCCATTCTGGCTGATTTCCCCAGAGCGCTGGTGT
GGGTCAGCTTGTCCCTGCTCAAGAAGGGCAGCCCAGAGCCACACACCATGATCTGTGTCCCATC
CAAGGAGGACTTGTTCCAGCTCAGTCAGGATCAGTGTTACCATGGACCCTGCGAATCCAGACAC
AGCGACCCATTTAAAAGCTTGATTCTGAAGGAGAAAGAAAAGAAGAAGAAGGAGAAGAGGCAGG
ATGGGGAGCAGGGGGCCTCCAAGGGCCAGGCAGCAGGGGCACCTACAGCTGGGCAGGAGGCTCG
GATTCAGGGGCTGTGGTCAGGCCCCCTTCCGGGGCTGACTTCACACTGCTCCAGGCCCCTCCTG
GGCTTCGTGACACATGGAGATTTCTCTATGGCTGTTGGCTGTGGAGAAGCCTTAGGGTTTGTTA
GTGTAACAGGCTTGCTGGAAATGTTGTCCAGCCAGTCAGCAGCCATGAGGGGCCTGGTCCTGCT
GCGGCCTCCGACCTCGCTGCAATACCGGTTTGCTAGAGTTACCATTGAGGTGTGAATTCGAGTT
TACACCCTTAACCTAGGTCCTAACTATTTTTGTCAAATTCCAAAGAGAGTCCTGGCCGTCTCGG
TCACCTGAATTAAAATACAATGTGGAACTGCTTGGAAAACAAGAATTAAAATTATATAATTATG
TGGATGACGATCTGTTTATAGTCTGAATCTTTTCCTGTCGTGGGGATATGCCGAATTGTTTAAC
ATGCTAGCTGAACACTCTGTATTAAACATTTTACAGTCACGTGATGTGCAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001124022	(Get FASTA)	NCBI Sequence Viewer
	NP_001421538	(Get FASTA)	NCBI Sequence Viewer
	XP_006241605	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM16417	(Get FASTA)	NCBI Sequence Viewer
	EDM16418	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000007190
	ENSRNOP00000007190.5
	ENSRNOP00000073143
	ENSRNOP00000073143.1
	ENSRNOP00000101658.1
	ENSRNOP00000112185.1

RefSeq Acc Id:

NP_001124022 ⟸ NM_001130550

- UniProtKB:

D4AE75 (UniProtKB/TrEMBL), A6HR04 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSNAKERKHAKKMRSQPSNVTLSSGFVTERDGKRHFGGKPSQSQKQELHSGTSRQWQIKMSPHL
LPESDANEQTSSKTMFKKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNS
LVFQTLPRHMRRRAMSHNVKRLPRRLQEMAKKEAEKAAHQKKEHSKNKCHKARRCHINRTLEFN
RRQQKNIWLETHIWHAKRFHMVKRWGYCLGERPTAKSHRACYRAMTDLCLLQDLSYYCCLELKG
KEEEILKALSQMCSIDTGLTFAAVHCLSGKRQGSLMLYRANKYPRDMLGPVTFIWKSRETPGDA
SEERQLWIWLHPTLKLAVLEEIKTTCQCSEPVKPSVCVPAPLLTPAQEDIQAGLADDKIGKKRK
RRDDGENARRAKKTIGDGTGDPCQPRSWLSPTTGIVVSDLTMEMNRFRLVGPLSHCILTSALRA
APVHRGEEDAEETPHGWWTDTCRSPHGLSLHQRQEAVFQLLGGISSPAEIPAGTILGLTVRDPR
VNLPPQRCRALPDPERYHVSEFICEEGMCTSSWSCAHWKPLSDHTDDPDNEQVKQLLLEGVPVE
CAHSFIWNQDICQSVTENKIVDQDLNRMRSELLVPGSQLVLGARESKIPILLIQQPGKVTGEDR
LGWGSGWDILLPKGWGMAFWIPFIYRGARVGGLKEAAVHSQYKRSPNVPGDFPDCRAGVLFAED
QAKDLLEKYQRRPPAKRPNYVKLGTLAPFCCPWEQLTRDWESRIQTQEAAVIDSVPGAQETDPR
RLGVPCVPKETCQLSNEASIAENQPRKPEVTGCQAQAGTEVALEQNASEDHAAATGSQLCVVRS
RKLLKQLSSWCGPSSEVRRAPCRGQQELTRKACLSILADFPRALVWVSLSLLKKGSPEPHTMIC
VPSKEDLFQLSQDQCYHGPCESRHSDPFKSLILKEKEKKKKEKRQDGEQGASKGQAAGAPTAGQ
EARIQGLWSGPLPGLTSHCSRPLLGFVTHGDFSMAVGCGEALGFVSVTGLLEMLSSQSAAMRGL
VLLRPPTSLQYRFARVTIEV

hide sequence

RefSeq Acc Id:

XP_006241605 ⟸ XM_006241543

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSNAKERKHAKKMRSQPSNVTLSSGFVTERDGKRHFGGKPSQSQKQELHSGTSRQWQIKMSPHL
LPESDANEQTSSKTMFKKKGGWKAGPEGTSQEIPKYITASTFAQARAAEISAMLKAVTQKSSNS
LVFQTLPRHMRRRAMSHNVKRLPRRLQEMAKKEAEKAAHQKKEHSKNKCHKARRCHINRTLEFN
RRQQKNIWLETHIWHAKRFHMVKRWGYCLGERPTAKSHRACYRAMTDLCLLQDLSYYCCLELKG
KEEEILKALSQMCSIDTGLTFAAVHCLSGKRQGSLMLYRANKYPRDMLGPVTFIWKSRETPGDA
SEERQLWIWLHPTLKLAVLEEIKTTCQCSEPVKPSVCVPAPLLTPAQEDIQAGLADDKIGKKRK
RRDDGENARRAKKTIGDGTGDPCQPRSWLSPTTGIVVSDLTMEMNRFRLVGPLSHCILTSALRA
APVHRGEEDAEETPHGWWTDTCRSPHGLSLHQRQEAVFQLLGGISSPAEIPAGTILGLTVRDPR
VNLPPQRCRALPDPERYHDNEQVKQLLLEGVPVECAHSFIWNQDICQSVTENKIVDQDLNRMRS
ELLVPGSQLVLGARESKIPILLIQQPGKVTGEDRLGWGSGWDILLPKGWGMAFWIPFIYRGARV
GGLKEAAVHSQYKRSPNVPGDFPDCRAGVLFAEDQAKDLLEKYQRRPPAKRPNYVKLGTLAPFC
CPWEQLTRDWESRIQTQEAAVIDSVPGAQETDPRRLGVPCVPKETCQLSNEASIAENQPRKPEV
TGCQAQAGTEVALEQNASEDHAAATGSQLCVVRSRKLLKQLSSWCGPSSEVRRAPCRGQQELTR
KACLSILADFPRALVWVSLSLLKKGSPEPHTMICVPSKEDLFQLSQDQCYHGPCESRHSDPFKS
LILKEKEKKKKEKRQDGEQGASKGQAAGAPTAGQEARIQGLWSGPLPGLTSHCSRPLLGFVTHG
DFSMAVGCGEALGFVSVTGLLEMLSSQSAAMRGLVLLRPPTSLQYRFARVTIEV

hide sequence

Ensembl Acc Id:

ENSRNOP00000073143 ⟸ ENSRNOT00000077730

Ensembl Acc Id:

ENSRNOP00000007190 ⟸ ENSRNOT00000007190

Ensembl Acc Id:

ENSRNOP00000112185 ⟸ ENSRNOT00000148795

Ensembl Acc Id:

ENSRNOP00000101658 ⟸ ENSRNOT00000169474

Protein Domains

POP1 C-terminal Pop1 N-terminal POPLD

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4AE75-F1-model_v2	AlphaFold	D4AE75	1-1044	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695283

Promoter ID:

EPDNEW_R5808

Type:

multiple initiation site

Name:

Pop1_1

Description:

POP1 homolog, ribonuclease P/MRP subunit

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R5809

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	73,270,449 - 73,270,509	EPDNEW

RGD ID:

13695295

Promoter ID:

EPDNEW_R5809

Type:

single initiation site

Name:

Pop1_2

Description:

POP1 homolog, ribonuclease P/MRP subunit

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R5808

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	73,274,034 - 73,274,094	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308609	AgrOrtholog
BioCyc Gene	G2FUF-33679	BioCyc
Ensembl Genes	ENSRNOG00000005243	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000007190	ENTREZGENE
	ENSRNOT00000007190.8	UniProtKB/TrEMBL
	ENSRNOT00000077730	ENTREZGENE
	ENSRNOT00000077730.3	UniProtKB/TrEMBL
	ENSRNOT00000148795.1	UniProtKB/TrEMBL
	ENSRNOT00000169474.1	UniProtKB/TrEMBL
InterPro	Pop1	UniProtKB/TrEMBL
	POP1_C	UniProtKB/TrEMBL
	POPLD	UniProtKB/TrEMBL
	RNase_P/MRP_POP1	UniProtKB/TrEMBL
KEGG Report	rno:315045	UniProtKB/TrEMBL
NCBI Gene	315045	ENTREZGENE
PANTHER	PTHR22731	UniProtKB/TrEMBL
	RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1	UniProtKB/TrEMBL
Pfam	POP1	UniProtKB/TrEMBL
	POP1_C	UniProtKB/TrEMBL
	POPLD	UniProtKB/TrEMBL
PhenoGen	Pop1	PhenoGen
RatGTEx	ENSRNOG00000005243	RatGTEx
UniProt	A0A0G2K4R5	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L0P8_RAT	UniProtKB/TrEMBL
	A0ABK0M2E5_RAT	UniProtKB/TrEMBL
	A6HR04	ENTREZGENE, UniProtKB/TrEMBL
	A6HR05	ENTREZGENE, UniProtKB/TrEMBL
	D4AE75	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2025-11-13	Pop1	POP1 ribonuclease P/MRP subunit	Pop1	POP1 homolog, ribonuclease P/MRP subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-07-20	Pop1	POP1 homolog, ribonuclease P/MRP subunit	Pop1	processing of precursor 1, ribonuclease P/MRP subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-07-17	Pop1	processing of precursor 1, ribonuclease P/MRP subunit	Pop1	processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-24	Pop1	processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)	Pop1	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Pop1	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)	Pop1_predicted	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Pop1_predicted	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)