POP1 (POP1 homolog, ribonuclease P/MRP subunit) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: POP1 (POP1 homolog, ribonuclease P/MRP subunit) Chlorocebus sabaeus
Analyze
Symbol: POP1
Name: POP1 homolog, ribonuclease P/MRP subunit
RGD ID: 18473141
Description: ENCODES a protein that exhibits ribonuclease P activity (ortholog); INVOLVED IN tRNA 5'-leader removal (inferred); tRNA decay (inferred); tRNA processing (inferred); PARTICIPATES IN tRNA maturation pathway; ASSOCIATED WITH anauxetic dysplasia 1 (ortholog); anauxetic dysplasia 2 (ortholog); Cohen syndrome (ortholog); FOUND IN multimeric ribonuclease P complex (inferred); nucleolar ribonuclease P complex (inferred); nucleolus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ribonucleases P/MRP protein subunit POP1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1893,031,600 - 93,074,700 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl893,043,277 - 93,074,818 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603947,664,062 - 47,707,173 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
POP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1893,031,600 - 93,074,700 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl893,043,277 - 93,074,818 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603947,664,062 - 47,707,173 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
POP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38898,117,293 - 98,159,835 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl898,117,293 - 98,159,835 (+)EnsemblGRCh38hg38GRCh38
GRCh37899,129,521 - 99,172,063 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36899,199,244 - 99,239,816 (+)NCBINCBI36Build 36hg18NCBI36
Build 34899,199,243 - 99,239,814NCBI
Celera895,315,383 - 95,357,929 (+)NCBICelera
Cytogenetic Map8q22.2NCBI
HuRef894,333,090 - 94,375,569 (+)NCBIHuRef
CHM1_1899,170,273 - 99,212,813 (+)NCBICHM1_1
T2T-CHM13v2.0899,242,783 - 99,285,304 (+)NCBIT2T-CHM13v2.0
Pop1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391534,495,457 - 34,530,799 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1534,495,450 - 34,530,794 (+)EnsemblGRCm39 Ensembl
GRCm381534,495,311 - 34,530,653 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1534,495,304 - 34,530,648 (+)EnsemblGRCm38mm10GRCm38
MGSCv371534,425,066 - 34,460,408 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361534,439,912 - 34,475,237 (+)NCBIMGSCv36mm8
Celera1535,123,159 - 35,157,920 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1514.34NCBI
Pop1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8767,590,502 - 67,618,187 (+)NCBIGRCr8
mRatBN7.2765,705,348 - 65,733,143 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl765,705,368 - 65,733,141 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx767,594,571 - 67,622,250 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0769,796,304 - 69,823,946 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0769,661,718 - 69,689,297 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0773,270,403 - 73,298,209 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl773,270,455 - 73,298,239 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0773,436,473 - 73,473,185 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4769,944,414 - 69,979,794 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1769,965,163 - 70,000,525 (+)NCBI
Celera762,806,384 - 62,834,025 (+)NCBICelera
Cytogenetic Map7q22NCBI
Pop1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541713,823,057 - 13,856,448 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541713,823,027 - 13,856,448 (+)NCBIChiLan1.0ChiLan1.0
POP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27115,458,813 - 115,501,190 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1891,000,256 - 91,042,640 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0894,754,028 - 94,796,374 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1896,938,574 - 96,980,896 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl896,944,588 - 96,979,328 (+)Ensemblpanpan1.1panPan2
POP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.113361,095 - 398,214 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl13361,157 - 396,628 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha13354,500 - 400,369 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.013509,663 - 555,581 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl13509,734 - 546,040 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.113353,061 - 398,925 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.013461,025 - 506,891 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.013467,078 - 512,927 (+)NCBIUU_Cfam_GSD_1.0
Pop1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530337,250,693 - 37,284,328 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647044,676,776 - 44,710,716 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647044,676,798 - 44,710,397 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl438,607,708 - 38,656,151 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1438,608,536 - 38,656,204 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2441,668,276 - 41,807,928 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pop1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247635,269,847 - 5,300,723 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247635,264,003 - 5,299,000 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 36 18 60
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000010430   ⟹   ENSCSAP00000008524
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl893,043,277 - 93,074,818 (+)Ensembl
RefSeq Acc Id: XM_008001178   ⟹   XP_007999369
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1893,031,600 - 93,074,700 (+)NCBI
Vero_WHO_p1.0NW_02366603947,664,062 - 47,707,173 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038000246   ⟹   XP_037856174
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603947,664,062 - 47,707,173 (-)NCBI
RefSeq Acc Id: XM_038000247   ⟹   XP_037856175
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366603947,664,062 - 47,707,143 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007999369 (Get FASTA)   NCBI Sequence Viewer  
  XP_037856174 (Get FASTA)   NCBI Sequence Viewer  
  XP_037856175 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000008524.1
Reference Protein Sequences
RefSeq Acc Id: XP_007999369   ⟸   XM_008001178
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RIT5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000008524   ⟸   ENSCSAT00000010430
RefSeq Acc Id: XP_037856174   ⟸   XM_038000246
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RIT5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037856175   ⟸   XM_038000247
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RIT5 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000012340 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000010430.1 UniProtKB/TrEMBL
InterPro Pop1 UniProtKB/TrEMBL
  Pop1_N UniProtKB/TrEMBL
  POPLD_dom UniProtKB/TrEMBL
NCBI Gene POP1 ENTREZGENE
PANTHER PTHR22731 UniProtKB/TrEMBL
  RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1 UniProtKB/TrEMBL
Pfam POP1 UniProtKB/TrEMBL
  POPLD UniProtKB/TrEMBL
UniProt A0A0D9RIT5 ENTREZGENE, UniProtKB/TrEMBL