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Gene: Ccl25 (C-C motif chemokine ligand 25) Rattus norvegicus

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Symbol:

Ccl25

Name:

C-C motif chemokine ligand 25

RGD ID:

1305530

Description:

Predicted to enable CCR10 chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including eosinophil chemotaxis; positive regulation of cell-matrix adhesion; and regulation of cell migration. Predicted to act upstream of or within chemotaxis; leukocyte migration; and lymphoid lineage cell migration. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human CCL25 (C-C motif chemokine ligand 25); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; amitrole.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

C-C motif chemokine 25; chemokine (C-C motif) ligand 25; LOC360750; MGC125074

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	7,505,231 - 7,514,402 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	7,505,235 - 7,514,385 (+)	Ensembl				GRCr8
mRatBN7.2	12	2,707,398 - 2,716,571 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	2,707,398 - 2,716,554 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	3,355,480 - 3,364,652 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	3,979,068 - 3,988,240 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	2,742,050 - 2,751,328 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	2,429,492 - 2,438,928 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	2,429,509 - 2,438,817 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	4,583,182 - 4,592,166 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	1,427,242 - 1,436,436 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	4,522,920 - 4,532,044 (+)	NCBI		Celera
RGSC_v3.1	12	1,427,553 - 1,439,348 (-)	NCBI
Cytogenetic Map	12	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Jaundice (IEP)

pleurisy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

6-propyl-2-thiouracil (EXP)

amitrole (EXP)

asperentin (ISO)

Azoxymethane (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Brevianamide A (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

chloroquine (ISO)

chlorpyrifos (ISO)

cobalt atom (ISO)

crotonaldehyde (ISO)

cyclophosphamide (ISO)

decabromodiphenyl ether (EXP)

deoxynivalenol (ISO)

dexamethasone (ISO)

dextran sulfate (ISO)

diethylstilbestrol (ISO)

ethanol (ISO)

folic acid (ISO)

graphene oxide (ISO)

hydrogen peroxide (ISO)

methapyrilene (ISO)

methimazole (EXP)

methotrexate (ISO)

monodansylcadaverine (ISO)

mycophenolic acid (ISO)

mycotoxin (ISO)

neoechinulin A (ISO)

nickel atom (ISO)

okadaic acid (ISO)

ozone (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

sodium arsenite (ISO)

sterigmatocystin (ISO)

sulfadimethoxine (EXP)

tetrachloromethane (ISO)

titanium dioxide (ISO)

TMC-120A (ISO)

tributylstannane (ISO)

trichloroethene (EXP)

triclosan (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antimicrobial humoral immune response mediated by antimicrobial peptide (ISO)

biological_process (ND)

cell chemotaxis (ISO)

chemotaxis (IEA,ISO)

G protein-coupled receptor signaling pathway (ISO)

immune response (IEA)

immune system process (IEA)

inflammatory response (IEA)

leukocyte migration (ISO)

negative regulation of leukocyte tethering or rolling (ISO)

positive regulation of cell-matrix adhesion (ISO)

Cellular Component

extracellular region (IEA)

extracellular space (IEA)

Molecular Function

CCR10 chemokine receptor binding (ISO)

chemokine activity (IEA,ISO)

chemokine receptor binding (ISO)

cytokine activity (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

chemokine mediated signaling pathway (IEA)

cytokine mediated signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Decreased expression of intestinal chemokine TECK/CCL25 in experimental obstructive jaundice and its reversal following internal biliary drainage.	Matsumoto T, etal., J Gastroenterol. 2008;43(5):390-6. Epub 2008 Jul 1.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Involvement of CC chemokines in gammadelta T lymphocyte trafficking during allergic inflammation: the role of CCL2/CCR2 pathway.	Penido C, etal., Int Immunol. 2008 Jan;20(1):129-39. Epub 2007 Dec 4.
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:10623805	PMID:10706668	PMID:12477932	PMID:12949249	PMID:15358618	PMID:18308860	PMID:19249122	PMID:21672573	PMID:23341447

Genomics

Comparative Map Data

Ccl25
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	7,505,231 - 7,514,402 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	7,505,235 - 7,514,385 (+)	Ensembl				GRCr8
mRatBN7.2	12	2,707,398 - 2,716,571 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	2,707,398 - 2,716,554 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	3,355,480 - 3,364,652 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	3,979,068 - 3,988,240 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	2,742,050 - 2,751,328 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	2,429,492 - 2,438,928 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	2,429,509 - 2,438,817 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	4,583,182 - 4,592,166 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	1,427,242 - 1,436,436 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	4,522,920 - 4,532,044 (+)	NCBI		Celera
RGSC_v3.1	12	1,427,553 - 1,439,348 (-)	NCBI
Cytogenetic Map	12	p12	NCBI

CCL25
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	8,052,341 - 8,062,650 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	8,052,293 - 8,062,665 (+)	Ensembl			hg38	GRCh38
GRCh37	19	8,117,225 - 8,127,534 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	8,023,934 - 8,033,547 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	19	8,023,933 - 8,033,534	NCBI
Celera	19	7,989,167 - 7,998,769 (+)	NCBI		Celera
Cytogenetic Map	19	p13.2	NCBI
HuRef	19	7,788,562 - 7,797,973 (+)	NCBI		HuRef
CHM1_1	19	8,117,421 - 8,127,895 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	8,053,362 - 8,063,660 (+)	NCBI		T2T-CHM13v2.0

Ccl25
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	4,375,207 - 4,410,020 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	4,375,210 - 4,410,020 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	4,325,205 - 4,360,020 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	4,325,210 - 4,360,020 (+)	Ensembl			mm10	GRCm38
MGSCv37	8	4,325,210 - 4,360,020 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	4,349,615 - 4,360,020 (+)	NCBI		MGSCv36	mm8
Celera	8	4,525,811 - 4,560,621 (+)	NCBI		Celera
Cytogenetic Map	8	A1.1	NCBI
cM Map	8	2.01	NCBI

Ccl25
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955563	1,251,526 - 1,256,650 (-)	Ensembl
ChiLan1.0	NW_004955563	1,249,098 - 1,255,469 (-)	NCBI	ChiLan1.0	ChiLan1.0

CCL25
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	12,734,718 - 12,745,594 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	11,851,953 - 11,862,815 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	7,307,109 - 7,363,983 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	8,208,273 - 8,217,780 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	8,208,273 - 8,217,780 (+)	Ensembl			panPan2	panpan1.1

CCL25
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	52,689,674 - 52,722,291 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	52,712,979 - 52,722,018 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	52,520,955 - 52,523,887 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	53,217,788 - 53,250,217 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	53,217,446 - 53,250,227 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	52,450,071 - 52,453,004 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	52,894,798 - 52,897,724 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	53,126,468 - 53,129,402 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ccl25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	212,836,389 - 212,861,308 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936588	4,973,476 - 4,998,365 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCL25
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	71,175,075 - 71,206,950 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	71,175,066 - 71,206,950 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	71,575,448 - 71,607,365 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCL25
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	7,496,463 - 7,504,637 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666081	306,230 - 353,525 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ccl25
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624828	975,656 - 981,610 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ccl25
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	2,486,639 - 2,495,970 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ccl25
21 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	232
Count of miRNA genes:	154
Interacting mature miRNAs:	180
Transcripts:	ENSRNOT00000037059
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312418	Kidm41	Kidney mass QTL 41	3.7	0.0001	kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	12	5921918	25247790	Rat
724526	Uae3	Urinary albumin excretion QTL 3	4.9	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	12	1	15486827	Rat
2306789	Ean6	Experimental allergic neuritis QTL 6	4.9		nervous system integrity trait (VT:0010566)	experimental autoimmune neuritis severity score (CMO:0001528)	12	1	29775522	Rat
7204484	Bp358	Blood pressure QTL 358		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	1	24849755	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	41361854	Rat
1357337	Gluco3	Glucose level QTL 3		0.0004	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	12	1	16966671	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1331739	Hrtrt14	Heart rate QTL 14	3.56232		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	12	1	38687564	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303568	Bw88	Body weight QTL 88	3		body mass (VT:0001259)	body weight (CMO:0000012)	12	1	28606299	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	1	33700600	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
61334	Gluco17	Glucose level QTL 17	6.3		adipocyte glucose uptake trait (VT:0004185)	adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)	12	1	16966671	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	1	38635130	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	28133365	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
1300174	Bw15	Body weight QTL 15	2.93		body mass (VT:0001259)	body weight loss (CMO:0001399)	12	1	28606299	Rat
1600391	Edcs2	Endometrial carcinoma susceptibility QTL2	3.5	0.01	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	12	1	11869600	Rat
1331787	Rf41	Renal function QTL 41	2.998		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	12	1	33700556	Rat

Markers in Region

BQ199385

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	2,715,726 - 2,715,942 (-)	MAPPER	mRatBN7.2
Rnor_6.0	12	2,430,121 - 2,430,336	NCBI	Rnor6.0
Rnor_5.0	12	4,583,811 - 4,584,026	UniSTS	Rnor5.0
RGSC_v3.4	12	1,427,871 - 1,428,086	UniSTS	RGSC3.4
Celera	12	4,531,192 - 4,531,407	UniSTS
RH 3.4 Map	12	0.0	UniSTS
Cytogenetic Map	12	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
16	9	13	60	52	52	30	26	30	159	55	5	50	50	59	22

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001037203	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC107945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000037059 ⟹ ENSRNOP00000037785

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	7,505,235 - 7,514,385 (+)	Ensembl
mRatBN7.2 Ensembl	12	2,707,398 - 2,716,554 (+)	Ensembl
Rnor_6.0 Ensembl	12	2,429,509 - 2,438,817 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093774 ⟹ ENSRNOP00000097134

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	2,707,398 - 2,713,749 (+)	Ensembl

RefSeq Acc Id:

NM_001037203 ⟹ NP_001032280

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	7,505,235 - 7,514,402 (+)	NCBI
mRatBN7.2	12	2,707,398 - 2,716,571 (+)	NCBI
Rnor_6.0	12	2,429,492 - 2,438,817 (-)	NCBI
Rnor_5.0	12	4,583,182 - 4,592,166 (-)	NCBI
RGSC_v3.4	12	1,427,242 - 1,436,436 (-)	RGD
Celera	12	4,522,920 - 4,532,044 (+)	RGD

Sequence:

show sequence

CACCCTACAAGCGGGCACCACCTTTCAGGACCAGAAAGGCACTGGTGGCCCCATTAAACCTTCA
GGTACCCAGAGAGGAGATCCAGCCTTCAGCATGAAACTGCAGCTGTTCGCCTGCCTGGCTGCCT
GCTTTGTTGGGGCCTGGGTGCCAGTTGTCCGTGCCCAAGGTGCCTTTGAAGACTGCTGCCTGGG
TTACCAGCCTAGGATCAAATGGAATGTTCTCCGGCATGCTAGGCATTATCACCAGCAGGAAGTG
AGTGGAAGCTGCAACCTCCGTGCTGTGATATTCTACTTCCGCCAGAAAGTAGTAGTGTGTGGGA
ATCCAGAGGACAAGGATGTGAAGAGGGCTGTGAAGATCTTAACAGCTAGGAAGCAGCCAGTCCA
CAGTCCCCAGAAGAGCACCTCAGACTATCCGACCGAAAGGAAGAAGTCAAACTACATGAAGTTC
AAGGTGGAGAACCCCAAGGGCACAAGGATGAGGAATGCCACCCTGGGTCATCCCAGGATGGTGA
TGATGTCCAGAAAGACCAACAATTAAGTTAAGTTACTCAGAGTAAGCAGCAGCTGGAGGATGGG
AGGAGTCCCCTGAGGAGCTGTCTTCTAGGCACCACAGTGCCAACGAACTCACGGAAGCTACAGT
TACCTGTACAAGACTGGACCCACCAACGTCTCAGCGCGTATGAGTAAGGACCTACCTATGCTAA
AGGCCCTACCACTCACCAATGAGCTATTGACTGTTGATGGTTACTGGGAGAAGGGAGTCTTTTT
GTTTTTGTTTTTTTCTCTCCAAAGCGTGGCTTGCCCATAGTCCAGTATATAATCCCCTATCTTC
ACTCAGACAAGCAACCCTAATTAAATGCAATGGCCATATACAAAAGGACAAAGGTTTGAATGGT
TTTGGGGCGGGGGAGCTTGTTAGGAAGAAGACATTAACAGGAGAGAGAGGAACTAGAGATCACT
GAGTGTGTGAAAATGGTCAAAATGCATACATATGTGAAATGGTCAAAGAATTAAAAAATAAAAA
TTTAAAAAGCTATTAAAAAGTGATTACTTACAGTGATGTGTGGTGTATGGCATGCCCTCAGGGG
GTTAGTGCCTATACTTCTGACTTAACCTGCTATAAATCAAGGTTCCTTTGACTCCTGTCAACAC
TCTGGAAAGCACTGTCTTTATATTTCTTAATTATTCTATAGCATGTTACAAAGGCTATGGATGA
TCTAGAATTGGTGTTGCTCAAGGAGTCTACAGTAGGATAATCACATGCTTGAGACCAGCCTGGG
CTACAGTGCAAGTTTGAGGCTAGCCTGGGATACAAAGCAAGACCCTATCTCAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_063271424 ⟹ XP_063127494

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	7,505,231 - 7,514,110 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001032280	(Get FASTA)	NCBI Sequence Viewer
	XP_063127494	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI07946	(Get FASTA)	NCBI Sequence Viewer
	EDL75004	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000037785
	ENSRNOP00000037785.4

RefSeq Acc Id:	NP_001032280 ⟸ NM_001037203
- Peptide Label:	precursor
- UniProtKB:	Q32PX4 (UniProtKB/TrEMBL), A6KQ79 (UniProtKB/TrEMBL), A0A8I6AS46 (UniProtKB/TrEMBL), F7F2H8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLQLFACLAACFVGAWVPVVRAQGAFEDCCLGYQPRIKWNVLRHARHYHQQEVSGSCNLRAVI FYFRQKVVVCGNPEDKDVKRAVKILTARKQPVHSPQKSTSDYPTERKKSNYMKFKVENPKGTRM RNATLGHPRMVMMSRKTNN hide sequence

Ensembl Acc Id:

ENSRNOP00000037785 ⟸ ENSRNOT00000037059

Ensembl Acc Id:

ENSRNOP00000097134 ⟸ ENSRNOT00000093774

RefSeq Acc Id:	XP_063127494 ⟸ XM_063271424
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AS46 (UniProtKB/TrEMBL), A6KQ79 (UniProtKB/TrEMBL), F7F2H8 (UniProtKB/TrEMBL), Q32PX4 (UniProtKB/TrEMBL)

Protein Domains

Chemokine interleukin-8-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q32PX4-F1-model_v2	AlphaFold	Q32PX4	1-147	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698379

Promoter ID:

EPDNEW_R8903

Type:

multiple initiation site

Name:

Ccl25_1

Description:

C-C motif chemokine ligand 25

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	2,438,827 - 2,438,887	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305530	AgrOrtholog
BioCyc Gene	G2FUF-20339	BioCyc
Ensembl Genes	ENSRNOG00000028531	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000037059	ENTREZGENE
	ENSRNOT00000037059.6	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.40	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7388091	IMAGE-MGC_LOAD
InterPro	Chemokine_b/g/d	UniProtKB/TrEMBL
	Chemokine_IL8	UniProtKB/TrEMBL
	Interleukin_8-like_sf	UniProtKB/TrEMBL
KEGG Report	rno:360750	UniProtKB/TrEMBL
MGC_CLONE	MGC:125074	IMAGE-MGC_LOAD
NCBI Gene	360750	ENTREZGENE
PANTHER	C-C MOTIF CHEMOKINE 25	UniProtKB/TrEMBL
	PTHR12015	UniProtKB/TrEMBL
Pfam	IL8	UniProtKB/TrEMBL
PhenoGen	Ccl25	PhenoGen
RatGTEx	ENSRNOG00000028531	RatGTEx
SMART	SCY	UniProtKB/TrEMBL
Superfamily-SCOP	Chemokine_IL8	UniProtKB/TrEMBL
UniProt	A0A8I6AS46	ENTREZGENE
	A6KQ79	ENTREZGENE, UniProtKB/TrEMBL
	F7F2H8	ENTREZGENE, UniProtKB/TrEMBL
	Q32PX4	ENTREZGENE
UniProt Secondary	Q32PX4	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-08	Ccl25	C-C motif chemokine ligand 25	Ccl25	chemokine (C-C motif) ligand 25	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Ccl25	chemokine (C-C motif) ligand 25	Ccl25_predicted	chemokine (C-C motif) ligand 25 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Ccl25_predicted	chemokine (C-C motif) ligand 25 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)