CCL25 (C-C motif chemokine ligand 25) - Rat Genome Database

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Gene: CCL25 (C-C motif chemokine ligand 25) Sus scrofa
Analyze
Symbol: CCL25
Name: C-C motif chemokine ligand 25
RGD ID: 14142791
Description: ENCODES a protein that exhibits CCR10 chemokine receptor binding (ortholog); chemokine receptor binding (ortholog); INVOLVED IN chemotaxis (ortholog); G protein-coupled receptor signaling pathway (ortholog); leukocyte migration (ortholog); ASSOCIATED WITH autistic disorder (ortholog); familial hemophagocytic lymphohistiocytosis 5 (ortholog); Jaundice (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C-C motif chemokine 25; chemokine (C-C motif) ligand 25; chemokine ligand 25; small-inducible cytokine A25
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl271,175,075 - 71,206,950 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1271,175,066 - 71,206,950 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2271,575,448 - 71,607,365 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:15242943   PMID:16839611   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CCL25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl271,175,075 - 71,206,950 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1271,175,066 - 71,206,950 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2271,575,448 - 71,607,365 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCL25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38198,052,341 - 8,062,650 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl198,052,318 - 8,062,660 (+)EnsemblGRCh38hg38GRCh38
GRCh37198,117,225 - 8,127,534 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36198,023,934 - 8,033,547 (+)NCBINCBI36Build 36hg18NCBI36
Build 34198,023,933 - 8,033,534NCBI
Celera197,989,167 - 7,998,769 (+)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef197,788,562 - 7,797,973 (+)NCBIHuRef
CHM1_1198,117,421 - 8,127,895 (+)NCBICHM1_1
T2T-CHM13v2.0198,053,362 - 8,063,660 (+)NCBIT2T-CHM13v2.0
Ccl25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3984,375,207 - 4,410,020 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl84,375,210 - 4,410,020 (+)EnsemblGRCm39 Ensembl
GRCm3884,325,205 - 4,360,020 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl84,325,210 - 4,360,020 (+)EnsemblGRCm38mm10GRCm38
MGSCv3784,325,210 - 4,360,020 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3684,349,615 - 4,360,020 (+)NCBIMGSCv36mm8
Celera84,525,811 - 4,560,621 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map82.01NCBI
Ccl25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8127,505,231 - 7,514,402 (+)NCBIGRCr8
mRatBN7.2122,707,398 - 2,716,571 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl122,707,398 - 2,716,554 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx123,355,480 - 3,364,652 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0123,979,068 - 3,988,240 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0122,742,050 - 2,751,328 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,429,492 - 2,438,928 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,429,509 - 2,438,817 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,583,182 - 4,592,166 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4121,427,242 - 1,436,436 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1121,427,553 - 1,439,348 (-)NCBI
Celera124,522,920 - 4,532,044 (+)NCBICelera
Cytogenetic Map12p12NCBI
Ccl25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555631,249,098 - 1,255,469 (-)NCBIChiLan1.0ChiLan1.0
CCL25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22012,734,718 - 12,745,594 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11911,851,953 - 11,862,815 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0197,307,109 - 7,363,983 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1198,208,273 - 8,217,780 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl198,208,273 - 8,217,780 (+)Ensemblpanpan1.1panPan2
CCL25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12052,689,674 - 52,722,291 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2052,712,979 - 52,722,018 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2052,520,955 - 52,523,887 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02053,217,788 - 53,250,217 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2053,217,446 - 53,250,227 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12052,450,071 - 52,453,004 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02052,894,798 - 52,897,724 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02053,126,468 - 53,129,402 (+)NCBIUU_Cfam_GSD_1.0
Ccl25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118212,836,389 - 212,861,308 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365884,973,476 - 4,998,365 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCL25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.167,496,463 - 7,504,637 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666081306,230 - 353,525 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccl25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624828975,656 - 981,610 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCL25
445 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 5
Low 4 3 3 5 2 23 2 3 1
Below cutoff 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000047746   ⟹   ENSSSCP00000045987
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl271,175,075 - 71,206,950 (-)Ensembl
RefSeq Acc Id: NM_001025214   ⟹   NP_001020385
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1271,175,463 - 71,178,256 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005661258   ⟹   XP_005661315
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1271,175,066 - 71,206,950 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005661259   ⟹   XP_005661316
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1271,175,066 - 71,178,563 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021081930   ⟹   XP_020937589
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1271,175,066 - 71,178,552 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005661315   ⟸   XM_005661258
- Peptide Label: isoform X2
- UniProtKB: Q4PR21 (UniProtKB/Swiss-Prot),   A0A4X1VMC8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005661316   ⟸   XM_005661259
- Peptide Label: isoform X2
- UniProtKB: Q4PR21 (UniProtKB/Swiss-Prot),   A0A4X1VMC8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020937589   ⟸   XM_021081930
- Peptide Label: isoform X1
- UniProtKB: A0A8D0UA00 (UniProtKB/TrEMBL),   A0A8D1IVQ3 (UniProtKB/TrEMBL),   A0A8D0J4X0 (UniProtKB/TrEMBL),   A0A8D1BX56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001020385   ⟸   NM_001025214
- Peptide Label: precursor
- UniProtKB: Q4PR21 (UniProtKB/Swiss-Prot),   A0A4X1VMC8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000045987   ⟸   ENSSSCT00000047746
Protein Domains
Chemokine interleukin-8-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000013593 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSSSCG00005021195 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00015066934 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00025016057 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00030007657 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00035077557 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00040003963 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00045034044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00050050284 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00055012540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00060017990 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00065056447 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00070025542 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000047746 ENTREZGENE
  ENSSSCT00000047746.3 UniProtKB/Swiss-Prot
  ENSSSCT00005033431.1 UniProtKB/TrEMBL
  ENSSSCT00005033454.1 UniProtKB/TrEMBL
  ENSSSCT00005033472.1 UniProtKB/TrEMBL
  ENSSSCT00005033487.1 UniProtKB/TrEMBL
  ENSSSCT00005033508.1 UniProtKB/Swiss-Prot
  ENSSSCT00015089639.1 UniProtKB/Swiss-Prot
  ENSSSCT00015089729.1 UniProtKB/TrEMBL
  ENSSSCT00025021545.1 UniProtKB/Swiss-Prot
  ENSSSCT00025021572.1 UniProtKB/TrEMBL
  ENSSSCT00030010273.1 UniProtKB/Swiss-Prot
  ENSSSCT00030010281.1 UniProtKB/TrEMBL
  ENSSSCT00035105682.1 UniProtKB/TrEMBL
  ENSSSCT00035105703.1 UniProtKB/TrEMBL
  ENSSSCT00035105717.1 UniProtKB/Swiss-Prot
  ENSSSCT00040005027.1 UniProtKB/TrEMBL
  ENSSSCT00040005034.1 UniProtKB/TrEMBL
  ENSSSCT00040005039.1 UniProtKB/Swiss-Prot
  ENSSSCT00045058238.1 UniProtKB/TrEMBL
  ENSSSCT00045058285.1 UniProtKB/TrEMBL
  ENSSSCT00045058329.1 UniProtKB/TrEMBL
  ENSSSCT00045058370.1 UniProtKB/TrEMBL
  ENSSSCT00045058411.1 UniProtKB/Swiss-Prot
  ENSSSCT00050068409.1 UniProtKB/Swiss-Prot
  ENSSSCT00050068414.1 UniProtKB/TrEMBL
  ENSSSCT00055024658.1 UniProtKB/Swiss-Prot
  ENSSSCT00055024697.1 UniProtKB/TrEMBL
  ENSSSCT00060024110.1 UniProtKB/Swiss-Prot
  ENSSSCT00060024115.1 UniProtKB/TrEMBL
  ENSSSCT00065077245.1 UniProtKB/Swiss-Prot
  ENSSSCT00065077249.1 UniProtKB/TrEMBL
  ENSSSCT00070051060.1 UniProtKB/Swiss-Prot
  ENSSSCT00070051063.1 UniProtKB/TrEMBL
  ENSSSCT00070051065.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Chemokine_b/g/d UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:448799 UniProtKB/Swiss-Prot
NCBI Gene CCL25 ENTREZGENE
PANTHER C-C MOTIF CHEMOKINE 25 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SCY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A4X1VMC8 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VMX5_PIG UniProtKB/TrEMBL
  A0A8D0J4X0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0J7N2_PIG UniProtKB/TrEMBL
  A0A8D0UA00 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1BX56 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1IVQ3 ENTREZGENE, UniProtKB/TrEMBL
  CCL25_PIG UniProtKB/Swiss-Prot, ENTREZGENE
  Q6EKW6_PIG UniProtKB/TrEMBL
VGNC ID VGNC:99612 ENTREZGENE