Cdk19 (cyclin-dependent kinase 19) - Rat Genome Database

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Gene: Cdk19 (cyclin-dependent kinase 19) Rattus norvegicus
Analyze
Symbol: Cdk19
Name: cyclin-dependent kinase 19
RGD ID: 1305435
Description: Predicted to enable protein serine/threonine kinase activity. Involved in cellular response to lipopolysaccharide and positive regulation of apoptotic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 87. Orthologous to human CDK19 (cyclin dependent kinase 19); PARTICIPATES IN RNA polymerase II transcription pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Cdc2l6; Cdk11; cell division cycle 2-like 6 (CDK8-like); cell division protein kinase 19; cyclin-dependent kinase (CDC2-like) 11; LOC309804
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82045,324,911 - 45,465,121 (+)NCBIGRCr8
mRatBN7.22043,770,409 - 43,910,629 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2043,770,409 - 43,910,628 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2045,519,393 - 45,659,600 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02045,178,592 - 45,318,717 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02045,927,534 - 46,067,387 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02045,458,499 - 45,598,799 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2045,458,558 - 45,598,798 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02047,178,053 - 47,318,293 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42044,527,463 - 44,670,028 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12044,550,571 - 44,690,526 (+)NCBI
Celera2044,473,908 - 44,614,279 (+)NCBICelera
Cytogenetic Map20q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cyclin D3/CDK11(p58) complex involved in Schwann cells proliferation repression caused by lipopolysaccharide. Duan Y, etal., Inflammation. 2010 Jun;33(3):189-99. doi: 10.1007/s10753-009-9173-8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Increased expression of CDK11p58 and cyclin D3 following spinal cord injury in rats. Ji Y, etal., Mol Cell Biochem. 2008 Feb;309(1-2):49-60. Epub 2007 Nov 16.
4. LPS-stimulating astrocyte-conditioned medium causes neuronal apoptosis via increasing CDK11(p58) expression in PC12 cells through downregulating AKT pathway. Liu X, etal., Cell Mol Neurobiol. 2013 Aug;33(6):779-87. doi: 10.1007/s10571-013-9945-4. Epub 2013 May 24.
5. The functional interaction between CDK11p58 and beta-1,4-galactosyltransferase I involved in astrocyte activation caused by lipopolysaccharide. Liu X, etal., Inflammation. 2012 Aug;35(4):1365-77. doi: 10.1007/s10753-012-9450-9.
6. CDK11(p58) promotes rat astrocyte inflammatory response via activating p38 and JNK pathways induced by lipopolysaccharide. Liu X, etal., Neurochem Res. 2012 Mar;37(3):563-73. doi: 10.1007/s11064-011-0643-7. Epub 2011 Nov 27.
7. The Mediator complex and transcription regulation. Poss ZC, etal., Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation

Genomics

Comparative Map Data
Cdk19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82045,324,911 - 45,465,121 (+)NCBIGRCr8
mRatBN7.22043,770,409 - 43,910,629 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2043,770,409 - 43,910,628 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2045,519,393 - 45,659,600 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02045,178,592 - 45,318,717 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02045,927,534 - 46,067,387 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02045,458,499 - 45,598,799 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2045,458,558 - 45,598,798 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02047,178,053 - 47,318,293 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42044,527,463 - 44,670,028 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12044,550,571 - 44,690,526 (+)NCBI
Celera2044,473,908 - 44,614,279 (+)NCBICelera
Cytogenetic Map20q12NCBI
CDK19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386110,609,978 - 110,815,855 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6110,609,978 - 110,815,958 (-)EnsemblGRCh38hg38GRCh38
GRCh376110,931,181 - 111,137,058 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366111,037,874 - 111,243,105 (-)NCBINCBI36Build 36hg18NCBI36
Build 346111,037,873 - 111,243,105NCBI
Celera6111,677,771 - 111,883,024 (-)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6108,502,782 - 108,707,560 (-)NCBIHuRef
CHM1_16111,194,368 - 111,399,578 (-)NCBICHM1_1
T2T-CHM13v2.06111,788,546 - 111,994,459 (-)NCBIT2T-CHM13v2.0
Cdk19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391040,225,283 - 40,359,814 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1040,215,560 - 40,359,814 (+)EnsemblGRCm39 Ensembl
GRCm381040,349,287 - 40,483,818 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1040,339,564 - 40,483,818 (+)EnsemblGRCm38mm10GRCm38
MGSCv371040,069,114 - 40,203,624 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361040,038,753 - 40,171,561 (+)NCBIMGSCv36mm8
Celera1041,236,080 - 41,370,778 (+)NCBICelera
Cytogenetic Map10B1NCBI
cM Map1021.94NCBI
Cdk19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541135,312,722 - 35,412,246 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541135,312,722 - 35,411,951 (-)NCBIChiLan1.0ChiLan1.0
CDK19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25130,619,449 - 130,825,485 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16128,505,435 - 128,711,500 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06108,413,832 - 108,619,053 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16112,483,434 - 112,686,987 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6112,483,434 - 112,686,987 (-)Ensemblpanpan1.1panPan2
CDK19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11267,227,374 - 67,369,481 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1267,231,463 - 67,327,084 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1267,045,409 - 67,207,137 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01268,105,399 - 68,267,587 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1268,107,897 - 68,266,935 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11267,456,135 - 67,618,065 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01267,302,282 - 67,464,163 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01267,580,480 - 67,742,370 (-)NCBIUU_Cfam_GSD_1.0
Cdk19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946102,167,888 - 102,292,372 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365646,442,809 - 6,567,210 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365646,443,041 - 6,584,767 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl176,589,052 - 76,793,278 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1176,589,050 - 76,793,476 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,115,818 - 86,230,304 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDK19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11363,069,270 - 63,294,012 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1363,069,864 - 63,293,998 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604035,373,637 - 35,589,878 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249161,625,073 - 1,812,296 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249161,625,330 - 1,812,026 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdk19
820 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:584
Count of miRNA genes:265
Interacting mature miRNAs:360
Transcripts:ENSRNOT00000000713
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)201761783247606836Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202510672254435887Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
1598869Memor6Memory QTL 63.1exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)202924438854435887Rat
70158Bp60Blood pressure QTL 603arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)203161428444396023Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202520973454435887Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202510672254435887Rat
2317880Alcrsp25Alcohol response QTL 252.3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)201769755054435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202510672254435887Rat

Markers in Region
D20Rat81  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22043,791,439 - 43,791,616 (+)MAPPERmRatBN7.2
Rnor_6.02045,479,799 - 45,479,975NCBIRnor6.0
Rnor_5.02047,199,294 - 47,199,470UniSTSRnor5.0
RGSC_v3.42044,549,492 - 44,549,668RGDRGSC3.4
RGSC_v3.42044,549,493 - 44,549,669UniSTSRGSC3.4
RGSC_v3.12044,572,503 - 44,572,679RGD
Celera2044,495,121 - 44,495,297UniSTS
FHH x ACI Map2031.8599RGD
FHH x ACI Map2031.8599UniSTS
Cytogenetic Map20q12UniSTS
RH137912  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22043,909,945 - 43,910,114 (+)MAPPERmRatBN7.2
Rnor_6.02045,598,116 - 45,598,284NCBIRnor6.0
Rnor_5.02047,317,611 - 47,317,779UniSTSRnor5.0
RGSC_v3.42044,669,346 - 44,669,514UniSTSRGSC3.4
Celera2044,613,597 - 44,613,765UniSTS
RH 3.4 Map20481.5UniSTS
Cytogenetic Map20q12UniSTS
RH129982  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22043,910,389 - 43,910,584 (+)MAPPERmRatBN7.2
Rnor_6.02045,598,560 - 45,598,754NCBIRnor6.0
Rnor_5.02047,318,055 - 47,318,249UniSTSRnor5.0
RGSC_v3.42044,669,790 - 44,669,984UniSTSRGSC3.4
Celera2044,614,041 - 44,614,235UniSTS
RH 3.4 Map20482.8UniSTS
Cytogenetic Map20q12UniSTS
AU046883  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22043,859,390 - 43,859,582 (+)MAPPERmRatBN7.2
Rnor_6.02045,547,745 - 45,547,936NCBIRnor6.0
Rnor_5.02047,267,240 - 47,267,431UniSTSRnor5.0
RGSC_v3.42044,617,484 - 44,617,675UniSTSRGSC3.4
Celera2044,563,054 - 44,563,245UniSTS
Cytogenetic Map20q12UniSTS
BM383904  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22043,915,311 - 43,915,509 (+)MAPPERmRatBN7.2
Rnor_6.02045,603,482 - 45,603,679NCBIRnor6.0
Rnor_5.02047,322,977 - 47,323,174UniSTSRnor5.0
RGSC_v3.42044,674,712 - 44,674,909UniSTSRGSC3.4
Celera2044,618,963 - 44,619,160UniSTS
RH 3.4 Map20469.7UniSTS
Cytogenetic Map20q12UniSTS
BQ209200  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22043,773,182 - 43,773,395 (+)MAPPERmRatBN7.2
Rnor_6.02045,461,332 - 45,461,544NCBIRnor6.0
Rnor_5.02047,180,827 - 47,181,039UniSTSRnor5.0
RGSC_v3.42044,530,237 - 44,530,449UniSTSRGSC3.4
Celera2044,476,682 - 44,476,894UniSTS
RH 3.4 Map20487.01UniSTS
Cytogenetic Map20q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000000713   ⟹   ENSRNOP00000000713
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2043,770,409 - 43,910,628 (+)Ensembl
Rnor_6.0 Ensembl2045,458,558 - 45,598,798 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105498   ⟹   ENSRNOP00000083054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2043,770,409 - 43,910,628 (+)Ensembl
RefSeq Acc Id: NM_001107634   ⟹   NP_001101104
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82045,324,911 - 45,465,120 (+)NCBI
mRatBN7.22043,770,409 - 43,910,628 (+)NCBI
Rnor_6.02045,458,558 - 45,598,798 (+)NCBI
Rnor_5.02047,178,053 - 47,318,293 (+)NCBI
RGSC_v3.42044,527,463 - 44,670,028 (+)RGD
Celera2044,473,908 - 44,614,279 (+)RGD
Sequence:
RefSeq Acc Id: XM_008772985   ⟹   XP_008771207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82045,325,161 - 45,465,121 (+)NCBI
mRatBN7.22043,770,666 - 43,910,629 (+)NCBI
Rnor_6.02045,458,864 - 45,598,799 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008772986   ⟹   XP_008771208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82045,419,538 - 45,465,121 (+)NCBI
mRatBN7.22043,865,049 - 43,910,629 (+)NCBI
Rnor_6.02045,553,455 - 45,598,799 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601657   ⟹   XP_017457146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82045,325,164 - 45,465,121 (+)NCBI
mRatBN7.22043,770,442 - 43,910,629 (+)NCBI
Rnor_6.02045,458,499 - 45,598,799 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001101104   ⟸   NM_001107634
- UniProtKB: D3ZDM6 (UniProtKB/TrEMBL),   A6KIJ0 (UniProtKB/TrEMBL),   A0A8I5ZUQ1 (UniProtKB/TrEMBL),   A6KIJ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008771207   ⟸   XM_008772985
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008771208   ⟸   XM_008772986
- Peptide Label: isoform X3
- UniProtKB: A6KIJ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457146   ⟸   XM_017601657
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000000713   ⟸   ENSRNOT00000000713
Ensembl Acc Id: ENSRNOP00000083054   ⟸   ENSRNOT00000105498
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZDM6-F1-model_v2 AlphaFold D3ZDM6 1-501 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701660
Promoter ID:EPDNEW_R12183
Type:initiation region
Name:Cdk19_1
Description:cyclin-dependent kinase 19
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02045,458,586 - 45,458,646EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305435 AgrOrtholog
BioCyc Gene G2FUF-3426 BioCyc
Ensembl Genes ENSRNOG00000000583 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000713.6 UniProtKB/TrEMBL
  ENSRNOT00000105498.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro CDK UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_prot_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:309804 UniProtKB/TrEMBL
NCBI Gene 309804 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/TrEMBL
  CYCLIN-DEPENDENT KINASE 19 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Cdk19 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000583 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A8I5ZUQ1 ENTREZGENE, UniProtKB/TrEMBL
  A6KIJ0 ENTREZGENE, UniProtKB/TrEMBL
  A6KIJ1 ENTREZGENE, UniProtKB/TrEMBL
  A6KIJ3 ENTREZGENE, UniProtKB/TrEMBL
  D3ZDM6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-29 Cdk19  cyclin-dependent kinase 19  Cdc2l6  cell division cycle 2-like 6 (CDK8-like)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Cdc2l6  cell division cycle 2-like 6 (CDK8-like)   Cdc2l6_predicted  cell division cycle 2-like 6 (CDK8-like) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Cdc2l6_predicted  cell division cycle 2-like 6 (CDK8-like) (predicted)  Cdk11_predicted  cyclin-dependent kinase (CDC2-like) 11 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Cdk11_predicted  cyclin-dependent kinase (CDC2-like) 11 (predicted)      Symbol and Name status set to approved 70820 APPROVED