Srprb (SRP receptor subunit beta)

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Gene: Srprb (SRP receptor subunit beta) Rattus norvegicus

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Symbol:

Srprb

Name:

SRP receptor subunit beta

RGD ID:

1304698

Description:

Enables ubiquitin protein ligase binding activity. Predicted to be involved in protein targeting to ER. Predicted to be located in cytoplasmic microtubule and membrane. Predicted to be part of signal recognition particle receptor complex. Orthologous to human SRPRB (SRP receptor subunit beta); INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil; amiodarone.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Ab2-417; Ba1-667; Cc1-8; LOC300965; signal recognition particle receptor subunit beta; signal recognition particle receptor, B subunit; SR-beta; SRP receptor beta subunit

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SRPRB (SRP receptor subunit beta)	HGNC	HomoloGene, NCBI
Mus musculus (house mouse):	Srprb (signal recognition particle receptor, B subunit)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Srprb (SRP receptor subunit beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SRPRB (SRP receptor subunit beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SRPRB (SRP receptor subunit beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Srprb (SRP receptor subunit beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SRPRB (SRP receptor subunit beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Srprb (SRP receptor subunit beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SRPRB (SRP receptor subunit beta)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Srprb (signal recognition particle receptor, B subunit)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	srprb (SRP receptor subunit beta)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	R186.3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	R186.3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SRP102	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	SRP102	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	SrpRbeta	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	srprb	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	srprb	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	112,647,577 - 112,661,524 (-)	NCBI	GRCr8	GRCr8		GRCr8
mRatBN7.2	8	103,768,685 - 103,782,632 (-)	NCBI	mRatBN7.2	mRatBN7.2
UTH_Rnor_SHR_Utx	8	109,428,103 - 109,442,062 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	107,627,269 - 107,641,228 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	105,469,951 - 105,483,910 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	111,673,479 - 111,687,426 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	8	111,064,462 - 111,078,409 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	108,196,684 - 108,210,631 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	103,146,886 - 103,160,831 (-)	NCBI		Celera
RGSC_v3.1	8	108,216,139 - 108,230,086 (-)	NCBI
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-palmitoylglycerol (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

all-trans-retinoic acid (ISO)

amiodarone (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

buspirone (EXP)

caffeine (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

clofibrate (EXP)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

Enterolactone (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

flutamide (EXP)

fulvestrant (ISO)

furan (EXP)

genistein (ISO)

gentamycin (EXP)

glafenine (EXP)

hydrogen peroxide (ISO)

ivermectin (ISO)

L-ethionine (EXP)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methidathion (ISO)

omeprazole (EXP)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (EXP)

propiconazole (ISO)

resveratrol (ISO)

silicon dioxide (ISO)

sodium arsenite (EXP,ISO)

Soman (EXP)

tamoxifen (ISO)

temozolomide (ISO)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (EXP,ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

tolcapone (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

tunicamycin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein targeting to ER (IBA)

Cellular Component

cytoplasm (ISO)

cytoplasmic microtubule (ISO,ISS)

endoplasmic reticulum membrane (IEA)

membrane (ISO)

signal recognition particle receptor complex (IBA,ISO)

Molecular Function

GTP binding (IEA)

nucleotide binding (IEA)

ubiquitin protein ligase binding (IPI)

References

References - curated

#	Reference Title	Reference Citation
1.	Pirh2 interacts with and ubiquitylates signal recognition particle receptor beta subunit.	Abe K, etal., Biomed Res. 2008 Feb;29(1):53-60.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:12477932	PMID:19664239	PMID:22375059	PMID:23264731	PMID:25002582

Genomics

Comparative Map Data

Srprb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	112,647,577 - 112,661,524 (-)	NCBI	GRCr8	GRCr8		GRCr8
mRatBN7.2	8	103,768,685 - 103,782,632 (-)	NCBI	mRatBN7.2	mRatBN7.2
UTH_Rnor_SHR_Utx	8	109,428,103 - 109,442,062 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	107,627,269 - 107,641,228 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	105,469,951 - 105,483,910 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	111,673,479 - 111,687,426 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	8	111,064,462 - 111,078,409 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	108,196,684 - 108,210,631 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	103,146,886 - 103,160,831 (-)	NCBI		Celera
RGSC_v3.1	8	108,216,139 - 108,230,086 (-)	NCBI
Cytogenetic Map	8	q32	NCBI

SRPRB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	133,784,023 - 133,828,574 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	133,784,023 - 133,825,772 (+)	Ensembl			hg38	GRCh38
GRCh37	3	133,502,867 - 133,547,418 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	135,007,367 - 135,022,213 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	135,007,374 - 135,022,221	NCBI
Celera	3	131,929,996 - 131,966,138 (+)	NCBI		Celera
Cytogenetic Map	3	q22.1	NCBI
HuRef	3	130,882,540 - 130,918,525 (+)	NCBI		HuRef
CHM1_1	3	133,466,291 - 133,504,281 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	136,529,221 - 136,573,768 (+)	NCBI		T2T-CHM13v2.0

Srprb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	103,065,232 - 103,079,264 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	103,065,231 - 103,079,336 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	103,188,033 - 103,202,065 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	103,188,032 - 103,202,137 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	103,090,363 - 103,104,395 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	103,046,183 - 103,060,215 (-)	NCBI		MGSCv36	mm8
Celera	9	102,738,664 - 102,752,618 (-)	NCBI		Celera
Cytogenetic Map	9	F1	NCBI
cM Map	9	55.0	NCBI

Srprb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955501	4,784,266 - 4,796,587 (-)	Ensembl
ChiLan1.0	NW_004955501	4,784,266 - 4,796,587 (-)	NCBI	ChiLan1.0	ChiLan1.0

SRPRB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	131,714,334 - 131,744,840 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	131,719,063 - 131,748,877 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	130,850,953 - 130,865,940 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	138,325,988 - 138,342,056 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	138,325,988 - 138,342,056 (+)	Ensembl			panPan2	panpan1.1

SRPRB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	30,687,508 - 30,711,275 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	30,687,554 - 30,710,245 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	30,666,628 - 30,690,423 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	31,207,919 - 31,231,735 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	31,207,938 - 31,232,693 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	30,901,725 - 30,925,521 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	30,959,521 - 30,983,300 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	31,207,112 - 31,230,923 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Srprb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	70,191,983 - 70,207,044 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	6,952,540 - 6,966,661 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	6,952,472 - 6,967,542 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SRPRB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	74,975,677 - 75,010,212 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	74,976,030 - 75,010,200 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	82,474,463 - 82,508,621 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Srprb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	10,114,281 - 10,133,794 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624730	10,114,870 - 10,131,833 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Srprb
41 total Variants

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	105462581	132782436	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	70041301	121080908	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	102413464	132782436	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	103375781	129871912	Rat
8693654	Alc32	Alcohol consumption QTL 32	2	0.755	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	8	97492344	116428905	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39106363	114525825	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
631217	Activ1	Activity QTL 1	15.9		voluntary movement trait (VT:0003491)	number of photobeam interruptions in an experimental apparatus (CMO:0001517)	8	111249511	117802327	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	98145073	122898010	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Markers in Region

BE120985

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	103,782,833 - 103,783,024 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	111,687,628 - 111,687,818	NCBI	Rnor6.0
Rnor_5.0	8	111,078,611 - 111,078,801	UniSTS	Rnor5.0
RGSC_v3.4	8	108,210,833 - 108,211,023	UniSTS	RGSC3.4
Celera	8	103,161,033 - 103,161,223	UniSTS
RH 3.4 Map	8	1156.3	UniSTS
Cytogenetic Map	8	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
7	1	18	49	67	138	95	11	48	36	32	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC119318	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY325214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY325230	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY325241	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC098951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BF523222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BF525252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BQ204036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231594	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232246	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

NM_001013252 ⟹ NP_001013270

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	112,647,577 - 112,661,524 (-)	NCBI
mRatBN7.2	8	103,768,685 - 103,782,632 (-)	NCBI
Rnor_6.0	8	111,673,479 - 111,687,426 (-)	NCBI
Rnor_5.0	8	111,064,462 - 111,078,409 (-)	NCBI
RGSC_v3.4	8	108,196,684 - 108,210,631 (-)	RGD
Celera	8	103,146,886 - 103,160,831 (-)	RGD

Sequence:

show sequence

GGGAAGACCACGGACCTCCTTCATGGCTTCCGCGAACACCCGGCGTGTTGGGGATGGTGCCGGG
GGCGCCTTCCAGCCTTACCTCGACTCCTTGCGACAGGAGCTGCAGCAGAGGGATCCGACGCTGC
TGTCCGTGGCGGTGGCGGTACTGGCGGTGCTGCTGACGCTGGTGTTCTGGAAGTTCATTTGGAG
CCGAAAGAGCAGTCAGAGAGCTGTCCTCTTTGTTGGTCTCTGCGACTCTGGGAAAACATTGCTG
TTCGTCAGGTTGCTAACAGGCCAATACAGAGACACACAGACTTCTATTACCGATAGTTCTGCTA
TATACAAAGTCAACAACAACAGGGGTAACAGCCTGACTTTGATTGACCTCCCCGGGCACGAGAG
CTTGAGGCTTCAGTTCTTAGATCGCTTTAAGTCTTCAGCCAGGGCTGTGGTGTTCGTGGTGGAC
AGTGCAACGTTCCAGCGGGAGGTGAAAGATGTGGCTGAGTTTCTGTACCAGGTCCTCATCGACA
GCATGGCTCTGAAGAACACACCGGCCTTCTTAGTAGCCTGCAATAAGCAAGATATCGCAATGGC
AAAATCAGCAAAGTTAATTCAGCAGCAGCTGGAGAAGGAGCTTAACACCTTGCGAGTCACCCGG
TCTGCTGCTCCCAGCACCCTGGACAGTTCCAGTACTGCACCTGCTCAGCTGGGAAAGAAAGGCA
AAGAATTTGAATTTTCCCAGTTGCCCCTCAAAGTGGAGTTCCTGGAGTGTAGTGCCAAGGGTGG
ACGAGGGGATGCTGGCTCTGCGGACGTCCAGGACTTGGAGAAGTGGCTGGCCAAGATCGCCTGA
GGAGCATCGCTGACCACAAACCTTGGTCATGTGAGACTGATAAAGAGGCCGTGTCGTTGTTTGT
AAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001013270	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH98951	(Get FASTA)	NCBI Sequence Viewer
	AAP92615	(Get FASTA)	NCBI Sequence Viewer
	AAP92631	(Get FASTA)	NCBI Sequence Viewer
	AAP92642	(Get FASTA)	NCBI Sequence Viewer
	EDL77390	(Get FASTA)	NCBI Sequence Viewer
	EDL77391	(Get FASTA)	NCBI Sequence Viewer
	EDL77392	(Get FASTA)	NCBI Sequence Viewer
	Q4FZX7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001013270 ⟸ NM_001013252

- UniProtKB:

Q4FZX7 (UniProtKB/Swiss-Prot), A6I2I7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASANTRRVGDGAGGAFQPYLDSLRQELQQRDPTLLSVAVAVLAVLLTLVFWKFIWSRKSSQRA
VLFVGLCDSGKTLLFVRLLTGQYRDTQTSITDSSAIYKVNNNRGNSLTLIDLPGHESLRLQFLD
RFKSSARAVVFVVDSATFQREVKDVAEFLYQVLIDSMALKNTPAFLVACNKQDIAMAKSAKLIQ
QQLEKELNTLRVTRSAAPSTLDSSSTAPAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDAGSA
DVQDLEKWLAKIA

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Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4FZX7-F1-model_v2	AlphaFold	Q4FZX7	1-269	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304698	AgrOrtholog
BioCyc Gene	G2FUF-29333	BioCyc
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7324816	IMAGE-MGC_LOAD
InterPro	P-loop_NTPase	UniProtKB/Swiss-Prot
	Small_GTPase_ARF	UniProtKB/Swiss-Prot
	SRP_receptor_beta_su	UniProtKB/Swiss-Prot
KEGG Report	rno:300965	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:114584	IMAGE-MGC_LOAD
NCBI Gene	300965	ENTREZGENE
PANTHER	ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1	UniProtKB/Swiss-Prot
	ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1	UniProtKB/Swiss-Prot
Pfam	SRPRB	UniProtKB/Swiss-Prot
PhenoGen	Srprb	PhenoGen
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot
UniProt	A6I2I5_RAT	UniProtKB/TrEMBL
	A6I2I6_RAT	UniProtKB/TrEMBL
	A6I2I7	ENTREZGENE, UniProtKB/TrEMBL
	Q4FZX7	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-04	Srprb	SRP receptor subunit beta	Srprb	SRP receptor beta subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-11-25	Srprb	SRP receptor beta subunit	Srprb	signal recognition particle receptor, B subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Srprb	signal recognition particle receptor, B subunit	Srprb_predicted	signal recognition particle receptor, B subunit (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Srprb_predicted	signal recognition particle receptor, B subunit (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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