Aste1 (asteroid structure-specific endonuclease 1) - Rat Genome Database

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Gene: Aste1 (asteroid structure-specific endonuclease 1) Rattus norvegicus
Analyze
Symbol: Aste1
Name: asteroid structure-specific endonuclease 1 (Ensembl:asteroid homolog 1)
RGD ID: 1304643
Description: Predicted to enable 3' overhang single-stranded DNA endodeoxyribonuclease activity. Predicted to be involved in double-strand break repair via homologous recombination and double-strand break repair via nonhomologous end joining. Human ortholog(s) of this gene implicated in Lynch syndrome and mismatch repair cancer syndrome. Orthologous to human ASTE1 (asteroid homolog 1); INTERACTS WITH 17beta-estradiol; benzo[a]pyrene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: asteroid homolog 1; asteroid homolog 1 (Drosophila); LOC363130; RGD1304643; similar to asteroid CG4426-PA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88114,905,349 - 114,923,775 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8114,905,266 - 114,923,105 (+)EnsemblGRCr8
mRatBN7.28106,026,570 - 106,044,694 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8106,026,515 - 106,044,430 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8111,655,122 - 111,665,629 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08109,854,373 - 109,864,880 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08107,697,077 - 107,707,584 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08113,936,991 - 113,954,833 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8113,936,991 - 113,954,832 (+)Ensemblrn6Rnor6.0
Rnor_5.08113,322,462 - 113,342,413 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48110,501,422 - 110,516,965 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8105,359,298 - 105,369,824 (+)NCBICelera
RGSC_v3.18110,519,628 - 110,528,378 (+)NCBI
Cytogenetic Map8q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:12477932  


Genomics

Comparative Map Data
Aste1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88114,905,349 - 114,923,775 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8114,905,266 - 114,923,105 (+)EnsemblGRCr8
mRatBN7.28106,026,570 - 106,044,694 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8106,026,515 - 106,044,430 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8111,655,122 - 111,665,629 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08109,854,373 - 109,864,880 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08107,697,077 - 107,707,584 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08113,936,991 - 113,954,833 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8113,936,991 - 113,954,832 (+)Ensemblrn6Rnor6.0
Rnor_5.08113,322,462 - 113,342,413 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48110,501,422 - 110,516,965 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8105,359,298 - 105,369,824 (+)NCBICelera
RGSC_v3.18110,519,628 - 110,528,378 (+)NCBI
Cytogenetic Map8q32NCBI
ASTE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383131,013,875 - 131,026,825 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3131,013,066 - 131,027,649 (-)Ensemblhg38GRCh38
GRCh373130,732,719 - 130,745,669 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363132,215,411 - 132,228,336 (-)NCBIBuild 36Build 36hg18NCBI36
Celera3129,157,968 - 129,170,892 (-)NCBICelera
Cytogenetic Map3q22.1NCBI
HuRef3128,116,859 - 128,129,780 (-)NCBIHuRef
CHM1_13130,696,245 - 130,709,170 (-)NCBICHM1_1
T2T-CHM13v2.03133,757,625 - 133,770,598 (-)NCBIT2T-CHM13v2.0
Aste1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399105,272,533 - 105,285,497 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9105,272,591 - 105,289,428 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm389105,395,294 - 105,408,299 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9105,395,392 - 105,412,229 (+)Ensemblmm10GRCm38
MGSCv379105,297,722 - 105,308,088 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369105,253,622 - 105,263,561 (+)NCBIMGSCv36mm8
Celera9104,992,887 - 105,003,207 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map956.61NCBI
Aste1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555017,373,713 - 7,383,092 (+)NCBIChiLan1.0ChiLan1.0
ASTE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22128,972,825 - 128,983,442 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13128,977,552 - 128,987,990 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03128,098,219 - 128,111,196 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13135,420,860 - 135,433,827 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3135,421,044 - 135,432,284 (-)EnsemblpanPan2panpan1.1
ASTE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12328,233,165 - 28,244,036 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2328,231,032 - 28,243,768 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2328,205,872 - 28,216,831 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02328,740,377 - 28,751,279 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.12328,436,690 - 28,447,583 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02328,495,397 - 28,506,344 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02328,745,248 - 28,756,015 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Aste1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560267,711,919 - 67,723,819 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365294,470,347 - 4,484,590 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365294,472,157 - 4,484,319 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASTE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl131,435,678 - 1,449,855 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1131,435,714 - 1,457,733 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2131,093,040 - 1,113,028 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ASTE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11559,178,704 - 59,186,556 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604132,196,726 - 32,205,222 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aste1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247306,998,274 - 7,008,828 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247306,998,194 - 7,010,284 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Aste1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1896,689,515 - 96,706,657 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Aste1
156 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:76
Interacting mature miRNAs:81
Transcripts:ENSRNOT00000017743
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)897492344116428905Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
631217Activ1Activity QTL 115.9voluntary movement trait (VT:0003491)number of photobeam interruptions in an experimental apparatus (CMO:0001517)8111249511117802327Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
AV006403  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28106,036,772 - 106,036,898 (+)MAPPERmRatBN7.2
Rnor_6.08113,947,194 - 113,947,319NCBIRnor6.0
Rnor_5.08113,337,344 - 113,337,469UniSTSRnor5.0
Rnor_5.08113,332,731 - 113,332,856UniSTSRnor5.0
RGSC_v3.48110,508,728 - 110,508,853UniSTSRGSC3.4
Celera8105,369,500 - 105,369,625UniSTS
Cytogenetic Map8q32UniSTS
RH131266  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28106,043,610 - 106,043,793 (+)MAPPERmRatBN7.2
Rnor_6.08113,954,013 - 113,954,195NCBIRnor6.0
Rnor_5.08113,341,131 - 113,341,313UniSTSRnor5.0
RGSC_v3.48110,516,146 - 110,516,328UniSTSRGSC3.4
Celera8105,376,337 - 105,376,519UniSTS
RH 3.4 Map81150.5UniSTS
Cytogenetic Map8q32UniSTS
BF390084  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28106,034,833 - 106,034,986 (+)MAPPERmRatBN7.2
Rnor_6.08113,945,255 - 113,945,407NCBIRnor6.0
Rnor_5.08113,330,792 - 113,330,944UniSTSRnor5.0
RGSC_v3.48110,506,791 - 110,506,943UniSTSRGSC3.4
Celera8105,367,562 - 105,367,714UniSTS
RH 3.4 Map81152.7UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001040156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC083913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ193960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000017743   ⟹   ENSRNOP00000017743
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8114,905,266 - 114,915,870 (+)Ensembl
mRatBN7.2 Ensembl8106,028,308 - 106,037,091 (+)Ensembl
Rnor_6.0 Ensembl8113,936,991 - 113,947,512 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000065794   ⟹   ENSRNOP00000074497
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8114,905,298 - 114,923,105 (+)Ensembl
mRatBN7.2 Ensembl8106,026,570 - 106,044,430 (+)Ensembl
Rnor_6.0 Ensembl8113,938,626 - 113,953,917 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079562   ⟹   ENSRNOP00000070732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8114,911,869 - 114,923,105 (+)Ensembl
mRatBN7.2 Ensembl8106,029,465 - 106,044,430 (+)Ensembl
Rnor_6.0 Ensembl8113,939,886 - 113,954,832 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102495   ⟹   ENSRNOP00000091984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8106,026,515 - 106,037,091 (+)Ensembl
RefSeq Acc Id: NM_001040156   ⟹   NP_001035246
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,905,349 - 114,915,876 (+)NCBI
mRatBN7.28106,026,570 - 106,037,097 (+)NCBI
Rnor_6.08113,936,991 - 113,947,518 (+)NCBI
Rnor_5.08113,322,462 - 113,342,413 (+)NCBI
RGSC_v3.48110,501,422 - 110,516,965 (+)RGD
Celera8105,359,298 - 105,369,824 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039081782   ⟹   XP_038937710
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,906,996 - 114,913,834 (+)NCBI
mRatBN7.28106,026,656 - 106,035,055 (+)NCBI
RefSeq Acc Id: XM_063265809   ⟹   XP_063121879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,906,996 - 114,923,775 (+)NCBI
RefSeq Acc Id: XM_063265810   ⟹   XP_063121880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,906,996 - 114,913,834 (+)NCBI
RefSeq Acc Id: XM_063265811   ⟹   XP_063121881
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,906,996 - 114,913,834 (+)NCBI
RefSeq Acc Id: XM_063265812   ⟹   XP_063121882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,906,996 - 114,915,766 (+)NCBI
RefSeq Acc Id: XM_063265813   ⟹   XP_063121883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,907,003 - 114,915,766 (+)NCBI
RefSeq Acc Id: XM_063265814   ⟹   XP_063121884
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,906,996 - 114,923,775 (+)NCBI
RefSeq Acc Id: XM_063265815   ⟹   XP_063121885
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,906,999 - 114,915,766 (+)NCBI
RefSeq Acc Id: XM_063265817   ⟹   XP_063121887
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88114,907,087 - 114,915,766 (+)NCBI
RefSeq Acc Id: NP_001035246   ⟸   NM_001040156
- UniProtKB: E9PU85 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070732   ⟸   ENSRNOT00000079562
Ensembl Acc Id: ENSRNOP00000074497   ⟸   ENSRNOT00000065794
Ensembl Acc Id: ENSRNOP00000017743   ⟸   ENSRNOT00000017743
RefSeq Acc Id: XP_038937710   ⟸   XM_039081782
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000091984   ⟸   ENSRNOT00000102495
RefSeq Acc Id: XP_063121879   ⟸   XM_063265809
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K873 (UniProtKB/TrEMBL),   A6I2N2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121884   ⟸   XM_063265814
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063121882   ⟸   XM_063265812
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063121880   ⟸   XM_063265810
- Peptide Label: isoform X2
- UniProtKB: A6I2N2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121881   ⟸   XM_063265811
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063121885   ⟸   XM_063265815
- Peptide Label: isoform X8
- UniProtKB: A0A8I6AEP3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121883   ⟸   XM_063265813
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063121887   ⟸   XM_063265817
- Peptide Label: isoform X9
- UniProtKB: E9PU85 (UniProtKB/TrEMBL)
Protein Domains
XPG N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PU85-F1-model_v2 AlphaFold E9PU85 1-672 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304643 AgrOrtholog
BioCyc Gene G2FUF-29273 BioCyc
Ensembl Genes ENSRNOG00000013059 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017743 ENTREZGENE
  ENSRNOT00000017743.7 UniProtKB/TrEMBL
  ENSRNOT00000065794 ENTREZGENE
  ENSRNOT00000065794.5 UniProtKB/TrEMBL
  ENSRNOT00000079562.3 UniProtKB/TrEMBL
Gene3D-CATH 5'-nuclease UniProtKB/TrEMBL
InterPro Asteroid UniProtKB/TrEMBL
  PIN_domain-like UniProtKB/TrEMBL
  XPG_DNA_repair_N UniProtKB/TrEMBL
NCBI Gene 363130 ENTREZGENE
PANTHER PROTEIN ASTEROID HOMOLOG 1 UniProtKB/TrEMBL
  PTHR15665 UniProtKB/TrEMBL
Pfam XPG_N UniProtKB/TrEMBL
PhenoGen Aste1 PhenoGen
RatGTEx ENSRNOG00000013059 RatGTEx
Superfamily-SCOP SSF88723 UniProtKB/TrEMBL
UniProt A0A0G2K873 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AEP3 ENTREZGENE
  A6I2N2 ENTREZGENE, UniProtKB/TrEMBL
  E9PU85 ENTREZGENE, UniProtKB/TrEMBL
  Q5XHY6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Aste1  asteroid structure-specific endonuclease 1  Aste1  asteroid homolog 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-06-12 Aste1  asteroid homolog 1  Aste1  asteroid homolog 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Aste1  asteroid homolog 1 (Drosophila)  RGD1304643  similar to asteroid CG4426-PA  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1304643  similar to asteroid CG4426-PA  RGD1304643_predicted  similar to asteroid CG4426-PA (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1304643_predicted  similar to asteroid CG4426-PA (predicted)  LOC363130_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC363130_predicted  similar to asteroid CG4426-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL