Aste1 (asteroid homolog 1) - Rat Genome Database

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Gene: Aste1 (asteroid homolog 1) Heterocephalus glaber
Analyze
Symbol: Aste1
Name: asteroid homolog 1
RGD ID: 18929363
Description: ENCODES a protein that exhibits nuclease activity (inferred); ASSOCIATED WITH alkaptonuria (ortholog); Lynch syndrome (ortholog); mismatch repair cancer syndrome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein asteroid homolog 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247306,998,274 - 7,008,828 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247306,998,194 - 7,010,284 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Aste1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247306,998,274 - 7,008,828 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247306,998,194 - 7,010,284 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ASTE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383131,013,875 - 131,026,825 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3131,013,875 - 131,027,649 (-)EnsemblGRCh38hg38GRCh38
GRCh373130,732,719 - 130,745,669 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363132,215,411 - 132,228,336 (-)NCBINCBI36Build 36hg18NCBI36
Celera3129,157,968 - 129,170,892 (-)NCBICelera
Cytogenetic Map3q22.1NCBI
HuRef3128,116,859 - 128,129,780 (-)NCBIHuRef
CHM1_13130,696,245 - 130,709,170 (-)NCBICHM1_1
T2T-CHM13v2.03133,757,625 - 133,770,598 (-)NCBIT2T-CHM13v2.0
Aste1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399105,272,533 - 105,285,497 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9105,272,591 - 105,289,428 (+)EnsemblGRCm39 Ensembl
GRCm389105,395,294 - 105,408,299 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9105,395,392 - 105,412,229 (+)EnsemblGRCm38mm10GRCm38
MGSCv379105,297,722 - 105,308,088 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369105,253,622 - 105,263,561 (+)NCBIMGSCv36mm8
Celera9104,992,887 - 105,003,207 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map956.61NCBI
Aste1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88114,905,349 - 114,923,775 (+)NCBIGRCr8
mRatBN7.28106,026,570 - 106,044,694 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8106,026,515 - 106,044,430 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8111,655,122 - 111,665,629 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08109,854,373 - 109,864,880 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08107,697,077 - 107,707,584 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08113,936,991 - 113,954,833 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8113,936,991 - 113,954,832 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08113,322,462 - 113,342,413 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48110,501,422 - 110,516,965 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18110,519,628 - 110,528,378 (+)NCBI
Celera8105,359,298 - 105,369,824 (+)NCBICelera
Cytogenetic Map8q32NCBI
Aste1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555017,373,713 - 7,383,092 (+)NCBIChiLan1.0ChiLan1.0
ASTE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22128,972,825 - 128,983,442 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13128,977,552 - 128,987,990 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03128,098,219 - 128,111,196 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13135,420,860 - 135,433,827 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3135,421,044 - 135,432,284 (-)Ensemblpanpan1.1panPan2
ASTE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12328,233,165 - 28,244,036 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2328,231,032 - 28,243,768 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2328,205,872 - 28,216,831 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02328,740,377 - 28,751,279 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12328,436,690 - 28,447,583 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02328,495,397 - 28,506,344 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02328,745,248 - 28,756,015 (-)NCBIUU_Cfam_GSD_1.0
Aste1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560267,711,919 - 67,723,819 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365294,470,347 - 4,484,590 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365294,472,157 - 4,484,319 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASTE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl131,435,678 - 1,449,855 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1131,435,714 - 1,457,733 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2131,093,040 - 1,113,028 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ASTE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11559,178,704 - 59,186,556 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604132,196,726 - 32,205,222 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000023844   ⟹   ENSHGLP00000023626
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247306,998,274 - 7,008,828 (-)Ensembl
RefSeq Acc Id: XM_021242549   ⟹   XP_021098208
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247306,998,194 - 7,010,284 (-)NCBI
RefSeq Acc Id: XM_021242596   ⟹   XP_021098255
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247306,998,194 - 7,010,219 (-)NCBI
RefSeq Acc Id: XM_021242629   ⟹   XP_021098288
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247306,998,194 - 7,010,219 (-)NCBI
RefSeq Acc Id: XM_021242649   ⟹   XP_021098308
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247306,998,194 - 7,009,912 (-)NCBI
RefSeq Acc Id: XM_021242680   ⟹   XP_021098339
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247306,998,194 - 7,010,219 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021098208 (Get FASTA)   NCBI Sequence Viewer  
  XP_021098255 (Get FASTA)   NCBI Sequence Viewer  
  XP_021098288 (Get FASTA)   NCBI Sequence Viewer  
  XP_021098308 (Get FASTA)   NCBI Sequence Viewer  
  XP_021098339 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000023626
Reference Protein Sequences
RefSeq Acc Id: XP_021098208   ⟸   XM_021242549
- Peptide Label: isoform X1
- UniProtKB: G5AM68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098339   ⟸   XM_021242680
- Peptide Label: isoform X2
- UniProtKB: G5AM68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098288   ⟸   XM_021242629
- Peptide Label: isoform X2
- UniProtKB: G5AM68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098255   ⟸   XM_021242596
- Peptide Label: isoform X2
- UniProtKB: G5AM68 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098308   ⟸   XM_021242649
- Peptide Label: isoform X2
- UniProtKB: G5AM68 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000023626   ⟸   ENSHGLT00000023844


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016853 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000023844 ENTREZGENE
Gene3D-CATH 5'-nuclease UniProtKB/TrEMBL
InterPro Asteroid UniProtKB/TrEMBL
  PIN-like_dom_sf UniProtKB/TrEMBL
  XPG_DNA_repair_N UniProtKB/TrEMBL
NCBI Gene Aste1 ENTREZGENE
PANTHER ASTEROID PROTEIN UniProtKB/TrEMBL
  PROTEIN ASTEROID HOMOLOG 1 UniProtKB/TrEMBL
Pfam XPG_N UniProtKB/TrEMBL
Superfamily-SCOP PIN domain-like UniProtKB/TrEMBL
UniProt G5AM68 ENTREZGENE, UniProtKB/TrEMBL