Ufd1 (ubiquitin recognition factor in ER associated degradation 1) - Rat Genome Database

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Gene: Ufd1 (ubiquitin recognition factor in ER associated degradation 1) Chinchilla lanigera
Analyze
Symbol: Ufd1
Name: ubiquitin recognition factor in ER associated degradation 1
RGD ID: 8995624
Description: ENCODES a protein that exhibits ATPase binding (ortholog); K48-linked polyubiquitin modification-dependent protein binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to misfolded protein (ortholog); ERAD pathway (ortholog); negative regulation of RIG-I signaling pathway (ortholog); PARTICIPATES IN schizophrenia pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 22q11.2 deletion syndrome, distal (ortholog); FOUND IN cytoplasm (ortholog); UFD1-NPL4 complex (ortholog); VCP-NPL4-UFD1 AAA ATPase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin fusion degradation 1 like; ubiquitin fusion degradation 1 like (yeast); ubiquitin fusion degradation protein 1 homolog; Ufd1l
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544218,548,545 - 18,569,366 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544218,548,545 - 18,568,989 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ufd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544218,548,545 - 18,569,366 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544218,548,545 - 18,568,989 (+)NCBIChiLan1.0ChiLan1.0
UFD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,449,911 - 19,479,193 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,449,911 - 19,479,202 (-)EnsemblGRCh38hg38GRCh38
GRCh372219,437,434 - 19,466,716 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,817,701 - 17,846,726 (-)NCBINCBI36Build 36hg18NCBI36
Build 342217,812,394 - 17,841,280NCBI
Celera223,289,721 - 3,318,998 (-)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef223,058,276 - 3,087,551 (-)NCBIHuRef
CHM1_12219,437,034 - 19,466,309 (-)NCBICHM1_1
T2T-CHM13v2.02219,826,739 - 19,856,026 (-)NCBIT2T-CHM13v2.0
Ufd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,630,486 - 18,654,011 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,630,529 - 18,654,011 (+)EnsemblGRCm39 Ensembl
GRCm381618,811,736 - 18,835,261 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,811,779 - 18,835,261 (+)EnsemblGRCm38mm10GRCm38
MGSCv371618,812,387 - 18,835,354 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361618,725,889 - 18,748,818 (+)NCBIMGSCv36mm8
Celera1619,386,351 - 19,409,318 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.65NCBI
Ufd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81195,665,971 - 95,689,423 (-)NCBIGRCr8
mRatBN7.21182,161,618 - 82,185,107 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,161,619 - 82,185,087 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,890,505 - 90,916,772 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01183,551,725 - 83,577,992 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,604,993 - 82,631,260 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01186,304,836 - 86,328,478 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,304,815 - 86,328,469 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01189,406,802 - 89,430,903 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1180,942,108 - 80,965,579 (-)NCBICelera
Cytogenetic Map11q23NCBI
UFD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22329,074,863 - 29,104,101 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12231,622,567 - 31,651,807 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0222,209,590 - 2,238,449 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12217,885,073 - 17,913,506 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2217,885,073 - 17,913,506 (-)Ensemblpanpan1.1panPan2
UFD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,739,062 - 29,763,315 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,739,153 - 29,763,313 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2629,694,170 - 29,719,526 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02631,140,571 - 31,165,953 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2631,140,615 - 31,165,955 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12629,187,885 - 29,213,241 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,813,584 - 28,838,650 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,900,203 - 29,925,588 (+)NCBIUU_Cfam_GSD_1.0
Ufd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118139,333,947 - 139,358,936 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366193,395,687 - 3,419,472 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366193,395,130 - 3,419,704 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UFD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,113,713 - 51,133,072 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,113,858 - 51,132,820 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,680,894 - 54,689,406 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UFD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1196,275,834 - 6,305,940 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl196,275,844 - 6,308,035 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666085627,687 - 657,884 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ufd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624747110,090 - 132,097 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624747110,090 - 132,145 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000022464   ⟹   ENSCLAP00000022259
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544218,548,545 - 18,569,366 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000022465   ⟹   ENSCLAP00000022260
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544218,551,316 - 18,568,237 (+)Ensembl
RefSeq Acc Id: XM_005391776   ⟹   XP_005391833
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544218,548,545 - 18,568,989 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005391833 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000022259
  ENSCLAP00000022259.1
  ENSCLAP00000022260.1
Reference Protein Sequences
RefSeq Acc Id: XP_005391833   ⟸   XM_005391776
- UniProtKB: A0A8C2W4U8 (UniProtKB/TrEMBL),   A0A8C2W0L6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000022260   ⟸   ENSCLAT00000022465
RefSeq Acc Id: ENSCLAP00000022259   ⟸   ENSCLAT00000022464


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015265 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000022464 ENTREZGENE
  ENSCLAT00000022464.1 UniProtKB/TrEMBL
  ENSCLAT00000022465.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.40.50 UniProtKB/TrEMBL
  3.10.330.10 UniProtKB/TrEMBL
InterPro Ufd1-like UniProtKB/TrEMBL
  Ufd1-like_Nn UniProtKB/TrEMBL
NCBI Gene Ufd1l ENTREZGENE
PANTHER PTHR12555 UniProtKB/TrEMBL
  UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1 UniProtKB/TrEMBL
Pfam UFD1 UniProtKB/TrEMBL
UniProt A0A8C2W0L6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2W4U8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-02-28 Ufd1  ubiquitin recognition factor in ER associated degradation 1  Ufd1l  ubiquitin fusion degradation 1 like (yeast)  Symbol and/or name change 5135510 APPROVED