Ufd1 (ubiquitin recognition factor in ER associated degradation 1) - Rat Genome Database

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Gene: Ufd1 (ubiquitin recognition factor in ER associated degradation 1) Heterocephalus glaber
Analyze
Symbol: Ufd1 (Ensembl: UFD1L)
Name: ubiquitin recognition factor in ER associated degradation 1
RGD ID: 18920226
Description: ENCODES a protein that exhibits ATPase binding (ortholog); K48-linked polyubiquitin modification-dependent protein binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to misfolded protein (ortholog); ERAD pathway (ortholog); negative regulation of RIG-I signaling pathway (ortholog); PARTICIPATES IN schizophrenia pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 22q11.2 deletion syndrome, distal (ortholog); FOUND IN cytoplasm (ortholog); UFD1-NPL4 complex (ortholog); VCP-NPL4-UFD1 AAA ATPase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin fusion degradation 1 like; ubiquitin fusion degradation protein 1 homolog; ubiquitin recognition factor in ER-associated degradation protein 1; Ufd1l
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624747110,090 - 132,097 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624747110,090 - 132,145 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ufd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624747110,090 - 132,097 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624747110,090 - 132,145 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
UFD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,449,911 - 19,479,193 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,449,911 - 19,479,202 (-)EnsemblGRCh38hg38GRCh38
GRCh372219,437,434 - 19,466,716 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,817,701 - 17,846,726 (-)NCBINCBI36Build 36hg18NCBI36
Build 342217,812,394 - 17,841,280NCBI
Celera223,289,721 - 3,318,998 (-)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef223,058,276 - 3,087,551 (-)NCBIHuRef
CHM1_12219,437,034 - 19,466,309 (-)NCBICHM1_1
T2T-CHM13v2.02219,826,739 - 19,856,026 (-)NCBIT2T-CHM13v2.0
Ufd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,630,486 - 18,654,011 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,630,529 - 18,654,011 (+)EnsemblGRCm39 Ensembl
GRCm381618,811,736 - 18,835,261 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,811,779 - 18,835,261 (+)EnsemblGRCm38mm10GRCm38
MGSCv371618,812,387 - 18,835,354 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361618,725,889 - 18,748,818 (+)NCBIMGSCv36mm8
Celera1619,386,351 - 19,409,318 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.65NCBI
Ufd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81195,665,971 - 95,689,423 (-)NCBIGRCr8
mRatBN7.21182,161,618 - 82,185,107 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,161,619 - 82,185,087 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,890,505 - 90,916,772 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01183,551,725 - 83,577,992 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,604,993 - 82,631,260 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01186,304,836 - 86,328,478 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,304,815 - 86,328,469 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01189,406,802 - 89,430,903 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1180,942,108 - 80,965,579 (-)NCBICelera
Cytogenetic Map11q23NCBI
Ufd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544218,548,545 - 18,569,366 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544218,548,545 - 18,568,989 (+)NCBIChiLan1.0ChiLan1.0
UFD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22329,074,863 - 29,104,101 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12231,622,567 - 31,651,807 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0222,209,590 - 2,238,449 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12217,885,073 - 17,913,506 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2217,885,073 - 17,913,506 (-)Ensemblpanpan1.1panPan2
UFD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,739,062 - 29,763,315 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,739,153 - 29,763,313 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2629,694,170 - 29,719,526 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02631,140,571 - 31,165,953 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2631,140,615 - 31,165,955 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12629,187,885 - 29,213,241 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,813,584 - 28,838,650 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,900,203 - 29,925,588 (+)NCBIUU_Cfam_GSD_1.0
Ufd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118139,333,947 - 139,358,936 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366193,395,687 - 3,419,472 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366193,395,130 - 3,419,704 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UFD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,113,713 - 51,133,072 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,113,858 - 51,132,820 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,680,894 - 54,689,406 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UFD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1196,275,834 - 6,305,940 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl196,275,844 - 6,308,035 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666085627,687 - 657,884 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000020966   ⟹   ENSHGLP00000020763
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624747110,090 - 132,097 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000020967   ⟹   ENSHGLP00000020764
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624747110,139 - 129,000 (-)Ensembl
RefSeq Acc Id: XM_004843247   ⟹   XP_004843304
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624747110,090 - 132,145 (-)NCBI
RefSeq Acc Id: XM_004843248   ⟹   XP_004843305
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624747110,090 - 132,104 (-)NCBI
RefSeq Acc Id: XM_021257044   ⟹   XP_021112703
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624747110,090 - 132,111 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004843304 (Get FASTA)   NCBI Sequence Viewer  
  XP_004843305 (Get FASTA)   NCBI Sequence Viewer  
  XP_021112703 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020763
  ENSHGLP00100016453
GenBank Protein JAO01672 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004843304   ⟸   XM_004843247
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JBJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112703   ⟸   XM_021257044
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004843305   ⟸   XM_004843248
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000020764   ⟸   ENSHGLT00000020967
RefSeq Acc Id: ENSHGLP00000020763   ⟸   ENSHGLT00000020966


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014850 Ensembl, ENTREZGENE
  ENSHGLG00100012147 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000020966 ENTREZGENE
  ENSHGLT00100016632 UniProtKB/TrEMBL
Gene3D-CATH 2.40.40.50 UniProtKB/TrEMBL
  3.10.330.10 UniProtKB/TrEMBL
InterPro Ufd1-like UniProtKB/TrEMBL
  Ufd1-like_Nn UniProtKB/TrEMBL
KEGG Report hgl:101714351 UniProtKB/TrEMBL
NCBI Gene Ufd1 ENTREZGENE
PANTHER PTHR12555 UniProtKB/TrEMBL
  UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1 UniProtKB/TrEMBL
Pfam UFD1 UniProtKB/TrEMBL
UniProt A0A0P6JBJ5 ENTREZGENE, UniProtKB/TrEMBL