Grpel1 (GrpE like 1, mitochondrial)

Gene: Grpel1 (GrpE like 1, mitochondrial) Chinchilla lanigera

Analyze

Symbol:

Grpel1

Name:

GrpE like 1, mitochondrial

RGD ID:

8751807

Description:

ENCODES a protein that exhibits ATPase activator activity (ortholog); ATPase binding (ortholog); identical protein binding (ortholog); PARTICIPATES IN presequence pathway of mitochondrial protein import; ASSOCIATED WITH human immunodeficiency virus infectious disease (ortholog); middle cerebral artery infarction (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

grpE protein homolog 1, mitochondrial; GrpE-like 1, mitochondrial (E. coli)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955514	3,459,774 - 3,467,279 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955514	3,459,774 - 3,467,279 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

human immunodeficiency virus infectious disease (ISO)

middle cerebral artery infarction (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

mitochondrial matrix (ISO)

mitochondrion (ISO)

nucleoplasm (ISO)

Molecular Function

ATPase activator activity (ISO)

ATPase binding (ISO)

identical protein binding (ISO)

protein binding (ISO)

unfolded protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

presequence pathway of mitochondrial protein import (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Grpel1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955514	3,459,774 - 3,467,279 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955514	3,459,774 - 3,467,279 (+)	NCBI	ChiLan1.0	ChiLan1.0

GRPEL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	7,058,895 - 7,068,064 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	7,058,671 - 7,068,085 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	7,060,622 - 7,069,791 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	7,112,681 - 7,120,701 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	7,179,851 - 7,187,872	NCBI
Celera	4	6,965,198 - 6,973,219 (-)	NCBI		Celera
Cytogenetic Map	4	p16.1	NCBI
HuRef	4	6,989,046 - 6,997,061 (-)	NCBI		HuRef
CHM1_1	4	7,060,163 - 7,068,180 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	7,030,735 - 7,039,901 (-)	NCBI		T2T-CHM13v2.0

Grpel1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	36,622,529 - 36,631,421 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	36,622,342 - 36,631,424 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	36,465,185 - 36,474,077 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	36,464,998 - 36,474,080 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	36,807,834 - 36,816,726 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	36,782,280 - 36,791,172 (+)	NCBI		MGSCv36	mm8
Celera	5	33,946,160 - 33,955,052 (+)	NCBI		Celera
Cytogenetic Map	5	B3	NCBI
cM Map	5	19.14	NCBI

Grpel1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	78,517,049 - 78,522,868 (-)	NCBI		GRCr8
mRatBN7.2	14	74,292,023 - 74,298,243 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	74,292,023 - 74,298,200 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	78,734,419 - 78,740,226 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	79,975,292 - 79,981,099 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	76,420,265 - 76,426,072 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	79,458,951 - 79,464,782 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	79,458,963 - 79,464,770 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	79,097,953 - 79,103,777 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	79,873,191 - 79,878,998 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	79,875,225 - 79,881,387 (-)	NCBI
Celera	14	73,230,590 - 73,236,397 (-)	NCBI		Celera
Cytogenetic Map	14	q21	NCBI

GRPEL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	7,326,364 - 7,334,615 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	7,255,405 - 7,263,644 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	4	7,126,043 - 7,135,388 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	7,126,043 - 7,135,388 (-)	Ensembl	panpan1.1		panPan2

GRPEL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	59,124,116 - 59,131,541 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	59,124,613 - 59,131,977 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	61,770,979 - 61,778,423 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	59,595,959 - 59,603,388 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	59,595,274 - 59,603,595 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	59,093,027 - 59,100,454 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	59,294,915 - 59,302,364 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	59,649,262 - 59,656,689 (-)	NCBI		UU_Cfam_GSD_1.0

Grpel1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	65,181,864 - 65,189,477 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936477	18,880,736 - 18,891,110 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936477	18,883,556 - 18,891,108 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GRPEL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	8	3,797,310 - 3,813,725 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	3,397,261 - 3,413,692 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GRPEL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	27	43,173,664 - 43,182,015 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	27	43,174,467 - 43,181,783 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	90,028,597 - 90,036,905 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Grpel1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624755	23,270,910 - 23,280,264 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624755	23,273,253 - 23,280,328 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005408795	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01067096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01061487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000021921 ⟹ ENSCLAP00000021718

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955514	3,459,774 - 3,467,279 (+)	Ensembl

RefSeq Acc Id:

XM_005408795 ⟹ XP_005408852

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955514	3,459,774 - 3,467,279 (+)	NCBI

Sequence:

show sequence

ACGCAAGCCCAATGCGTGCGAAGTGACGGCGGCGACGGCAGTAGTGATGGCGGCTCGCTGCGTA
AGGCTGGCGCGGCGCAGTCTCCCGGCTTTGTCGTTGTGTCTCAGGCCCTCCCCGAGGCTGCTGT
GCACCGCCACAAAGCAGAAGAGCAATGGCCAGGGCCTGGAGGAGGACACGCGGCCCAGCGAGCC
AAAGCCCGAGCCTCCCGCCACGGACAAGGTCCTGCTAGAAGAGAAGGGCCGGTTGGAGGAGCAG
CTCAGAGAGACCGTGGAGAAATACAAGCGAGCTCTGGCAGATACTGAGAACTTGCGGCAGAGAA
GCCAGAAACTCATAGAGGAGGCCAAGCTCTATGGCATCCAGGGCTTCTGCAAGGACCTGCTGGA
GGTGGCGGACATTCTGGAGAAGGCCACCCAGAGCGTCCCGAAAGAAGCGATCCGAGATGAGAAC
CCTCACCTGAAGAGCCTGTACGAGGGGCTGGTGATGACCGAGGTACAGATGCAGAAGGTGTTCA
CGAAGCACGGCCTGCTCAGGCTGGACCCTGTTGGAGCCAAGTTTGACCCCTACGAACACGAGGC
CTTGTTCCACACGCCCGTGGAGGGAAAGGAGCCAGGCACCGTGGCGCTGGTCAGCAAGGTGGGC
TACAAGCTGCACGGGCGCACGCTGCGGCCTGCACTGGTGGGGGTAGCGAAGGAAGCCTAGCTGT
GCCACGGCGCTGGGTCTGGTGTCCTTCGCTGTAACTCCTGAAAGGCGGCATCACCTTGTCTCCT
GCGTGTGCACCTGTGCCCTGTGCCCGGACTGGCCGGAAGCAGGAGAGGGTGGCTGAGCAGGGGC
AGGGCGGCGCCCACTCAGGCTCAGGAACTGACTCAGCATCTGCTCACGGCTGCTCTGTGCCACC
ACGCACTCATTCTGCACACTGAGGGCCAGGGCTGTGGGGGCCTCTGTCCCAAGTAGCGCTGTAT
CCACTCAAATTCCGGTGATTGCAAAGTATTTTGAACAAATAAAAGGTCTCTGGGAATTCTGTTG
GCTGCCTGGCCACACCCTTCTGCACCTTGTCGCCCACGCTGCAGCCCCAAGTCACTGGCGCCCC
TGCCCACCACGCGCTTCCCTGCTGAGGAAAGGACCCCTTTCTCGTGCTAAAAGCAATGTGCACT
GCTGTTTGAGAAGAGTTCGGGTGTAACTGGCGTCTGCCTTTGGCTCCTCTGCGGAGACAGGAAG
TGGGTGTGTGAACCGTGAGGCGCGTACCTTTACCTTGCTGTGACTGGGTCTGCCCAAGTCAGTG
TCCCCCCTCCCCCCGGAGGCCCCGTTCTGTCCGTCACTGAGTTACCAACCACCTCAGAGTGTCC
CCTTAAGGTGGGCCTTCTCAGAATGCCTGCATGCTTGGGACGCTTCGCACGTCCATGCTCAATT
TTACATTTTTATTTAAGAGGGTTTGTTTCTTTTCCTACTTTCTGGTAACAGTTGAGTCCTTTGA
TGGAGACCTTGAGCCCAAGGCCAAGCAGGACAGCTCCTCCATGTCCCACCGGGCCCTGAGCAGC
CTGGCACAGCCTTTTCCAGTGGAGCCAAGGCCACGGCGCCCTGTCTGGAGGAGGACTGGGCTGG
CACCAGGCCAGTCCTCATTTACATTTACATTGAGGACCTGGGGAGAGGGTTGAGCGAGCAGGCA
GCTGTCGCTAGTGAGAAATACAAGCCTCTGCCATCAGTGCAAGGACAGAAGGGCTGGGCGGTAA
GTGCACCTACTGCCCAAGGGTGGGGCAGAGCCCCTGGATCTCAGTAGCAGTTTAGAAAGATGCA
GTCGTGCCGTAATTAAAATCTTCCTTTGTTACTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005408852	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000021718
	ENSCLAP00000021718.1

RefSeq Acc Id:

XP_005408852 ⟸ XM_005408795

- UniProtKB:

A0A8C2W151 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAARCVRLARRSLPALSLCLRPSPRLLCTATKQKSNGQGLEEDTRPSEPKPEPPATDKVLLEEK
GRLEEQLRETVEKYKRALADTENLRQRSQKLIEEAKLYGIQGFCKDLLEVADILEKATQSVPKE
AIRDENPHLKSLYEGLVMTEVQMQKVFTKHGLLRLDPVGAKFDPYEHEALFHTPVEGKEPGTVA
LVSKVGYKLHGRTLRPALVGVAKEA

hide sequence

RefSeq Acc Id:

ENSCLAP00000021718 ⟸ ENSCLAT00000021921

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000014866	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000021921	ENTREZGENE
	ENSCLAT00000021921.1	UniProtKB/TrEMBL
Gene3D-CATH	2.30.22.10	UniProtKB/TrEMBL
	3.90.20.20	UniProtKB/TrEMBL
InterPro	GrpE	UniProtKB/TrEMBL
	GrpE_coiled_coil	UniProtKB/TrEMBL
	GrpE_head	UniProtKB/TrEMBL
NCBI Gene	Grpel1	ENTREZGENE
PANTHER	GRPE PROTEIN HOMOLOG 1, MITOCHONDRIAL	UniProtKB/TrEMBL
	PTHR21237	UniProtKB/TrEMBL
Pfam	GrpE	UniProtKB/TrEMBL
PRINTS	GRPEPROTEIN	UniProtKB/TrEMBL
PROSITE	GRPE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF51064	UniProtKB/TrEMBL
	SSF58014	UniProtKB/TrEMBL
UniProt	A0A8C2W151	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Grpel1	GrpE like 1, mitochondrial		GrpE-like 1, mitochondrial (E. coli)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

Send us a Message

Imported Disease Annotations - CTD

RGD Manual Annotations