Fxyd2 (FXYD domain-containing ion transport regulator 2) - Rat Genome Database

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Gene: Fxyd2 (FXYD domain-containing ion transport regulator 2) Mus musculus
Analyze
Symbol: Fxyd2
Name: FXYD domain-containing ion transport regulator 2
RGD ID: 736423
MGI Page MGI
Description: Enables sodium channel regulator activity. Predicted to be involved in inorganic cation transmembrane transport and negative regulation of cell population proliferation. Predicted to act upstream of or within potassium ion transport and sodium ion transport. Located in membrane. Is expressed in several structures, including early conceptus; gonad; intestine smooth muscle circular layer; metanephros; and spleen. Human ortholog(s) of this gene implicated in renal hypomagnesemia 2. Orthologous to human FXYD2 (FXYD domain containing ion transport regulator 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Atp1; Atp1g1; ATPase, Na+/K+ transporting, gamma 1 polypeptide; Na(+)/K(+) ATPase subunit gamma; sodium pump gamma chain; sodium/potassium-transporting ATPase gamma chain; sodium/potassium-transporting ATPase subunit gamma
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39945,311,007 - 45,321,576 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl945,310,967 - 45,321,576 (+)EnsemblGRCm39 Ensembl
GRCm38945,399,709 - 45,410,278 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl945,399,669 - 45,410,278 (+)EnsemblGRCm38mm10GRCm38
MGSCv37945,207,792 - 45,218,361 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36945,150,213 - 45,161,273 (+)NCBIMGSCv36mm8
Celera942,679,863 - 42,690,444 (+)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1-naphthyl isothiocyanate  (ISO)
2,2,2-tetramine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-deoxy-D-glucose  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucosamine  (ISO)
alpha-Zearalanol  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
barium(0)  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
Benzo[k]fluoranthene  (EXP)
beta-D-glucosamine  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
Deoxycorticosterone acetate  (ISO)
dicrotophos  (ISO)
diquat  (EXP)
diuron  (ISO)
ethylparaben  (ISO)
flavonoids  (ISO)
furan  (ISO)
glycine betaine  (ISO)
indole-3-methanol  (ISO)
inulin  (ISO)
leflunomide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methimazole  (ISO)
methyl methanesulfonate  (ISO)
N-nitrosodimethylamine  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (ISO)
potassium chloride  (ISO)
potassium dichromate  (EXP)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
Soman  (ISO)
spermidine  (ISO)
streptozocin  (ISO)
succimer  (EXP)
thioacetamide  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (EXP)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway   (ISO)
aldosterone signaling pathway  (IEA)
alfentanil pharmacodynamics pathway  (ISO)
amiloride pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
bendroflumethiazide pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bile acid transport pathway  (IEA)
bisoprolol pharmacodynamics pathway  (ISO)
bumetanide pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
chlorothiazide pharmacodynamics pathway  (ISO)
chlorthalidone pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
cystinuria pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
eplerenone pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
etacrynic acid pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
furosemide pharmacodynamics pathway  (ISO)
Hartnup disease pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrochlorothiazide pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydroflumethiazide pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
iminoglycinuria pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
lactose degradation pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
lysinuric protein intolerance pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
metolazone pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
spironolactone pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
torasemide pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)
trehalose degradation pathway  (ISO)
triamterene pharmacodynamics pathway  (ISO)
trichlormethiazide pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Dominant isolated renal magnesium loss is caused by misrouting of the Na(+),K(+)-ATPase gamma-subunit. Meij IC, etal., Nat Genet. 2000 Nov;26(3):265-6.
3. Molecular cloning and immunological characterization of the gamma polypeptide, a small protein associated with the Na,K-ATPase. Mercer RW, etal., J Cell Biol 1993 May;121(3):579-86.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression. Sweadner KJ and Rael E, Genomics 2000 Aug 15;68(1):41-56.
Additional References at PubMed
PMID:9396759   PMID:9600999   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11526196   PMID:12477932   PMID:15383396   PMID:15489334   PMID:15572522   PMID:15755730   PMID:16141072  
PMID:16141073   PMID:16403837   PMID:16602821   PMID:16804105   PMID:17079272   PMID:21267068   PMID:21677750   PMID:21873635   PMID:21947380   PMID:22253804   PMID:23344951   PMID:24688018  
PMID:25633594   PMID:26705335   PMID:26930384   PMID:32554809   PMID:36724234  


Genomics

Comparative Map Data
Fxyd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39945,311,007 - 45,321,576 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl945,310,967 - 45,321,576 (+)EnsemblGRCm39 Ensembl
GRCm38945,399,709 - 45,410,278 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl945,399,669 - 45,410,278 (+)EnsemblGRCm38mm10GRCm38
MGSCv37945,207,792 - 45,218,361 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36945,150,213 - 45,161,273 (+)NCBIMGSCv36mm8
Celera942,679,863 - 42,690,444 (+)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
FXYD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811117,820,057 - 117,828,089 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11117,800,844 - 117,828,698 (-)EnsemblGRCh38hg38GRCh38
GRCh3711117,690,772 - 117,698,804 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611117,196,000 - 117,204,017 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411117,195,999 - 117,204,017NCBI
Celera11114,848,637 - 114,856,650 (-)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11113,624,622 - 113,632,639 (-)NCBIHuRef
CHM1_111117,576,366 - 117,584,383 (-)NCBICHM1_1
T2T-CHM13v2.011117,836,469 - 117,844,497 (-)NCBIT2T-CHM13v2.0
Fxyd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8854,609,658 - 54,616,788 (+)NCBIGRCr8
mRatBN7.2845,712,901 - 45,720,032 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl845,712,903 - 45,720,203 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx851,214,299 - 51,220,774 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0849,493,069 - 49,499,544 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0847,357,158 - 47,363,642 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0849,710,334 - 49,717,492 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl849,710,477 - 49,716,955 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0848,336,046 - 48,343,177 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4848,379,075 - 48,385,553 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1848,387,840 - 48,394,319 (+)NCBI
Celera845,295,931 - 45,302,409 (+)NCBICelera
Cytogenetic Map8q22NCBI
Fxyd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541219,039,635 - 19,046,159 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541219,039,635 - 19,046,172 (-)NCBIChiLan1.0ChiLan1.0
FXYD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29118,521,067 - 118,537,885 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111119,626,001 - 119,642,808 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011112,654,774 - 112,666,630 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111116,587,226 - 116,598,684 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11116,587,226 - 116,595,197 (-)Ensemblpanpan1.1panPan2
FXYD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1515,812,335 - 15,824,552 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl515,815,969 - 15,823,057 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha515,865,958 - 15,873,046 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0515,753,844 - 15,766,049 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl515,757,465 - 15,764,547 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1515,895,521 - 15,902,609 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0515,798,806 - 15,805,894 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0515,840,422 - 15,847,514 (+)NCBIUU_Cfam_GSD_1.0
Fxyd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947100,035,374 - 100,039,684 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365422,956,785 - 2,963,506 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365422,956,784 - 2,961,076 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FXYD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1945,165,314 - 45,172,440 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2950,244,542 - 50,252,397 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FXYD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11109,187,301 - 109,199,729 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1109,186,886 - 109,198,267 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604316,860,199 - 16,864,880 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fxyd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478413,200,018 - 13,206,131 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478413,198,308 - 13,209,780 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fxyd2
424 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:185
Count of miRNA genes:163
Interacting mature miRNAs:172
Transcripts:ENSMUST00000041005
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300532Tbs2_mtuberculosis severity 2 (mouse)Not determined91236997046370114Mouse
10043917Obq37_mobesity QTL 37 (mouse)Not determined91339117547391175Mouse
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91541175149411890Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91541175149411890Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91541175149411890Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91541175149411890Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91574962749749627Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91574962749749627Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91574962749749627Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91601129650011296Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91601129650011296Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91670964150709641Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91697884050978943Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined91994340653943525Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92015336254153492Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92030619754306370Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92030619754306370Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92030619754306370Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92030619754306370Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92085274054852740Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92491129668907282Mouse
11532712Sluc39d_msusceptibility to lung cancer 39d (mouse)92558748559587581Mouse
11532696Sluc39c_msusceptibility to lung cancer 39c (mouse)92558748559587581Mouse
11532694Sluc39a_msusceptibility to lung cancer 39a (mouse)92558748559587581Mouse
11532695Sluc39b_msusceptibility to lung cancer 39b (mouse)92558748559587581Mouse
10043987Stheal13_msoft tissue heal 13 (mouse)Not determined92679642160796552Mouse
1300932Hdlq17_mHDL QTL 17 (mouse)Not determined92679642160796552Mouse
10043867Mtbcq9_mmultiple trait body composition QTL 9 (mouse)Not determined92679642160796552Mouse
10043878Adip20_madiposity 20 (mouse)Not determined92725119461251323Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92929292963293072Mouse
1301782Chol11_mcholesterol 11 (mouse)Not determined92929292963293072Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93005316464053277Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93073991564740021Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93243456366434857Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93245242166452546Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93251117266511421Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93288970266889836Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93311102567111140Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93397884073439255Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93503447869034599Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93503447869034599Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93503447869034599Mouse
10045613Rapop7_mradiation-induced apoptosis 6 (mouse)Not determined93673624349420511Mouse
1301501Lmr2_mleishmaniasis resistance 2 (mouse)Not determined93694340650111140Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93781952871819528Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93809957572099575Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93809957572099575Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93809957572099575Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93939988573399885Mouse
1558993Tdmq1_mtype 2 diabetes modifying QTL 1 (mouse)Not determined94041959451808670Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94041959474607925Mouse
11532693Sluc39_msusceptibility to lung cancer 39 (mouse)94064537448351476Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94080504774805204Mouse
12738415Lfibq8_mliver fibrosis QTL 8 (mouse)94140216245343743Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94348071477480860Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94348071477480860Mouse
13432191Actrse4_mactivity response to saline/ethanol 4 (mouse)94370321448603195Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94442817478428262Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001404664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_052823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_028499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA396010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC162176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI316264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY035583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY626243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY626244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY626245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU756853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA491597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB600439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB600958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X70060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000041005   ⟹   ENSMUSP00000035429
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,314,436 - 45,321,576 (+)Ensembl
GRCm38.p6 Ensembl945,403,138 - 45,410,278 (+)Ensembl
RefSeq Acc Id: ENSMUST00000213158
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,317,223 - 45,321,576 (+)Ensembl
GRCm38.p6 Ensembl945,405,925 - 45,410,278 (+)Ensembl
RefSeq Acc Id: ENSMUST00000213282
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,317,266 - 45,321,575 (+)Ensembl
GRCm38.p6 Ensembl945,405,968 - 45,410,277 (+)Ensembl
RefSeq Acc Id: ENSMUST00000213850   ⟹   ENSMUSP00000150521
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,313,421 - 45,314,615 (+)Ensembl
GRCm38.p6 Ensembl945,402,123 - 45,403,317 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214017
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,317,253 - 45,321,558 (+)Ensembl
GRCm38.p6 Ensembl945,405,955 - 45,410,260 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214245
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,317,430 - 45,319,882 (+)Ensembl
GRCm38.p6 Ensembl945,406,132 - 45,408,584 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214257   ⟹   ENSMUSP00000149343
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,313,954 - 45,319,442 (+)Ensembl
GRCm38.p6 Ensembl945,402,656 - 45,408,144 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214466   ⟹   ENSMUSP00000149140
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,314,512 - 45,321,576 (+)Ensembl
GRCm38.p6 Ensembl945,403,214 - 45,410,278 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214654
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,317,403 - 45,321,429 (+)Ensembl
GRCm38.p6 Ensembl945,406,105 - 45,410,131 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214680
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,310,967 - 45,321,517 (+)Ensembl
GRCm38.p6 Ensembl945,399,669 - 45,410,219 (+)Ensembl
RefSeq Acc Id: ENSMUST00000216289   ⟹   ENSMUSP00000150658
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,311,007 - 45,321,353 (+)Ensembl
GRCm38.p6 Ensembl945,399,709 - 45,410,055 (+)Ensembl
RefSeq Acc Id: ENSMUST00000216840
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,315,274 - 45,321,018 (+)Ensembl
GRCm38.p6 Ensembl945,403,976 - 45,409,720 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217549
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl945,318,470 - 45,321,311 (+)Ensembl
GRCm38.p6 Ensembl945,407,172 - 45,410,013 (+)Ensembl
RefSeq Acc Id: NM_001404664   ⟹   NP_001391593
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39945,313,868 - 45,321,576 (+)NCBI
RefSeq Acc Id: NM_007503   ⟹   NP_031529
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39945,317,388 - 45,321,576 (+)NCBI
GRCm38945,406,090 - 45,410,278 (+)NCBI
MGSCv37945,207,792 - 45,218,361 (+)RGD
Celera942,679,863 - 42,690,444 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_052823   ⟹   NP_439888
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39945,314,479 - 45,321,576 (+)NCBI
GRCm38945,403,181 - 45,410,278 (+)NCBI
MGSCv37945,207,792 - 45,218,361 (+)RGD
Celera942,679,863 - 42,690,444 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_028499
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39945,311,007 - 45,321,576 (+)NCBI
GRCm38945,399,709 - 45,410,278 (+)NCBI
MGSCv37945,207,792 - 45,218,361 (+)RGD
Celera942,679,863 - 42,690,444 (+)RGD
cM Map9 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_439888   ⟸   NM_052823
- Peptide Label: isoform b
- UniProtKB: Q6ITT1 (UniProtKB/TrEMBL),   A0A1L1SUA9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_031529   ⟸   NM_007503
- Peptide Label: isoform a
- UniProtKB: Q923I3 (UniProtKB/Swiss-Prot),   Q923I2 (UniProtKB/Swiss-Prot),   Q923I4 (UniProtKB/Swiss-Prot),   Q04646 (UniProtKB/Swiss-Prot),   Q6ITT2 (UniProtKB/TrEMBL),   Q6ITT0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000150521   ⟸   ENSMUST00000213850
RefSeq Acc Id: ENSMUSP00000035429   ⟸   ENSMUST00000041005
RefSeq Acc Id: ENSMUSP00000150658   ⟸   ENSMUST00000216289
RefSeq Acc Id: ENSMUSP00000149343   ⟸   ENSMUST00000214257
RefSeq Acc Id: ENSMUSP00000149140   ⟸   ENSMUST00000214466
RefSeq Acc Id: NP_001391593   ⟸   NM_001404664
- Peptide Label: isoform b
- UniProtKB: Q6ITT1 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q04646-F1-model_v2 AlphaFold Q04646 1-70 view protein structure

Promoters
RGD ID:6844541
Promoter ID:MM_KWN:57183
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:NR_028499
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36945,207,471 - 45,207,971 (+)MPROMDB
RGD ID:6844539
Promoter ID:MM_KWN:57184
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Spleen
Transcripts:NM_052823
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36945,210,321 - 45,211,537 (+)MPROMDB
RGD ID:6844540
Promoter ID:MM_KWN:57185
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Kidney
Transcripts:ENSMUST00000085938,   NM_007503
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36945,213,711 - 45,214,211 (+)MPROMDB
RGD ID:6848414
Promoter ID:MM_ACW:50369
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:FXYD2.JSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36945,216,321 - 45,216,821 (+)MPROMDB
RGD ID:8669450
Promoter ID:EPDNEW_M12756
Type:initiation region
Name:Fxyd2_1
Description:Mus musculus FXYD domain-containing ion transport regulator 2, transcript variant a, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38945,403,202 - 45,403,262EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1195260 AgrOrtholog
Ensembl Genes ENSMUSG00000059412 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000041005 ENTREZGENE
  ENSMUST00000041005.6 UniProtKB/Swiss-Prot
  ENSMUST00000213850.2 UniProtKB/TrEMBL
  ENSMUST00000214257.2 UniProtKB/TrEMBL
  ENSMUST00000214466.2 UniProtKB/TrEMBL
  ENSMUST00000214680 ENTREZGENE
  ENSMUST00000216289.2 UniProtKB/TrEMBL
Gene3D-CATH Single helix bin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ATNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FXYD_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion-transport_regulator_FXYD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11936 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1195260 ENTREZGENE
NCBI Gene 11936 ENTREZGENE
PANTHER SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA UniProtKB/Swiss-Prot
  SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA UniProtKB/Swiss-Prot
  SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA UniProtKB/TrEMBL
  SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA UniProtKB/TrEMBL
Pfam ATP1G1_PLM_MAT8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fxyd2 PhenoGen
PROSITE FXYD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1L1SQP8_MOUSE UniProtKB/TrEMBL
  A0A1L1SR73_MOUSE UniProtKB/TrEMBL
  A0A1L1STY6_MOUSE UniProtKB/TrEMBL
  A0A1L1SUA9 ENTREZGENE, UniProtKB/TrEMBL
  ATNG_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q6ITT0 ENTREZGENE, UniProtKB/TrEMBL
  Q6ITT1 ENTREZGENE, UniProtKB/TrEMBL
  Q6ITT2 ENTREZGENE, UniProtKB/TrEMBL
  Q923I2 ENTREZGENE
  Q923I3 ENTREZGENE
  Q923I4 ENTREZGENE
UniProt Secondary Q923I2 UniProtKB/Swiss-Prot
  Q923I3 UniProtKB/Swiss-Prot
  Q923I4 UniProtKB/Swiss-Prot