Ei24 (EI24 autophagy associated transmembrane protein) - Rat Genome Database

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Gene: Ei24 (EI24 autophagy associated transmembrane protein) Heterocephalus glaber
Analyze
Symbol: Ei24
Name: EI24 autophagy associated transmembrane protein
RGD ID: 18936758
Description: ENCODES a protein that exhibits importin-alpha family protein binding (inferred); INVOLVED IN autophagy (ortholog); cellular response to UV-C (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); ASSOCIATED WITH Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog); holoprosencephaly 11 (ortholog); FOUND IN cytosol (inferred); endoplasmic reticulum (inferred); Golgi apparatus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: etoposide-induced protein 2.4 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249271,548,544 - 1,566,108 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ei24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249271,548,544 - 1,566,108 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
EI24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811125,569,477 - 125,584,684 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11125,569,280 - 125,584,684 (+)EnsemblGRCh38hg38GRCh38
GRCh3711125,439,373 - 125,454,579 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,944,508 - 124,959,785 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411124,944,507 - 124,959,784NCBI
Celera11122,599,610 - 122,614,886 (+)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11121,380,862 - 121,396,124 (+)NCBIHuRef
CHM1_111125,325,451 - 125,340,728 (+)NCBICHM1_1
T2T-CHM13v2.011125,598,125 - 125,613,333 (+)NCBIT2T-CHM13v2.0
Ei24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39936,690,449 - 36,708,630 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl936,690,455 - 36,708,689 (-)EnsemblGRCm39 Ensembl
GRCm38936,779,153 - 36,797,334 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl936,779,159 - 36,797,393 (-)EnsemblGRCm38mm10GRCm38
MGSCv37936,586,740 - 36,604,653 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36936,528,826 - 36,546,739 (-)NCBIMGSCv36mm8
Celera933,981,501 - 33,999,718 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map920.68NCBI
Ei24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8844,683,138 - 44,699,502 (-)NCBIGRCr8
mRatBN7.2836,494,289 - 36,510,653 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl836,494,289 - 36,510,571 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx840,503,825 - 40,520,077 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0838,786,883 - 38,803,143 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0836,649,771 - 36,666,023 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0839,254,883 - 39,271,238 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,254,889 - 39,266,959 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,257,600 - 39,273,481 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4838,028,043 - 38,044,316 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1838,036,808 - 38,053,082 (-)NCBI
Celera837,930,578 - 37,946,563 (+)NCBICelera
Cytogenetic Map8q22NCBI
Ei24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541226,574,866 - 26,585,161 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541226,574,814 - 26,586,154 (+)NCBIChiLan1.0ChiLan1.0
EI24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29126,258,080 - 126,273,317 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111127,362,564 - 127,377,780 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011120,389,136 - 120,404,347 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111124,302,289 - 124,317,346 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11124,302,289 - 124,317,346 (+)Ensemblpanpan1.1panPan2
EI24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.158,949,886 - 8,963,967 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl58,950,883 - 8,963,967 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha58,995,125 - 9,009,082 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.058,890,483 - 8,904,437 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl58,890,357 - 8,904,437 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.158,962,275 - 8,976,216 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.058,932,736 - 8,946,687 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.058,969,329 - 8,983,282 (-)NCBIUU_Cfam_GSD_1.0
Ei24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947107,708,434 - 107,722,877 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367431,958,829 - 1,969,540 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367431,957,948 - 1,970,885 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EI24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl952,704,570 - 52,720,938 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1952,704,560 - 52,724,966 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2958,354,873 - 58,374,166 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EI24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11116,711,922 - 116,727,208 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1116,714,578 - 116,726,216 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660439,343,470 - 9,358,915 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004874495   ⟹   XP_004874552
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249271,548,837 - 1,566,108 (+)NCBI
RefSeq Acc Id: XM_004874496   ⟹   XP_004874553
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249271,548,664 - 1,566,108 (+)NCBI
RefSeq Acc Id: XM_004874497   ⟹   XP_004874554
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249271,548,544 - 1,566,108 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004874552 (Get FASTA)   NCBI Sequence Viewer  
  XP_004874553 (Get FASTA)   NCBI Sequence Viewer  
  XP_004874554 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012677
  ENSHGLP00000045366
  ENSHGLP00100060461
Reference Protein Sequences
RefSeq Acc Id: XP_004874554   ⟸   XM_004874497
- UniProtKB: A0A0P6J6R8 (UniProtKB/TrEMBL),   G5APE8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004874553   ⟸   XM_004874496
- UniProtKB: A0A0P6J6R8 (UniProtKB/TrEMBL),   G5APE8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004874552   ⟸   XM_004874495
- UniProtKB: A0A0P6J6R8 (UniProtKB/TrEMBL),   G5APE8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009064 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100004038 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000012814 ENTREZGENE
  ENSHGLT00000080623 UniProtKB/TrEMBL
  ENSHGLT00100048712 UniProtKB/TrEMBL
KEGG Report hgl:101699601 UniProtKB/TrEMBL
NCBI Gene Ei24 ENTREZGENE
PANTHER ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG UniProtKB/TrEMBL
  PTHR21389 UniProtKB/TrEMBL
Pfam EI24 UniProtKB/TrEMBL
UniProt A0A0P6J6R8 ENTREZGENE, UniProtKB/TrEMBL
  G5APE8 ENTREZGENE, UniProtKB/TrEMBL