EI24 (EI24 autophagy associated transmembrane protein) - Rat Genome Database

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Gene: EI24 (EI24 autophagy associated transmembrane protein) Sus scrofa
Analyze
Symbol: EI24
Name: EI24 autophagy associated transmembrane protein
RGD ID: 13976235
Description: ENCODES a protein that exhibits importin-alpha family protein binding (inferred); INVOLVED IN autophagy (ortholog); cellular response to UV-C (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); ASSOCIATED WITH Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog); holoprosencephaly 11 (ortholog); FOUND IN cytosol (inferred); endoplasmic reticulum (inferred); Golgi apparatus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: etoposide induced 2.4 mRNA; etoposide-induced protein 2.4 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl952,704,570 - 52,720,938 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1952,704,560 - 52,724,966 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2958,354,873 - 58,374,166 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
EI24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl952,704,570 - 52,720,938 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1952,704,560 - 52,724,966 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2958,354,873 - 58,374,166 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EI24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811125,569,477 - 125,584,684 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11125,569,280 - 125,584,684 (+)EnsemblGRCh38hg38GRCh38
GRCh3711125,439,373 - 125,454,579 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,944,508 - 124,959,785 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411124,944,507 - 124,959,784NCBI
Celera11122,599,610 - 122,614,886 (+)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11121,380,862 - 121,396,124 (+)NCBIHuRef
CHM1_111125,325,451 - 125,340,728 (+)NCBICHM1_1
T2T-CHM13v2.011125,598,125 - 125,613,333 (+)NCBIT2T-CHM13v2.0
Ei24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39936,690,449 - 36,708,630 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl936,690,455 - 36,708,689 (-)EnsemblGRCm39 Ensembl
GRCm38936,779,153 - 36,797,334 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl936,779,159 - 36,797,393 (-)EnsemblGRCm38mm10GRCm38
MGSCv37936,586,740 - 36,604,653 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36936,528,826 - 36,546,739 (-)NCBIMGSCv36mm8
Celera933,981,501 - 33,999,718 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map920.68NCBI
Ei24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8844,683,138 - 44,699,502 (-)NCBIGRCr8
mRatBN7.2836,494,289 - 36,510,653 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl836,494,289 - 36,510,571 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx840,503,825 - 40,520,077 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0838,786,883 - 38,803,143 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0836,649,771 - 36,666,023 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0839,254,883 - 39,271,238 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,254,889 - 39,266,959 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,257,600 - 39,273,481 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4838,028,043 - 38,044,316 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1838,036,808 - 38,053,082 (-)NCBI
Celera837,930,578 - 37,946,563 (+)NCBICelera
Cytogenetic Map8q22NCBI
Ei24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541226,574,866 - 26,585,161 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541226,574,814 - 26,586,154 (+)NCBIChiLan1.0ChiLan1.0
EI24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29126,258,080 - 126,273,317 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111127,362,564 - 127,377,780 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011120,389,136 - 120,404,347 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111124,302,289 - 124,317,346 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11124,302,289 - 124,317,346 (+)Ensemblpanpan1.1panPan2
EI24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.158,949,886 - 8,963,967 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl58,950,883 - 8,963,967 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha58,995,125 - 9,009,082 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.058,890,483 - 8,904,437 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl58,890,357 - 8,904,437 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.158,962,275 - 8,976,216 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.058,932,736 - 8,946,687 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.058,969,329 - 8,983,282 (-)NCBIUU_Cfam_GSD_1.0
Ei24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947107,708,434 - 107,722,877 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367431,958,829 - 1,969,540 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367431,957,948 - 1,970,885 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EI24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11116,711,922 - 116,727,208 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1116,714,578 - 116,726,216 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660439,343,470 - 9,358,915 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ei24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249271,548,544 - 1,566,108 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EI24
335 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 2
Low 10 4 3 4 2 21 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000016579   ⟹   ENSSSCP00000016134
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl952,704,570 - 52,720,938 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000048278   ⟹   ENSSSCP00000049933
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl952,704,601 - 52,752,996 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000085321   ⟹   ENSSSCP00000061633
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl952,704,601 - 52,720,288 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000096566   ⟹   ENSSSCP00000077735
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl952,715,189 - 52,720,936 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000098568   ⟹   ENSSSCP00000077630
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl952,704,588 - 52,720,936 (+)Ensembl
RefSeq Acc Id: XM_003130045   ⟹   XP_003130093
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1952,704,560 - 52,721,387 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002335716
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1952,704,560 - 52,724,966 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_003130093   ⟸   XM_003130045
- UniProtKB: A0A4X1VJ06 (UniProtKB/TrEMBL),   A0A480ECU0 (UniProtKB/TrEMBL),   A0A8W4FH42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000016134   ⟸   ENSSSCT00000016579
RefSeq Acc Id: ENSSSCP00000049933   ⟸   ENSSSCT00000048278
RefSeq Acc Id: ENSSSCP00000077735   ⟸   ENSSSCT00000096566
RefSeq Acc Id: ENSSSCP00000061633   ⟸   ENSSSCT00000085321
RefSeq Acc Id: ENSSSCP00000077630   ⟸   ENSSSCT00000098568


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015213 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005041607 UniProtKB/TrEMBL
  ENSSSCG00065047957 UniProtKB/TrEMBL
  ENSSSCG00070024209 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016579.5 UniProtKB/TrEMBL
  ENSSSCT00000085321 ENTREZGENE
  ENSSSCT00000085321.2 UniProtKB/TrEMBL
  ENSSSCT00000096566.1 UniProtKB/TrEMBL
  ENSSSCT00000098568 ENTREZGENE
  ENSSSCT00000098568.1 UniProtKB/TrEMBL
  ENSSSCT00005066624.1 UniProtKB/TrEMBL
  ENSSSCT00065065639.1 UniProtKB/TrEMBL
  ENSSSCT00070048336.1 UniProtKB/TrEMBL
  ENSSSCT00070048341.1 UniProtKB/TrEMBL
  ENSSSCT00070048346.1 UniProtKB/TrEMBL
KEGG Report ssc:100511341 UniProtKB/TrEMBL
NCBI Gene EI24 ENTREZGENE
PANTHER ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG UniProtKB/TrEMBL
  PTHR21389 UniProtKB/TrEMBL
Pfam EI24 UniProtKB/TrEMBL
UniProt A0A480ECU0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VGC2_PIG UniProtKB/TrEMBL
  A0A4X1VJ06 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0KHC8_PIG UniProtKB/TrEMBL
  A0A8W4FFU0_PIG UniProtKB/TrEMBL
  A0A8W4FH42 ENTREZGENE, UniProtKB/TrEMBL
  F1S776_PIG UniProtKB/TrEMBL
UniProt Secondary A0A5G2QI06 UniProtKB/TrEMBL
VGNC ID VGNC:87602 ENTREZGENE